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Oxyntomodulin. Group: Biochemicals. Grades: Purified. CAS No. 62340-29-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Oxyntomodulin (30-37) (bovine, dog, porcine)
Synonyms: GLUCAGON FRAGMENT 30-37; H-LYS-ARG-ASN-LYS-ASN-ASN-ILE-ALA-OH; glucagon 37 fragment 30-37; glicentin (62-69). CAS No. 81117-26-2. Molecular formula: C39H72N16O12. Mole weight: 957.09.
Oxyntomodulin (bovine, porcine)
Oxyntomodulin (bovine, porcine), a 37-amino acid peptide hormone, is a glucagon-like peptide 1 (GLP-1) receptor agonist [1]. Uses: Scientific research. Group: Peptides. Alternative Names: Glucagon-37 (bovine, porcine). CAS No. 62340-29-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1144.
Oxyntomodulin (human, mouse, rat)
Oxyntomodulin (human, mouse, rat) can effectively inhibit gastric acid secretion and pancreatic enzyme secretion when infused iv. Furthermore, Oxyntomodulin injection into the intraventricular and hypothalamic paraventricular nucleus effectively and consistently inhibits food intake in both fasted and non-fasted animals. Synonyms: OXM (human, mouse, rat); H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-Lys-Arg-Asn-Arg-Asn-Asn-Ile-Ala-OH; Preproglucagon (53-89) (human, mouse, rat); Proglucagon (33-69) (human, mouse, rat); Glucagon-37 (human, mouse, rat); L-histidyl-L-seryl-L-glutaminyl-glycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-aspartyl-L-tyrosyl-L-seryl-L-lysyl-L-tyrosyl-L-leucyl-L-alpha-aspartyl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-glutaminyl-L-alpha-aspartyl-L-phenylalanyl-L-valyl-L-glutaminyl-L-tryptophyl-L-leucyl-L-methionyl-L-asparagyl-L-threonyl-L-lysyl-L-arginyl-L-asparagyl-L-arginyl-L-asparagyl-L-asparagyl-L-isoleucyl-L-alanine. Grades: 95%. CAS No. 159002-68-3. Molecular formula: C192H295N61O60S. Mole weight: 4449.83.
Oxyntomodulin (human, mouse, rat)
Oxyntomodulin (human, mouse, rat) (Proglucagon (33-69)) is a product of the glucagon precursor. Oxyntomodulin (human, mouse, rat) contains the entire glucagon sequence plus a C-terminal octapeptide, comprising in total 37 amino acids. Uses: Scientific research. Group: Peptides. Alternative Names: Proglucagon (33-69). CAS No. 159002-68-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P4796.
Oxyntomodulin (porcine, bovine)
Oxyntomodulin is a naturally peptide hormone found in the colon, produced by the oxyntic (fundic) cells of the oxyntic (fundic) mucosa. It has been found to suppress appetite. Oxyntomodulin acts as a glucagon-like peptide 1 (GLP-1) receptor agonist. Synonyms: Glucagon (1-37), porcine; Oxyntomodulin, porcine; His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-Lys-Arg-Asn-Lys-Asn-Asn-Ile-Ala. Grades: ≥96% by HPLC. CAS No. 62340-29-8. Molecular formula: C192H295N59O60S. Mole weight: 4421.86.
BETP
BETP is a positive allosteric modulator and partial agonist of the glucagon-like peptide 1 (GLP-1) receptor, displaying no effect on GLP-2, GIP, PTH or glucagon receptors. BETP promotes oxyntomodulin binding to GLP-1 receptor. It potentiates oxyntomodulin-mediated GLP-1 receptor signaling in vitro and insulin secretion in vivo. Synonyms: 2-(Ethylsulfinyl)-4-[3-(phenylmethoxy)phenyl]-6-(trifluoromethyl)pyrimidine. Grades: ≥98% by HPLC. CAS No. 1371569-69-5. Molecular formula: C20H17F3N2O2S. Mole weight: 406.42.
Mazdutide
Mazdutide (IBI-362; LY-3305677) is a long-acting synthetic oxyntomodulin analog. Mazdutide is also a co-agonist of glucagon-like peptide ( GLP-1R ) and glucagon receptor ( GCGR ). Mazdutide binds human and mouse GCGR ( K i : 17.7 nM and 15.9 nM, respectively) and GLP-1R ( K i : 28.6 nM and 25.1 nM, respectively) and stimulates insulin secretion from mouse islets ( EC 50 : 5.2 nM). Mazdutide is used in studies of obesity and type 2 diabetes (T2D) [1] [2] [3]. Uses: Scientific research. Group: Peptides. Alternative Names: IBI-362; LY-3305677; OXM-3. CAS No. 2259884-03-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P3375.
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