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| Product | Description | |
|---|---|---|
| Palbociclib | 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one. Grades: 98%. CAS No. 571190-30-2. Product ID: 8-05160. Molecular formula: C24H29N7O2. Mole weight: 447.53. |  |
| Palbociclib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Palbociclib | Palbociclib Inhibitor. Uses: Scientific use. Product Category: T1785. CAS No. 571190-30-2. |  |
| Palbociclib | Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD 0332991. CAS No. 571190-30-2. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767. |  |
| Palbociclib | Palbociclib (PD 0332991) is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Palbociclib;571190-30-2;PD0332991;Ibrance;PD-0332991;PD 0332991;UNII-G9ZF61LE7G;Palbociclib free base;Palbociclib-d8;6-acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one;PD-332991;571190-30-2 (free base);MFCD11840850;6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE;6-Acetyl-8-cyclopentyl-5-m. Product Category: Inhibitors. CAS No. 571190-30-2. Molecular formula: C24H29N7O2. Mole weight: 447.5g/mol. Purity: 0.9994. IUPACName: 6-acetyl-8-cyclopentyl-5-methyl-2-[(5-piperazin-1-ylpyridin-2-yl)amino]pyrido[2,3-d]pyrimidin-7-one. Canonical SMILES: CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C. Product ID: ACM571190302. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Palbociclib, Free Base Salt, 99+% | PD 0332991 is a potent selective inhibitor of cyclin dependent kinases CDK4 and CDK6 with in vitro IC50 = 11 nM (CDK4) and 16 nM (CDK6). PD 0332991 induces G1 arrest in retinoblastoma (Rb)-positive tumor cells. Group: Biochemicals. Alternative Names: 6-acetyl-8-cyclopentyl-5-methyl-2- [ [5- (1-piperazinyl) -2-pyridinyl]amino]pyrido [2, 3-d]pyrimidin-7 (8H) -one 2-hydroxy-ethanesulfonic acid (1:1); PD0332991; Palbociclib; isethionate. Grades: Highly Purified. CAS No. 571190-30-2. Pack Sizes: 25mg, 50mg, 100mg. US Biological Life Sciences. |  Worldwide |
| Palbociclib HCl | Palbociclib, also known as PD0332991, is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. PD-0332991 selectively inhibits cyclin-dependent kinases (particularly Cdk4/cyclin D1 kinase), which may inhibit retinoblastoma (Rb) protein phosphorylation; inhibition of Rb phosphorylation prevents Rb-positive tumor cells from entering the S phase of the cell cycle (arrest in the G1 phase), resulting in suppression of DNA replication and decreased tumor cell proliferation. PD 0332991 is a highly specific inhibitor of cyclin-dependent kinase 4 (Cdk4) (IC50=0.011 μmol/L) and Cdk6 (IC50=0.016 μmol/L), having no activity against a panel of 36 additional protein kinases. Synonyms: PD 0332991; PD 332991; PD0332991; PD-0332991; Palbociclib hydrochloride. Grades: >98%. CAS No. 827022-32-2. Molecular formula: C24H29N7O2.HCl. Mole weight: 483.99. |  |
| Palbociclib hydrochloride | Palbociclib (PD 0332991) hydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC 50 values of 11 and 16 nM, respectively. Palbociclib hydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells. Palbociclib hydrochloride can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma [1] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PD-0332991 hydrochloride. CAS No. 571189-11-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-50767C. | |
| Palbociclib Impurity 002 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C14H21BrN4. Mole weight: 325.25. | |
| Palbociclib Impurity 022 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-Butyl 4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; 1779124-68-3; tert-Butyl4-(2-nitropyridin-3-yl)piperazine-1-carboxylate; SCHEMBL17550837; CS-0448403; EN300-7455913. Grades: 95%. CAS No. 1779124-68-3. Molecular formula: C14H20N4O4. Mole weight: 308.33. | |
| Palbociclib Impurity 025 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: N-Formyl Palbociclib; Palbociclib Impurity F; Palbociclib N-Aldehyde; Palbociclib N-Formyl Impurity. Grades: 95%. CAS No. 2174002-16-3. Molecular formula: C25H29N7O3. Mole weight: 475.54. | |
| Palbociclib Impurity 026 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C28H37N7O2. Mole weight: 503.64. | |
| Palbociclib Impurity 027 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C27H35N7O2. Mole weight: 489.61. | |
| Palbociclib Impurity 028 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Molecular formula: C18H24N4O. Mole weight: 312.41. | |
| Palbociclib Impurity 029 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(2-nitropyridin-3-yl)piperazine; 1566082-34-5; GS0805; EN300-2138375. Grades: 95%. CAS No. 1566082-34-5. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 030 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(4-nitropyridin-3-yl)piperazine; GS0814; 1211541-02-4. Grades: 95%. CAS No. 1211541-02-4. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 10 | Palbociclib Impurity 10 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-Piperazinecarboxylic acid, 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis-, 1,1'-bis(1,1-dimethylethyl) ester; 1,1'-Bis(1,1-dimethylethyl) 4,4'-[(8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]bis[1-piperazinecarboxylate]; Bis(2-methyl-2-propanyl) 4,4'-[(8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-2,6-diyl)bis(imino-2,5-pyridinediyl)]di(1-piperazinecarboxylate). Grades: 95%. CAS No. 2206135-30-8. Molecular formula: C41H55N11O5. Mole weight: 781.94. | |
| Palbociclib Impurity 11 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Grades: > 95%. Molecular formula: C33H45N7O4. Mole weight: 603.77. | |
| Palbociclib Impurity 12 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: tert-butyl 4-(6-((2-chloro-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-6-yl)amino)pyridin-3-yl)piperazine-1-carboxylate. Grades: > 95%. Molecular formula: C27H34ClN7O3. Mole weight: 540.07. | |
| Palbociclib Impurity 13 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 2-acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. Grades: > 95%. Molecular formula: C24H29N7O2. Mole weight: 447.54. | |
| Palbociclib Impurity 13 TriHCl | Palbociclib Impurity 13 TriHCl is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-acetyl-8-cyclopentyl-5-methyl-6-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one, hydrochloride (1:3). Molecular formula: C24H32N7O2Cl3. Mole weight: 583.92. | |
| Palbociclib Impurity 14 | Palbociclib Impurity 14 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Butenoic acid, 2-(2,2-dimethoxyethyl)-, methyl ester; methyl (Z)-2-(2,2-dimethoxyethyl)but-2-enoate; 2-Butenoicacid,2-(2,2-dimethoxyethyl)-,methylester. CAS No. 51534-87-3. Molecular formula: C9H16O4. Mole weight: 188.22. | |
| Palbociclib Impurity 15 | Palbociclib Impurity 15 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: methyl 2-acetyl-4,4-dimethoxybutanoate; Butanoic acid, 2-acetyl-4,4-dimethoxy-, methyl ester; Butanoicacid,2-acetyl-4,4-dimethoxy-,methylester. CAS No. 51534-82-8. Molecular formula: C9H16O5. Mole weight: 204.22. | |
| Palbociclib Impurity 16 | Palbociclib Impurity 16 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C8H12O5. Mole weight: 188.18. | |
| Palbociclib Impurity 17 | Palbociclib Impurity 17 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 1-(Triphenylphosphoranylidene)propan-2-one; 1-(Triphenylphosphoranylidene)-2-propanone; 1-(Triphenylphosphoranylidene)acetone. Grades: >98.0%. CAS No. 1439-36-7. Molecular formula: C21H19OP. Mole weight: 318.36. | |
| Palbociclib Impurity 18 | Palbociclib Impurity 18 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 1-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)ethanone; 1-[2-Chloro-4-(cyclopentylamino)-5-pyrimidinyl]ethanone; 1-[2-chloro-4-(cyclopentylamino)pyrimidin-5-yl]ethanone; 1-(2-chloro-4-(cyclopentylamino)pyrimidin-5-yl)ethan-1-one. CAS No. 1244949-62-9. Molecular formula: C11H14ClN3O. Mole weight: 239.7. | |
| Palbociclib Impurity 18 | Palbociclib Impurity 18. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1244949-62-9. Molecular formula: C11H14ClN3O. Mole weight: 239.7. Catalog: APB1244949629. | |
| Palbociclib Impurity 2 | Palbociclib Impurity 2 is an impurity of Palbociclib, which is a selective cyclin-dependent kinases CDK4 and CDK6 inhibitor used for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: Desoxo-palbociclib; Pyrido[2,3-d]pyrimidin-7(8H)-one, 8-cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-; 8-Cyclopentyl-6-ethenyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]pyrido[2,3-d]pyrimidin-7(8H)-one; Palbociclib Impurity D. Grades: 95%. CAS No. 2204863-06-7. Molecular formula: C24H29N7O. Mole weight: 431.53. | |
| Palbociclib Impurity 2 | Palbociclib Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1072-97-5. Molecular formula: C5H5BrN2. Mole weight: 173.01. Catalog: APB1072975. | |
| Palbociclib Impurity 22 | Palbociclib Impurity 22 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-((2-aminoethyl)amino)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 571191-15-6. Molecular formula: C22H27N7O2. Mole weight: 421.51. | |
| Palbociclib Impurity 23 | Palbociclib Impurity 23 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-8-cyclopentyl-5-methyl-2-((3-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 2205035-04-5. Molecular formula: C24H29N7O2. Mole weight: 447.54. | |
| Palbociclib Impurity 24 | Palbociclib Impurity 24 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-Acetyl-8-cyclopentyl-2-((3,6-di(piperazin-l-yl)pyridin-2-yl)amino)-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Molecular formula: C44H52Br2N14O2. Mole weight: 968.8. | |
| Palbociclib Impurity 24 | Palbociclib Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1013916-37-4. Molecular formula: C13H14ClN3O. Mole weight: 263.72. Catalog: APB1013916374. | |
| Palbociclib Impurity 27 | Palbociclib Impurity 27 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-Acetyl-8-cyclopentyl-2-[(3,6-di-1-piperazinyl-2-pyridinyl)amino]-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 2459303-21-8. Molecular formula: C28H37N9O2. Mole weight: 531.67. | |
| Palbociclib Impurity 29 | Palbociclib Impurity 29 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2458234-43-8. Molecular formula: C27H33Br2N7O3. Mole weight: 663.42. | |
| Palbociclib Impurity 30 | Palbociclib Impurity 30 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C22H26ClN7O. Mole weight: 439.95. | |
| Palbociclib Impurity 33 | Palbociclib Impurity 33 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: (6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)glycine. CAS No. 2363160-84-1. Molecular formula: C22H24N6O4. Mole weight: 436.47. | |
| Palbociclib Impurity 35 | Palbociclib Impurity 35 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 1-(6-Nitro-3-pyridinyl)piperazine; 1-(6-Nitropyridin-3-yl)piperazine. CAS No. 775288-71-6. Molecular formula: C9H12N4O2. Mole weight: 208.22. | |
| Palbociclib Impurity 36 | Palbociclib Impurity 36 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 1,4-Bis(6-nitro-3-pyridyl)piperazine; 1,4-Bis(6-nitropyridin-3-yl)piperazine; 1,4-bis(6-nitropyridin-3-yl)piperazine? (Palbociclib Impurity pound(c). CAS No. 2340184-77-0. Molecular formula: C14H14N6O4. Mole weight: 330.3. | |
| Palbociclib Impurity 36 | Palbociclib Impurity 36. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 4-(2-aminopyridin-3-yl)piperazine-1-carboxylate. CAS No. 1023594-49-1. Molecular formula: C14H22N4O2. Mole weight: 278.35. Catalog: APB1023594491. | |
| Palbociclib Impurity 37 | Palbociclib Impurity 37 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2144748-14-9. Molecular formula: C14H18N6. Mole weight: 270.34. | |
| Palbociclib Impurity 38 | Palbociclib Impurity 38 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-(1-Butoxyethenyl)-8-cyclopentyl-5-methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-pyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 2270982-31-3. Molecular formula: C28H37N7O2. Mole weight: 503.65. | |
| Palbociclib Impurity 4 | An impurity of Palbociclib which is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor to treat ER-positive and HER2-negative breast cancer. Synonyms: Pyrido[2,?3-d]?pyrimidin-7(8H)?-one, 8-cyclopentyl-6-(1-hydroxyethyl)?-5-methyl-2-[[5-(1-piperazinyl)?-2-pyridinyl]?amino]?-. Grades: > 95%. CAS No. 1376615-91-6. Molecular formula: C24H31N7O2. Mole weight: 449.56. | |
| Palbociclib Impurity 40 | Palbociclib Impurity 40 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H35N3O. Mole weight: 393.58. | |
| Palbociclib Impurity 41 | Palbociclib Impurity 41 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C19H24BrN3O. Mole weight: 390.33. | |
| Palbociclib Impurity 42 | Palbociclib Impurity 42 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido-[2,3-d]pyrimidin-7(8H)-one. Grades: 98%. CAS No. 1016636-76-2. Molecular formula: C13H13BrClN3O. Mole weight: 342.62. | |
| Palbociclib Impurity 46 | Palbociclib Impurity 46 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 8-Cyclopentyl-5-methylpyrido[2,3-d]pyrimidine-2,7(1H,8H)-dione. CAS No. 2375089-01-1. Molecular formula: C13H15N3O2. Mole weight: 245.28. | |
| Palbociclib Impurity 47 | Palbociclib Impurity 47 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-Bromo-2-chloropyrimidin-4(3H)-one; 5-Bromo-2-chloro-4(3H)-pyrimidinone; 5-Bromo-2-chloropyrimidin-4-ol. Grades: 95%. CAS No. 844843-37-4. Molecular formula: C4H2BrClN2O. Mole weight: 209.43. | |
| Palbociclib Impurity 48 | Palbociclib Impurity 48 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C40H42Br2N12O2. Mole weight: 882.67. | |
| Palbociclib Impurity 49 | Palbociclib Impurity 49 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 4-[6-[(6-Acetyl-8-cyclopentyl-7,8-dihydro-5-methyl-7-oxopyrido[2,3-d]pyrimidin-2-yl)amino]-3-pyridinyl]-γ-oxo-1-piperazinebutanoic acid. CAS No. 1974279-21-4. Molecular formula: C28H33N7O5. Mole weight: 547.62. | |
| Palbociclib Impurity 5 | An impurity of Palbociclib which is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)-5-(piperazin-1-yl)pyridine 1-oxide. Grades: > 95%. Molecular formula: C24H30N7O3. Mole weight: 464.55. | |
| Palbociclib Impurity 50 | Palbociclib Impurity 50 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H29N7O4. Mole weight: 491.55. | |
| Palbociclib Impurity 51 | Palbociclib Impurity 51 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-(4-butylpiperazin-1-yl)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. Molecular formula: C28H37N7O2. Mole weight: 503.65. | |
| Palbociclib Impurity 53 | Palbociclib Impurity 53 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-bromo-2-chloro-N-cyclopentyl-4-pyrimidinamine; 5-bromo-2-chloro-N-cyclopentylpyrimidin-4-amine. Grades: >95%. CAS No. 733039-20-8. Molecular formula: C9H11BrClN3. Mole weight: 276.56. | |
| Palbociclib Impurity 54 | Palbociclib Impurity 54 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Chloro-N-cyclopentyl-4-pyrimidinamine; (2-Chloropyrimidin-4-yl)(cyclopentyl)amine. CAS No. 868591-58-6. Molecular formula: C9H12ClN3. Mole weight: 197.67. | |
| Palbociclib Impurity 55 | Palbociclib Impurity 55 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 5-Bromo-N,N-dicyclopentyl-2,4-pyrimidinediamine. CAS No. 2444702-87-6. Molecular formula: C14H21BrN4. Mole weight: 325.25. | |
| Palbociclib Impurity 56 | Palbociclib Impurity 56 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-(4-acetylpiperazin-1-yl)pyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 1974279-20-3. Molecular formula: C26H31N7O3. Mole weight: 489.58. | |
| Palbociclib Impurity 57 | Palbociclib Impurity 57 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H27N7O3. Mole weight: 461.53. | |
| Palbociclib Impurity 58 | Palbociclib Impurity 58 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 6-acetyl-2-((5-aminopyridin-2-yl)amino)-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one. CAS No. 2363172-64-7. Molecular formula: C20H22N6O2. Mole weight: 378.44. | |
| Palbociclib Impurity 59 | Palbociclib Impurity 59 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H25N7O4. Mole weight: 475.51. | |
| Palbociclib Impurity 6 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer. Synonyms: 1-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine 1-oxide. Grades: > 95%. Molecular formula: C24H29N7O3. Mole weight: 463.54. | |
| Palbociclib Impurity 6 | Palbociclib Impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 153747-97-8. Molecular formula: C14H20BrN3O2. Mole weight: 342.23. Catalog: APB153747978. | |
| Palbociclib Impurity 62 | Palbociclib Impurity 62 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H35N7O8. Mole weight: 621.65. | |
| Palbociclib Impurity 63 | Palbociclib Impurity 63 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Synonyms: 2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one; 2-Chloro-8-cyclopentyl-5-methyl-8H-pyrido[2,3-d]pyrimidin-7-one. Grades: 97%. CAS No. 1013916-37-4. Molecular formula: C13H14ClN3O. Mole weight: 263.73. | |
| Palbociclib Impurity 64 | Palbociclib Impurity 64 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C25H31N7O3. Mole weight: 477.57. | |
| Palbociclib Impurity 65 | Palbociclib Impurity 65 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C24H29N7O3. Mole weight: 463.54. | |
| Palbociclib Impurity 66 | Palbociclib Impurity 66 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. Molecular formula: C30H35N7O8. Mole weight: 621.65. | |
| Palbociclib Impurity 67 | Palbociclib Impurity 67 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 2242625-36-9. Molecular formula: C13H16ClN3O2. Mole weight: 281.74. | |
| Palbociclib Impurity 69 | Palbociclib Impurity 69 is an impurity of Palbociclib, a medication for the treatment of HR-positive and HER2-negative breast cancer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6. CAS No. 1023594-50-4. Molecular formula: C14H22N4O2. Mole weight: 278.36. | |
| Palbociclib Impurity 7 | An impurity of Palbociclib which is a drug for the treatment of ER-positive and HER2-negative breast cancer used in combination with letrozole (an aromatase inhibitor). Synonyms: 1-Piperazinecarboxylic acid, 4-[6-[[6-[(1E)?-2-butoxyethenyl]?-8-cyclopentyl-7,?8-dihydro-5-methyl-7-oxopyrido[2,?3-d]?pyrimidin-2-yl]?amino]?-3-pyridinyl]?-, 1,?1-dimethylethyl ester. Grades: > 95%. CAS No. 827022-35-5. Molecular formula: C33H45N7O4. Mole weight: 603.77. | |
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