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| Product | Description | |
|---|---|---|
| Pamapimod | Pamapimod. Group: Biochemicals. Alternative Names: 6- (2, 4-Difluorophenoxy) -2-[[3-hydroxy-1- (2-hydroxyethyl) propyl]amino]-8-methylpyrido[2, 3-d]pyrimidin-7 (8H) -one; R 1503; Ro 4402257. Grades: Highly Purified. CAS No. 449811-01-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C19H20F2N4O4. US Biological Life Sciences. |  Worldwide |
| Pamapimod | Pamapimod (Ro4402257) is a potent, selective and orally active p38 MAPK inhibitor with IC50s of 14 nM and 480 nM and Kis of 1.3 nM and 120 nM for p38? and p38?, respectively. Pamapimod has no activity against p38? or p38? isoforms. Pamapimod has the potential for rheumatoid arthritis and other autoimmune diseases treatment[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro4402257; R1503. CAS No. 449811-01-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10405. |  |
| Pamapimod-[d4] | Pamapimod-[d4] is the labelled analogue of Pamapimod, which is a selective inhibitor of the α-isoform of p38 MAP kinase. Synonyms: Pamapimod-d4; 6-(2,4-Difluorophenoxy)-2-[[3-hydroxy-1-(2-hydroxyethyl)propyl]amino]-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one-d4. Grade: 95% by HPLC; 95% atom D. CAS No. 1246814-57-2. Molecular formula: C19H16D4F2N4O4. Mole weight: 410.4. |  |
| (2,4-Difluorophenoxy)acetic Acid Methyl Ester | (2,4-Difluorophenoxy)acetic Acid Methyl Ester is an intermediate in the synthesis of Pamapimod (P167500), a selective inhibitor of the α-isoform of p38 MAP kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 449811-63-6. Pack Sizes: 100mg, 250mg. Molecular Formula: C9H8F2O3. US Biological Life Sciences. | Worldwide |
| 3-Amino-1,5-pentanediol | 3-Amino-1,5-pentanediol is an substituent in the synthesis of Pamapimod (P167500), a selective inhibitor of the α-isoform of p38 MAP kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1117-23-3. Pack Sizes: 10mg, 50mg. Molecular Formula: C5H13NO2. US Biological Life Sciences. | Worldwide |
| 3-[(Phenylmethyl)amino]-1,5-pentanediol | 3-[(Phenylmethyl)amino]-1,5-pentanediol is an protected substituent in the synthesis of Pamapimod (P167500), a selective inhibitor of the α-isoform of p38 MAP kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 1034082-96-6. Pack Sizes: 25mg, 100mg. Molecular Formula: C12H19NO2. US Biological Life Sciences. | Worldwide |
| 3-[ (Phenylmethyl) amino]pentanedioic Acid Dimethyl Ester | 3-[ (Phenylmethyl) amino]pentanedioic Acid Dimethyl Ester 3-[ (Phenylmethyl) amino]pentanedioic Acid Dimethyl Ester is an protected substituent in the synthesis of Pamapimod (P167500), a selective inhibitor of the α-isoform of p38 MAP kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 109270-76-0. Pack Sizes: 50mg, 250mg. Molecular Formula: C14H19NO4. US Biological Life Sciences. | Worldwide |
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