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Paraoxamide A is a mycotoxin derived from the fungus Penicillium. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors. The structure of parherquamide, a toxic metabolite from Penicillium paraherquei. Synonyms: VM 29919. Grades: >95% by HPLC. CAS No. 77392-58-6. Molecular formula: C28H35N3O5. Mole weight: 493.59.
Paraherquamide A (Antibiotic VM 29919)
Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent non-toxic paralysis of nematodes which led to the metabolite's development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors. Group: Biochemicals. Alternative Names: Antibiotic VM 29919. Grades: Highly Purified. CAS No. 77392-58-6. Pack Sizes: 1mg. US Biological Life Sciences.
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Paraherquamide E
A member of the paraherquamide family which causes a potent non-toxic paralysis of nematode. It is a fungal metabolite originally isolated from Penicillium charlesii with anthelmintic and insecticidal activities. Synonyms: Antibiotic VM 54159; VM 54159; 14-Deoxyparaherquamide A; (1'S, 5'aS, 7'R, 8'aS, 9'aR) -2', 3', 8'a, 9'-tetrahydro-1', 4, 4, 8', 8', 11'-hexamethyl-spiro[4H, 8H-[1, 4]dioxepino[2, 3-g]indole-8, 7' (8'H) -[5H, 6H-5a, 9a] (iminomethano) [1H]cyclopent[f]indolizine]-9, 10' (10H) -dione. Grades: >99% by HPLC. CAS No. 125600-53-5. Molecular formula: C28H35N3O4. Mole weight: 477.60.
Paraherquamide E
Paraherquamide E is a fungal metabolite found in Penicillium charlesii. Paraherquamide E has antinematodal and antiparasitic effects [1]. Uses: Scientific research. Group: Natural products. CAS No. 125600-53-5. Pack Sizes: 500 μg. Product ID: HY-N10220.
Paraherquamide E (Antibiotic VM 54159, 14-Deoxy-paraherquamide A)
Paraherquamide E is a member of the paraherquamide family which cause a potent non-toxic paralysis of nematodes and has led to the investigation of their potential as anthelmintics. Although paraherquamide A has received more attention, paraherquamide E has been shown to be the more potent anthelmintic in vivo. Paraherquamide E was found to be the most potent insecticide in a series of paraherquamide analogues against a hemipteran with an LD50 of 0.089 ug/nymph. Group: Biochemicals. Alternative Names: Antibiotic VM 54159, 14-Deoxy-paraherquamide A. Grades: Highly Purified. CAS No. 125600-53-5. Pack Sizes: 500ug. US Biological Life Sciences.
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brevianamide F prenyltransferase (deoxybrevianamide E-forming)
The enzyme from the fungus Aspergilus sp. MF297-2 is specific for brevianamide F, while the enzyme from Aspergillus versicolor accepts a broad range of trytophan-containing cyclic dipeptides. Involved in the biosynthetic pathways of several indole alkaloids such as paraherquamides and malbrancheamides. Group: Enzymes. Synonyms: NotF; BrePT; brevianamide F reverse prenyltransferase. Enzyme Commission Number: EC 2.5.1.109. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2725; brevianamide F prenyltransferase (deoxybrevianamide E-forming); EC 2.5.1.109; NotF; BrePT; brevianamide F reverse prenyltransferase. Cat No: EXWM-2725.
Derquantel
Derquantel is a semi-synthetic paraherquamide analogue prepared by removal of the 2-oxo group in a four-step sequence of N-protection. Derquantel is an effective nematicide, which can act as a nicotinic acetylcholine receptor antagonist agent, causing flaccid paralysis and nematode repellent. Synonyms: 2-Deoxoparaherquamide; 2-Deoxoparaherquamide A; 2-Desoxoparaherquamide A; PF 00520904; PNU 141962. Grades: >98% by HPLC. CAS No. 187865-22-1. Molecular formula: C28H37N3O4. Mole weight: 479.61.
Marcfortine A (Antibiotic UK 111866)
Marcfortine A is an indole alkaloid isolated from Aspergillus and Pencillium species with potent nematocidal activity. The marcfortines are structurally related to paraherquamides and thought to act by blockade of cholinergic neuromuscular transmission. Group: Biochemicals. Alternative Names: Antibiotic UK 111866. Grades: Highly Purified. CAS No. 75731-43-0. Pack Sizes: 1mg. US Biological Life Sciences.
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