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Parecoxib (SC 69124) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 69124. CAS No. 198470-84-7. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17474.
Parecoxib-[d3]
Parecoxib-[d3] is a labelled Parecoxib. Parecoxib is a selective COX-2 inhibitor and a prodrug of valdecoxib approved for the control of short term perioperative pain. Synonyms: Parecoxib-D3; 4-(5-Methyl-D3-3-phenylisoxazol-4-yl)-N-propionyl-benzenesulfonamide; Dynastat-d3; N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamide-d3. Grade: 95% by HPLC; 98% atom D. Molecular formula: C19H15D3N2O4S. Mole weight: 373.44.
The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days. The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision. Uses: Cyclooxygenase 2 inhibitors. Synonyms: sodium ((4-(5-methyl-3-phenylisoxazol-4-yl)phenyl)sulfonyl)(propionyl)amide; Parecoxib sodium; SC-69124A; SC 69124A; SC69124A; Dynastat. Grade: >98%. CAS No. 198470-85-8. Molecular formula: C19H17N2NaO4S. Mole weight: 392.4.
Parecoxib Sodium
?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: SC 69124A, Parecoxib sodium, Rayzon,Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, sodium salt (1:1), Propanamide, N-[[4-(5-methyl-3-phenyl-4-isoxazolyl)phenyl]sulfonyl]-, sodium salt (9CI), Dynastat.
Parecoxib Sodium (SC 69124A) is a highly selective and orally active COX-2 inhibitor, the proagent of Valdecoxib (HY-15762). Parecoxib Sodium is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits prostaglandin (PG) synthesis. Parecoxib Sodium can be used for the relief of acute postoperative pain and symptoms of chronic inflammatory conditions such as osteoarthritis and rheumatoid arthritis in vivo. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SC 69124A. CAS No. 198470-85-8. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-17474A.
Parecoxib Sodium
Parecoxib Sodium. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Sodium (4-(5-methyl-3-phenylisoxazol-4-yl)phenylsulfonyl)(propionyl)amide. CAS No. 198470-85-8. Molecular formula: C19H17N2NaO4S. Mole weight: 392.4. Purity: ≥98%. Product ID: ACM198470858. Alfa Chemistry ISO 9001:2015 Certified.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonamide, 2-(5-methyl-3-phenyl-4-isoxazolyl)-; Parecoxib Impurity 48. CAS No. 2304623-35-4. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 37. CAS No. 2304623-37-6. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 09. CAS No. 386273-25-2. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
3-methyl-4,5-diphenylisoxazole
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 38. CAS No. 75115-00-3. Molecular formula: C16H13NO. Mole weight: 235.28.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 39; Benzenesulfonamide, 4-(3-methyl-5-phenyl-4-isoxazolyl)-. Grade: 98%. CAS No. 181695-84-1. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 15; Valdecoxib Impurity 13. CAS No. 2251048-58-3. Molecular formula: C16H15N3O5S2. Mole weight: 393.43.
4-(4-chlorophenyl)-5-methyl-3-phenylisoxazole
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 40. CAS No. 1448355-87-0. Molecular formula: C16H12ClNO. Mole weight: 269.72.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 29. CAS No. 2338845-31-9. Molecular formula: C32H24N2O4S. Mole weight: 532.61.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Parecoxib Impurity 47. Grade: >95%. CAS No. 2242749-01-3. Molecular formula: C16H14N2O3S. Mole weight: 314.36.
An impurity of Parecoxib which is a COX2 selective inhibitor and a water-soluble and injectable prodrug of valdecoxib. Synonyms: Benzenesulfonic acid, 4-(5-methyl-3-phenyl-4-isoxazolyl)-, ethyl ester; Parecoxib Impurity 27. Grade: >95%. CAS No. 1884279-18-8. Molecular formula: C18H17NO4S. Mole weight: 343.40.