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| Product | Description | |
|---|---|---|
| Paxilline | A tremorgenic mycotoxin isolated from species of penicillium, acremonium and emericella. It selectively blocks high-conductance ca2+-activated potassium channels and inhibits binding to the cerebellar inositol 1,4,5-triphosphate (insp(3)) receptor. Grades: >99% by HPLC. CAS No. 57186-25-1. Molecular formula: C27H33NO4. Mole weight: 435.55. |  |
| Paxilline | Paxilline is an indole alkaloid mycotoxin derived from Penicillium paxilli, which effectively inhibits the BK channel through a channel-blocking mechanism. Paxilline also inhibits sarco/endoplasmic reticulum Ca2+-stimulated ATPase (SERCA), with IC50 values ranging from 5 ?M to 50 ?M for different SERCA isoforms. Paxilline exhibits significant anticonvulsant and neuroprotective effects, as well as certain antioxidant activity[1][2][3][4][5][6]. Uses: Scientific research. Group: Natural products. CAS No. 57186-25-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N6778. |  |
| Paxilline | Paxilline is a tremorgenic mycotoxin isolated from species of Penicillium, Acremonium and Emericella. Paxilline acts as a selective blocker of high-conductance Ca2+-activated potassium channels and has been shown to inhibit binding to the cerebellar inositol 1,4,5-triphosphate (InsP(3)) receptor. Group: Biochemicals. Grades: Highly Purified. CAS No. 57186-25-1. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| Paxilline | powder, ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Anti-phospho-Paxillin (pTyr118) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-Paxillin (pTyr31) antibody produced in rabbit | affinity isolated antibody, buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Anti-phospho-Paxillin (pTyr31) antibody produced in rabbit | affinity isolated antibody. Group: Fluorescence/luminescence spectroscopy. | |
| KY 05009 | KY 05009 is an inhibitor of Traf2- and Nck-Interacting Kinase (TNIK; Ki value 100 nM in ATP competitive assay) that attenuates TGF-β1-mediated Wnt and Smad signaling and epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma A549 cells. In addition, KY05009 inhibits TGF-β1-induced phosphorylation of JNK1/2, FAK, Src, and paxillin. Synonyms: KY 05009; KY05009; KY-05009; 5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide; 2-anilino-5-[(4-methylbenzoyl)amino]-1,3-thiazole-4-carboxamide. Grades: 99%. CAS No. 1228280-29-2. Molecular formula: C18H16N4O2S. Mole weight: 352.41. | |
| Monoclonal Anti-Paxillin antibody produced in mouse | clone PXC-10, ascites fluid. Group: Fluorescence/luminescence spectroscopy. | |
| Paxillin, pY31, Negative Control Peptide (PXN) | Paxillin, pY31, Negative Control Peptide (PXN). Group: Molecular Biology. Grades: Purified. Pack Sizes: 1x100ug. US Biological Life Sciences. | Worldwide |
| Paxillin, pY31, Positive Control Peptide (PXN) | Paxillin, pY31, Positive Control Peptide (PXN). Group: Molecular Biology. Grades: Purified. Pack Sizes: 1x100ug. US Biological Life Sciences. | Worldwide |
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