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Protein Synthesis Initiation Factor 2a (pS51), Negative Control Peptide
Protein Synthesis Initiation Factor 2a (pS51), Negative Control Peptide. Group: Molecular Biology. Alternative Names: ILLSELpSRRRIR ILLSELSRRRIR. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Protein Synthesis Initiation Factor 2a (pS51), Positive Control Peptide
Protein Synthesis Initiation Factor 2a (pS51), Positive Control Peptide. Group: Molecular Biology. Alternative Names: ILLSELpSRRRIR ILLSELSRRRIR. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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11-Aminoundecanoic acid
11-Aminoundecanoic acid also known as aminoundecanoic acid, is utilized in solution phase peptidesynthesis. It is also a monomer precursor for nylon-11. Uses: 11-aminoundecanoic acid can be used as a linker to synthesize amide-linked linear guanosine dimer. Group: Amino acids. Alternative Names: Aminoundecanoic acid. CAS No. 2432-99-7. Molecular formula: NH2(CH2)10CO2H. Mole weight: 201.31. Appearance: White powder. Purity: 0.98. IUPACName: 11-Aminoundecanoic acid. Canonical SMILES: NCCCCCCCCCCC(O)=O. Density: 0.989 g/ml. ECNumber: 219-417-6. Catalog: ACM2432997-1.
1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose
The chemical compound, 1,2,3,4,6-Penta-O-trimethylsilyl-D-glucopyranose, plays a pivotal role as a chemical reagent in the pharmaceutical and biotech industries. Its varied synthesis usage in the creation of nucleosides, peptides, and oligonucleotides reflects its significance in the development of drugs intended to treat and combat nucleic acid-related disorders, such as DNA and RNA implicated ailments. Synonyms: 1,2,3,4,6-Pentakis-O-(trimethylsilyl)-D-glucopyranose; 1,2,3,4,6-Penta-trimethylsilyl Glucopyranose; trimethyl-[[(2R,3R,4S,5R)-3,4,5,6-tetrakis(trimethylsilyloxy)oxan-2-yl]methoxy]silane; D-Glucopyranose, 5TMS. CAS No. 19126-99-9. Molecular formula: C21H52O6Si5. Mole weight: 541.07.
Commonly known as EDAC, EDC or EDCI, this carbodiimide HCl salt is used as a coupling reagent in the synthesis of amides and carboxylic esters. EDAC is highly soluble in water and in most organic solvents, it can be employed in liquid and solid-phase and synthesis. The major advantage of EDCI over other carbodiimides such as DCC and DIC is the ease of purification of the product from the water-soluble urea by-product by washing the crude mixture with water or mild acid and extracting in the organic phase. The main applications of EDAC are in peptidesynthesis, Steglich esterification reactions in presence of catalytic DMAP, immunoconjugate synthesis, synthesis of sulfo-NHS esters and coupling of biomolecules onto solid supports. Group: Biochemicals. Alternative Names: EDC.HCl; EDAC. HCl; Water Soluble Carbodiimide; N-Ethyl-N'- (3-dimethylaminopropyl) carbodiimide HCl; 1-Ethyl-3- (3-dimethylaminopropyl) carbodiimide HCl. Grades: Highly Purified. CAS No. 25952-53-8. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C8H17N3·HCl, Molecular Weight: 191.7. US Biological Life Sciences.
1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride is a carbodiimide reagent that can form nucleic acid and compounds with amide bonds. 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride accelerates the formation reaction of esters, amides, and peptides, as a condensing and dehydrating agent, which are often used for polynucleotide synthesis, anhydroxydation, lactonization and esterification [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 25952-53-8. Pack Sizes: 5 g; 10 g. Product ID: HY-D0178.
17-Chloro-androsta-5,16-dien-3 β-ol
17-Chloro-androsta-5,16-dien-3 β-ol is a derivative of Dehydro Epiandrosterone (D229585), which is a major secretory steroidal product of the adrenal gland. Dehydro Epiandrosterone may have estrogen-or androgen-like effects depending on the hormonal milieu, and is used in the treatment of menopausal syndrome. 17-Chloro-androsta-5,16-dien-3 β-ol is also used in the synthesis of peptides and derivatives as inhibitors for Schistosoma japonica glutathione s-transferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 13592-95-5. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H27ClO, Molecular Weight: 306.87. US Biological Life Sciences.
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1,9-Diaminononane trityl resin
Diamines are attached to trityl resins to ensure the minimum of trityl diamine cross-linking. A reagent for solid phase peptidesynthesis. Synonyms: NH2-(CH2)9-NH-Trt-Resin; Diaminononane-Trt-Resin.
1-Acetylimidazole
Acetylating agent for capping unreacted amino groups in peptidesynthesis. Synonyms: 1-(1H-imidazol-1-yl)ethanone. Grades: ≥ 98% (Titration). CAS No. 2466-76-4. Molecular formula: C5H6N2O. Mole weight: 110.10.
1-Amino-1-cyclopentanemethanol
1-Amino-1-cyclopentanemethanol is a reagent used in the synthesis of novel human natriuretic peptide receptor A agonists, which may be useful in the treatment of heart failure. Group: Biochemicals. Grades: Highly Purified. CAS No. 10316-79-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C6H13NO, Molecular Weight: 115.17. US Biological Life Sciences.
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1-Fmoc-amino-2,4-O-D-butane-2,3,4-triol
Fmoc-amino-2,4-O-D-butane-2,3,4-triol, an organic compound highly regarded in the spheres of biochemistry and organic chemistry, is a key starting material used in the synthesis of diversified biologically active compounds. Its amine group manifests aptitude for reacting with carboxylic acids or anhydrides, consequently forming amide linkages that aid in generating peptides and proteins pervasive in biological systems. Fmoc-amino-2,4-O-D-butane-2,3,4-triol shows immense promise in drug discovery and development and has the potential to treat diseases resulting from abnormal protein interactions through novel mechanisms.
1-Hydroxy-7-azabenzotriazole
HOAT can be used as a coupling additive for efficient racemization-free coupling in peptidesynthesis. Synonyms: HOAt; [1,2,3]Triazolo[4,5-b]pyridin-3-ol; 1H-[1,2,3]triazolo[4,5-b]pyridine 3-Oxide; 3H-[1,2,3]triazolo[4,5-b]pyridin-3-ol; 3-hydroxytriazolo[4,5-b]pyridine; 3H-1,2,3-Triazolo[4,5-b]pyridine, 3-hydroxy-; UNII-TX8XYH09H0; HOAT 1M DMA Solution; HOAT [1-Hydroxy-7-azabenzotriazole]; TX8XYH09H0; 7-Aza-1-hydroxybenzotriazole; 1,2,3-triazolo[5,4-b]pyridin-3-ol; HOAt Form I; HOAt Form II. Grades: ≥ 98%. CAS No. 39968-33-7. Molecular formula: C5H4N4O. Mole weight: 136.11.
1-L-Prolyl-L-proline Hydrochloride
1-L-Prolyl-L-proline Hydrochloride, is a building block used in the synthesis of various compounds such as in synthetic preparation of bis-cystinyl cyclic peptides. Group: Biochemicals. Grades: Highly Purified. CAS No. 76932-06-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C10H16N2O3; HCl, Molecular Weight: 248.713646. US Biological Life Sciences.
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1-Methyl-2-pyrrolidinone, distilled 99+.8% (GC)
For peptidesynthesis. Group: Biochemicals. Alternative Names: N-Methyl-2-ketopyrrolidine; N-Methyl-2-pyrrolidinone. Grades: GC. CAS No. 872-50-4. Pack Sizes: 100ml, 250ml, 1L, 4L, 16L. Molecular Formula: C5H9NO, Molecular Weight: 99.13. US Biological Life Sciences.
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(1R, 3S) -3-Aminocyclopentane carboxylic Acid
(1R, 3S) -3-Aminocyclopentane carboxylic Acid is used in the synthesis of aminocyclopentane carboxylic acid-containing cyclic RGD peptides. It is also used to prepare BMS-457, a potent and selective CCR1 antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 71830-08-5. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H11NO2, Molecular Weight: 129.16. US Biological Life Sciences.
(1R,3S,4S)-tert-Butyl 3-(1H-Benzo[d]imidazol-2-yl)-2-azabicyclo[2. 2. 1]heptane-2-carboxylate can be obtained from (R)-(+)-α-Methylbenzylamine (M288800) which can be used as reactant/reagent in synthesis of urea-containing peptide boronic acids as proteasome inhibitors. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C18H23N3O2, Molecular Weight: 313.39. US Biological Life Sciences.
1R, 3S, 5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3. 1. 0]hexane-3-carboxylic Acid acts as a reagent in the preparation of fused bicycles end-capped with peptide derivatives as HCV inhibitors. Synthesis of (tert-butoxycarbonyl) azabicyclohexane carboxylic acid via stereoselective cyclopropanation of pyrroline. Group: Biochemicals. Grades: Highly Purified. CAS No. 197142-34-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C11H17NO4, Molecular Weight: 227.26. US Biological Life Sciences.
[(1S)-2-Phenyl-1-[(2R)-tetrahydro-5-oxo-2-furanyl]ethyl]carbamic Acid 1,1-Dimethyethyl Ester is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (A β), the major causative agent in Alzheimer disease (AD). Group: Biochemicals. Grades: Highly Purified. CAS No. 135130-98-2. Pack Sizes: 100mg, 1g. Molecular Formula: C17H23NO4. US Biological Life Sciences.
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2, 2-Diethoxyethane thioamide
2, 2-Diethoxyethane thioamide is an intermediate in the synthesis of Tubulysin M, an antimitotic peptide from myxobacteria. Group: Biochemicals. Grades: Highly Purified. CAS No. 73956-15-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C6H13NO2S, Molecular Weight: 163.24. US Biological Life Sciences.
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2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl azide
2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl azide, a vital reagent employed in the biomedical sector, exhibits its prowess in glycoconjugate synthesis. Its remarkable azido group incorporation capability allows for biomolecule modification, primarily proteins and peptides. The compound's significance resonates in the realm of targeted drug delivery systems and diagnostic devices, revolutionizing the fight against select cancers and infectious ailments. Synonyms: 2,3,4,6-Tetra-O-acetyl-a-D-galactopyranosyl azide; [(2R,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-azidooxan-2-yl]methyl acetate; 2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GALACTOPYRANOSYL AZIDE; DTXSID10461082; (2R,3S,4S,5R,6S)-2-[(Acetyloxy)methyl]-6-azidooxane-3,4,5-triyl triacetate (non-preferred name). CAS No. 94427-00-6. Molecular formula: C14H19N3O9. Mole weight: 373.32.
2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl-(N2-Fmoc)-L-threonine pentafluorophenyl ester, an essential chemical compound in the biomedicine industry, serves as the precursor for the synthesis of glycopeptide antibiotics. Its unique ability to form peptide bonds with amino groups makes it the perfect candidate for treating infectious diseases like MRSA. Its impact in the field of medicine is significant, representing a breakthrough in the development of new therapeutic interventions. Its versatile applications in this field make it indispensable for biomedical research and drug discovery, and it continues to be a promising target for future studies. Synonyms: (2S,3S,4S,5R,6R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)((2S,3R)-3-hydroxy-1-oxo-1-(perfluorophenoxy)butan-2-yl)amino)-6-(acetoxymethyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 152389-15-6. Molecular formula: C39F5H36NO14. Mole weight: 837.71.
2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl-N-Fmoc-L-serine pentafluorophenyl ester holds significant potential in the realm of drug design, particularly in the synthesis of glycopeptides targeting various diseases, such as cancer. In solid-phase peptidesynthesis, this compound is employed as a reagent to link serine residues to mannose, generating peptidomimetics with varied biological and medicinal significance. The uniform utilization of 2,3,4,6-tetra-O-acetyl-a-D-mannopyranosyl-N-Fmoc-L-serine pentafluorophenyl ester highlights its importance in biochemical endeavors aimed at improving human health. CAS No. 152389-14-5. Molecular formula: C38F5H34NO14. Mole weight: 823.68.
2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl-(N2-Fmoc)-L-serine, a fundamental chemical constituent utilized extensively in the biomedical sector, functions astoundingly well as a peptide building block in solid phase peptidesynthesis, serving as a remarkable tool for developing and investigating peptides' potential in various disease treatment and drug discovery. The chemical structure's intricate and complex features enable its applications to be distinguished and, subsequently, used in biomedicine, thus imparting it with multifaceted attributes. Synonyms: N-Fmoc-O-(2,3,4,6-tetra-O-acetyl-β-D-galactopyranosyl)-L-serine; Galactosylated L-serine; Fmoc-L-Ser(β-D-Gal(Ac)4)-OH; N-(9H-Fluorene-9-ylmethoxycarbonyl)-O-(2-O,3-O,4-O,6-O-tetraacetyl-beta-D-galactopyranosyl)-L-serine; N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(2,3,4,6-tetra-O-acetyl-beta-D-galactopyranosyl)-L-serine. Grades: ≥95%. CAS No. 96383-44-7. Molecular formula: C32H35NO14. Mole weight: 657.63.
2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl-(N2-Fmoc)-L-serine pentafluorophenyl ester, a sophisticated chemical compound widely employed in the biomedical arena, serves as a valuable reagent in peptidesynthesis. Its fundamental role in drug development for ailments ranging from cancer to diabetes exhibits its exceptional utility in the field of medicine and elucidates its significance in biomedical research. Synonyms: (2R,3R,4S,5S,6R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)((S)-3-hydroxy-1-oxo-1-(perfluorophenoxy)propan-2-yl)amino)-6-(acetoxymethyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. CAS No. 243469-45-6. Molecular formula: C38F5H34NO14. Mole weight: 823.68.
2,3,4,6-Tetra-O-acetyl-b-D-galactopyranosyl-(N2-Fmoc)-L-threonine is a biomedical compound commonly utilized in the development and synthesis of peptide-based drugs. It plays a crucial role as a protecting group for the amino acid threonine during peptidesynthesis. With its precise chemical properties, it ensures the accurate and controlled assembly of peptide sequences, making it an tool in drug development and disease research. Synonyms: Fmoc-L-Thr(beta-D-Gal(Ac)4)-OH. CAS No. 127656-85-3. Molecular formula: C33H37NO14. Mole weight: 671.65.
2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-Fmoc serine is a globally recognized bioactive compound, finding its utility in the synthesis of innovative glycosylated peptides. Synonyms: Fmoc-L-Ser(Beta-D-Glc(Ac)4)-OH; N-(9H-Fluorene-9-Ylmethoxycarbonyl)-O-(2-O,3-O,4-O,6-O-Tetraacetyl-Beta-D-Glucopyranosyl)-L-Serine. CAS No. 118358-38-6. Molecular formula: C32H35NO14. Mole weight: 657.63.
2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-(N2-Fmoc)-L-asparagine tert-butyl ester, a complex chemical entity, finds extensive application in the realm of peptide drug development. Being a crucial glycosylated asparagine building block in solid phase peptidesynthesis, it exhibits an inherent ability to serve as a potent therapeutic modality for combatting cancer and autoimmune disorders. Its multifarious applications in biochemistry and molecular biology make it an indispensable tool for researchers and scientists striving to unravel the complex mechanisms underlying various diseases. CAS No. 160416-17-1. Molecular formula: C37H44N2O14. Mole weight: 740.75.
2,3,4,6-Tet-ra-O-ac-etyl-b-D-glu-copy-ran-osyl-N-F-moc-L-ser-ine pent-aflu-oroph-en-yl ester, a vital chemical agent in the field of biomedical research, finds application in the synthesis of peptides to study complex cell signaling pathways in diverse clinical conditions. The versatility of this reagent is further accentuated when utilized with other reactants to enhance peptidesynthesis efficacy and augment output yield. This multidimensional compound has immense potential in investigating potential therapeutics for formidable diseases ranging from Alzheimer's to cancer. CAS No. 478062-63-4. Molecular formula: C38F5H34NO14. Mole weight: 823.68.
2,3,4,6-Tetra-O-acetyl-b-D-glucopyranosyl-N-Fmoc-L-threonine pentafluorophenyl ester, a chemical compound featured in the peptidesynthesis, finds its widespread utility as a versatile reagent for the synthesis of therapeutic peptides and proteins. Diseases including Alzheimer's disease, diabetes, and cancer can be mitigated by the therapeutic efficacy of peptides and proteins. Given its crucial role, this compound is commonly present in several research laboratories that conduct peptidesynthesis. Molecular formula: C39F5H36NO14. Mole weight: 837.71.
2,3,4-Tri-O-acetyl-b-D-xylopyranosyl-Fmoc-L-serine is a highly sought after organic compound that exerts tremendous impact on the biomedical industry due to its ability to facilitate the synthesis of peptides or proteins. It is a valuable material as it contributes to the development of novel therapeutic agents tailored to address diseases and disorders that results from protein or peptide deficiencies. Its outstanding contribution in this regard is underscored by the fact that it is frequently employed as a protected amino acid derivative for peptidesynthesis. Notably, it possesses immense potential in treating autoimmune diseases and certain hormonal imbalances characterized by diminished protein/peptide levels, thus, justifying its significance in the scientific community. Molecular formula: C29H31NO12. Mole weight: 585.56.
2,4-Difluorobenzeneacetic Acid
2,4-Difluorophenylacetic acid is used in the synthesis of nonpolar peptide nucleic acid monomers containing fluoroaromatics (F-PNA). Group: Biochemicals. Grades: Highly Purified. CAS No. 81228-09-3. Pack Sizes: 1g, 5g. Molecular Formula: C8H6F2O2, Molecular Weight: 172.13. US Biological Life Sciences.
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2,4-Dimethoxybenzylamine hydrochloride
Reagent for protection of amide function in glutamine and asparagine during peptidesynthesis. Synonyms: (2,4-dimethoxyphenyl)methanamine hydrochloride; 2,4-Dimethoxybenzylamine HCl. Grades: 97 %. CAS No. 20781-21-9. Molecular formula: C9H13NO2·HCl. Mole weight: 203.67.
2,5-Piperazinedione, can be used as an intermediate in the preparation of various pharmaceutical and biologically active compounds. It can be used in the synthesis of dipeptide isosteres by cross-metathesis. Group: Biochemicals. Alternative Names: 2,5-Diketopiperazine; 2,5-Dioxopiperazine; Cyclo(Gly-Gly); Cyclo(glycylglycyl); Cyclodiglycine; Cycloglycylglycine; Diglycolyl Diamide; Diketopiperazine; Glycine Cyclic Dimer; N-glycylglycine Cyclic Peptide; Glycylglycine Lactam; NSC 26345; α,γ-Diacipiperazine. Grades: Highly Purified. CAS No. 106-57-0. Pack Sizes: 1g, 10g. Molecular Formula: C?H?N?O?, Molecular Weight: 114.1. US Biological Life Sciences.
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-galactopyranosyl-(N-Fmoc)-L-serine pentafluorophenyl ester is an essential and sophisticated chemical reagent in peptidesynthesis. It introduces considerable burstiness and perplexity in developing therapeutic peptides, which characteristically treat cancer and infectious diseases. Its adoption in peptide coupling reactions is a crucial implementation for the progression of scientific and medical research. CAS No. 137816-29-6. Molecular formula: C38F5H35N2O13. Mole weight: 822.69.
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-a-D-glucopyranosyl-Fmoc asparagine, a vital compound in the synthesis of bioactive peptides and glycopeptides, has garnered attention in the scientific community for its outstanding potential in the study of various diseases. Its significance is attributed to its shielding capacity as a protecting group for asparagine residues that precludes any unwanted reactions during peptidesynthesis. Moreover, due to its unique attribute of influencing both protein structure and function, it exhibits promise in the study of malignancies such as cancer. Molecular formula: C33H37N3O13. Mole weight: 683.66.
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl-Fmoc threonine is a glycosylated amino acid used in the synthesis of Fmoc solid-phase peptide. Synonyms: GlcNAc L-threonine; Fmoc-Thr(GlcNAc(Ac)3-b-D)-OH; Fmoc-L-Thr(beta-D-GlcNAc(Ac)3)-OH; N-alpha-(9-Fluorenylmethyloxycarbonyl)-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-beta-D-glucopyranosyl)-L-threonine; O-[3-O,4-O,6-O-Triacetyl-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-N-Fmoc-L-threonine. Grades: ≥95%. CAS No. 160168-40-1. Molecular formula: C33H38N2O13. Mole weight: 670.66.
2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-b-D-glucopyranosyl-(N-Fmoc)-L-serine pentafluorophenyl ester is a biomedical product commonly used in drug synthesis and research. This compound serves as a versatile building block in the creation of peptides and glycoconjugates for studying protein interactions, drug delivery systems, and medicinal chemistry. Its pentafluorophenyl ester moiety facilitates efficient coupling reactions, making it valuable in drug discovery and development processes. CAS No. 160410-57-1. Molecular formula: C38F5H35N2O13. Mole weight: 822.68.
2-(Boc-amino)ethanthiol (CAS# 67385-09-5) is used in the synthesis of several organic compounds including a novel, anisamide-targeted cyclodextrin nanoformulation for the delivery of siRNA to prostate cancer cells which is a potential therapeutic option. Also used in the synthesis of bifunctional azobenzene glycoconjugates for cysteine-based photosensitive cross-linking with bioactive peptides. Synonyms: (2-Mercaptoethyl)carbamic Acid 1,1-Dimethylethyl Ester; (2-Mercaptoethyl)carbamic acid tert-butyl ester; 1,1-Dimethylethyl (2-mercaptoethyl)carbamate; 2-(N-tert-Butoxycarbonylamino)ethanethiol; 2-(tert-Butoxycarbonylamino)ethanethiol; 2-(tert-Butoxycarbonylamino)ethylmercaptan; 2-[(tert-Butoxycarbonyl)amino]-1-ethanethiol; 2-tert-Butylcarbamate-ethanethiol; N-Boc-2-aminoethanethiol; N-tert-Butoxycarbonyl-2-aminoethanethiol; N-tert-Butoxycarbonylcysteamine; tert-Butyl (2-mercaptoethyl)carbamate; tert-Butyl (2-sulfanylethyl)carbamate; tert-Butyl-N-(2-mercaptoethyl)carbamate. Grades: 90 %. CAS No. 67385-09-5. Molecular formula: C7H15NO2S. Mole weight: 177.26.
2-(Boc-amino)ethanthiol (>90%)
2-(Boc-amino)ethanthiol is used in the synthesis of several organic compounds including a novel, anisamide-targeted cyclodextrin nanoformulation for the delivery of siRNA to prostate cancer cells which is a potential therapeutic option. Also used in the synthesis of bifunctional azobenzene glycoconjugates for cysteine-based photosensitive cross-linking with bioactive peptides. Group: Biochemicals. Grades: Highly Purified. CAS No. 67385-09-5. Pack Sizes: 1g, 5g. Molecular Formula: C7H15NO2S. US Biological Life Sciences.
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2-Chlorotrityl Chloride
2-Chlorotrityl Chloride is used in convergent peptidesynthesis. 2-Chlorotrityl Chloride is also used in the preparation of modified trityl nucleosides as inhibitors of P. falciparum dUTPase. Group: Biochemicals. Grades: Highly Purified. CAS No. 42074-68-0. Pack Sizes: 1g, 10g. Molecular Formula: C19H14Cl2. US Biological Life Sciences.
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2-Chlorotrityl Chloride Resin
Amino acids can be attached to 2-Cl-Trt chloride resin with very little or no racemization. The steric bulk of 2-chlorotrityl chloride resin inhibits diketopiperazine formation, which can be a major side reaction in the synthesis of peptides with C-terminal proline. Uses: 2-chlorotrityl chloride resin can be cleaved under extremely mild acid conditions that leave boc/tbu based protecting groups in place. thus it is used to prepare protected peptide fragments. Group: Unsubstituted resins. Alternative Names: 2-Cl-Trt chloride resin. Pack Sizes: 25g, 100g.
2-Deoxy-1,3,4,6-tetra-O-pivaloyl-D-glucopyranose
2-Deoxy-1,3,4,6-tetra-O-pivaloyl-D-glucopyranose, a critical molecule utilized in peptidesynthesis as an amino acid shielding agent, holds immense value in the realm of biomedical research. The scientific community also acknowledges its significance in generating therapeutically potent sialyl Lewis X mimetics that deter cancer cell adhesion. The diverse applications of this compound cement its position as an essential component for achieving successful outcomes in biomedicine. Molecular formula: C26H44O9. Mole weight: 500.64.
2-Ethyl-2-methyl-1,3-dioxolane
2-Ethyl-2-methyl-1,3-dioxolane is used as a reagent in the synthesis of Strychnine Hydrochloride (S687710); a compound that acts as an antagonist for cholinesterases and beta amyloid aggregation. Also used as a reagent in the study of the prodrugs of peptide aldehyde as proteasome inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 126-39-6. Pack Sizes: 1g, 10g. Molecular Formula: C6H12O2, Molecular Weight: 116.16. US Biological Life Sciences.
(2-Isopropylthiazol-4-yl)methanamine Dihydrochloride is a reagent in the synthesis of heteroarylmethyl amides which are used as HDL-raising agents. (2-Isopropylthiazol-4-yl)methanamine Dihydrochloride is also a reagent in the preparation of peptide analogs. Group: Biochemicals. Grades: Highly Purified. CAS No. 1171981-10-4. Pack Sizes: 5mg, 10mg. Molecular Formula: C7H14Cl2N2S, Molecular Weight: 229.17. US Biological Life Sciences.
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2-Methylazetidine Hydrochloride
2-Methylazetidine Hydrochloride is a starting material in synthesis of compounds as bacterial peptide deformylase inhibitors useful in treatment of bacterial infections. Group: Biochemicals. Grades: Highly Purified. CAS No. 1152113-37-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C4H9N; HCl, Molecular Weight: 71.1236459999999. US Biological Life Sciences.
(2R, ? 4R) ? -? 1-? Boc-? N-? Fmoc-? 4-? amino-? pyrrolidine-? 2-? carboxylic Acid can be used as reactant/reagent in synthetic preparation of KMI-008 peptide derivatives and proline-based peptidomimetic analogs and determination of their activity as BACE1 inhibitors ( β-secretase inhibitors). It can also be used as reagent/reactant for preparation of aminoproline residues for solid phase synthesis of integrin binding cyclic peptides by bromination, azidation and protection / deprotection protocol. Group: Biochemicals. Grades: Highly Purified. CAS No. 1018332-24-5. Pack Sizes: 50mg, 100mg. Molecular Formula: C25H28N2O6, Molecular Weight: 452.5. US Biological Life Sciences.
(2S,3R)-Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir is the isomer of Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir (D290330), which is an intermediate for the synthesis of Atazanavir and the preparation of some peptide analogs. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C32H42N4O5, Molecular Weight: 562.7. US Biological Life Sciences.
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(2S,3S)-Fmoc-Abu(3-N3)-OH
A useful tool for the synthesis of branched, side-chain modified, cyclic peptides and peptide tools for click chemistry. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols or phosphines. Uses: Peptidesynthesis. Group: Amino acids. Alternative Names: (2S,3S)-Fmoc-Abu(3-N3)-OH, (2S,3S)-2-(Fmoc-amino)-3-azidobutanoic acid. CAS No. 131669-42-6. Mole weight: 366.37. Catalog: ACM131669426.
(2S,3S)-(Fmoc-amino)-3-azidobutyric acid
Protected derivative for the synthesis of 2,3-diaminobutanoic acid containing peptides and also for click reactions. Synonyms: Fmoc-L-Abu(3S-N3)-OH; (2S,3S)-Fmoc-abu(3-n3)-oh; (2S,3S)-(Fmoc-amino)-3-azidobutyric acid; (2S,3S)-3-azido-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanoic acid. Grades: ≥ 99% (Assay by titration, HPLC, TLC). CAS No. 131669-42-6. Molecular formula: C19H18N4O4. Mole weight: 366.40.
(2S, 4S) -4-Amino-1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) Ester
(2S, 4S) -4-Amino-1, 2-pyrrolidinedicarboxyl ic Acid 1-(1,1-Dimethylethyl) Ester is used to prepare aminoproline residues for solid phase synthesis of integrin binding cyclic peptides. Group: Biochemicals. Grades: Highly Purified. CAS No. 132622-66-3. Pack Sizes: 500mg, 5g. Molecular Formula: C10H18N2O4, Molecular Weight: 230.26. US Biological Life Sciences.
It is used as an amino protective reagent in peptidesynthesis. Synonyms: 2-Butoxycarbonyloximino-2-phenylAcetonitrile; BOC-ON 25GR; BOC-ON 5GR; BOC-ON; 2-(tert-Butoxycarbonyloxyimino)-2-phenylAcetonitrile; 2-(Boc-oxyimino)-2-phenylAcetonitrile; Carbonic acid, (cyanophenylmethylene)azanyl 1,1-dimethylethyl ester; N-((tert-Butoxycarbonyl)oxy)benzimidoyl cyanide; EINECS 261-370-9; (Z)-N-(tert-butoxycarbonyloxy)benzimidoyl cyanide; Boc-ON. Grades: ≥ 99 % (HPLC). CAS No. 58632-95-4. Molecular formula: C13H14N2O3. Mole weight: 246.26.
2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le
2- (tert-Butoxycarbonyl oxyimino) phenyl acetonitri le is used as a reagent in the synthesis of phosphono methyl ornithine. Also used in the preparation of cholesterol-tagged natural fusion-protein-derived peptides with potent antiviral activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 58632-95-4. Pack Sizes: 5g, 10g. Molecular Formula: C13H14N2O3. US Biological Life Sciences.
It is being used for the synthesis of amides. EDC HCl is also used as a coupling agent in the preparation of esters from carboxylic acids using dimethylaminopyridine as the catalyst. It is water-soluble carbodiimide, widely used for peptide coupling. Synonyms: EDC.HCL; 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride; EDC hydrochloride; EDCI; 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride; 1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide Hydrochloride [Coupling Agent; EDAP; 1-Ethyl-3-(3-dimethyllaminopropyl)carbodiimide hydrochloride; edac hcl; wsc hcl; N1-((Ethylimino)methylene)-N3,N3-dimethylpropane-1,3-diamine hydrochloride. Grades: 98%. CAS No. 25952-53-8. Molecular formula: C8H17N3·HCl. Mole weight: 191.70.
3,5-Diaminobenzoic acid
Peptidesynthesis. Group: Amino acids. Alternative Names: 3,5-DABA, 5-Carboxy-1,3-phenylenediamine, DABA. CAS No. 535-87-5. Molecular formula: (H2N)2C6H3CO2H. Mole weight: 152.15. Canonical SMILES: Nc1cc(N)cc(c1)C(O)=O. ECNumber: 208-621-0. Catalog: ACM535875-2.
3- (Benzyl oxycarbonyl amino) propionalde hyde is used as a reagent in the synthesis of Tuberactinomycin N, a peptide antibiotic that is used as an anti-tuberculotic drug. 3- (Benzyl oxycarbonyl amino) propionalde hyde is also used as a reagent to prepare L-epicapreomycidine, a guanidino amino acid that is naturally found in hydrolyzates of protease inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 65564-05-8. Pack Sizes: 1g, 5g. Molecular Formula: C11H13NO3, Molecular Weight: 207.23. US Biological Life Sciences.
Used in the synthesis of peptides containing geranyltryptophan. Group: Biochemicals. Grades: Highly Purified. CAS No. 862704-32-3. Pack Sizes: 100mg. US Biological Life Sciences.
3-(Diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one is a peptide coupling reagent used in peptidesynthesis. It shows remarkable resistance to racemization. Synonyms: Diethyl 3,4-Dihydro-4-oxo-1,2,3-benzotriazin-3-yl Phosphate; diethyl (4-oxo-1,2,3-benzotriazin-3-yl) phosphate; Diethyl (4-oxobenzo[d][1,2,3]triazin-3(4H)-yl) phosphate; 3-(diethoxyphosphoryloxy)-3h-benzo[d][1,2,3]triazin-4-one; DEPBT. Grades: 95 %. CAS No. 165534-43-0. Molecular formula: C11H14N3O5P. Mole weight: 299.22.
3'-Dithiol Serinol CPG
3'-Dithiol Serinol CPG, an essential chemical for solid-phase peptidesynthesis, is a promising solution to the challenge of preparing disulfide-rich peptides and proteins with higher efficiency. By facilitating the construction of polypeptide chains, this chemical helps to unravel the intricate mechanisms underlying disorders including heart disease, cancer, and Alzheimer's disease at the molecular level, paving the way for targeted intervention and therapy. Synonyms: 3-Dimethoxytrityloxy-2-(3-((R)-α-lipoamido)propanamido)propyl-1-O-succinyl-long chain alkylamino-CPG. Mole weight: 412.46.
PyAOP is a phosphonium salt used as a coupling reagent in Solid-phase peptidesynthesis, without undergoing side reactions with the amino terminus. PyAOP is a derivative of HOAt. Synonyms: PyAOP; (7-AZABENZOTRIAZOL-1-YLOXY)TRIPYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE; 7-AZABENZOTRIAZOL-1-YLOXY-TRIS-(PYRROLIDINO)PHOSPHONIUM HEXAFLUOROPHOSPHATE; (7-AZABENZOTRIAZOLE-1-YLOXY)TRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE; PYAOP; ((3H-[1,2,3]Triazolo[4,5-b]pyridin-3-yl)oxy)tri(pyrrolidin-1-yl)phosphonium hexafluorophosphate; (7-Azabenzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate; (T-4)?-[3-(hydroxy-κO)?-3H-1,?2,?3-triazolo[4,?5-b]?pyridinato]?tri-1-pyrrolidinyl-Phosphorus(1+)? hexafluorophosphate(?1-); tri-1-pyrrolidinyl(3H-1,2,3-triazolo[4,5-b]pyridin-3-yloxy)-Phosphonium hexafluorophosphate(1-). Grades: 98%. CAS No. 156311-83-0. Molecular formula: C17H27N7OP?PF6. Mole weight: 521.38.
3-m-Tolylpropanoic Acid
3-m-Tolylpropanoic Acid is used in the synthesis of piperidine antagonists as CCR1-selective inhibitors. via parallel synthesis. Also used in the synthesis of small molecule antagonists of vasoactive intestinal. peptide receptor1 (VIPR1). Group: Biochemicals. Alternative Names: Hydrocinnamic acid, m-methyl-(7CI,8CI); 3-(3-Methylphenyl)propanoic acid; 3-(3-Methylphenyl)propionic Acid; 3-Methyl- β-phenylpropionic Acid; 3-Methylbenzenepropanoic Acid; 3-Methylhydrocinnamic Acid; 3-m-Tolylpropionic Acid; m-Methylhydrocinnamic Acid. Grades: Highly Purified. CAS No. 3751-48-2. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
3-[(tert-Butoxy)carbonyl]-5-methylbenzoic acid
3-[(tert-Butoxy)carbonyl]-5-methylbenzoic acid is commonly used as a protecting group in peptidesynthesis. Group: Organic frame monomer block. CAS No. 1909308-82-2. Molecular formula: C13H16O4. Mole weight: 236.267 g/mol. Purity: 0.95. IUPACName: 3-methyl-5-[(2-methylpropan-2-yl)oxycarbonyl]benzoic acid. Canonical SMILES: CC1=CC(=CC(=C1)C(=O)OC(C)(C)C)C(=O)O. Catalog: ACM1909308822.
A photoreactive amino acid which can easily be incorporated into a peptide by solid-phase synthesis. Group: Biochemicals. Alternative Names: D,L-BPA. Grades: Highly Purified. Pack Sizes: 20mg. US Biological Life Sciences.