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| Product | Description | |
|---|---|---|
| Pf 184 | Pf 184. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PF 184, NCGC00263213-01, FT-0673646, 1187460-81-6, 8-[[[5-Chloro-2-[3,4-dimethyl-3,4-bis(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxamide. Product Category: Heterocyclic Organic Compound. CAS No. 1187460-81-6. Molecular formula: C32H32ClFN6O4. Mole weight: C32H32ClFN6O4. Purity: >98 %. IUPACName: 8-[[2-[(3S,4R)-3,4-bis(hydroxymethyl)-3,4-dimethylpyrrolidin-1-yl]-5-chloropyridine-4-carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydrobenzo[g]indazole-3-carboxamide. Canonical SMILES: CC1(CN(CC1(C)CO)C2=NC=C(C(=C2)C(=O)NC3=CC4=C(CCC5=C4N(N=C5C(=O)N)C6=CC=C(C=C6)F)C=C3)Cl)CO. Product ID: ACM1187460816. Alfa Chemistry ISO 9001:2015 Certified. Categories: PF-184563. |  |
| PF 184 | PF 184 is a potent and selective IKK-2 inhibitor (IC50 = 37 nM). Displays selectivity over 85 other kinases. Inhibits IL-1 β-induced TNF-α in a steroid-insensitive in vitro model of oxidative stress. Group: Biochemicals. Alternative Names: 8- [ [ [5-Chloro-2- [3, 4-dimethyl-3, 4-bis (hydroxymethyl) -1-pyrrolidinyl] -4-pyridinyl] carbonyl] amino] -1- (4-fluorophenyl) -4, 5-dihydro-1H-benz [g] indazole-3-carboxamide. Grades: Highly Purified. CAS No. 1187460-81-6. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| PF 184 | PF 184 is a potent and selective IKKβ inhibitor (IC50 = 37 nM) with selectivity over 85 other kinases, demonstrating target-specific anti-inflammatory activities in cellular assays and following oral and local delivery in an in vivo model of airway inflammation. Synonyms: 8-[[[5-Chloro-2-[3,4-dimethyl-3,4-bis(hydroxymethyl)-1-pyrrolidinyl]-4-pyridinyl]carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydro-1H-benz[g]indazole-3-carboxamide; PF-184; PF184; PF 184. Grades: ≥98% by HPLC. CAS No. 1187460-81-6. Molecular formula: C32H32ClFN6O4. Mole weight: 619.09. |  |
| ALC-0159 | ALC-0159 is a PEG/lipid conjugate (i.e. PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a PEG chain mass of about 2 kilodaltons (corresponding to about 45-46 ethylene oxide units per molecule of N,N-dimyristyl hydroxyacetamide). It is a non-ionic surfactant by its nature. It has been deployed in the Pfizer-BioNTech SARS-CoV-2 mRNA vaccine that contains the active ingredient tozinameran. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ALC-0159; ALC 0159; ALC0159. Product Category: Others. Appearance: Solid. CAS No. 1849616-42-7. Molecular formula: (C2H4O)nC31H63NO2. Mole weight: 2450. Purity: >95%. IUPACName: 2-[(polyethylene glycol)-2000]-N,N-ditetradecylacetamide. Canonical SMILES: CCCCCCCCCCCCCCN(CCCCCCCCCCCCCC)C(COCCOC)=O. Product ID: ACM1849616427-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Andrastin D | It is produced by the strain of Penicillum sp. FO-3929. It can inhibit PFTase. IC50 is 25.7 μmol/L. Synonyms: CHEBI:142874; methyl (5beta,8alpha,9beta,10alpha,13alpha)-15-hydroxy-4,4,8,12,16-pentamethyl-3,17-dioxoandrosta-11,15-diene-14-carboxylate; methyl 15-hydroxy-4,4,8alpha,12,16-pentamethyl-3,17-dioxo-5beta,9beta,10alpha,13alpha-androsta-11,15-diene-14-carboxylate. CAS No. 184432-08-4. Molecular formula: C26H37O5. Mole weight: 429.57. | |
| Fuberidazole | Fuberidazole. Group: Biochemicals. Alternative Names: 2-(2-Furanyl)-1H-benzimidazole; 2-(2-Furanyl)benzimidazole; 2-(2-Furyl)benzimidazole; 2-(2'-Furyl)benzimidazole; 2-(Furan-2-yl)benzimidazole; B 33172; BAY 33172; Bayer 33172; Fuberidazol; Furidazol; Furidazole; NSC 72670; PF 7402; Voronit; 2-(2-Furyl)-benzimidazole; 2-(2-Furanyl)-1H-benzimidazole. Grades: Highly Purified. CAS No. 3878-19-1. Pack Sizes: 500mg. Molecular Formula: C11H8N2O, Molecular Weight: 184.19. US Biological Life Sciences. | Worldwide |
| Pentafluorophenol | Intermediate of medicine, pesticide and liquid crystal material; used for the preparation of pentafluorophenyl esters for peptide synthesis. Synonyms: PENTAFLUOROPHENOL; UNII-A2YCF0YUHA; MFCD00002156; A2YCF0YUHA; pentafluoro-pheno; PFP; PFP-OH; 2,3,4,5,6-pentafluoro-phenol; Phenol, pentafluoro-; pentafluoro-phenol. Grades: ≥ 99.5% (GC). CAS No. 771-61-9. Molecular formula: C6HF5O. Mole weight: 184.06. | |
| PF-06821497 | PF-06821497. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1-one. CAS No. 1844849-10-0. Molecular formula: C22H24Cl2N2O5. Mole weight: 467.34. Purity: 0.98. Product ID: ACM1844849100. Alfa Chemistry ISO 9001:2015 Certified. | |
| PF-06835919 | PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been implicated in hepatic steatosis, dyslipidemia, obesity, and insulin resistance in humans. Since ketohexokinase (KHK) is the principal enzyme responsible for fructose metabolism, identification of a selective KHK inhibitor may help to further elucidate the effect of KHK inhibition on these metabolic disorders. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PF-06835919; PF 06835919; PF06835919; MDK1846; MDK-1846; MDK 1846; ketohexokinase inhibitor; ketohexokinase-In-1. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2102501-84-6. Molecular formula: C16H19F3N4O2. Mole weight: 356.35. Purity: >98%. IUPACName: 2-((1R,5S,6R)-3-(2-((S)-2-methylazetidin-1-yl)-6-(trifluoromethyl)pyrimidin-4-yl)-3-azabicyclo[3.1.0]hexan-6-yl)acetic acid. Canonical SMILES: O=C(C[C@@H]1[C@]2(CN(C[C@@]12[H])C3=NC(N4[C@H](CC4)C)=NC(C(F)(F)F)=C3)[H])O. Product ID: ACM2102501846. Alfa Chemistry ISO 9001:2015 Certified. Categories: Ketohexokinase inhibitor 1. | |
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