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PF-06873600 Ebvaciclib, also known as PF-06873600, is an orally bioavailable, cyclin-dependent kinase (CDK) inhibitor, with potential antineoplastic activity. Upon administration, PF-06873600 selectively targets, binds to and inhibits the activity of CDKs. Inhibition of these kinases leads to cell cycle arrest, induction of apoptosis and inhibition of tumor cell proliferation. CDKs, ATP-dependent serine/threonine kinases that are important regulators of cell cycle progression and cellular proliferation, are frequently overexpressed in tumor cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ebvaciclib; PF-06873600; PF 06873600; PF06873600. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2185857-97-8. Molecular formula: C20H27F2N5O4S. Mole weight: 471.52. Purity: >98%. IUPACName: Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[[1-(methylsulfonyl)-4-piperidinyl]amino]-. Canonical SMILES: O=C1C(C(F)F)=CC2=CN=C(NC3CCN(S(=O)(C)=O)CC3)N=C2N1[C@H]4[C@](C)(O)CCC4. Product ID: ACM2185857978. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
PF-06873600 PF-06873600 Inhibitor. Uses: Scientific use. Product Category: T8463. CAS No. 2185857-97-8. TARGETMOL CHEMICALS

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