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Phalloidin, a heptapeptide phallotoxin produced by Amanita phalloides, the death cap mushroom, is an F-actin stabilizing toxin and aids cytoskeletal deorganization in WPMY-1 cells. It decreases dissociation rate constant for actin subunits from filament ends and lowers critical concentration for polymerization. Synonyms: Cyclo[L-alanyl-D-threonyl-L-cysteinyl-(4S)-4-hydroxy-L-prolyl-L-alanyl-2-mercapto-L-tryptophyl-(4R)-4,5-dihydroxy-L-leucyl] Cyclic (3?6)-thioether; 18, 9-(Iminoethaniminoethaniminoethanimin omethano)-17H-pyrrolo [1', 2': 5, 6] [1, 5, 8, 11 ] thiatri azacyclopentadecino [15, 1 4-b] indole Cyclic Peptide Derivative; NSC 523214; NSC-523214; NSC523214. CAS No. 17466-45-4. Molecular formula: C35H48N8O11S. Mole weight: 788.87.
Phalloidin
Phalloidin. Group: Biochemicals. Grades: Purified. CAS No. 17466-45-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Phalloidin
Phalloidin is a mushroom-derived toxin which can be used to label F-actin of the cytoskeleton with fluorochrome [1]. Uses: Scientific research. Group: Peptides. CAS No. 17466-45-4. Pack Sizes: 1 mg. Product ID: HY-P0028.
Phalloidin-Atto 425
suitable for fluorescence, ?95.0% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 430LS
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 488
BioReagent, suitable for fluorescence, ?90% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 490LS
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 514
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 520
suitable for fluorescence. Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 565
suitable for fluorescence, ?80% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 594
suitable for fluorescence, ?90% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 655
suitable for fluorescence, ?95.0% (sum of isomers, HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 665
suitable for fluorescence, ?90% (HPLC). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 700
suitable for fluorescence, ?80.0% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 725
suitable for fluorescence, ?80% (HPCE). Group: Fluorescence/luminescence spectroscopy.
Phalloidin-Atto 740
suitable for fluorescence, BioReagent. Group: Fluorescence/luminescence spectroscopy.
Phalloidin, Fluorescein Isothiocyanate Labeled
peptide from Amanita phalloides. Group: Fluorescence/luminescence spectroscopy.
((R)-4-Hydroxy-4-methyl-Orn(CPM-β-Mpa)7)-Phalloidin is fluorophore-labeled phalloidin. Synonyms: Coumarin-bicyclic(Ala-DThr-Cys-cis-4-hydroxy-Pro-Ala-2-mercapto-Trp-4-hydroxy-5-amino-Leu)(S-3?6); Cyclo (-Ala-D-Thr-Cys-cis-Hyp-Ala-Trp- (4R) -4-hydroxy-4-Me-Orn (3- (3- (N- (4- (7-diethylamino-4-methylcoumarin-3-yl) phenyl) succinimido) sulfanyl) propanoyl) ) (Sulfide bond between Cys and indol-2-yl); Phalloidin, 7-[(4R)-N5-[3-[[1-[4-[7-(diethylamino)-4-methyl-2-oxo-2H-1-benzopyran-3-yl]phenyl]-2,5-dioxo-3-pyrrolidinyl]thio]-1-oxopropyl]-4-hydroxy-4-methyl-L-ornithine]-. Grades: ≥95%. CAS No. 1926163-49-6. Molecular formula: C62H75N11O15S2. Mole weight: 1278.46.
((R)-4-Hydroxy-4-methyl-Orn(TRITC)7)-Phalloidin
((R)-4-Hydroxy-4-methyl-Orn(TRITC)7)-Phalloidin is fluorophore-labeled phalloidin. Synonyms: TRITC-bicyclic(Ala-DThr-Cys-cis-4-hydroxy-Pro-Ala-2-mercapto-Trp-4-hydroxy-5-amino-Leu)(S-3?6); Cyclo(-Ala-D-Thr-Cys-cis-Hyp-Ala-Trp-(4R)-4-hydroxy-4-Me-Orn(TRITC)) (Sulfide bond between Cys and indol-2-yl); Rhodamine phalloidin-TRITC. Grades: ≥95%. CAS No. 1926163-50-9. Molecular formula: C60H70N12O13S2. Mole weight: 1231.40.
Jasplakinolide
Jasplakinolide acts as an actin stabilizing agent that stabilizes actin filaments and promotes actin polymerization. It is also a potent inhibitor of breast and prostrate carcinoma cell proliferation. It potently competes with phalloidin for actin binding and induces actin polymerization by stimulating actin filament nucleation in vitro. It induces polymerization of monomeric actin into amorphous masses and disrupts actin filaments in vivo. It is cell permeable and affects chromosome movement in studies. It has insecticidal, antiproliferative and fungicidal activity. It is useful for investigating cell processes mediated by actin depolymerization and polymerization. Synonyms: NSC 613009; NSC613009; NSC-613009; [2S-[1(S*),2R*,4E,6S*,8R*]]-N-[2-Bromo-N-[N-(8-hydroxy-2,4,6-trimethyl-1-oxo-4-nonenyl)-L-alanyl]-N-methyl-D-tryptophyl]-3-(4-hydroxyphenyl)-β-alanine ρ-Lactone; 1-Oxa-5,8,11-triazacyclononadecane β-alanine deriv.; (+)-Jasplakinolide; Cyclo[(3R)-3-(4-hydroxyphenyl)-β-alanyl-(2S,4E,6R,8S)-8-hydroxy-2,4,6-trimethyl-4-nonenoyl-L-alanyl-2-bromo-N-methyl-D-tryptophyl]. Grades: ≥97% by HPLC. CAS No. 102396-24-7. Molecular formula: C36H45BrN4O6. Mole weight: 709.67.
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