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2-Hydroxy-4-(phenylmethyl)-3-morpholinone is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 2-hydroxy-4-(phenylmethyl)-; Fosaprepitant Impurity 23; 4-Benzyl-2-hydroxy-3-morpholinone; 2-Hydroxy-4-benzylmorpholin-3-one. Grades: 95%. CAS No. 287930-73-8. Molecular formula: C11H13NO3. Mole weight: 207.23.
2-Hydroxy-4-(phenylmethyl)-3-morpholinone
2-Hydroxy-4-(phenylmethyl)-3-morpholinone, is an intermediate used for the synthesis of NK1 Receptor Antagonist Aprepitant (A729800), used as as antiemetic drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 287930-73-8. Pack Sizes: 500mg, 5g. Molecular Formula: C11H13NO3, Molecular Weight: 207.23. US Biological Life Sciences.
Rivaroxaban intermediate. Group: Biochemicals. Alternative Names: 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione. Grades: Highly Purified. CAS No. 446292-08-6. Pack Sizes: 5mg. US Biological Life Sciences.
A diastereomeric byproduct formed during the synthesis of Aprepitant metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 419574-33-7. Pack Sizes: 1mg. US Biological Life Sciences.
(5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is a diastereomeric byproduct in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A diastereomeric byproduct formed during the synthesis of aprepitant metabolites. Synonyms: 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6R)-; Aprepitant M2 Metabolite 5-Epimer. Grades: ≥95%. CAS No. 419574-33-7. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
An active metabolite of Aprepitant. Group: Biochemicals. Alternative Names: Aprepitant-M3 Metabolite. Grades: Highly Purified. CAS No. 419574-04-2. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of Esreboxetine. Esreboxetine is a selective norepinephrine reuptake inhibitor for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. Synonyms: 6-[(2-ethoxyphenoxy)?phenylmethyl]?- 3-Morpholinone. Grades: > 95%. CAS No. 93886-32-9. Molecular formula: C19H21NO4. Mole weight: 327.38.
Aprepitant-M3 Metabolite
Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grades: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33.
Fosaprepitant Impurity 3
A metabolite of Aprepitant. Synonyms: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone. Grades: > 95%. CAS No. 287930-75-0. Molecular formula: C21H19F6NO3. Mole weight: 447.38.
An impurity of Rivaroxaban.Metabolite.Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 11; SCHEMBL455793; DTXSID90623242; DEXXSYVEWAYIGZ-UHFFFAOYSA-N; BCP14166; BCP34183; LS-14306; FT-0661929; 4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one; 4-{4-[5-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL}MORPHOLIN-3-ONE; 4-{4-[5-(aminomethyl)-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morpholine-3-one; racemic 4-[4-[5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one; 4-{4-[(5S)-5-aminomethyl)-2-oxo-1,3-oxazolidin-3-yl}morpholin-3-on; 4-[4-[(5S)-5-(AMinoMethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone; Rivaroxaban Amine Impurity; (R)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one. Grades: > 95%. Molecular formula: C14H17N3O4. Mole weight: 291.31.
An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 4-[4-[[(2S)-3-Amino-2-hydroxypropyl]amino]phenyl]-3-morpholinone; Rivaroxaban Impurity 20; Rivaroxaban Impurity 41. Grades: 98% by HPLC. CAS No. 1403383-56-1. Molecular formula: C13H19N3O3. Mole weight: 265.31.
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