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2-Hydroxy-4-(phenylmethyl)-3-morpholinone 2-Hydroxy-4-(phenylmethyl)-3-morpholinone is an intermediate of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 2-hydroxy-4-(phenylmethyl)-; Fosaprepitant Impurity 23; 4-Benzyl-2-hydroxy-3-morpholinone; 2-Hydroxy-4-benzylmorpholin-3-one. Grades: 95%. CAS No. 287930-73-8. Molecular formula: C11H13NO3. Mole weight: 207.23. BOC Sciences 8
2-Hydroxy-4-(phenylmethyl)-3-morpholinone 2-Hydroxy-4-(phenylmethyl)-3-morpholinone, is an intermediate used for the synthesis of NK1 Receptor Antagonist Aprepitant (A729800), used as as antiemetic drugs. Group: Biochemicals. Grades: Highly Purified. CAS No. 287930-73-8. Pack Sizes: 500mg, 5g. Molecular Formula: C11H13NO3, Molecular Weight: 207.23. US Biological Life Sciences. USBiological 10
Worldwide
(2R) -2-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-4- (phenylmethyl) -3-morpholinone (2R) -2-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-4- (phenylmethyl) -3-morpholinone, is the key 3- (4-Fluorophenyl) morpholine moiety used in the synthesis of NK1 receptor antagonist Aprepitant (A729800). Group: Biochemicals. Grades: Highly Purified. CAS No. 287930-75-0. Pack Sizes: 25mg, 250mg. Molecular Formula: C21H19F6NO3, Molecular Weight: 447.37. US Biological Life Sciences. USBiological 10
Worldwide
(3S)-3-(4-Fluorophenyl)-4-(phenylmethyl)-2-morpholinone (3S)-3-(4-Fluorophenyl)-4-(phenylmethyl)-2-morpholinone. Group: Biochemicals. Alternative Names: N-Benzyl-(3S)-3-(4-fluorophenyl)morpholin-2-one. Grades: Highly Purified. CAS No. 159706-87-3. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C17H16FNO2. US Biological Life Sciences. USBiological 7
Worldwide
4-[ ( (2R) -Hydroxy-3-phthalimido) propylamine]phenyl-3-morpholinone Rivaroxaban intermediate. Group: Biochemicals. Alternative Names: 2-[ (2R) -2-Hydroxy-3-[[4- (3-oxo-4-morpholinyl) phenyl]amino]propyl]-1H-isoindole-1, 3 (2H) -dione. Grades: Highly Purified. CAS No. 446292-07-5. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
4-[ ( (2R) -Hydroxy-3-phthalimido) propylamine]phenyl-3-morpholinone-d4 Labeled Rivaroxaban intermediate. Group: Biochemicals. Alternative Names: 2-[ (2R) -2-Hydroxy-3-[[4- (3-oxo-4-morpholinyl) phenyl]amino]propyl]-1H-isoindole-1, 3 (2H) -dione-d4. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Rivaroxaban intermediate. Group: Biochemicals. Alternative Names: Des(5-chloro-2-carboxythienyl) Rivaroxaban. Grades: Highly Purified. CAS No. 446292-10-0. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
4-[4-[(5S)-5-(Aminomethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4 Labeled Rivaroxaban intermediate. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone Rivaroxaban intermediate. Group: Biochemicals. Alternative Names: 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione. Grades: Highly Purified. CAS No. 446292-08-6. Pack Sizes: 5mg. US Biological Life Sciences. USBiological 2
Worldwide
4-[4-[(5S)-5-Phthalimidomethyl-2-oxo-3-oxazolidinyl]phenyl]-3-morpholinone-d4 Labeled Rivaroxaban intermediate. Group: Biochemicals. Alternative Names: 2-[[(5S)-2-Oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-1H-isoindole-1,3(2H)-dione-d4. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
(5R, 6R) -6-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-5- (4-fluorophenyl) -3-morpholinone A diastereomeric byproduct formed during the synthesis of Aprepitant metabolites. Group: Biochemicals. Grades: Highly Purified. CAS No. 419574-33-7. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
(5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone (5R,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is a diastereomeric byproduct in the preparation of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: A diastereomeric byproduct formed during the synthesis of aprepitant metabolites. Synonyms: 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6R)-; Aprepitant M2 Metabolite 5-Epimer. Grades: ≥95%. CAS No. 419574-33-7. Molecular formula: C20H16F7NO3. Mole weight: 451.33. BOC Sciences 8
(5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone (5R,6S)-6-[(1S)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone is an active metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Synonyms: 3-Morpholinone, 6-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5R,6S)-; ent-Aprepitant-M3; Aprepitant M3 Metabolite (1S,5R,6S)-Isomer. Molecular formula: C20H16F7NO3. Mole weight: 451.33. BOC Sciences 8
(5S, 6R) -6- [ (1R) -1- [3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-5- (4-fluorophenyl) -3-morpholinone [aprepitant-M3] (5S, 6R) -6- [ (1R) -1- [3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-5- (4-fluorophenyl) -3-morpholinone [aprepitant-M3]. Group: Biochemicals. Alternative Names: Aprepitant-M3 metabolite. Grades: Highly Purified. CAS No. 419574-04-2. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C20H16F7NO3. US Biological Life Sciences. USBiological 6
Worldwide
(5S, 6R) -6-[ (1R) -1-[3, 5-Bis (trifluoromethyl) phenyl]ethoxy]-5- (4-fluorophenyl) -3-morpholinone. [Aprepitant-M3] An active metabolite of Aprepitant. Group: Biochemicals. Alternative Names: Aprepitant-M3 Metabolite. Grades: Highly Purified. CAS No. 419574-04-2. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
6-(4-Fluorophenyl)-3-morpholinone Synonyms: 6-(4-Fluoro-phenyl)-morpholin-3-one; 3-Morpholinone, 6-(4-fluorophenyl)-. Grades: ≥95%. CAS No. 951626-54-3. Molecular formula: C10H10FNO2. Mole weight: 195.19. BOC Sciences 8
3-Morpholine Metabolite A metabolite of Esreboxetine. Esreboxetine is a selective norepinephrine reuptake inhibitor for the treatment of neuropathic pain and fibromyalgia but failed to show significant benefit over currently available medications and was discontinued. Synonyms: 6-[(2-ethoxyphenoxy)?phenylmethyl]?- 3-Morpholinone. Grades: > 95%. CAS No. 93886-32-9. Molecular formula: C19H21NO4. Mole weight: 327.38. BOC Sciences 8
Aprepitant-M3 Metabolite Aprepitant-M3 Metabolite is a metabolite of Aprepitant, a novel selective neurokinin-1 (NK-1) receptor antagonist. Uses: An active metabolite of aprepitant. Synonyms: (5S,6R)-6-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-3-morpholinone; Aprepitant-M3; 3-Morpholinone, 6-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-5-(4-fluorophenyl)-, (5S,6R)-. Grades: ≥95%. CAS No. 419574-04-2. Molecular formula: C20H16F7NO3. Mole weight: 451.33. BOC Sciences
Fosaprepitant Impurity 3 A metabolite of Aprepitant. Synonyms: (2R)-2-[(1R)-1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-(phenylmethyl)-3-morpholinone. Grades: > 95%. CAS No. 287930-75-0. Molecular formula: C21H19F6NO3. Mole weight: 447.38. BOC Sciences 7
rel- (2R, 3R) -6-[a- (2-ethoxyphenoxy) benzyl]morpholin-3-one rel- (2R, 3R) -6-[a- (2-ethoxyphenoxy) benzyl]morpholin-3-one. Group: Biochemicals. Alternative Names: (6R) -rel-6-[ (R) - (2-ethoxyphenoxy) phenylmethyl]-3-morpholinone; (R*, R*) - (+/-) -6-[ (R) - (2-Ethoxyphenoxy) phenylmethyl]-3-morpholinone; 6-[ (2-Ethoxyphenoxy) phenylmethyl]-3-morpholinone. Grades: Highly Purified. CAS No. 98769-79-0. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C19H21NO4. US Biological Life Sciences. USBiological 8
Worldwide
Rivaroxaban Impurity 11 An impurity of Rivaroxaban.Metabolite.Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: Rivaroxaban Impurity 11; SCHEMBL455793; DTXSID90623242; DEXXSYVEWAYIGZ-UHFFFAOYSA-N; BCP14166; BCP34183; LS-14306; FT-0661929; 4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one; 4-{4-[5-(AMINOMETHYL)-2-OXO-1,3-OXAZOLIDIN-3-YL]PHENYL}MORPHOLIN-3-ONE; 4-{4-[5-(aminomethyl)-2-oxo-1,3-oxazolidine-3-yl]-phenyl}-morpholine-3-one; racemic 4-[4-[5-(aminomethyl)-2-oxo-1,3-oxazolidin-3-yl]phenyl]morpholine-3-one; 4-{4-[(5S)-5-aminomethyl)-2-oxo-1,3-oxazolidin-3-yl}morpholin-3-on; 4-[4-[(5S)-5-(AMinoMethyl)-2-oxo-3-oxazolidinyl]phenyl]-3-Morpholinone; Rivaroxaban Amine Impurity; (R)-4-(4-(5-(Aminomethyl)-2-oxooxazolidin-3-yl)phenyl)morpholin-3-one. Grades: > 95%. Molecular formula: C14H17N3O4. Mole weight: 291.31. BOC Sciences 6
(S)-4-(4-((3-amino-2-hydroxypropyl)amino)phenyl)morpholin-3-one An impurity of Rivaroxaban. Rivaroxaban inhibits both free Factor Xa and Factor Xa bound in the prothrombinase complex. It is a highly selective direct Factor Xa inhibitor with oral bioavailability and rapid onset of action. Synonyms: 4-[4-[[(2S)-3-Amino-2-hydroxypropyl]amino]phenyl]-3-morpholinone; Rivaroxaban Impurity 20; Rivaroxaban Impurity 41. Grades: 98% by HPLC. CAS No. 1403383-56-1. Molecular formula: C13H19N3O3. Mole weight: 265.31. BOC Sciences 8

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