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It has a role as an alpha-adrenergic agonist, a cardiotonic drug, a mydriatic agent, a protective agent, a vasoconstrictor agent, a sympathomimetic agent and a nasal decongestant. Alternative Names: L-Phenylephrine. Metasynephrine. m-Oxedrine. CAS No. 59-42-7. Product ID: API59427. Molecular formula: C9H13NO2. Mole weight: 167.2. EINECS: 200-424-8. SMILES: CNC[C@@H](C1=CC(=CC=C1)O)O. Appearance: Crystalline Solid. Category: Antishock Vasoactive APIs.
Phenylephrine
Phenylephrine. Uses: For analytical and research use. Group: Api standards; european pharmacopoeia (ph. eur.); pharmaceutical toxicology; pharmacopoeial standards. Alternative Names: Phenylephrine, (1R)-1-(3-Hydroxyphenyl)-2-(methylamino)ethanol. CAS No. 59-42-7. IUPAC Name: 3-[(1R)-1-hydroxy-2-(methylamino)ethyl]phenol. Molecular formula: C9H13NO2. Mole weight: 167.20. Catalog: APS59427. SMILES: CNC[C@H](O)c1cccc(O)c1. Format: Neat.
Phenylephrine
(R)-(-)-Phenylephrine is a selective α 1 -adrenoceptor agonist primarily used as a decongestant. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-(-)-Phenylephrine; L-Phenylephrine. CAS No. 59-42-7. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B0769.
Phenylephrine bitartrate
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Phenylephrine HCl
Phenylephrine HCl is a selective α1-adrenergic receptor agonist. CAS No. 61-76-7. Product ID: API61767. Molecular formula: C9H13NO2·HCl. Mole weight: 203.67. SMILES: CNC[C@@H](C1=CC(=CC=C1)O)O.Cl. Standard: USP/EP. Category: Active Pharmaceutical Ingredients.
Phenylephrine HCL USP
Phenylephrine HCL USP.
CA, FL & NJ
Phenylephrine hydrochloride
(R)-(-)-Phenylephrine hydrochloride is a selective α 1 -adrenoceptor agonist with pK i s of 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively. Uses: Scientific research. Group: Natural products. Alternative Names: (R)-(-)-Phenylephrine hydrochloride; L-Phenylephrine hydrochloride. CAS No. 61-76-7. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg. Product ID: HY-B0471.
Phenylephrine Hydrochloride
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardsapi standardsbritish pharmacopoeiaeuropean pharmacopoeia (ph. eur.)impurity standardspharmaceutical toxicologypharmacopoeial standards. Alternative Names: Etilefrine Hydrochloride Imp. B (EP) as R-Enantiomer Hydrochloride, Benzenemethanol, 3-hydroxy-alpha-[(methylamino)methyl]-, hydrochloride, (R)-, M-Sympatol, Etilefrine Imp. B (EP), Decadron, Lexatol, Benzenemethanol, 3-hydroxy-alpha-[(methylamino)methyl]-, hydrochloride (1:1), (alphaR)-, l-Phenylephrine hydrochloride, Isophrin, Meta-Synephrine hydrochloride, (R)-Phenylephrine hydrochloride, Neo-S.
Phenylephrine Impurity 21
Phenylephrine Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1242184-39-9. Molecular formula: C9H13NO5S. Mole weight: 247.27. Catalog: APB1242184399.
Phenylephrine Related Compound D
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Phenylephrine Related Compound F
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Phenylephrine Related Compound G
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Intermediate in the preparation of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
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N-(2-Succinyl)phenylephrine(mixture of diastereomers)
N-(2-Succinyl)phenylephrine(mixture of diastereomers). Uses: Designed for use in research and industrial production. Additional or Alternative Names: N-[(2R)-2-Hydroxy-2-(3-hydroxyphenyl)ethyl]-N-methylaspartic Acid. Product Category: Heterocyclic Organic Compound. CAS No. 915278-80-7. Molecular formula: C13H17NO6. Mole weight: 283.28. Product ID: ACM915278807. Alfa Chemistry ISO 9001:2015 Certified.
(±)-Phenylephrine-d3 hydrochloride solution
100 ?g/mL in methanol with 5% 1 M HCl (as free base), ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
(-)-Phenylephrine hydrogentartrate
(-)-Phenylephrine hydrogentartrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 17162-39-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C9H13NO2·C4H6O6. US Biological Life Sciences.
Impurity D of Phenylephrine. Group: Biochemicals. Alternative Names: 3-Hydroxy-α - [ [methyl (phenylmethyl) amino] methyl] benzenemethanol. Grades: Highly Purified. CAS No. 1159977-09-9. Pack Sizes: 10mg. US Biological Life Sciences.
rac Benzyl Phenylephrine (Phenylephrine Impurity D). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-Hydroxy-?-[[methyl(phenylmethyl)amino]methyl]benzenemethanol,Phenylephrine Impurity D. CAS No. 1159977-09-9. Pack Sizes: 10MG. IUPAC Name: 3-[2-[benzyl(methyl)amino]-1-hydroxy-ethyl]phenol. Molecular formula: C16H19NO2. Mole weight: 257.33. Catalog: APS1159977099. SMILES: CN(CC(O)c1cccc(O)c1)Cc2ccccc2. Format: Neat. Shipping: Room Temperature.
rac norphenylephrine hydrochloride (phenylephrine impurity A)
rac norphenylephrine hydrochloride (phenylephrine impurity A). Group: Biochemicals. Alternative Names: a- (Aminomethyl) -3-hydroxy Benzene methanol. Grades: Highly Purified. CAS No. 4779-94-6. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C8H12ClNO2. US Biological Life Sciences.
Worldwide
rac Norphenylephrine Hydrochloride (Phenylephrine Impurity A)
Impurity A of phenylephrine. A phenylephrine derivative as leukotriene D4 antagonists. Group: Biochemicals. Alternative Names: α - (Aminomethyl) -3-hydroxy Benzene methanol. Grades: Highly Purified. CAS No. 4779-94-6. Pack Sizes: 10mg. US Biological Life Sciences.
(R) -O, O-Bis (tert-butyldimethlsilyl) phenylephrine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
(R)-Phenylephrine-[d3]
(R)-Phenylephrine-[d3] is an isotope labelled (R)-Phenylephrine, which is an α1-adrenoceptor agonist. Synonyms: (R)-Phenylephrine-d3. Grade: 95%. CAS No. 88694-06-8. Molecular formula: C9H10D3NO2. Mole weight: 170.22.
(R)-(-)-Phenylephrine-[d3] Hydrochloride
(R)-(-)-Phenylephrine-[d3] Hydrochloride is the labelled salt of Phenylephrine, which is a selective α1-adrenergic receptor agonist of the phenethylamine class. Synonyms: (R)-(-)-Phenylephrine D3 Hydrochloride; (R)-(-)-Phenylephrine-2,4,6-d3 HCl; Phenylephrine D3 hydrochloride; 3-[(1R)-1-hydroxy-2-(methylamino)ethyl](2,4,6-D3)phenol hydrchloride; (αR)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol-d3 Hydrochloride; (-)-m-Hydroxy-α-[(methylamino)methyl]benzyl Alcohol-d3 Hydrochloride. Grade: >95%. CAS No. 1276197-50-2. Molecular formula: C9H11D3ClNO2. Mole weight: 206.68.
Phenylephrine HCl is a selective α1-adrenergic receptor agonist of the phenethylamine class used primarily as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. Grade: >98%. CAS No. 61-76-7. Molecular formula: C9H14ClNO2. Mole weight: 203.67.
R-(-)-Phenylephrine hydrochloride solution
1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material. Group: Certified reference materials (crms).
(R)-Phenylephrine-L-tartaramide (>90%)
(R)-Phenylephrine-L-tartaramide (>90%). Uses: For analytical and research use. Group: Impurity standards. Catalog: APS00109. Format: Neat.
(R/S)-Phenylephrine-d3 Glucuronide
A deuterated labelled of Phenylephrine glucuronide which is a metabolite of Phenylephrine, a selective α1-adrenergic receptor agonist of the phenethylamine class. Grade: 95% by HPLC; 98% atom D. Molecular formula: C15H18D3NO8. Mole weight: 346.35.
(R/S)-Phenylephrine-d3 HCl
An impurity of Phenylephrine which is a powerful vasoconstrictor and works by reducing swelling of the blood vessels in the nasal passages. Grade: 95% by HPLC; 98% atom D. Molecular formula: C9H10D3NO2.HCl. Mole weight: 206.68.
(S)-Phenylephrine-d3 Hydrochloride
An impurity of Phenylephrine which is a decongestant that shrinks blood vessels in the nasal passages. Synonyms: (αS)-3-Hydroxy-α-[(methylamino)methyl]benzenemethanol-d3 Hydrochloride (1:1); (+)-m-Hydroxy-α-[(methylamino)methyl]-benzyl Alcohol-d3; (+)-Phenylephrine-d3 Hydrochloride. Grade: > 95%. Molecular formula: C9H10NO2D3·HCl. Mole weight: 206.69.
An impurity of Phenylephrine which is an oral selective α1-adrenergic receptor agonist. Synonyms: 939-38-8; (+)-Phenylephrine hydrochloride; (S)-Phenylephrine Hydrochloride; UNII-95T627AGR395T627AGR3. Grade: > 95%. CAS No. 939-38-8. Molecular formula: C9H13NO2.HCl. Mole weight: 203.67.
(S)-Phenylephrine Hydrochloride
(S)-Phenylephrine Hydrochloride, is an isomer of (R)-Phenylephrine Hydrochloride. It is a selective α1-adrenergic receptor agonist used mainly as a decongestant, as an agent to dilate the pupil, and to increase blood pressure. Group: Biochemicals. Alternative Names: (α S) -3-Hydroxy-α -[ (methylamino) methyl]benzenemethanol Hydrochloride (1:1); (+)-m-Hydroxy-α-[(methylamino)methyl]-benzyl Alcohol; (+)-Phenylephrine Hydrochloride. Grades: Highly Purified. CAS No. 939-38-8. Pack Sizes: 250mg, 500mg, 1g. US Biological Life Sciences.
1,2,3,4-Tetrahydro-2-methyl-4,8-isoquinolinediol Hydrochloride is an product formed during the decomposition of Phenylephrine. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg, 100mg. Molecular Formula: C10H14ClNO2. US Biological Life Sciences.
Product formed during the decomposition of Phenylephrine. Synonyms: 1,2,3,4-Tetrahydro-2-methyl-4,6-isoquinolinediol. Grade: > 95%. CAS No. 23824-24-0. Molecular formula: C10H13NO2. Mole weight: 179.22.
An impurity of Phenylephrine. Phenylephrine is a selective alpha-1 adrenergic receptor agonist used primarily as a decongestant to relieve nasal and sinus congestion caused by colds, allergies, or sinusitis. Synonyms: Phenylephrine Isoquinolinone Analog; Phenylephrine Isoquinolinone; 1-(3-Hydroxybenzoyl)-2-methyl-6(2H)-isoquinolinone. Grade: ≥95%. CAS No. 2990371-07-6. Molecular formula: C17H13NO3. Mole weight: 279.29.
1-(3-Hydroxybenzyl)-2-methylisoquinolin-6(2H)-one
1-(3-Hydroxybenzyl)-2-methylisoquinolin-6(2H)-one is an impurity of Phenylephrine (P320640), an α-Adrenergic agonist. Mydriatic; decongestant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C17H13NO3, Molecular Weight: 279.29. US Biological Life Sciences.
1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1312706-19-6. Pack Sizes: 25mg, 50mg. Molecular Formula: C15H17NO4. US Biological Life Sciences.
1-[5-(Hydroxymethyl)-2-furyl]-2-methyl-1,2,3,4-tetrahydroisochinolin-4,8-diol is a degradation product of phenylephrine during the synthesis of the anti-cold medicine. Group: Biochemicals. Grades: Highly Purified. CAS No. 1312706-18-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C15H17NO4. US Biological Life Sciences.
Worldwide
2,2-Dimethyl-5-oxo-1,3-dioxolane-4-acetic Acid
2,2-Dimethyl-5-oxo-1,3-dioxolane-4-acetic Acid is a reagent used to synthesize degradation products of Phenylephrine (P320635 Hydrochloride salt) in over-the-counter products. Group: Biochemicals. Grades: Highly Purified. CAS No. 114458-03-6. Pack Sizes: 2.5g, 25g. Molecular Formula: C7H10O5, Molecular Weight: 174.15. US Biological Life Sciences.
2,2-Dimethyl-5-oxo-1,3-dioxolane-4-acetic Acid Phenylmethyl Ester is an potential degradation product of phenylephrine in over the counter products. Group: Biochemicals. Grades: Highly Purified. CAS No. 1049703-02-7. Pack Sizes: 50mg, 500mg. Molecular Formula: C14H16O5. US Biological Life Sciences.
Worldwide
2, 2'- (Methylazanediyl) bis (1- (3-hydroxyphenyl) ethanone) Hydrochloride
2, 2'- (Methylazanediyl) bis (1- (3-hydroxyphenyl) ethanone) Hydrochloride is an impurity formed in the synthesis of Phenylephrine (P320635), a selective α1-adrenergic receptor agonist used as a decongestant. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C17H18ClNO4. US Biological Life Sciences.
Intermediate in the preparation of an analogue of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Intermediate in the preparation of an analogue of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Intermediate in the preparation of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Intermediate in the preparation of 6-Bromo Phenylephrine an analogue of the α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
2-Chloro-5-hydroxybenzaldehyde
2-Chloro-5-hydroxybenzaldehyde is used as a reagent in the synthesis of p38 inhibitors which are used for the treatment of chronic obstructive pulmonary disease. It is also used in the preparation of halogenated analogs of L-meta-tyrosine which is a biodegradable herbicide. 2-Chloro-5-hydroxybenzaldehyde may also be used as a starting material in the synthesis of chlorinated phenylephrine. Group: Biochemicals. Grades: Highly Purified. CAS No. 7310-94-3. Pack Sizes: 250mg, 500mg. Molecular Formula: C7H5ClO2, Molecular Weight: 156.57. US Biological Life Sciences.
2-Hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxobutanoic acid is an impurity of Phenylephrine, which is a selective α1-adrenergic receptor agonist used as a nasal decongestant and cardiotonic agent. Synonyms: Phenylephrine Related Compound; (2RS)-Hydroxy-4[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxo-butanoic Acid; Butanoic acid, 2-hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxo-; Phenylephrine Impurity 19 (Mixture of Diastereomers); 2-hydroxy-4-(((R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl)(methyl)amino)-4-oxobutanoic acid. Grade: ≥95%. CAS No. 1217525-08-0. Molecular formula: C13H17NO6. Mole weight: 283.28.
3-Hydroxy-α-[(methylamino)methyl]-(R)-benzenemethanol 1-Acetate Hydrochloride is an impurity in the synthesis of (R)-Phenylephrine (P320640), an α-Adrenergic agonist. Mydriatic; decongestant. Group: Biochemicals. Grades: Highly Purified. CAS No. 58952-79-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C13H18ClNO4, Molecular Weight: 287.74. US Biological Life Sciences.
3-Hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxobutanoic acid is an impurity of Phenylephrine, which is a selective α1-adrenergic receptor agonist used as a nasal decongestant and cardiotonic agent. Synonyms: Butanoic acid, 3-hydroxy-4-[[(2R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl]methylamino]-4-oxo-; 3-hydroxy-4-(((R)-2-hydroxy-2-(3-hydroxyphenyl)ethyl)(methyl)amino)-4-oxobutanoic acid; Phenylephrine Related Compound; Phenylephrine Impurity 31 (Mixture of Diastereomers); N-Methyl-N-[(βR)-β,3-dihydroxyphenethyl]-3-hydroxysuccinamidic acid. Grade: ≥95%. CAS No. 830346-80-0. Molecular formula: C13H17NO6. Mole weight: 283.28.
3-Hydroxymandelic Acid, a metabolite of Phenylephrine , Phenylephrine is a α-receptor agonist. Uses: Scientific research. Group: Natural products. CAS No. 17119-15-2. Pack Sizes: 10 mM * 1 mL; 100 mg. Product ID: HY-W015326.
3-Methyl-5-phenyl-2-oxazolidinone β-D-Glucuronide Triacetate (Mixture of Diastereoisomers)
3-Methyl-5-phenyl-2-oxazolidinone β-D-Glucuronide Triacetate (Mixture of Diastereoisomers) is an intermediate in the synthesis of Phenylephrine β-D-Glucuronide, a metabolite of Phenylephrine, an α-Adrenergic agonist. Synonyms: (2S,3S,4S,5R,6S)-2-(Methoxycarbonyl)-6-(3-(3-methyl-2-oxooxazolidin-5-yl)phenoxy)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C23H27NO12. Mole weight: 509.46.
Intermediate in the preparation of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. CAS No. 1415393-66-6. Pack Sizes: 50mg. US Biological Life Sciences.
Intermediate in the preparation of 6-Bromo Phenylephrine an analogue of the α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences.
Intermediate in the preparation of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Intermediate in the preparation of α-adrenergic agonist, Phenylephrine (P320640). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
5,6-Epoxyeicosatrienoic acid
5,6-Epoxyeicosatrienoic acid (5,6-EET; (±)5,6-EpETrE) is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5,6-Epoxyeicosatrienoic acid degrades into 5,6-DiHET and 5,6-δ-lactone, which can be converted to 5,6-DiHET and quantified by GC-MS. In neuroendocrine cells, such as the anterior pituitary and pancreatic islets, 5,6-Epoxyeicosatrienoic acid has been implicated in the mobilization of calcium and hormone secretion. 5,6-Epoxyeicosatrienoic acid is an inhibitor of T-type voltage-gated calcium channels (Cav3) that inhibits isoforms Cav3.1, Cav3.2 ( IC 50 =0.54 μM), and Cav3. and decreases nifedipine-resistant phenylephrine-induced vasoconstriction in isolated mouse mesenteric arteries via Cav3.2 blockade when used at a concentration of 3 μM. In addition, it is a substrate of COX-1 and COX-2. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5,6-EET; (±)5,6-EpETrE. CAS No. 87173-80-6. Pack Sizes: 25 μg (312.04 μM * 250 μL in Ethanol); 50 μg (312.04 μM * 500 μL in Ethanol); 100 μg (312.04 μM * 1 mL in Ethanol). Product ID: HY-132184.
ABT-866
ABT-866 is a novel alpha-adrenoceptor agent that demonstrates intrinsic activity at the α1A-adrenoceptor subtype present in the rabbit urethra (pD2=6.22, with 80% of the phenylephrine response). Synonyms: N-[3-(1H-imidazol-5-ylmethyl)phenyl]ethanesulfonamide; ABT-866; ABT 866; ABT866; A 286666; A286666; A-286666. Grade: >98%. CAS No. 258526-74-8. Molecular formula: C12H15N3O2S. Mole weight: 265.33.
Adrenochrome
An impurity of Phenylephrine which selectively binds to alpha receptors which cause blood vessels to constrict. Synonyms: Adrenochrome. Grade: > 95%. CAS No. 54-06-8. Molecular formula: C9H9NO3. Mole weight: 179.18.
AdTx1
AdTx1 is a high affinity, selective and non-competitive α1A adrenoceptor antagonist with Ki value of 0.35 nM. It is a 65 amino-acid peptide originally isolated from the venom of the green mamba. It is stabilized by four disulfide bridges and belongs to the family of the three-finger-fold peptide. It displays no significant activity against a range of other GPCRs. It antagonizes effects of phenylephrine on intra-urethral pressure in rats and on isolated rabbit prostate muscle in vitro. It is used as a potent relaxant of smooth muscles. Synonyms: ρ-Da1a. Grade: >98%. Molecular formula: C310H481N87O100S8. Mole weight: 7283.22.
ARC 239
ARC239 dihydrochloride is a potent and selective α2 B adrenoceptor antagonist. It is used as an α-adrenoceptor blocking drug. It competitively antagonizes pressor responses to adrenaline and inhibits pressor responses to noradrenaline, tyramine, phenylephrine and dimethylphenylpiperazinium. Uses: Arc239 dihydrochloride is used as an α-adrenoceptor blocking drug. Synonyms: ARC239 dihydrochloride; ARC 239 dihydrochloride; ARC-239 dihydrochloride; 2-(2-(4-(2-Methoxyphenyl)piperazin-1-yl)ethyl)-4,4-dimethyl-1,3-(2H,4H)-isoquinolindione dihydrochloride; AR-C239 Dihydrochloride. Grade: 98%. CAS No. 67339-62-2. Molecular formula: C24H29N3O3. Mole weight: 407.5.
BIX NHE1 inhibitor
BIX NHE1 inhibitor is a potent and selective NHE1 inhibitor (IC50 = 31 nM). It attenuates ischemic damage in an ischemia reperfusion injury isolated rat heart model ex vivo, attenuates phenylephrine-induced cardiomyocyte hypertrophy in vitro. Synonyms: BI-9627; BI 9627; BI9627; 4-(1-Acetyl-4-piperidinyl)-N-(aminoiminomethyl)-3-(trifluoromethyl)benzamide hydrochloride. Grade: ≥98% by HPLC. CAS No. 1204329-34-9. Molecular formula: C16H19F3N4O2.HCl. Mole weight: 392.8.
Ethyl cinnamate
Ethyl cinnamate, an orally active chemical constituent of the rhizome of Kaempferia galanga , exhibits anti-cancer, nematocidal, sedative and vasorelaxant activities. Ethyl cinnamate is a fragrance ingredient used as a food flavor and additive for cosmetic products. Ethyl cinnamate is also an excellent clearing reagent for mammalian tissues. Ethyl cinnamate suppresses tumor growth through anti-angiogenesis by attenuating VEGFR2 signal pathway in colorectal cancer. Ethyl cinnamate inhibits the tonic contractions induced by high K+ and phenylephrine (PE) with respective IC 50 values of 0.30 mM and 0.38 mM in rat aorta [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 103-36-6. Pack Sizes: 10 mM * 1 mL; 100 g. Product ID: HY-Y0121.
Fmoc-His(3-Me)-OH
Fmoc-His(3-Me)OH derives Histidine-associating compounds with biological activity. Fmoc-His(3-Me)OH, with Fmoc-citrulline-OH, Fmoc-His(1-Me)-OH together, forms tri-peptides and shows vasodilating effect with EC 50 s of 2.7-4.7 mM in 1.0 mM Phenylephrine (PE)-contracted aorta rings. Fmoc-His(3-Me)OH (resin) also makes Methyl-His-Gly-Lys (His(3-Me)-Gly-Lys), thus acts as an [Ca 2+ ] i inhibitor. Fmoc-His(3-Me)OH methylates NAHIS02, making it unable to block the Alzheimer's Aβ channel [1] [2] [3]. Uses: Scientific research. Group: Peptides. CAS No. 252049-16-4. Pack Sizes: 100 mg; 250 mg; 1 g. Product ID: HY-W111226.
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