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| Product | Description | |
|---|---|---|
| Phosphoramidon | Phosphoramide is an inhibitor of pyrolytic enzyme derived from the culture of Streptomyces tanashiensis. Synonyms: N-(alpha-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan. Grades: >98%. CAS No. 119942-99-3. Molecular formula: C23H34N3O10P.xNa. Mole weight: 543.50 (free acid). |  |
| Phosphoramidon | Phosphoramidon. Group: Biochemicals. Grades: Highly Purified. CAS No. 119942-99-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. US Biological Life Sciences. |  Worldwide |
| Phosphoramidon disodium | Phosphoramidon disodium, a microbial metabolite , is a specific metalloprotease thermolysin inhibitor with an IC 50 of 0.4 μg/mL. Phosphoramidon disodium also inhibits endothelin-converting enzyme ( ECE ), neutral endopeptidase ( NEP ), and angiotensin-converting enzyme ( ACE ) with IC 50 values of 3.5, 0.034, and 78 μM, respectively [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 164204-38-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-N2021A. |  |
| Phosphoramidon disodium salt | ?97% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Phosphoramidon Disodium Salt | Phosphoramidon is a powerful inhibitor of thermolysin without inhibiting the other endopeptidases such as trypsin, papain, chymotrypsin. Synonyms: N-(alpha-Rhamno-pyranosyl-phos-phono)-L-leucyl-L-tryptophan disodium salt; L-Tryptophan, N- ( ( (6-deoxy-alpha-L-mannopyranosyl) oxy) hydroxyphosphinyl) -L-leucyl-, disodium salt. Grades: >98%. CAS No. 164204-38-0. Molecular formula: C23H32N3Na2O10P. Mole weight: 587.47. | |
| atrolysin C | A 24 kDa hemorrhagic endopeptidase from the venom of the western diamondback rattlesnake (Crotalus atrox) that digests type IV collagen, and exists as two forms, c and d. Phosphoramidon inhibits in the 0.1 mM range. In peptidase family M12 (astacin family). Hemorrhagic toxin-2 of C. ruber ruber has the same Mr and specificity and is a homologue. Group: Enzymes. Synonyms: Crotalus atrox metalloendopeptidase c; hemorrhagic toxin c and d. Enzyme Commission Number: EC 3.4.24.42. CAS No. 158886-17-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4324; atrolysin C; EC 3.4.24.42; 158886-17-0; Crotalus atrox metalloendopeptidase c; hemorrhagic toxin c and d. Cat No: EXWM-4324. |  |
| bontoxilysin | This zinc enzyme, produced by Clostridium botulinum, occurs as forms A-G that differ in specificity of action on the proteins of the neuroexocytosis apparatus. The 150-kDa proenzymes of bontoxilysin are processed to disulfide-linked subunits of 100 and 50 kDa, the latter being responsible for the endopeptidase activities. Weakly inhibited by captopril, and phosphoramidon. Toxicity is due to action at the neuromuscular junctions that blocks release of acetylcholine, causing flaccid paralysis, in contrast to the spastic paralysis caused by tentoxilysin. In peptidase family M27 (tentoxilysin family). Group: Enzymes. Synonyms: botulinum neurotoxin; BoNT. Enzyme Commission Number: EC 3.4.24.69. CAS No. 107231-12-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4352; bontoxilysin; EC 3.4.24.69; 107231-12-9; botulinum neurotoxin; BoNT. Cat No: EXWM-4352. | |
| bothrolysin | A 22.5 kDa endopeptidase from the venom of the jararaca snake (Bothrops jararaca), insensitive to phosphoramidon at 0.5 mM. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: Bothrops metalloendopeptidase J; J protease. Enzyme Commission Number: EC 3.4.24.50. CAS No. 443890-65-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4332; bothrolysin; EC 3.4.24.50; 443890-65-1; Bothrops metalloendopeptidase J; J protease. Cat No: EXWM-4332. | |
| deuterolysin | Proteolytic activity found in Penicillium roqueforti, P. caseicolum, Aspergillus sojae and A. oryzae. Optimum pH of 5 for digesting various proteins. Strong action on protamine and histones. Insensitive to phosphoramidon. About 20 kDa. A distinct Aspergillus sojae endopeptidase is larger and has a neutral pH optimum. Type example of peptidase family M35. Formerly included in EC 3.4.24.4. Group: Enzymes. Synonyms: Penicillium roqueforti protease II; microbial neutral proteinase II; acid metalloproteinase; neutral proteinase II; Penicillium roqueforti metalloproteinase. Enzyme Commission Number: EC 3.4.24.39. CAS No. 247028-11-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4321; deuterolysin; EC 3.4.24.39; 247028-11-1; Penicillium roqueforti protease II; microbial neutral proteinase II; acid metalloproteinase; neutral proteinase II; Penicillium roqueforti metalloproteinase. Cat No: EXWM-4321. | |
| Ecadotril | Ecadotril is a neutral endopeptidase(NEP) inhibitor and determined by the presence of peptidase family M13 as a neutral endopeptidase inhibited by phosphoramidon. lt is the (S)-enantiomer of racecadotril. It acts as an antihypertensive. Uses: Ecadotril acts as an antihypertensive. Synonyms: Ecadotril; BAY y 7432; BAY-y 7432; BP 1.02; S049; S.049; Sinorphan; N-[(S)-2-[(Acetylthio)methyl]-1-oxo-3-phenylpropyl]glycine benzyl ester;S-Acetorphan;Sinorphan;Benzyl 2-[[(2S)-2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate; Glycine, N-(2-((acetylthio)methyl)-1-oxo-3-phenylpropyl)-, phenylmethyl ester, (S)-. Grades: 95%. CAS No. 112573-73-6. Molecular formula: C21H23NO4S. Mole weight: 385.48. | |
| endothelin-converting enzyme 1 | A phosphoramidon-sensitive metalloendopeptidase in peptidase family M13 (neprilysin family). An integral membrane protein predominantly of endothelial cells, which generates the potent vasoconstrictor endothelin 1 from its inactive precursor. Group: Enzymes. Synonyms: endothelin-converting enzyme; ECE-1. Enzyme Commission Number: EC 3.4.24.71. CAS No. 138238-81-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4355; endothelin-converting enzyme 1; EC 3.4.24.71; 138238-81-0; endothelin-converting enzyme; ECE-1. Cat No: EXWM-4355. | |
| gametolysin | A glycoprotein found in the periplasmic space of Chlamydomonas reinhardtii gametes in a 62 kDa inactive form; decreased to 60 kDa upon activation. A zinc enzyme, inhibited by phosphoramidon, but also thiol activated. Type example of peptidase family M11. Group: Enzymes. Synonyms: autolysin, Chlamydomonas cell wall degrading protease; lysin; Chlamydomonas reinhardtii metalloproteinase; gamete lytic enzyme; gamete autolysin. Enzyme Commission Number: EC 3.4.24.38. CAS No. 97089-74-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4320; gametolysin; EC 3.4.24.38; 97089-74-2; autolysin, Chlamydomonas cell wall degrading protease; lysin; Chlamydomonas reinhardtii metalloproteinase; gamete lytic enzyme; gamete autolysin. Cat No: EXWM-4320. | |
| insulysin | A 110 kDa cytosolic enzyme, known from mammals and the fruit fly, Drosophila melanogaster. Inhibited by bacitracin, chelating agents EDTA and 1,10-phenanthroline, and by thiol-blocking reagents such as N-ethylmaleimide, but not by phosphoramidon. In peptidase family M16 (pitrilysin family). Group: Enzymes. Synonyms: insulinase; insulin-degrading enzyme; insulin protease; insulin proteinase; insulin-degrading neutral proteinase; insulin-specific protease; insulin-glucagon protease; metalloinsulinase; IDE. Enzyme Commission Number: EC 3.4.24.56. CAS No. 9013-83-6. IDE. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4338; insulysin; EC 3.4.24.56; 9013-83-6; insulinase; insulin-degrading enzyme; insulin protease; insulin proteinase; insulin-degrading neutral proteinase; insulin-specific protease; insulin-glucagon protease; metalloinsulinase; IDE. Cat No: EXWM-4338. | |
| L-Tryptophan,N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl- | L-Tryptophan,N-[[(6-deoxy-a-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl-. Uses: Designed for use in research and industrial production. Additional or Alternative Names: eucyl)-;l-tryptophan,n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-l;n-(n-(((6-deoxy-alpha-l-mannopyranosyl)oxy)hydroxyphosphinyl)-l-leucyl)-l-tr;yptophan;PHOSPHORAMIDON;PHOSPHORAMIDON DISODIUM SALT DIHYDRATE;PHOSPHORAMIDON SODIUM SALT. Product Category: Heterocyclic Organic Compound. CAS No. 36357-77-4. Molecular formula: C23H34N3O10P. Mole weight: 543.5. Purity: Purity >98% (HPLC). Density: 1.48 g/cm³. Product ID: ACM36357774. Alfa Chemistry ISO 9001:2015 Certified. |  |
| meprin B | A brush border membrane-bound metalloendopeptidase known from the intestine of all mouse strains that have been tested, and the kidney of certain inbred strains. A tetramer of meprin β subunits (in contrast to meprin A, which contains both α and β subunits). Occurs in the kidney as a proenzyme that can be activated by trypsin. Meprin B is inhibited by both EDTA and 1,10-phenanthroline, but not by phosphoramidon, captopril or thiorphan. In peptidase family M12 (astacin family). Group: Enzymes. Synonyms: meprin-b. Enzyme Commission Number: EC 3.4.24.63. CAS No. 150679-52-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4346; meprin B; EC 3.4.24.63; 150679-52-0; meprin-b. Cat No: EXWM-4346. | |
| neprilysin | A membrane-bound glycoprotein widely distributed in animal tissues. Inhibited by phosphoramidon and thiorphan. Common acute lymphoblastic leukemia antigen (CALLA). Type example of peptidase family M13. Group: Enzymes. Synonyms: neutral endopeptidase; endopeptidase 24.11; kidney-brush-border neutral peptidase; enkephalinase (misleading); endopeptidase-2; CALLA (common acute lymphoblastic leukemia-associated) antigens; CALLA antigen; endopeptidase; membrane metallo. Enzyme Commission Number: EC 3.4.24.11. CAS No. 82707-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4292; neprilysin; EC 3.4.24.11; 82707-54-8; neutral endopeptidase; endopeptidase 24.11; kidney-brush-border neutral peptidase; enkephalinase (misleading); endopeptidase-2; CALLA (common acute lymphoblastic leukemia-associated) antigens; CALLA antigen; endopeptidase; membrane metalloendopeptidase; kidney-brush-border neutral endopeptidase; kidney-brush-border neutral proteinase; endopeptidase-2; CALLA glycoprotein; CALLA; common acute lymphoblastic leukemia antigen; CALLA glycoproteins; common acute lymphoblastic leukemia-associated antigens; neutral metallendopeptidase; membrane metalloendopeptidase; NEP; neutral endopeptidase 24.11; CD10; neutral endopeptidase; acute lymphoblastic leukemia antigen. Cat No: EXWM-4292. | |
| tentoxilysin | Zinc enzyme produced by Clostridium tetani. Proenzyme of 150 kDa is processed to disulfide-linked subunits of 100 and 50 kDa, the latter being responsible for the endopeptidase activity. Weakly inhibited by captopril, and phosphoramidon. The clostridial neurotoxins disable the neuroexocytosis apparatus, and have been described as the most toxic substances known. Tentoxilysin acts at the spinal inhibitory interneurons, blocking the release of various neurotransmitters to produce spastic paralysis. Type example of peptidase family M27 (tentoxilysin family). Group: Enzymes. Synonyms: tetanus neurotoxin. Enzyme Commission Number: EC 3.4.24.68. CAS No. 107231-12-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4351; tentoxilysin; EC 3.4.24.68; 107231-12-9; tetanus neurotoxin. Cat No: EXWM-4351. | |
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