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| Product | Description | |
|---|---|---|
| phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase | The enzyme, characterized from the bacterium Eggerthella lenta, is involed in degradation of methylphosphonate. Group: Enzymes. Synonyms: cyclic phosphate dihydrolase; phnPP (gene name). Enzyme Commission Number: EC 3.1.4.57. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3740; phosphoribosyl 1,2-cyclic phosphate 1,2-diphosphodiesterase; EC 3.1.4.57; cyclic phosphate dihydrolase; phnPP (gene name). Cat No: EXWM-3740. |  |
| phosphoribosyl 1,2-cyclic phosphate phosphodiesterase | Binds Mn2+ and Zn2+. Isolated from the bacterium Escherichia coli, where it participates in the degradation of methylphosphonate. Group: Enzymes. Synonyms: phnP (gene name). Enzyme Commission Number: EC 3.1.4.55. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3738; phosphoribosyl 1,2-cyclic phosphate phosphodiesterase; EC 3.1.4.55; phnP (gene name). Cat No: EXWM-3738. | |
| phosphoribosylamine-glycine ligase | This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. Group: Enzymes. Synonyms: phosphoribosylglycinamide synthetase; glycinamide ribonucleotide synthetase; phosphoribosylglycineamide synthetase; glycineamide ribonucleotide synthetase; 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase; 5'-phosphoribosylglycinamide synthetase; GAR. Enzyme Commission Number: EC 6.3.4.13. CAS No. 9032-1-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5782; phosphoribosylamine-glycine ligase; EC 6.3.4.13; 9032-01-3; phosphoribosylglycinamide synthetase; glycinamide ribonucleotide synthetase; phosphoribosylglycineamide synthetase; glycineamide ribonucleotide synthetase; 2-amino-N-ribosylacetamide 5'-phosphate kinosynthase; 5'-phosphoribosylglycinamide synthetase; GAR. Cat No: EXWM-5782. | |
| phosphoribosyl aminoimidazolecarboxamide formyltransferase | This enzyme participates in purine metabolism and one carbon pool by folate. Group: Enzymes. Synonyms: 5-amino-4-imidazolecarboxamide ribonucleotide transformylase; AICAR transformylase; 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase; 5-amino-4-imidazolecarboxamide ribotide transformylase; AICAR formyltransferase; aminoimidazolecarboxamide ribonucleotide transformylase. Enzyme Commission Number: EC 2.1.2.3. CAS No. 9032-3-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2005; phosphoribosyl aminoimidazolecarboxamide formyltransferase; EC 2.1.2.3; 9032-03-5; 5-amino-4-imidazolecarboxamide ribonucleotide transformylase; AICAR transformylase; 10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase; 5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase; 5-amino-4-imidazolecarboxamide ribotide transformylase; AICAR formyltransferase; aminoimidazolecarboxamide ribonucleotide transformylase. Cat No: EXWM-2005. | |
| phosphoribosylaminoimidazole carboxylase | While this is the reaction that occurs in vertebrates during purine biosynthesis, two enzymes are required to carry out the same reaction in Escherichia coli, namely EC 6.3.4.18, 5-(carboxyamino)imidazole ribonucleotide synthase and EC 5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase. 5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole is not a substrate. Group: Enzymes. Synonyms: 5-phosphoribosyl-5-aminoimidazole carboxylase; 5-amino-1-ribosylimidazole 5-phosphate carboxylase; AIR carboxylase; 1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase; ADE2; class II PurE; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.21. CAS No. 9032-4-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4766; phosphoribosylaminoimidazole carboxylase; EC 4.1.1.21; 9032-04-6; 5-phosphoribosyl-5-aminoimidazole carboxylase; 5-amino-1-ribosylimidazole 5-phosphate carboxylase; AIR carboxylase; 1-(5-phosphoribosyl)-5-amino-4-imidazolecarboxylate carboxy-lyase; ADE2; class II PurE; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate carboxy-lyase. Cat No: EXWM-4766. | |
| phosphoribosyl aminoimidazolesuccinocarboxamide synthase | Forms part of the purine biosynthesis pathway. Group: Enzymes. Synonyms: phosphoribosylaminoimidazole-succinocarboxamide synthetase; PurC; SAICAR synthetase; 4-(N-succinocarboxamide)-5-aminoimidazole synthetase; 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase; SAICARs; phosphoribosyl aminoimidazolesuccinocarboxamide synthetase; 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase. Enzyme Commission Number: EC 6.3.2.6. CAS No. 9023-67-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5769; phosphoribosyl aminoimidazolesuccinocarboxamide synthase; EC 6.3.2.6; 9023-67-0; phosphoribosylaminoimidazole-succinocarboxamide synthetase; PurC; SAICAR synthetase; 4-(N-succinocarboxamide)-5-aminoimidazole synthetase; 4-[(N-succinylamino)carbonyl]-5-aminoimidazole ribonucleotide synthetase; SAICARs; phosphoribosyl aminoimidazolesuccinocarboxamide synthetase; 5-aminoimidazole-4-N-succinocarboxamide ribonucleotide synthetase. Cat No: EXWM-5769. | |
| phosphoribosyl-AMP cyclohydrolase | The Neurospora crassa enzyme also catalyses the reactions of EC 1.1.1.23 (histidinol dehydrogenase) and EC 3.6.1.31 (phosphoribosyl-ATP diphosphatase). Group: Enzymes. Synonyms: PRAMP-cyclohydrolase; phosphoribosyladenosine monophosphate cyclohydrolase; 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase. Enzyme Commission Number: EC 3.5.4.19. CAS No. 37289-22-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4545; phosphoribosyl-AMP cyclohydrolase; EC 3.5.4.19; 37289-22-8; PRAMP-cyclohydrolase; phosphoribosyladenosine monophosphate cyclohydrolase; 1-(5-phospho-D-ribosyl)-AMP 1,6-hydrolase. Cat No: EXWM-4545. | |
| phosphoribosylanthranilate isomerase | In some organisms, this enzyme is part of a multifunctional protein, together with one or more other components of the system for the biosynthesis of tryptophan [EC 2.4.2.18 (anthranilate phosphoribosyltransferase), EC 4.1.1.48 (indole-3-glycerol-phosphate synthase), EC 4.1.3.27 (anthranilate synthase) and EC 4.2.1.20 (tryptophan synthase)]. Group: Enzymes. Synonyms: PRA isomerase; PRAI; IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex); N-(5-phospho-β-D-ribosyl)anthranilate ketol-isomerase. Enzyme Commission Number: EC 5.3.1.24. CAS No. 37259-82-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5463; phosphoribosylanthranilate isomerase; EC 5.3.1.24; 37259-82-8; PRA isomerase; PRAI; IGPS:PRAI (indole-3-glycerol-phosphate synthetase/N-5'-phosphoribosylanthranilate isomerase complex); N-(5-phospho-β-D-ribosyl)anthranilate ketol-isomerase. Cat No: EXWM-5463. | |
| phosphoribosyl-ATP diphosphatase | The Neurospora crassa enzyme also catalyses the reactions of EC 1.1.1.23 (histidinol dehydrogenase) and EC 3.5.4.19 (phosphoribosyl-AMP cyclohydrolase). Group: Enzymes. Synonyms: phosphoribosyl-ATP pyrophosphatase; phosphoribosyladenosine triphosphate pyrophosphatase; 1-(5-phosphoribosyl)-ATP diphosphohydrolase. Enzyme Commission Number: EC 3.6.1.31. CAS No. 69553-55-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4615; phosphoribosyl-ATP diphosphatase; EC 3.6.1.31; 69553-55-5; phosphoribosyl-ATP pyrophosphatase; phosphoribosyladenosine triphosphate pyrophosphatase; 1-(5-phosphoribosyl)-ATP diphosphohydrolase. Cat No: EXWM-4615. | |
| phosphoribosylformylglycinamidine cyclo-ligase | AIR synthetase is the fifth enzyme in the de novo synthesis of purine nucleotides. It catalyzes the reaction to form 5-aminoimidizole ribonucleotide (AIR) from formylglycinamidine-ribonucleotide FGAM. Group: Enzymes. Synonyms: phosphoribosylaminoimidazole synthetase; AIR synthetase; 5'-aminoimidazole ribonucleotide synthetase; 2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming). Enzyme Commission Number: EC 6.3.3.1. CAS No. 9023-53-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5773; phosphoribosylformylglycinamidine cyclo-ligase; EC 6.3.3.1; 9023-53-4; phosphoribosylaminoimidazole synthetase; AIR synthetase; 5'-aminoimidazole ribonucleotide synthetase; 2-(formamido)-1-N-(5-phosphoribosyl)acetamidine cyclo-ligase (ADP-forming). Cat No: EXWM-5773. | |
| phosphoribosylformylglycinamidine synthase | This enzyme belongs to the family of ligases, specifically those forming carbon-nitrogen bonds carbon-nitrogen ligases with glutamine as amido-N-donor. This enzyme participates in purine metabolism. Group: Enzymes. Synonyms: phosphoribosylformylglycinamidine synthetase; formylglycinamide ribonucloetide amidotransferase; phosphoribosylformylglycineamidine synthetase; FGAM synthetase; FGAR amidotransferase; 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming); 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming). Enzyme Commission Number: EC 6.3.5.3. CAS No. 9032-84-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5806; phosphoribosylformylglycinamidine synthase; EC 6.3.5.3; 9032-84-2; phosphoribosylformylglycinamidine synthetase; formylglycinamide ribonucloetide amidotransferase; phosphoribosylformylglycineamidine synthetase; FGAM synthetase; FGAR amidotransferase; 5'-phosphoribosylformylglycinamide:L-glutamine amido-ligase (ADP-forming); 2-N-formyl-1-N-(5-phospho-D-ribosyl)glycinamide:L-glutamine amido-ligase (ADP-forming). Cat No: EXWM-5806. | |
| phosphoribosylglycinamide formyltransferase | This THF dependent enzyme catalyzes a nucleophilic acyl substitution of the formyl group from 10-formyltetrahydrofolate (fTHF) to N1-(5-phospho-D-ribosyl)glycinamide (GAR) to form N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide (fGAR) as shown above. This reaction plays an important role in the formation of purine through the de novo purine biosynthesis pathway. This pathway creates inosine monophosphate (IMP), a precursor to adenosine monophosphate (AMP) and guanosine monophosphate (GMP). Group: Enzymes. Synonyms: 2-amino-N-ribosylacetamide 5'-phosphate transformylase; GAR formyltransferase; GAR transformylase; glycinamide ribonucleotide transformylase; GAR TFase; 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase. Enzyme Commission Number: EC 2.1.2.2. CAS No. 9032-2-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2004; phosphoribosylglycinamide formyltransferase; EC 2.1.2.2; 9032-02-4; 2-amino-N-ribosylacetamide 5'-phosphate transformylase; GAR formyltransferase; GAR transformylase; glycinamide ribonucleotide transformylase; GAR TFase; 5,10-methenyltetrahydrofolate:2-amino-N-ribosylacetamide ribonucleotide transformylase. Cat No: EXWM-2004. | |
| Phosphoribosyl pyrophosphate | 5-O-phosphono-alpha-D-ribofuranosyl diphosphate is a derivative of alpha-D-ribose having a phosphate group at the 5-position and a diphosphate at the 1-position. It has a role as a human metabolite, a plant metabolite, an Escherichia coli metabolite and a mouse metabolite. It derives from an alpha-D-ribose. It is a conjugate acid of a 5-O-phosphonato-alpha-D-ribofuranosyl diphosphate(5-). Synonyms: a-D-Ribofuranose 5-(dihydrogen phosphate)1-(trihydrogen diphosphate); PRPP; Phosphoribosyl-1-pyrophosphate; 5-phospho-alpha-D-ribose 1-diphosphate; 5-O-phosphono-α-D-ribofuranosyl diphosphate; PRib-PP; [(2R,3R,4S,5R)-3,4-dihydroxy-5-(phosphonooxymethyl)oxolan-2-yl] phosphono hydrogen phosphate. CAS No. 7540-64-9. Molecular formula: C5H13O14P3. Mole weight: 390.07. |  |
| 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase | Involved in histidine biosynthesis. Group: Enzymes. Synonyms: N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosyl formiminoaminophosphoribosyl imidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosyl imidazolecarboxamide isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosyla. Enzyme Commission Number: EC 5.3.1.16. CAS No. 37318-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5457; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide isomerase; EC 5.3.1.16; 37318-43-7; N-(5'-phospho-D-ribosylformimino)-5-amino-1-(5''-phosphoribosyl)-4-imidazolecarboxamide isomerase; phosphoribosyl formiminoaminophosphoribosyl imidazolecarboxamide isomerase; N-(phosphoribosylformimino) aminophosphoribosyl imidazolecarboxamide isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide ketol-isomerase; 1- (5-phosphoribosyl) -5-[ (5-phosphoribosylamino) methylideneamino]imidazole-4-carboxamide aldose-ketose-isomerase. Cat No: EXWM-5457. | |
| 5-amino-6-(5-phosphoribosylamino)uracil reductase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 5-amino-6-(5-phosphoribitylamino)uracil:NADP+ 1'-oxidoreductase. This enzyme is also called aminodioxyphosphoribosyl aminopyrimidine reductase. This enzyme participates in riboflavin metabolism. Group: Enzymes. Synonyms: aminodioxyphosphoribosyl aminopyrimidine reductase. Enzyme Commission Number: EC 1.1.1.193. CAS No. 69020-28-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0096; 5-amino-6-(5-phosphoribosylamino)uracil reductase; EC 1.1.1.193; 69020-28-6; aminodioxyphosphoribosyl aminopyrimidine reductase. Cat No: EXWM-0096. | |
| adenine phosphoribosyltransferase | 5-Amino-4-imidazolecarboxamide can replace adenine. Group: Enzymes. Synonyms: AMP pyrophosphorylase; transphosphoribosidase; APRT; AMP-pyrophosphate phosphoribosyltransferase; adenine phosphoribosylpyrophosphate transferase; adenosine phosphoribosyltransferase; adenylate pyrophosphorylase; adenylic pyrophosphorylase. Enzyme Commission Number: EC 2.4.2.7. CAS No. 9027-80-9. APRT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2690; adenine phosphoribosyltransferase; EC 2.4.2.7; 9027-80-9; AMP pyrophosphorylase; transphosphoribosidase; APRT; AMP-pyrophosphate phosphoribosyltransferase; adenine phosphoribosylpyrophosphate transferase; adenosine phosphoribosyltransferase; adenylate pyrophosphorylase; adenylic pyrophosphorylase. Cat No: EXWM-2690. | |
| amidophosphoribosyltransferase | Amidophosphoribosyltransferase (ATase), also known as glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an enzyme responsible for catalyzing the conversion of 5-phosphoribosyl-1-pyrophosphate (PRPP) into 5-phosphoribosyl-1-amine (PRA), using the ammonia group from a glutamine side-chain. This is the committing step in de novo purine synthesis. In humans it is encoded by the PPAT (phosphoribosyl pyrophosphate amidotransferase) gene. ATase is a member of the purine/pyrimidine phosphoribosyltransferase family. Group: Enzymes. Synonyms: phosphoribosyldiphosphate 5-amidotransfer. Enzyme Commission Number: EC 2.4.2.14. CAS No. 9031-82-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2641; amidophosphoribosyltransferase; EC 2.4.2.14; 9031-82-7; phosphoribosyldiphosphate 5-amidotransferase; glutamine phosphoribosyldiphosphate amidotransferase; α-5-phosphoribosyl-1-pyrophosphate amidotransferase; 5'-phosphoribosylpyrophosphate amidotransferase; 5-phosphoribosyl-1-pyrophosphate amidotransferase; 5-phosphororibosyl-1-pyrophosphate amidotransferase; glutamine 5-phosphoribosylpyrophosphate amidotransferase; glutamine ribosylpyrophosphate 5-phosphate amidotransferase; phosphoribose pyrophosphate amidotransferase; phosphoribosyl pyrophosphate amidotransfe | |
| anthranilate phosphoribosyltransferase | In some organisms, this enzyme is part of a multifunctional protein together with one or more other components of the system for biosynthesis of tryptophan [EC 4.1.1.48 (indole-3-glycerol-phosphate synthase), EC 4.1.3.27 (anthranilate synthase), EC 4.2.1.20 (tryptophan synthase) and EC 5.3.1.24 (phosphoribosylanthranilate isomerase)]. Group: Enzymes. Synonyms: phosphoribosyl-anthranilate pyrophosphorylase; PRT; anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase; anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase; phosphoribosylanthranilate pyrophosphorylase; phosphoribosylanthranilate transferase; anthranilate-PP-ribose-P phosphoribosyltransferase. Enzyme Commission Number: EC 2.4.2.18. CAS No. 9059-35-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2645; anthranilate phosphoribosyltransferase; EC 2.4.2.18; 9059-35-2; phosphoribosyl-anthranilate pyrophosphorylase; PRT; anthranilate 5-phosphoribosylpyrophosphate phosphoribosyltransferase; anthranilate phosphoribosylpyrophosphate phosphoribosyltransferase; phosphoribosylanthranilate pyrophosphorylase; phosphoribosylanthranilate transferase; anthranilate-PP-ribose-P phosphoribosyltransferase. Cat No: EXWM-2645. | |
| ATP phosphoribosyltransferase | Involved in histidine biosynthesis. Group: Enzymes. Synonyms: phosphoribosyl-ATP pyrophosphorylase; adenosine triphosphate phosphoribosyltransferase; phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase; phosphoribosyl ATP synthetase; phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase; phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase; phosphoribosyladenosine triphosphate pyrophosphorylase; phosphoribosyladenosine triphosphate synthetase; 1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-α-D-ribosyl-transferase. Enzyme Commission Number: EC 2.4.2.17. CAS No. 9031-46-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2644; ATP phosphoribosyltransferase; EC 2.4.2.17; 9031-46-3; phosphoribosyl-ATP pyrophosphorylase; adenosine triphosphate phosphoribosyltransferase; phosphoribosyladenosine triphosphate:pyrophosphate phosphoribosyltransferase; phosphoribosyl ATP synthetase; phosphoribosyl ATP:pyrophosphate phosphoribosyltransferase; phosphoribosyl-ATP:pyrophosphate-phosphoribosyl phosphotransferase; phosphoribosyladenosine triphosphate pyrophosphorylase; phosphoribosyladenosine triphosphate synthetase; 1-(5-phospho-D-ribosyl)-ATP:diphosphate phospho-α-D-ribosyl-transferase. Cat No: EXWM-2644. | |
| decaprenyl-phosphate phosphoribosyltransferase | Requires Mg2+. Isolated from Mycobacterium tuberculosis. Has some activity with other polyprenyl phosphates. Group: Enzymes. Synonyms: 5-phospho-α-D-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase; 5-phospho-α-D-ribose 1-pyrophosphate:decaprenyl phosphate 5-phosphoribosyltransferase; DPPR synthase; Rv3806. Enzyme Commission Number: EC 2.4.2.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2674; decaprenyl-phosphate phosphoribosyltransferase; EC 2.4.2.45; 5-phospho-α-D-ribose-1-diphosphate:decaprenyl-phosphate 5-phosphoribosyltransferase; 5-phospho-α-D-ribose 1-pyrophosphate:decaprenyl phosphate 5-phosphoribosyltransferase; DPPR synthase; Rv3806. Cat No: EXWM-2674. | |
| dioxotetrahydropyrimidine phosphoribosyltransferase | Acts (in the reverse direction) on uracil and other pyrimidines and pteridines containing a 2,4-diketo structure. Group: Enzymes. Synonyms: dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase; dioxotetrahydropyrimidine phosphoribosyl transferase; dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase; 2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Enzyme Commission Number: EC 2.4.2.20. CAS No. 37277-75-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2648; dioxotetrahydropyrimidine phosphoribosyltransferase; EC 2.4.2.20; 37277-75-1; dioxotetrahydropyrimidine-ribonucleotide pyrophosphorylase; dioxotetrahydropyrimidine phosphoribosyl transferase; dioxotetrahydropyrimidine ribonucleotide pyrophosphorylase; 2,4-dioxotetrahydropyrimidine-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Cat No: EXWM-2648. | |
| formate-phosphoribosyl aminoimidazolecarboxamide ligase | This archaeal enzyme, characterized from the methanogen Methanocaldococcus jannaschii, catalyses a step in the synthesis of purine nucleotides. It differs from the orthologous bacterial/eukaryotic enzymes, which utilize 10-formyltetrahydrofolate rather than formate and ATP. cf. EC 2.1.2.3, phosphoribosyl aminoimidazolecarboxamide formyltransferase. Group: Enzymes. Synonyms: 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase; 5-formaminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate synthetase; purP (gene name). Enzyme Commission Number: EC 6.3.4.23. CAS No. 9032-3-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5793; formate-phosphoribosyl aminoimidazolecarboxamide ligase; EC 6.3.4.23; 9032-03-5; 5-formaminoimidazole-4-carboxamide ribonucleotide synthetase; 5-formaminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate synthetase; purP (gene name). Cat No: EXWM-5793. | |
| Hypoxanthine-guanine phosphoribosyltransferase from Human, Recombinant | HGPRT is a highly active enzyme that catalyzes the reversible transfer of the 5-phosphoribosyl group between α-D-5-phosphoribosyl-1-pyrophosphate (PRPP) and a purine base (hypoxanthine or guanine) to form a purine nucleotide IMP or GMP. The enzyme has been characterized for its affinity for natural substrates and velocity in forward and reverse directions. Group: Enzymes. Synonyms: Hypoxanthine phosphoribosyltransferase; HGPRTase; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; EC 2.4.2.8. Enzyme Commission Number: EC 2.4.2.8. CAS No. 9016-12-0. HGPRT. Mole weight: 25kDa. Activity: > 1 Unit/mg protein. Storage: HPRT enzyme is provided in lyophilized form and should be stored at -20°C. Source: E. coli. Species: Human. Hypoxanthine phosphoribosyltransferase; HGPRTase; HPRT; Hypoxanthine-guanine phosphoribosyltransferase; HGPRT; EC 2.4.2.8. Cat No: NATE-1166. | |
| hypoxanthine phosphoribosyltransferase | Guanine and 6-mercaptopurine can replace hypoxanthine. Group: Enzymes. Synonyms: IMP pyrophosphorylase; transphosphoribosidase; hypoxanthine-guanine phosphoribosyltransferase; guanine phosphoribosyltransferase; GPRT; HPRT; guanosine 5'-phosphate pyrophosphorylase; IMP-GMP pyrophosphorylase; HGPRTase; 6-hydroxypurine phosphoribosyltransferase; 6-mercaptopurine phosphoribosyltransferas. Enzyme Commission Number: EC 2.4.2.8. CAS No. 9016-12-0. HGPRT. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2691; hypoxanthine phosphoribosyltransferase; EC 2.4.2.8; 9016-12-0; IMP pyrophosphorylase; transphosphoribosidase; hypoxanthine-guanine phosphoribosyltransferase; guanine phosphoribosyltransferase; GPRT; HPRT; guanosine 5'-phosphate pyrophosphorylase; IMP-GMP pyrophosphorylase; HGPRTase; 6-hydroxypurine phosphoribosyltransferase; 6-mercaptopurine phosphoribosyltransferase; GMP pyrophosphorylase; guanine-hypoxanthine phosphoribosyltransferase; guanosine phosphoribosyltransferase; guanylate pyrophosphorylase; guanylic pyrophosphorylase; inosinate pyrophosphorylase; inosine 5'-phosphate pyrophosphorylase; inosinic acid pyrophosphorylase; inosinic pyrophosphorylase; 6-mercaptopurine phosphoribosyltransferase; purine-6-thiol phosphoribosyltransferase. Cat No: EXWM-2691. | |
| imidazoleacetate-phosphoribosyldiphosphate ligase | This enzyme belongs to the family of ligases, specifically those forming generic carbon-nitrogen bonds. This enzyme participates in histidine metabolism. Group: Enzymes. Synonyms: 5-phosphoribosylimidazoleacetate synthetase. Enzyme Commission Number: EC 6.3.4.8. CAS No. 37318-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5800; imidazoleacetate-phosphoribosyldiphosphate ligase; EC 6.3.4.8; 37318-65-3; 5-phosphoribosylimidazoleacetate synthetase. Cat No: EXWM-5800. | |
| neamine phosphoribosyltransferase | Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including ribostamycin, neomycin and butirosin. The enzyme requires a divalent metal ion, optimally Mg2+, Ni2+ or Co2+. Group: Enzymes. Synonyms: btrL (gene name); neoM (gene name). Enzyme Commission Number: EC 2.4.2.49. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2678; neamine phosphoribosyltransferase; EC 2.4.2.49; btrL (gene name); neoM (gene name). Cat No: EXWM-2678. | |
| nicotinamide phosphoribosyltransferase | Nicotinamide phosphoribosyltransferase (NAmPRTase or Nampt) also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin is an enzyme that in humans is encoded by the PBEF1 gene. This protein has also been reported to be a cytokine (PBEF) that promotes B cell maturation and inhibits neutrophil apoptosis. Group: Enzymes. Synonyms: NMN pyrophosphorylase; nicotinamide mononucleotide pyrophosphorylase; nicotinamide mononucleotide synthetase; NMN synthetase; nicotinamide-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Enzyme Commission Number: EC 2.4.2.12. CAS No. 9030-27-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2640; nicotinamide phosphoribosyltransferase; EC 2.4.2.12; 9030-27-7; NMN pyrophosphorylase; nicotinamide mononucleotide pyrophosphorylase; nicotinamide mononucleotide synthetase; NMN synthetase; nicotinamide-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Cat No: EXWM-2640. | |
| nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase | Also acts on benzimidazole, and the clostridial enzyme acts on adenine to form 7-α-D-ribosyladenine 5'-phosphate. The product of the reaction, α-ribazole 5'-phosphate, forms part of the corrin-biosynthesis pathway and is a substrate for EC 2.7.8.26, adenosylcobinamide-GDP ribazoletransferase. It can also be dephosphorylated to form α-ribazole by the action of EC 3.1.3.73, α-ribazole phosphatase. Group: Enzymes. Synonyms: nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase; nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase; CobT; nicotinate mononu. Enzyme Commission Number: EC 2.4.2.21. CAS No. 37277-76-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2649; nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; EC 2.4.2.21; 37277-76-2; nicotinate mononucleotide-dimethylbenzimidazole phosphoribosyltransferase; nicotinate ribonucleotide:benzimidazole (adenine) phosphoribosyltransferase; nicotinate-nucleotide:dimethylbenzimidazole phospho-D-ribosyltransferase; CobT; nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole phosphoribosyltransferase. Cat No: EXWM-2649. | |
| nicotinate phosphoribosyltransferase | The enzyme, which is involved in pyridine nucleotide recycling, can form β-nicotinate D-ribonucleotide and diphosphate from nicotinate and 5-phospho-α-D-ribose 1-diphosphate (PRPP) in the absence of ATP. However, when ATP is available the enzyme is phosphorylated resulting in a much lower Km for nicotinate. The phospho-enzyme is hydrolysed during the transferase reaction, regenerating the low affinity form. The presence of ATP shifts the products/substrates equilibrium from 0.67 to 1100. Group: Enzymes. Synonyms: niacin ribonucleotidase; nicotinic acid mononucleotide glycohydrolase; nicotinic acid mononucleotide pyrophosphorylase; nicotinic acid phosphoribosyltransferase; nicotinate-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Enzyme Commission Number: EC 6.3.4.21. CAS No. 9030-26-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5791; nicotinate phosphoribosyltransferase; EC 6.3.4.21; 9030-26-6; niacin ribonucleotidase; nicotinic acid mononucleotide glycohydrolase; nicotinic acid mononucleotide pyrophosphorylase; nicotinic acid phosphoribosyltransferase; nicotinate-nucleotide:diphosphate phospho-α-D-ribosyltransferase. Cat No: EXWM-5791. | |
| orotate phosphoribosyltransferase | The enzyme from higher eukaryotes also catalyses the reaction listed as EC 4.1.1.23, orotidine-5'-phosphate decarboxylase. Group: Enzymes. Synonyms: orotidylic acid phosphorylase; orotidine-5'-phosphate pyrophosphorylase; OPRTase; orotate phosphoribosyl pyrophosphate transferase; orotic acid phosphoribosyltransferase; orotidine 5'-monophosphate pyrophosphorylase; orotidine monophosphate pyrophosphorylase; orotidine phosphoribosyltransferase; orotidylate phosphoribosyltransferase; orotidylate pyrophosphorylase; orotidylic acid pyrophosphorylase; orotidylic phosphorylase; orotidylic pyrophosphorylase. Enzyme Commission Number: EC 2.4.2.10. CAS No. 9030-25-5. OPRTase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2639; orotate phosphoribosyltransferase; EC 2.4.2.10; 9030-25-5; orotidylic acid phosphorylase; orotidine-5'-phosphate pyrophosphorylase; OPRTase; orotate phosphoribosyl pyrophosphate transferase; orotic acid phosphoribosyltransferase; orotidine 5'-monophosphate pyrophosphorylase; orotidine monophosphate pyrophosphorylase; orotidine phosphoribosyltransferase; orotidylate phosphoribosyltransferase; orotidylate pyrophosphorylase; orotidylic acid pyrophosphorylase; orotidylic phosphorylase; orotidylic pyrophosphorylase. Cat No: EXWM-2639. | |
| Recombinant Adenine phosphoribosyltransferase from E. coli | Adenine phosphoribosyltransferase is widely spread in nature, it is produced in bacteria and eukaryotes, participates in the alternative de novo synthesis of purine nucleotides. Group: Enzymes. Synonyms: EC 2.4.2.7; APRT. Enzyme Commission Number: EC 2.4.2.7. CAS No. 9027-80-9. Purity: > 80 %. APRT. Mole weight: 20 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: E. coli. EC 2.4.2.7; APRT; Adenine phosphoribosyltransferase. Cat No: NATE-1004. | |
| Recombinant Adenine phosphoribosyltransferase from Thermus thermophilus | Adenine phosphoribosyltransferase is widely spread in nature, it is produced in bacteria and eukaryotes, participates in the alternative de novo synthesis of purine nucleotides. Group: Enzymes. Synonyms: EC 2.4.2.7; APRT. Enzyme Commission Number: EC 2.4.2.7. CAS No. 9027-80-9. Purity: > 80 %. APRT. Mole weight: 19 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Thermus thermophilus. EC 2.4.2.7; APRT; Adenine phosphoribosyltransferase. Cat No: NATE-1005. | |
| Recombinant Phosphoribosylpyrophosphate synthetase from E. coli | Phosphoribosylpyrophosphate (PRPP) synthetase participates in the biosynthesis in bacteria of purine nucleotides, pyrimidine nucleotides, tryptophan, histidine, and the pyridine nucleotide coenzymes. Group: Enzymes. Synonyms: PRPP synthetase. CAS No. 9031-46-3. Purity: > 80 %. PRPP synthetase. Mole weight: 34 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: E. coli. PRPP synthetase; Phosphoribosyl pyrophosphate synthetase. Cat No: NATE-1007. | |
| Recombinant Phosphoribosylpyrophosphate synthetase from Thermus thermophilus | Phosphoribosylpyrophosphate (PRPP) synthetase participates in the biosynthesis in bacteria of purine nucleotides, pyrimidine nucleotides, tryptophan, histidine, and the pyridine nucleotide coenzymes. Group: Enzymes. Synonyms: PRPP synthetase. CAS No. 9031-46-3. Purity: > 80 %. PRPP synthetase. Mole weight: 32 kDa. Appearance: Colourless clear liquid. Storage: Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Source: E. coli. Species: Thermus thermophilus. PRPP synthetase; Phosphoribosyl pyrophosphate synthetase. Cat No: NATE-1008. | |
| uracil phosphoribosyltransferase | Uracil phosphoribosyltransferase is an enzyme which creates UMP from uracil and phosphoribosylpyrophosphate. This protein may use the morpheein model of allosteric regulation. Group: Enzymes. Synonyms: UMP pyrophosphorylase; UPRTase; UMP:pyrophosphate phosphoribosyltransferase; uridine 5'-phosphate pyrophosphorylase; uridine monophosphate pyrophosphorylase; uridylate pyrophosphorylase; uridylic pyrophosphorylase. Enzyme Commission Number: EC 2.4.2.9. CAS No. 9030-24-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2692; uracil phosphoribosyltransferase; EC 2.4.2.9; 9030-24-4; UMP pyrophosphorylase; UPRTase; UMP:pyrophosphate phosphoribosyltransferase; uridine 5'-phosphate pyrophosphorylase; uridine monophosphate pyrophosphorylase; uridylate pyrophosphorylase; uridylic pyrophosphorylase. Cat No: EXWM-2692. | |
| xanthine phosphoribosyltransferase | This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases.This enzyme participates in purine metabolism. Group: Enzymes. Synonyms: Xan phosphoribosyltransferase; xanthosine 5'-phosphate pyrophosphorylase; xanthylate pyrophosphorylase; xanthylic pyrophosphorylase; XMP pyrophosphorylase; 5-phospho-α-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase; 9-(5-phospho-β-D-ribosyl)xanthine:diphosphate 5-phospho-α-D-ribosyltransferase. Enzyme Commission Number: EC 2.4.2.22. CAS No. 9023-10-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2650; xanthine phosphoribosyltransferase; EC 2.4.2.22; 9023-10-3; Xan phosphoribosyltransferase; xanthosine 5'-phosphate pyrophosphorylase; xanthylate pyrophosphorylase; xanthylic pyrophosphorylase; XMP pyrophosphorylase; 5-phospho-α-D-ribose-1-diphosphate:xanthine phospho-D-ribosyltransferase; 9-(5-phospho-β-D-ribosyl)xanthine:diphosphate 5-phospho-α-D-ribosyltransferase. Cat No: EXWM-2650. | |
| 1,2,3,4-Tetrahydro-2,7-naphthyridine Hydrochloride | 1,2,3,4-Tetrahydro-2,7-naphthyridine is used in the synthetic preparation of potent nicotinamide phosphoribosyl transferase inhibitors with antiproliferative activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 1354940-72-9. Pack Sizes: 25mg, 50mg. Molecular Formula: C8H10N2; HCl, Molecular Weight: 134.183646. US Biological Life Sciences. |  Worldwide |
| 1-Methylbenzimidazole-6-carboxylic Acid | 1-Methylbenzimidazole-6-carboxylic Acid is used as a reagent in the synthesis of aminopyridine-derived amides as nicotinamide phosphoribosyl transferase inhibitors. Also used as a reagent in the synthesis of nitazoxanide-N-methylbenzimidazole hybrids which exhibit antiprotozoal activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 53484-18-7. Pack Sizes: 250mg, 1g. Molecular Formula: C9H8N2O2, Molecular Weight: 176.17. US Biological Life Sciences. | Worldwide |
| 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase | The reaction proceeds in the opposite direction. A step in riboflavin biosynthesis, NADPH and NADH function equally well as reductant. Differs from EC 1.1.1.193 [5-amino-6-(5-phosphoribosylamino)uracil reductase] since it does not catalyse the reduction of 5-amino-6-ribosylaminopyrimidine-2,4(1H,3H)-dione 5'-phosphate. Group: Enzymes. Synonyms: 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; MjaRED; MJ0671 (gene name). Enzyme Commission Number: EC 1.1.1.302. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0213; 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase; EC 1.1.1.302; 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase; MjaRED; MJ0671 (gene name). Cat No: EXWM-0213. | |
| 2,8-Dihydroxyadenine | 2,8-Dihydroxyadenine, an endogenous metabolite, can cause the formation of urinary crystals and kidney stones. 2,8-Dihydroxyadenine can be used to diagnose adenine phosphoribosyltransferase (APRT) deficiency [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 30377-37-8. Pack Sizes: 2.5 mg. Product ID: HY-N9941. |  |
| 3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl- β-D-ribofuranosyl)-pyridinium Triflate | 3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl- β-D-ribofuranosyl)-pyridinium Triflate is an intermediate in synthesizing β-Nicotinamide Mononucleotide (N407765), a product of the extracellular Nicotinamide phosphoribosyl transferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. Group: Biochemicals. Grades: Highly Purified. CAS No. 774599-53-0. Pack Sizes: 50mg, 100mg. Molecular Formula: C17H21N2O8+; CF3O3S-, Molecular Weight: 381.361490699999. US Biological Life Sciences. | Worldwide |
| 3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium Triflate | 3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium Triflate is an intermediate in synthesizing β-Nicotinamide Mononucleotide, a product of the extracellular Nicotinamide phosphoribosyltransferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. Synonyms: 3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium 1,1,1-Trifluoromethanesulfonate; 3-(Aminocarbonyl)-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-pyridinium Salt with Trifluoromethanesulfonic Acid. CAS No. 774599-53-0. Molecular formula: C17H21N2O8? CF3O3S?. Mole weight: 381.36. | |
| 3-(Aminomethyl)pyrazole | 3-(Aminomethyl)pyrazole was used in preparation of pyridinyl- and sulfonylphenyl-substituted ureas as inhibitors of nicotinamide phosphoribosyl transferase. Group: Biochemicals. Grades: Highly Purified. CAS No. 37599-58-9. Pack Sizes: 100mg, 250mg. Molecular Formula: C4H7N3, Molecular Weight: 97.12. US Biological Life Sciences. | Worldwide |
| 3-(Formylamino)-1H-pyrazole-4-carboxamide | An impurity of Allopurinol with inhibitory effects on human hypoxanthine phosphoribosyl transferase. Group: Biochemicals. Alternative Names: 3-Formamidopyrazole-4-carboxamide; Allopurinol Impurity B. Grades: Highly Purified. CAS No. 22407-20-1. Pack Sizes: 250mg. US Biological Life Sciences. | Worldwide |
| 4-Nitrophenyl b-D-ribofuranoside | 4-Nitrophenyl b-D-ribofuranoside, a complex biochemical reagent utilized in laboratory settings as a substrate in the detection of numerous enzymes with which it imperatively interacts. The composition is particularly central to assays of phosphoribosylpyrophosphate synthetase, nucleoside phosphorylase, and ribosyltransferases, and is also highly effective in synthesizing nucleotides and nucleosides for further biochemical analysis. Synonyms: PNP-b-D-riboside. CAS No. 59495-69-1. Molecular formula: C11H13NO7. Mole weight: 271.22. | |
| 5-(carboxyamino)imidazole ribonucleotide mutase | In eubacteria, fungi and plants, this enzyme, along with EC 6.3.4.18, 5-(carboxyamino)imidazole ribonucleotide synthase, is required to carry out the single reaction catalysed by EC 4.1.1.21, phosphoribosylaminoimidazole carboxylase, in vertebrates. In the absence of EC 6.3.2.6, phosphoribosyl aminoimidazolesuccinocarboxamide synthase, the reaction is reversible. The substrate is readily converted into 5-amino-1-(5-phospho-D-ribosyl)imidazole by non-enzymic decarboxylation. Group: Enzymes. Synonyms: N5-CAIR mutase; PurE; N5-carboxyaminoimidazole ribonucleotide mutase; class I PurE. Enzyme Commission Number: EC 5.4.99.18. CAS No. 255379-40-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5557; 5-(carboxyamino)imidazole ribonucleotide mutase; EC 5.4.99.18; 255379-40-9; N5-CAIR mutase; PurE; N5-carboxyaminoimidazole ribonucleotide mutase; class I PurE. Cat No: EXWM-5557. | |
| 5-(carboxyamino)imidazole ribonucleotide synthase | In Escherichia coli, this enzyme, along with EC 5.4.99.18, 5-(carboxyamino)imidazole ribonucleotide mutase, is required to carry out the single reaction catalysed by EC 4.1.1.21, phosphoribosylaminoimidazole carboxylase, in vertebrates. Belongs to the ATP grasp protein superfamily. Carboxyphosphate is the putative acyl phosphate intermediate. Involved in the late stages of purine biosynthesis. Group: Enzymes. Synonyms: N5-CAIR synthetase; N5-carboxyaminoimidazole ribonucleotide synthetase; PurK. Enzyme Commission Number: EC 6.3.4.18. CAS No. 255379-40-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5787; 5-(carboxyamino)imidazole ribonucleotide synthase; EC 6.3.4.18; 255379-40-9; N5-CAIR synthetase; N5-carboxyaminoimidazole ribonucleotide synthetase; PurK. Cat No: EXWM-5787. | |
| ACP-SH:acetate ligase | This enzyme, from the anaerobic bacterium Malonomonas rubra, is a component of the multienzyme complex EC 4.1.1.89, biotin-dependent malonate decarboxylase. The enzyme uses the energy from hydrolysis of ATP to convert the thiol group of the acyl-carrier-protein-bound 2'-(5-phosphoribosyl)-3'-dephospho-CoA prosthetic group into its acetyl thioester. Group: Enzymes. Synonyms: HS-acyl-carrier protein:acetate ligase; [acyl-carrier protein]:acetate ligase; MadH. Enzyme Commission Number: EC 6.2.1.35. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5693; ACP-SH:acetate ligase; EC 6.2.1.35; HS-acyl-carrier protein:acetate ligase; [acyl-carrier protein]:acetate ligase; MadH. Cat No: EXWM-5693. | |
| adenylosuccinate lyase | Also acts on 1-(5-phosphoribosyl)-4-(N-succinocarboxamide)-5-aminoimidazole. Group: Enzymes. Synonyms: adenylosuccinase; succino AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming). Enzyme Commission Number: EC 4.3.2.2. CAS No. 9027-81-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5297; adenylosuccinate lyase; EC 4.3.2.2; 9027-81-0; adenylosuccinase; succino AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase; 6-N-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming). Cat No: EXWM-5297. | |
| AICAR-5'-MP / ZMP | AICAR-5'-MP is an analogue of AICA-riboside, an alternative of 5'-AMP. AICAR-5'-MP is a purine precursor with antineoplastic activity and can be used in the study of type 2 diabetes. It can activate AMP-activated protein kinase. Synonyms: 1H-Imidazole-4-carboxamide, 5-amino-1-(5-O-phosphono-β-D-ribofuranosyl)-; 5-Amino-1-(5-O-phosphono-β-D-ribofuranosyl)-1H-imidazole-4-carboxamide; Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-(dihydrogen phosphate); Imidazole-4-carboxamide, 5-amino-1-β-D-ribofuranosyl-, 5'-phosphate; 5-Amino-1-(5'-phosphofuranoribosyl)-4-imidazolecarboxamide; 5-Amino-1β-D-ribofuranosylimidazole-4-carboxamide 5'-phosphate; 5-Amino-4-imidazolecarboxamide ribonucleoside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribonucleotide; 5-Amino-4-imidazolecarboxamide riboside 5'-monophosphate; 5-Amino-4-imidazolecarboxamide ribotide; 5-Aminoimidazole-4-carboxamide ribonucleotide; 5'-Phospho-β-D-ribosyl-5-amino-4-imidazolecarboxamide; 5'-Phosphoribosyl-5-amino-4-imidazolecarboxamide; Acadesine 5'-monophosphate; AICA Ribotide; AICA-Ribonucleotide; AICAR; AICAR monophosphate; AICAR (5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranosyl 5'-monophosphate); Aminoimidazolecarboxamide ribonucleotide; NSC 283955; NSC 292227; ZMP; ZMP (alarmone). Grades: ≥95%. CAS No. 3031-94-5. Molecular formula: C9H15N4O8P. Mole weight: 338.21. | |
| anthranilate synthase | In some organisms, this enzyme is part of a multifunctional protein, together with one or more other components of the system for the biosynthesis of tryptophan [EC 2.4.2.18 (anthranilate phosphoribosyltransferase ), EC 4.1.1.48 (indole-3-glycerol-phosphate synthase), EC 4.2.1.20 (tryptophan synthase) and EC 5.3.1.24 (phosphoribosylanthranilate isomerase)]. The native enzyme in the complex uses either glutamine or, less efficiently, NH3. The enzyme separated from the complex uses NH3 only. Group: Enzymes. Synonyms: anthranilate synthetase; chorismate lyase; chorismate pyruvate-lyase (amino-accepting); TrpE. Enzyme Commission Number: EC 4.1.3.27. CAS No. 9031-59-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4907; anthranilate synthase; EC 4.1.3.27; 9031-59-8; anthranilate synthetase; chorismate lyase; chorismate pyruvate-lyase (amino-accepting); TrpE. Cat No: EXWM-4907. | |
| barbiturase | Contains zinc and is specific for barbiturate as substrate. Forms part of the oxidative pyrimidine-degrading pathway in some microorganisms, along with EC 1.17.99.4 (uracil/thymine dehydrogenase) and EC 3.5.1.95 (N-malonylurea hydrolase). It was previously thought that the end-products of the reaction were malonate and urea but this has since been disproved. May be involved in the regulation of pyrimidine metabolism, along with EC 2.4.2.9, uracil phosphoribosyltransferase. Group: Enzymes. Enzyme Commission Number: EC 3.5.2.1. CAS No. 9025-16-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4492; barbiturase; EC 3.5.2.1; 9025-16-5. Cat No: EXWM-4492. | |
| β-Nicotinamide-d4 Mononucleotide (d4-major) | β-Nicotinamide-d4 Mononucleotide is the labelled analogue of a product of the extracellular Nicotinamide phosphoribosyl transferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C11H11D4N2O8P. US Biological Life Sciences. | Worldwide |
| β-Nicotinamide mononucleotide | β-nicotinamide mononucleotide (β-NM) is a product of the nicotinamide phosphoribosyltransferase (NAMPT) reaction and a key NAD + intermediate. The pharmacological activities of β-nicotinamide mononucleotide include its role in cellular biochemical functions, cardioprotection, diabetes, Alzheimer's disease, and complications associated with obesity [1]. Uses: Scientific research. Group: Natural products. Alternative Names: β-NM; NMN. CAS No. 1094-61-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-F0004. | |
| β-Nicotinamide Mononucleotide | A product of the extracellular Nicotinamide phosphoribosyl transferase (eNAMPT) reaction and a key NAD+ intermediate. It ameliorates glucose intolerance by restoring NAD+ levels in HFD-induced T2D mice. It also enhances hepatic insulin sensitivity and restores gene expression related to oxidative stress, inflammatory response, and circadian rhythm, partly through SIRT1 activation. β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide ( β-NMN)-activated RNA fragments. Group: Biochemicals. Alternative Names: 3-(Aminocarbonyl)-1-(5-O-phosphono- β -D-ribofuranosyl) pyridinium Inner Salt;3-Carbamoyl-1- β -D-ribofuranosyl pyridinium Hydroxide, 5'-Phosphate Inner Salt; NMN; Nicotinamide Mononucleotide; Nicotinamide Ribonucleoside 5'-Phosphate; Nicotinamide Ribonucleotide; Nicotinamide Ribotide; β-D-NMN; β-NMN; β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1- β-D-ribofuranoside 5?-phosphate. Grades: Highly Purified. CAS No. 1094-61-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C11H15N2O8P, Molecular Weight: 334.22. US Biological Life Sciences. | Worldwide |
| β-Nicotinic Acid Mononucleotide | A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyl transferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. Group: Biochemicals. Alternative Names: 3-Carboxy-1-(5-O-phosphono- β -D-ribofuranosyl) pyridinium Inner Salt; 3-Carboxy-1- β -D-ribofuranosyl pyridinium Hydroxide 5'-Phosphate Inner Salt; Nicotinate Mononucleotide; Nicotinate Ribonucleotide; Nicotinic Acid Ribonucleotide; Nicotinic Acid Ribotide; Nicotinic Mononucleotide; β-NaMN. Grades: Highly Purified. CAS No. 321-02-8. Pack Sizes: 1mg, 5mg, 10mg. US Biological Life Sciences. | Worldwide |
| β-Nicotinic Acid Mononucleotide | A nucleotide of nicotinic acid which is produced from quinolinic acid by quinolinate phosphoribosyltransferase via transfer of a phosphoribose group. It is an intermediate of nicotinic acid adenine dinucleotide (NaAD) which is then converted to NAD via amidation and in turn converted to NADPH. Synonyms: 3-Carboxy-1-(5-O-phosphono-β-D-ribofuranosyl)pyridinium Inner Salt; 3-Carboxy-1-β-D-ribofuranosylpyridinium Hydroxide 5'-Phosphate Inner Salt; Nicotinate Mononucleotide; Nicotinate Ribonucleotide; Nicotinic Acid Ribonucleotide; Nicotinic Acid Ribotide; Nicotinic Mononucleotide; β-NaMN. Grades: 95%. CAS No. 321-02-8. Molecular formula: C11H14NO9P. Mole weight: 335.2. | |
| Boc-(4-aminomethyl) benzoic acid | Boc-(4-aminomethyl) benzoic acid (CAS# 33233-67-9) is the Boc protected form of 4-(Aminomethyl)benzoic Acid (A615230) and is used as a reagent in the synthesis of indoleamide derivatives as EP2 antagonists with high selectivity. 4-(Boc-aminomethyl)benzoic Acid is also used as a reagent in the synthesis of aminopyridine-derived amides as nicotinamide phosphoribosyltransferase inhibitors. Synonyms: Boc-4-Amb-OH; 4-(Boc-aminomethyl)benzoic acid; 4-[(tert-Butoxycarbonylamino)methyl]benzoic acid. Grades: ≥ 98 % (HPLC). CAS No. 33233-67-9. Molecular formula: C13H17NO4. Mole weight: 251.27. | |
| citrate lyase holo-[acyl-carrier protein] synthase | The γ-subunit of EC 4.1.3.6, citrate (pro-3S) lyase, serves as an acyl-carrier protein (ACP) and contains the prosthetic group 2'-(5-triphosphoribosyl)-3'-dephospho-CoA. Synthesis and attachment of the prosthetic group requires the concerted action of this enzyme and EC 2.4.2.52, triphosphoribosyl-dephospho-CoA synthase. In the enzyme from Escherichia coli, the prosthetic group is attached to serine-14 of the ACP via a phosphodiester bond. Group: Enzymes. Synonyms: 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; 2'-(5''-triphosphoribosyl)-3'-dephospho-Co. Enzyme Commission Number: EC 2.7.7.61. CAS No. 312492-44-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3273; citrate lyase holo-[acyl-carrier protein] synthase; EC 2.7.7.61; 312492-44-7; 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase; CitX; holo-ACP synthase (ambiguous); 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase adenylyltransferase; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate lyase 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA transferase; 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA:apo-citrate-lyase adenylyltransferase; holo-citrate lyase synthase (incorrect). Cat No: EXWM-3273. | |
| Favipiravir | Favipiravir (T-705) is a potent viral RNA polymerase inhibitor, it is phosphoribosylated by cellular enzymes to its active form, Favipiravir-ribofuranosyl-5-triphosphate (RTP). Favipiravir-RTP inhibits the influenza viral RNA-dependent RNA polymerase ( RdRP ) activity with an IC 50 of 341 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: T-705. CAS No. 259793-96-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14768. | |
| FK866 | FK866 is a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyl transferase (NMPRTase), that induces tumor cell apoptosis, and thus is a potential anticancer drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 658084-64-1. Pack Sizes: 5mg, 10mg. Molecular Formula: C24H29N3O2, Molecular Weight: 391.51. US Biological Life Sciences. | Worldwide |
| FK866 | FK866 is a non-competitive inhibitor of nicotinamide phosphoribosyltransferase (Nampt) with potential antineoplastic and antiangiogenic activities. FK866 binds to Nampt to suppress the biosynthesis of nicotinamide adenine dinucleotide (NAD+), leading to tumor cell apoptosis. Uses: Potential anticancer agent. Synonyms: Daporinad; (E)-N-[4-(1-benzoylpiperidin-4-yl)butyl]-3-pyridin-3-ylprop-2-enamide; APO 866; FK 866; APO866; FK866; APO-866; FK-866. CAS No. 658084-64-1. Molecular formula: C24H29N3O2. Mole weight: 391.515. | |
| FK 866 hydrochloride | FK 866 hydrochloride is a non-competitive and potent inhibitor of NAMPT (nicotinamide phosphoribosyltransferase, visfatin, PBEF1) (Ki = 0.3 nM) and inhibits NAD biosynthesis. It induces delayed cell death by apoptosis in HepG2 human liver carcinoma cells (IC50 ~1 nM)and induces apoptosis in four different neuroblastoma cell lines. FK 866 exhibits antineoplastic and antiangiogenic activities. Synonyms: FK-866 Hydrochloride; FK 866 Hydrochloride; FK866 Hydrochloride; 2-(E)-N-[4-(1-Benzoyl-4-piperidinyl)butyl]-3-(3-pyridinyl)-2-propenamide hydrochloride. Grades: ≥98% by HPLC. CAS No. 2727965-45-7. Molecular formula: C24H29N3O2.HCl. Mole weight: 427.97. | |
| Formylglycinamide Ribotide | Formylglycinamide Ribotide (FGAR), along with glutamine, takes part in the ATP-dependent synthesis of Formylglycinamidine Ribonucleotide (FGAM) in the fourth step of the purine biosynthetic pathway. Synonyms: 2-(Formylamino)-N-(5-O-phosphono-β-D-ribofuranosyl)acetamide; 2-Formamido-N-β-D-ribofuranosylacetamide 5'-(Dihydrogen phosphate); 5'-Phosphoribosyl-N-formylglycinamide; FGAR; Formylglycinamide Ribonucleotide; N-Formylglycinamide Ribonucleotide; Phosphoribosylformylglycinamide; α-N-Formylglycinamide Ribonucleotide. CAS No. 349-34-8. Molecular formula: C8H15N2O9P. Mole weight: 314.19. | |
| Glycinamide ribonucleotide | Glycineamide ribonucleotide (or GAR) is an intermediate in de novo purine biosynthesis. It is formed from phosphoribosylamine by the enzyme phosphoribosylamine-glycine ligase. In the next step of purine biosynthesis the enzyme phosphoribosylglycinamide formyltransferase acts on GAR to form FGAR. GAR formation is stimulated by Luteinizing hormone (LH) and Chorionic gonadotropin (HCG) via activation of Glc-6-P-dehydrogenase. Synonyms: 5'-Phosphoribosylglycinamide; N1-(5-Phospho-D-ribosyl)glycinamide; [(2R,3S,4R,5R)-5-[(2-aminoacetyl)amino]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate; n-glycyl-5-o-phosphono-|A-d-ribofuranosylamine; 5'-phosphoribosylglycinamide; GAR; N1-(5-Phospho-D-ribosyl)glycinamide; N1-(5-phospho-beta-D-ribosyl)glycinamide. CAS No. 10074-18-7. Molecular formula: C7H15N2O8P. Mole weight: 286.18. | |
| GPP 78 | GPP 78 is a potent inhibitor of Nicotinamide phosphoribosyltransferase (Nampt) with an IC50 value of 3 nM. Synonyms: CAY10618; NMPRTase Inhibitor; N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide. Grades: ≥95%. CAS No. 1202580-59-3. Molecular formula: C27H29N5O. Mole weight: 439.6. | |
| GPP 78 hydrochloride | GPP 78 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), which is subsequently converted to NAD+. It was shown to induce autophagy in neuroblastoma cells. Synonyms: GPP 78 hydrochloride; GPP78 hydrochloride; GPP-78 hydrochloride; N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C27H29N5O.HCl. Mole weight: 476.01. | |
| histidinol dehydrogenase | Also oxidizes L-histidinal. The Neurospora enzyme also catalyses the reactions of EC 3.5.4.19 (phosphoribosyl-AMP cyclohydrolase) and EC 3.6.1.31 (phosphoribosyl-ATP diphosphatase). Group: Enzymes. Synonyms: L-histidinol dehydrogenase. Enzyme Commission Number: EC 1.1.1.23. CAS No. 9028-27-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0136; histidinol dehydrogenase; EC 1.1.1.23; 9028-27-7; L-histidinol dehydrogenase. Cat No: EXWM-0136. | |
| indole-3-glycerol-phosphate synthase | In some organisms, this enzyme is part of a multifunctional protein, together with one or more other components of the system for the biosynthesis of tryptophan [EC 2.4.2.18 (anthranilate phosphoribosyltransferase), EC 4.1.3.27 (anthranilate synthase), EC 4.2.1.20 (tryptophan synthase) and EC 5.3.1.24 (phosphoribosylanthranilate isomerase)]. Group: Enzymes. Synonyms: indoleglycerol phosphate synthetase; indoleglycerol phosphate synthase; indole-3-glycerophosphate synthase; 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing). Enzyme Commission Number: EC 4.1.1.48. CAS No. 9031-60-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4793; indole-3-glycerol-phosphate synthase; EC 4.1.1.48; 9031-60-1; indoleglycerol phosphate synthetase; indoleglycerol phosphate synthase; indole-3-glycerophosphate synthase; 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose-5-phosphate carboxy-lyase (cyclizing). Cat No: EXWM-4793. | |
| NAD Biosynth Inhibitor (SIR Down Regulator) | Nicotinamide phosphoribosyl transferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis. Group: Biochemicals. Alternative Names: SIR Down Regulator. Grades: Highly Purified. CAS No. 658084-64-1. Pack Sizes: 5mg, 25mg. US Biological Life Sciences. | Worldwide |
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