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This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derive from O miscellaneous. The systematic name of this enzyme class is phylloquinone,hydrogen-donor:oxygen oxidoreductase (2,3-epoxidizing). Other names in common use include phylloquinone epoxidase, vitamin K 2,3-epoxidase, vitamin K epoxidase, and vitamin K1 epoxidase. Group: Enzymes. Synonyms: phylloquinone epoxidase; vitamin K 2,3-epoxidase; vitamin K epoxidase; vitamin K1 epoxidase. Enzyme Commission Number: EC 1.14.99.20. CAS No. 54596-37-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1038; phylloquinone monooxygenase (2,3-epoxidizing); EC 1.14.99.20; 54596-37-1; phylloquinone epoxidase; vitamin K 2,3-epoxidase; vitamin K epoxidase; vitamin K1 epoxidase. Cat No: EXWM-1038.
phylloquinone ω-hydroxylase
A heme-thiolate protein (cytochrome P-450). Isolated from human tissue. The enzyme will also act on menaquinone-4. Prolonged action of CYP4F2, but not CYP4F11, on the ω hydroxyl group oxidizes it to the corresponding carboxylic acid. CYP4F2 also oxidizes leukotriene B4; see EC 1.14.13.30, leukotriene-B4 20-monooxygenase. Group: Enzymes. Synonyms: vitamin K1 ω-hydroxylase; CYP4F2; CYP4F11. Enzyme Commission Number: EC 1.14.13.194. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0794; phylloquinone ω-hydroxylase; EC 1.14.13.194; vitamin K1 ω-hydroxylase; CYP4F2; CYP4F11. Cat No: EXWM-0794.
demethylphylloquinone reductase
The enzyme, found in plants and cyanobacteria, is involved in the biosynthesis of phylloquinone (vitamin K1), an electron carrier associated with photosystem I. The enzyme is a type II NADPH dehydrogenase and requires a flavine adenine dinucleotide cofactor. Group: Enzymes. Synonyms: ndbB (gene name); NDC1 (gene name); demethylphylloquinone:NADPH oxidoreductase. Enzyme Commission Number: EC 1.6.5.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1590; demethylphylloquinone reductase; EC 1.6.5.12; ndbB (gene name); NDC1 (gene name); demethylphylloquinone:NADPH oxidoreductase. Cat No: EXWM-1590.
Vitamin K1 (Phylloquinone) (D7)
Isotope-labeled Vitamins2H Labeled Compounds. Alternative Names: Vitamin K1-D7. CAS No. 1233937-39-7. Molecular formula: C31H39D7O2. Mole weight: 457.74. Appearance: Dark yellow/green liquid. IUPACName: 5, 6, 7, 8-tetradeuterio-2-[ (E)-3, 7, 11, 15-tetramethylhexadec-2-enyl]-3- (trideuteriomethyl)naphthalene-1, 4-dione. Density: 0.984 g/mL at 25 °C (77 °F). Catalog: ACM1233937397.
1,4-dihydroxy-2-naphthoyl-CoA hydrolase
This enzyme participates in the synthesis of menaquinones, phylloquinone, as well as several plant pigments. The enzyme from the cyanobacterium Synechocystis sp. PCC 6803 does not accept benzoyl-CoA or phenylacetyl-CoA as substrates. Group: Enzymes. Synonyms: menI (gene name); ydiL (gene name). Enzyme Commission Number: EC 3.1.2.28. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3561; 1,4-dihydroxy-2-naphthoyl-CoA hydrolase; EC 3.1.2.28; menI (gene name); ydiL (gene name). Cat No: EXWM-3561.
1,4-dihydroxy-2-naphthoyl-CoA synthase
This enzyme is involved in the synthesis of 1,4-dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria), phylloquinone (vitamin K1 in plants), and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-dihydroxy-2-naphthoyl-CoA hydrolase. Group: Enzymes. Synonyms: naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Enzyme Commission Number: EC 4.1.3.36. CAS No. 61328-42-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4913; 1,4-dihydroxy-2-naphthoyl-CoA synthase; EC 4.1.3.36; 61328-42-5; naphthoate synthase; 1,4-dihydroxy-2-naphthoate synthase; dihydroxynaphthoate synthase; o-succinylbenzoyl-CoA 1,4-dihydroxy-2-naphthoate-lyase (cyclizing); MenB; o-succinylbenzoyl-CoA dehydratase (cyclizing). Cat No: EXWM-4913.
2,3-Epoxide Vitamin K1
One of the impurities of Vitamin K1, which could be found commonly in green plants and photosynthetic bacteria, and has been found to be related to osteoporosis. Synonyms: 1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-naphth[2,3-b]oxirene-2,7-dione; 2,3-Epoxyphylloquinone; Phylloquinone Oxide; Phylloquinone Epoxide; Phylloquinone-2,3-epoxide; Vitamin K 2,3-Epoxide; Vitamin K Epoxide; Vitamin K Oxide; Vitamin K1 Oxide; Vitamin K1 Epoxide. CAS No. 25486-55-9. Molecular formula: C31H46O3. Mole weight: 466.71.
2-carboxy-1,4-naphthoquinone phytyltransferase
This enzyme, found in plants and cyanobacteria, catalyses a step in the synthesis of phylloquinone (vitamin K1), an electron carrier associated with photosystem I. The enzyme catalyses the transfer of the phytyl chain synthesized by EC 1.3.1.83, geranylgeranyl diphosphate reductase, to 2-carboxy-1,4-naphthoquinone. Group: Enzymes. Synonyms: menA (gene name); ABC4 (gene name); 1,4-dioxo-2-naphthoate phytyltransferase; 1,4-diketo-2-naphthoate phytyltransferase. Enzyme Commission Number: EC 2.5.1.130. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2746; 2-carboxy-1,4-naphthoquinone phytyltransferase; EC 2.5.1.130; menA (gene name); ABC4 (gene name); 1,4-dioxo-2-naphthoate phytyltransferase; 1,4-diketo-2-naphthoate phytyltransferase. Cat No: EXWM-2746.
cis-Vitamin K1 (Z-Phytonadione)
One of the isomer of Vitamin K1, which could be found commonly in green plants and photosynthetic bacteria, and has been found to be related to osteoporosis. Synonyms: 2-Methyl-3-[(2Z,7R,11R)-3,7,11,15-tetramethyl-2-hexadecen-1-yl]-1,4-naphthalenedione; [R-[R*,R*-(Z)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4- naphthalenedione; cis-Phylloquinone. CAS No. 16033-41-3. Molecular formula: C31H46O2. Mole weight: 450.71.
DT Diaphorase from human, Recombinant
DT Diaphorase is a flavoenzyme that catalyzes the oxidation of reduced di-and triphosphopyridine nucleotides. It contains one mole of FAD per mole of enzyme. The enzyme found in rat liver catalyzes the oxidation of NADH and NADPH by various dyes and quinones. The molecular weight is found to be approximately 48 kDa Da. The pH optimum of the enzyme purified from rat liver is found to be 5.0. It is a cytosolic enzyme that catalyzes the two-electron reduction of various quinones. It catalyzes the conversion of vitamin K to vitamin K hydroquinone for utilization in the post-translational γ-glutamyl carboxylation reactions. These reactions are necessary for several proteins involved in blood coagulation. Applications: Human dt diaphorase has been used in a study to assess the development of novel quinone phosphorodiamidate prodrugs. human dt diaphorase has also been used to investigate its crystal structure for the development of a model for its interaction with the cytotoxic prodrug 5-(aziridin-1-yl)-2,4-dinitrobenzamide (cb1954). Group: Enzymes. Synonyms: menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; flavoprotein NAD (P)H-q. Enzyme Commission Number: EC 1.6.99.2. Diaphorase. Mole weight: monomer mol wt 31 kDa. Storage: 2-8°C. F
DT Diaphorase from rat, Recombinant
DT Diaphorase is a flavoenzyme that catalyzes the oxidation of reduced di-and triphosphopyridine nucleotides. It contains one mole of FAD per mole of enzyme. The enzyme found in rat liver catalyzes the oxidation of NADH and NADPH by various dyes and quinones. The molecular weight is found to be approximately 48 kDa Da. The pH optimum of the enzyme purified from rat liver is found to be 5.0. It is a cytosolic enzyme that catalyzes the two-electron reduction of various quinones. It catalyzes the conversion of vitamin K to vitamin K hydroquinone for utilization in the post-translational γ-glutamyl carboxylation reactions. These reactions are necessary for several proteins involved in blood coagulation. Applications: Dt diaphorase from rat has been used in a study to investigate the two-electron reduction of quinones by rat liver. dt diaphorase from rat has also been used in a study to investigate colon cancer chemopreventive efficacy of silibinin through perturbation of xenobiotic metabolizing enzymes. Group: Enzymes. Synonyms: menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; flavoprotein NAD (P)H-qui. Enzyme Commission Number: EC 1.6.99.2. Purity: ~90% (SDS-PAGE). Diaphorase. Mole weight: monomer mol wt 31 kDa. Storage: 2-8°C. Form
NAD(P)H dehydrogenase (quinone)
A flavoprotein. The enzyme catalyses a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone. The animal, but not the plant, form of the enzyme is inhibited by dicoumarol. Group: Enzymes. Synonyms: menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; f. Enzyme Commission Number: EC 1.6.5.2. CAS No. 9032-20-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1591; NAD(P)H dehydrogenase (quinone); EC 1.6.5.2; 9032-20-6; menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; flavoprotein NAD(P)H-quinone reductase; menadione oxidoreductase; NAD(P)H dehydrogenase; NAD(P)H menadione reductase; NAD(P)H-quinone dehydrogenase; NAD(P)H-quinone oxidoreductase; NAD(P)H: (quinone-acceptor)oxidoreductase; NAD(P)H: menadione oxidoreductase; NADH-menadione reductase; naphthoquinone reductase; p-benzoquinone reductase; reduced NAD(P)H dehydrogenase; viologen accepting pyridine nucleotide oxidoreductase; vitamin K reductase; diaphorase; reduced nicotinamide-adenine dinucleotide (phosphate) dehy
Native Porcine NAD(P)H Dehydrogenase (quinone)
DT Diaphorase is a flavoenzyme that catalyzes the oxidation of reduced di-and triphosphopyridine nucleotides. It contains one mole of FAD per mole of enzyme. The enzyme found in rat liver catalyzes the oxidation of NADH and NADPH by various dyes and quinones. The molecular weight is found to be approximately 48 kDa Da. The pH optimum of the enzyme purified from rat liver is found to be 5.0. It is a cytosolic enzyme that catalyzes the two-electron reduction of various quinones. It catalyzes the conversion of vitamin K to vitamin K hydroquinone for utilization in the post-translational γ-glutamyl carboxylation reactions. These reactions are necessary for several pr...hydrogenase; NAD (P)H menadione reductase; NAD (P)H-quinone dehydrogenase; NAD (P)H-quinone oxidoreductase; NAD (P)H: (quinone-acceptor)oxidoreductase. CAS No. 9032-20-6. Diaphorase. Activity: >25 U/mg. Stability: At +2 to +8°C within specification range for 12 months. Appearance: Yellow suspension in ammonium sulfate, 3.2 mol/l. Source: Porcine heart. Species: Porcine. menadione reductase; phylloquinone reductase; quinone reductase; dehydrogenase, reduced nicotinamide adenine dinucleotide (phosphate, quinone); DT-diaphorase; flavoprotein NAD (P)H-quinone reductase; menadione oxidoreductase; NAD (P)H dehydrogenase; NAD (P)H menadione reductase; NAD (P)H-quinone dehydro
photosystem I
Contains chlorophyll, phylloquinones, carotenoids and [4Fe-4S] clusters.Cytochrome c6 can act as an alternative electron donor, and flavodoxin as an alternative acceptor in some species. Group: Enzymes. Enzyme Commission Number: EC 1.97.1.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1691; photosystem I; EC 1.97.1.12. Cat No: EXWM-1691.
Vitamin K1
Occurs widely in green plants, algae, photosynthetic bacteria. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl]-1,4-naphthalenedione; Konakion; Mephyton; Phytonadione; Phytylmenadione; Phytylmenaquinone; Synthex P; Veda K1; Veta K1; Vitamin K1(20); trans-Phylloquinone; α-Phylloquinone; 2',3'-trans-Vitamin K1. Grades: Highly Purified. CAS No. 84-80-0. Pack Sizes: 10g, 25g, 50g, 100g. Molecular Formula: C??H??O?, Molecular Weight: 450.7. US Biological Life Sciences.
Worldwide
Vitamin K1
Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism. Uses: Scientific research. Group: Natural products. Alternative Names: Phylloquinone; Phytomenadione. CAS No. 84-80-0. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-N0684.
Vitamin K1
Vitamin K1 is a fat-soluble vitamin that occurs widely in green plants, algae, photosynthetic bacteria. Vitamin K1 serves as a precursor to vitamin K2 and is essential for the synthesis of proteins required for blood-clotting, bone metabolism, and cell growth. It is commonly used in dietary supplement for the treatment of bleeding disorders. Vitamin supplement in health care products. Uses: Ingredient of health care products. Synonyms: Phytonadione; Phytomenadione; Phylloquinone; 3-Phytylmenadione; E-Phytonadione; 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl]-1,4-naphthalenedione; Konakion; Mephyton; Phytylmenadione; Phytylmenaquinone; Synthex P; Veda K1; Veta K1; trans-Phylloquinone; α-Phylloquinone; 2',3'-trans-Vitamin K1; [R-[R*,R*-(E)]]-2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecenyl)-1,4-naphthalenedione; Antihemorrhagic Vitamin; Haemokion; Kativ N; Kaywan; Kenadion; Kephton; Kinadion; Konakion; Mono-Kay; Monodion; NSC 270681; Orakay; Pediatrico; Phylloquinone K1; Reconval. Grades: 97.0-103.0%. CAS No. 84-80-0. Molecular formula: C31H46O2. Mole weight: 450.71.
Vitamin K1
Vitamin K1 occurs widely in green plants, algae, photosynthetic bacteria. Applications: A chemical which occurs in green plants, algae, photosynthetic bacteria. Group: Coenzymes. Synonyms: Phylloquinone; Phytomenadione. CAS No. 84-80-0. Purity: ≥98%. Mole weight: 450.69. Form: Liquid. Phylloquinone; Phytomenadione; Vitamin K1; 84-80-0. Cat No: COEC-098.
Vitamin K1 2,3-epoxide
Vitamin K1 2,3-epoxide. Group: Biochemicals. Alternative Names: 1a,7a-Dihydro-1a-methyl-7a-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-naphth[2,3-b]oxirene-2,7-dione; 2,3-Epoxyphylloquinone; Phylloquinone oxide. Grades: Highly Purified. CAS No. 25486-55-9. Pack Sizes: 2mg, 5mg, 10mg, 25mg. Molecular Formula: C31H46O3. US Biological Life Sciences.
Worldwide
Vitamin K1, 97.0-103.0% (HPLC) USP
Occurs widely in green plants, algae, photosynthetic bacteria. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl]-1,4-naphthalenedione; Konakion; Mephyton; Phytonadione; Phytylmenadione; Phytylmenaquinone; Synthex P; Veda K1; Veta K1; Vitamin K1(20); trans-Phylloquinone; α-Phylloquinone; 2',3'-trans-Vitamin K1. Grades: USP. CAS No. 84-80-0. Pack Sizes: 1g, 5g, 25g. Molecular Formula: C??H??O?, Molecular Weight: 450.71. US Biological Life Sciences.
Worldwide
Vitamin K1-d7
Labeled Vitamin K1. Occurs widely in green plants, algae, photosynthetic bacteria. Group: Biochemicals. Alternative Names: 2-Methyl-3-[(2E,7R,11R)-3,7,11,15-tetramethyl-2-hexadecenyl]-1,4-naphthalenedione-d7; Konakion-d7; Mephyton-d7; Phytonadione-d7; Phytylmenadione-d7; Phytylmenaquinone-d7; Synthex P-d7; Veda K1-d7; Veta K1-d7; Vitamin K1(20)-d7; trans-Phylloquinone-d7; α-Phylloquinone-d7; 2',3'-trans-Vitamin K1-d7. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
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