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Pimozide is a diphenylbutylpiperidine derivative and a dopamine antagonist with antipsychotic property. Pimozide selectively inhibits type 2 dopaminergic receptors in the central nervous system (CNS), and also inhibits STAT3 and STAT5. Uses: Anti-dyskinesia agents. Synonyms: R6238. Grades: 98%. CAS No. 2062-78-4. Molecular formula: C28H29F2N3O. Mole weight: 461.55.
Pimozide
Pimozide is a dopamine receptor antagonist, with K i s of 1.4 nM, 2.5 nM and 588 nM for dopamine D2, D3 and D1 receptors, respectively, and also has affinity at α1-adrenoceptor , with a K i of 39 nM; Pimozide also inhibits STAT3 and STAT5. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R6238. CAS No. 2062-78-4. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg. Product ID: HY-12987.
Pimozide Impurity A
An impurity of Pimozide (Orap) which has special neurologic indications for Tourette syndrome and resistant tics. Grades: > 95%. Molecular formula: C12H15N3O. Mole weight: 217.27.
Pimozide Impurity B
An impurity of Pimozide (Orap) which is used to reduce uncontrolled movements (motor tics) or outbursts of words/sounds (vocal tics) caused by Tourette syndrome. Grades: > 95%. Molecular formula: C28H30FN3O. Mole weight: 443.57.
Pimozide Impurity C
An impurity of Pimozide (Orap) which is an antipsychotic drug of the diphenylbutylpiperidine class. Grades: > 95%. Molecular formula: C28H29F2N3O. Mole weight: 461.56.
Pimozide Impurity D
An impurity of Pimozide (Orap) which has special neurologic indications for Tourette syndrome and resistant tics. Grades: > 95%. Molecular formula: C28H27F2N3O. Mole weight: 459.54.
Pimozide Impurity E
An impurity of Pimozide (Orap) which is an antipsychotic drug of the diphenylbutylpiperidine class. Synonyms: Pimozide N-Oxide; 1083078-88-9; UNII-KC2BVV76IU; KC2BVV76IU; Pimozide specified impurity E [EP]; 1-(1-(4,4-Bis(4-fluorophenyl)butyl)piperidin-4-yl 1-oxide)-1,3-dihydro-2H-benzimidazol-2-one; 2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-1-oxido-4-piperidinyl)-1,3-dihydro-; 3-[1-[4,4-bis(4-fluorophenyl)butyl]-1-oxidopiperidin-1-ium-4-yl]-1H-benzimidazol-2-one; Pimozide impurity E; SCHEMBL1152903; DTXSID00148496; BCP15238; PIMOZIDE IMPURITY E [EP IMPURITY]; FT-0673904; F97131; Q27282170; 210690-27-0; CIS-(1S,4R)-1-[4,4-BIS(4-FLUOROPHENYL)BUTYL]-4-(2-OXO-2,3-DIHYDRO-1H-1,3-BENZODIAZOL-1-YL)PIPERIDIN-1-IUM-1-OLATE. Grades: > 95%. Molecular formula: C28H29F2N3O2. Mole weight: 477.56.
Pimozide N-Oxide
Pimozide N-Oxide is an impurity of Pimozide with hERG inhibitory activity. Pimozide impurity E. Group: Biochemicals. Alternative Names: 1-[1-[4,4-Bis(4-fluorophenyl)butyl]-1-oxido-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one. Grades: Highly Purified. CAS No. 1083078-88-9. Pack Sizes: 10mg. US Biological Life Sciences.
1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one is an intermediate in the synthesis of Pimozide (D453300), a D2 dopamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 16148-06-4. Pack Sizes: 1g, 5g. Molecular Formula: C19H21N3O. US Biological Life Sciences.
1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one-d5 is an isotope labelled intermediate in the synthesis of Pimozide (D453302), a D2 dopamine receptor antagonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C19H16D5N3O. US Biological Life Sciences.
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1-(4-Bromo-1-phenylbut-1-en-1-yl)-4-fluorobenzene
1-(4-Bromo-1-phenylbut-1-en-1-yl)-4-fluorobenzene is an intermediate formed in the synthesis of Desfluoro Pimozide (D289865), an impurity of Pimozide (P447800). Group: Biochemicals. Grades: Highly Purified. CAS No. 85375-29-7. Pack Sizes: 50mg, 250mg. Molecular Formula: C16H14BrF. US Biological Life Sciences.
Worldwide
1-(4-Bromo-1-phenylbutyl)-4-fluorobenzene
1-(4-Bromo-1-phenylbutyl)-4-fluorobenzene is an intermediate formed in the synthesis of Desfluoro Pimozide (D289865), an impurity of Pimozide (P447800). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C16H16BrF. US Biological Life Sciences.
Worldwide
Benperidol EP Impurity A HCl
Benperidol EP Impurity A HCl. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: Pimozide EP Impurity A HCl; 1-(piperidin-4-yl)-1,3-dihydro-2H-benzo[d]imidazol-2-one, hydrochloride. CAS No. 6961-12-2. Molecular Formula: C12H15N3O·HCl. Mole Weight: 253.73. Catalog: APB6961122.
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