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(2S, 3R, 4R, 5S)-3, 4, 5-Tris (phenylmethoxy)-2-[ (phenylmethoxy)methyl]-1-piperidineethanol is an intermediate in the synthesis of N-substituted iminosugar derivative, miglitol (M344200). Group: Biochemicals. Grades: Highly Purified. CAS No. 1445783-86-7. Pack Sizes: 1mg. Molecular Formula: C36H41NO5. US Biological Life Sciences.
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4-Piperidineethanol
4-Piperidineethanol. Group: Biochemicals. Alternative Names: 2-(4-Piperidyl)ethanol; 2-(Piperidin-4-yl)-1-ethanol; 2-(Piperidin-4-yl)ethanol; 4- (2-Hydroxyethyl) piperidine; NSC 93818. Grades: Highly Purified. CAS No. 622-26-4. Pack Sizes: 2.5g. Molecular Formula: C7H15NO, Molecular Weight: 129.199999999999. US Biological Life Sciences.
A negative allosteric modulator selective for NR2B containingnMDA receptors (IC50 = 1, >100, and >100uM for NR2B, NR2A, and NR2C, respectively). Also a potent ligand for alpha1 receptor (Ki = 0.013uM), one of the two types of unique non-opioid, non-phencyclidine brain alpha receptors. Blocks neuronal voltage-gated Ca2+. Group: Biochemicals. Grades: Highly Purified. CAS No. 119431-25-3. Pack Sizes: 10mg. US Biological Life Sciences.
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(R)-2-Piperidineethanol
(R)-2-Piperidineethanol. Group: Biochemicals. Alternative Names: (2R)-2-Piperidineethanol. Grades: Highly Purified. CAS No. 68419-38-5. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C7H15NO. US Biological Life Sciences.
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(S)-2-Piperidineethanol
Useful in preparation of a novel class of pyrazolopyrimidines as inhibitors of protein and checkpoint kinases useful in treatment and prophylaxis of HCV infection and other diseases such as cancer. Group: Biochemicals. Grades: Highly Purified. CAS No. 103639-57-2. Pack Sizes: 100mg. US Biological Life Sciences.
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1,3-Di(N-β-hydroxyethyl-4-piperidyl)-propane
1,3-Di(N-β-hydroxyethyl-4-piperidyl)-propane. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4'-(1,3-propanediyl)bis-1-piperidineethano;LABOTEST-BB LT00159833;1,3-BIS[1-(2-HYDROXYETHYL)-4-PIPERIDYL]PROPANE;1,3-DI(N-BETA-HYDROXYETHYL-4-PIPERIDYL)-PROPANE;4,4'-trimethylenebis(1-piperidineethanol);Bishydroxyethylpiperidylpropane;4,4'-(propane-1,3. Product Category: Heterocyclic Organic Compound. CAS No. 18073-84-2. Molecular formula: C17H34N2O2. Mole weight: 298.47. Purity: 0.96. IUPACName: 2-[4-[3-[1-(2-hydroxyethyl)piperidin-4-yl]propyl]piperidin-1-yl]ethanol. Canonical SMILES: C1CN(CCC1CCCC2CCN(CC2)CCO)CCO. Density: 1.01g/cm³. ECNumber: 241-981-7. Product ID: ACM18073842. Alfa Chemistry ISO 9001:2015 Certified.
1-Cbz-2-(2-hydroxy-ethyl)-piperidine
1-Cbz-2-(2-hydroxy-ethyl)-piperidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-CBZ-2-(2-HYDROXY-ETHYL)-PIPERIDINE, 2-(2-HYDROXY-ETHYL)-PIPERIDINE-1-CARBOXYLIC ACID BENZYL ESTER, 39945-50-1, 1-PIPERIDINECARBOXYLIC ACID, 2-(2-HYDROXYETHYL)-, PHENYLMETHYL ESTER, 885274-53-3, SureCN1841001, AGN-PC-00865P, CTK4I2139, 1-cbz-2-(2-hydroxyethyl)piperidine, AKOS009220707, AB19374, AG-F-41192, KB-152529, FT-0648180, BENZYL 2-(2-HYDROXYETHYL)PIPERIDINE-1-CARBOXYLATE, 1-Piperidinecarboxylicacid, 2-(2-hydroxyethyl)-, phenylmethyl ester, 1-PIPERIDINECARBOXYLIC ACID, 3-(2-HYDROXYETHYL)-, PHENYLMETHYL ESTER, 1-Benzyloxycarbonyl-2-piperidineethanol;2-(2-Hydroxyethyl)piperidine-1-carboxylic acid benzyl ester. Product Category: Heterocyclic Organic Compound. CAS No. 39945-50-1. Molecular formula: C15H21NO3. Mole weight: 263.3358. Purity: 0.97. IUPACName: benzyl 2-(2-hydroxyethyl)piperidine-1-carboxylate. Canonical SMILES: C1CCN(C(C1)CCO)C(=O)OCC2=CC=CC=C2. Density: 1.14g/cm³. Product ID: ACM39945501. Alfa Chemistry ISO 9001:2015 Certified.
1-Methylpiperidine-2-ethanol
1-Methylpiperidine-2-ethanol. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-methylpiperidine; 1-Methyl-2-piperidineethanol; NSC 75616. Grades: Highly Purified. CAS No. 533-15-3. Pack Sizes: 100mg, 250mg, 500mg, 1g, 2g. Molecular Formula: C8H17NO. US Biological Life Sciences.
Worldwide
1-Methylpiperidine-2-ethanol-d3
Labeled Thioridazine intermediate. Group: Biochemicals. Alternative Names: 2-(2-Hydroxyethyl)-1-methylpiperidine-d3; 1-Methyl-2-piperidineethanol-d3; NSC 75616-d3. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences.
4-Hydroxy-1-(2-hydroxyethyl)-2,2,6,6-tetramethylpiperidine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4-HYDROXY-1-HYDROXYETHYL-2,2,6,6-TETRAMETHYLPIPERIDINE;4-HYDROXY-2,2,6,6-TETRAMETHYL-1-PIPERIDINEETHANOL;N-(2'-HYDROXYETHYL)-4-HYDROXY-2,2,6,6-TETRAMETHYLPIPERIDINE;N-Hydroxyethyl tetraacetoneamino alcohol. Product Category: Heterocyclic Organic Compound. CAS No. 62421-70-9. Molecular formula: C11H23NO2. Mole weight: 201.31. Product ID: ACM62421709. Alfa Chemistry ISO 9001:2015 Certified. Categories: 52722-86-8.
alpha,alpha-Dimethylpiperidine-1-ethanol
alpha,alpha-Dimethylpiperidine-1-ethanol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: alpha,alpha-dimethylpiperidine-1-ethanol;SCH-1906;α,α-Dimethyl-1-piperidineethanol;1-Piperidineethanol, alpha,alpha-dimethyl-;alpha,alpha-Dimethyl-1-piperidineethanol;Brn 0001447;Einecs 236-092-6. Product Category: Heterocyclic Organic Compound. CAS No. 13150-40-8. Molecular formula: C9H19NO. Mole weight: 157.25326. Product ID: ACM13150408. Alfa Chemistry ISO 9001:2015 Certified.
Dinaciclib
Cyclin-dependent kinases (CDKs) are critical positive regulators of cell cycle progression and cellular transcription whose dysregulation can lead to the development of cancer. Dinaciclib inhibits CDK1, CDK2, CDK5, and CDK9 activity in vitro with IC50 values of 3, 1, 1, and 4 nM, respectively. Compared to the pan-CDK inhibitor flavopiridol, dinaciclib is an equally potent inhibitor of CDK1 and CDK9 but a 12-14-fold more potent inhibitor of CDK2 and CDK5. It has been shown to inhibit DNA synthesis by blocking thymidine incorporation in A2780 ovarian cancer cells with an IC50 value of 4nM. At 5mg/kg it prevents tumor growth by 50% in an A2780 ovarian carcinoma mouse xenograft model and is active against a broad spectrum of human tumor cell lines in vitro (IC50s = 7-17nM). Group: Biochemicals. Alternative Names: Sch 727965; (2S) -1- [3-Ethyl-7- [ [ (1-oxido-3-pyridinyl) methyl]amino]pyrazolo [1, 5-a]pyrimidin-5-yl]-2-piperidineethanol. Grades: Highly Purified. CAS No. 779353-01-4. Pack Sizes: 5mg. Molecular Formula: C21H28N6O2. US Biological Life Sciences.
Worldwide
Efinaconazole
Efinaconazole is a topical antifungal for onychomycosis. Group: Biochemicals. Alternative Names: (αR, βR)-α-(2,4-Difluorophenyl)- β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol; [R-(R*,R*)]-α-(2,4-Difluorophenyl)- β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidineethanol; KP 103; KP 103. Grades: Highly Purified. CAS No. 164650-44-6. Pack Sizes: 500mg, 1g. Molecular Formula: C??H??F?N?O, Molecular Weight: 348.39. US Biological Life Sciences.
Worldwide
Eliprodil
Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Synonyms: -(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL-82,0715; SL82,0715; SL 82,0715; SL-820715; SL820715; SL 820715; Eliprodil. Grades: 95%. CAS No. 119431-25-3. Molecular formula: C20H23ClFNO. Mole weight: 347.85.
Ifenprodil
Ifenprodil is an NMDA receptor antagonist and acts at the polyamine site. It is also an α2 adrenergic receptor ligand. It is selective for σ2 ligand over σ1 sites. It is used as a neuroprotective agent and peripheral vasodilator. Uses: Excitatory amino acid antagonists. Synonyms: 4-[2-(4-Benzylpiperidin-1-yl)-1-hydroxypropyl]phenol; (1R*,2S*)-erythro-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol; α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidineethanol; 1-Methyl-2-hydroxy-2-(4-hydroxyphenyl)ethyl-1-(4-benzylpiperidine); 2-(4-Benzylpiperidino)-1-(1-hydroxyphenyl)-1-propanol; RC 61-91. Grades: ≥99% by HPLC. CAS No. 23210-56-2. Molecular formula: C21H27NO2. Mole weight: 325.44.
Ifenprodil Hemitartrate.
Vasodilator (cerebral and peripheral). Group: Biochemicals. Alternative Names: α-(4-Hydroxyphenyl)- β-methyl-4-(phenylmethyl)-1-piperidineethanol (2R,3R)-2,3-Dihydroxybutanedioate. Grades: Highly Purified. CAS No. 23210-58-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
threo Ifenprodil hemitartrate
Threo Ifenprodil hemitartrate is the hemitartrate salt of threo ifenprodil, which is a NR2B subunit-selective NMDA receptor antagonist, as well as a potent σ receptor agonist. It inhibits the hERG potassium channel and shows antiarrhythmic activity in vivo. It also can be used for the treatment of Alzheimer's disease in combination with AMPA inhibitors. Synonyms: (1S*,2S*)-threo-2-(4-Benzylpiperidino)-1-(4-hydroxyphenyl)-1-propanol Hemitartrate; (αR,βR)-rel- α-(4-Hydroxyphenyl)-β-methyl-4-(phenylmethyl)-1-piperidineethanol (2R,3R)-2,3-Dihydroxybutanedioate (2:1). CAS No. 1312991-83-5. Molecular formula: C23H30NO5. Mole weight: 400.49.
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