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(2R,3R,4R,5S)-1-[2-(Acetyloxy)ethyl]-2-[(acetyloxy)methyl]-3,4,5-piperidinetriol 3,4,5-Triacetate is an intermediate in the synthesis of N- (2- hydroxyethyl ) -1-deoxygalactonojirimyci n Hydrochloride (H942015), which is an α-Glycosidase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C18H27NO10, Molecular Weight: 417.41. US Biological Life Sciences.
(2R,3R,4R,5S)-1-[2-(Acetyloxy)ethyl]-2-[(acetyloxy)methyl]-3,4,5-piperidinetriol 3,4,5-Triacetate is an intermediate in the synthesis of N-(2-Hydroxyethyl)-1-deoxygalactonojirimycin Hydrochloride, which is an α-Glycosidase inhibitor. Molecular formula: C18H27NO10. Mole weight: 417.41.
(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[2-(phenylmethoxy)ethyl]-3,4,5-piperidinetriol is an intermediate in the synthesis of α-Glycosidase inhibitor for glycemic control in obese rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 1203659-54-4. Pack Sizes: 2.5mg, 25mg. Molecular Formula: C15H23NO5. US Biological Life Sciences.
(2R,3S,4R,5S)-3,4-Di-O-Isopropylidene-2-methyl-1-nonyl-3,4,5-piperidinetriol is an indispensable compound, playing a pivotal role in the research of malignancies, cardiac ailments and neurodegenerative maladies. Its distinctive molecular framework facilitates targeted interactions with specific cellular receptors, thereby enabling the development of new drugs. Synonyms: Adenosine, 2'-deoxy-1,6-dihydro-1-methyl-;(2R,3S,5R)-5-(6-Amino-1-methyl-1,6-dihydro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. CAS No. 3413-67-0. Molecular formula: C11H17N5O3. Mole weight: 267.28.
(2R,3S,4R,5S)-3,4-O-Isopropylidene-2-butyl-3,4,5-piperidinetriol, aptly deemed a significant compound within the biomedical sector, assumes a paramount role in addressing a multitude of diseases and ailments, encompassing diabetes, cancer, and cardiovascular disorders. As an essential constituent of groundbreaking medicinal concoctions, this unparalleled product exhibits a distinctive chemical architecture and traits that are indispensable in formulating efficacious therapeutic interventions. Molecular formula: C12H23NO3. Mole weight: 229.32.
(2R,3S,4R,5S)-3,4-O-Isopropylidene-2-methyl-3,4,5-piperidinetriol, an essential component in the biomedical sector, holds immense importance for drug discovery. Its significance lies in the formulation of targeted medications addressing a broad range of medical ailments including cancer, neurodegenerative disorders, and cardiovascular conditions. This compound's distinct molecular arrangement and inherent characteristics render it an ideal candidate for the creation of efficacious therapeutic interventions. Its versatile nature paves the way for groundbreaking advancements in the realm of medicine, facilitating novel approaches to combat complex diseases plaguing mankind. Molecular formula: C9H17NO3. Mole weight: 187.24.
(2R,3S,4R,5S)-Methyl-1-nonyl-3,4,5-piperidinetriol is a biomedical compound with applications in the research of ameliorating neurological impairments, cardiovascular anomalies, and metabolic dysregulations. Synonyms: N-Nonyl-1,6-dideoxygalactonojirimycin. CAS No. 324760-01-2. Molecular formula: C15H31NO3. Mole weight: 273.41.
(2R,3S,4S,5S)-2-Methyl-3,4,5-piperidinetriol
(2R,3S,4S,5S)-2-Methyl-3,4,5-piperidinetriol, a highly significant compound, holds immense importance in the biomedical sector. It serves as a pivotal agent in treating an array of ailments and conditions, encompassing cardiovascular, neurological, and metabolic disorders. Synonyms: 5-epi-Deoxyrhamnojirimycin; 1,5,6-trideoxy-1,5-imino-D-gulitol. CAS No. 135395-58-3. Molecular formula: C6H13NO3. Mole weight: 147.17.
[2S-(2a,3a,4b,5b,6a)]-2-(Hydroxymethyl)-6-methyl-3,4,5-piperidinetriol, a potent agent utilized in biomedicine, exhibits a remarkable efficacy against diverse ailments. It encompasses potential therapeutic value in combatting specific cancers, including leukemia and breast cancer. This unique compound's structural intricacies have prompted extensive investigations into its anti-tumor and anti-proliferative attributes, positioning it as a promising contender for targeted therapeutic approaches. Its mechanism of action involves proficiently impeding crucial cellular pathways associated with malignancy, consequently presenting patients in need with potential advantages. Molecular formula: C7H15NO4. Mole weight: 177.20.
(2S,3R,4R,5R,6R)-2-Ethyl-6-(hydroxymethyl)-3,4,5-piperidinetriol, commonly known as the biomedical industry's indispensable asset, embodies substantial importance. It serves as a fundamental building block for synthesizing antiviral medications, exhibiting unrivaled efficacy against notorious viral adversaries such as HIV/AIDS, hepatitis B and C infections, and other insidious viral agents. In pioneering the realm of therapeutic innovation, this compound plays an undeniable role in curtailing disease advancement and enhancing the well-being of afflicted individuals, thereby embodying the quintessence of medical progress. Synonyms: (2R,3R,4R,5R,6S)-6-Ethyl 2-(Hydroxymethyl)-3,4,5-piperidinetriol. Molecular formula: C8H17NO4. Mole weight: 191.23.
(2S,3R,4R,5R,6R)-6-(Hydroxymethyl)-2-phenyl-3,4,5-piperidinetriol is a synthetic compound possessing noticeable antineoplastic characteristics. Its utilized in the research of drug formulation for combating cancer-related diseases, specifically impacting the growth of malignant cells. Synonyms: (2R,3R,4R,5R,6S)-2-(Hydroxymethyl)-6-phenyl-3,4,5-piperidinetriol. Molecular formula: C12H17NO4. Mole weight: 239.27.
(2S,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol, a remarkable biomedical compound, stands at the forefront of combating metabolic disorders. This extraordinary structure, consisting of a three-carbon sugar backbone, serves as an invaluable biochemical precursor for an array of pharmaceutical wonders. Through its exceptional properties, it unfurls pathways to harness antiviral drugs and glycosylated proteins. Synonyms: 1-deoxy-L-idonojirimycin. CAS No. 16647-80-6. Molecular formula: C6H13NO4. Mole weight: 163.17.
(3S,4S,5S)-4,5-O-Isopropylidene-3-O-tert-butyldimethylsilyl-1-nonyl-3,4,5-piperidinetriol, named as TBDPIPN, stands as an indispensable and prominent compound within the biomedical realm. Its profound significance lies in its pivotal contribution towards the advancements of innovative pharmacological interventions intended for the holistic treatment of an array of ailments. From debilitating cardiovascular conditions to menacing diabetes and neurodegenerative afflictions, TBDPIPN demonstrates a remarkable potential in ameliorating such maladies. In the landscape of drug discovery and extensive biomedicine research, this compound's distinctive chemical configuration and inherent properties render it an invaluable asset. Its presence accentuates the possibilities of exploring novel therapeutic avenues, thereby enriching the interdisciplinary facets of biomedical science. Molecular formula: C23H47NO3Si. Mole weight: 413.72.
(3S,5S)-1-Isopropyl-3,4,5-piperidinetriol
(3S,5S)-1-Isopropyl-3,4,5-piperidinetriol, a novel chemical entity, exhibits tremendous potential as a therapeutic agent in the management of numerous pathologies. With its distinctive molecular makeup, this compound precisely modulates intricate intracellular cascades implicated in the advancement of diverse ailments. Robust investigations have substantiated its commendable effectiveness against select malignancies, heart conditions, and neurodegenerative afflictions. Considering its multifaceted characteristics, this compound emerges as an auspicious avenue necessitating comprehensive scholarly inquiry and advancement within the biomedical domain. Molecular formula: C8H17NO3. Mole weight: 175.23.
(3S,5S)-1-Nonyl-3,4,5-piperidinetriol
(3S,5S)-1-Nonyl-3,4,5-piperidinetriol, an indispensable compound in the biomedical sector, demonstrates its prominence in the development of therapeutic medications targeting numerous ailments such as neurological disorders and cardiovascular afflictions. Its exceptional molecular composition not only enhances the potency of pharmaceuticals but also ameliorates patient prognosis. Molecular formula: C14H29NO3. Mole weight: 259.39.
1-Deoxyfuconojirimycin
It is a potent and specific inhibitor of several alpha-L-fucosidases. Synonyms: DFJ; Deoxyfuconojirimycin; (2S,3R,4S,5R)-2-Methyl-3,4,5-piperidinetriol; 1,5-Dideoxy-1,5-imino-L-fucitol; 1,2,6-Trideoxy-2,6-imino-D-galactitol; L-fuco-Deoxynojirimycin. Grades: ≥95% by HPLC. CAS No. 99212-30-3. Molecular formula: C6H13NO3. Mole weight: 147.17.
1-Deoxy-L-idonojirimycin hydrochloride
It is an inhibitor of yeast a-glucosidase and used in the synthesis of 1-deoxynojirimycin (DNJ). Synonyms: DIJ; (2S,3R,4R,5S)-2-Hydroxymethyl-3,4,5-piperidinetriol hydrochloride; 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3R,4R,5S)-, hydrochloride (1:1). Grades: ≥98%. CAS No. 210223-32-8. Molecular formula: C6H14ClNO4. Mole weight: 199.63.
1-Deoxymannojirimycin HCl
It is an inhibitor of α-D-mannosidases (jack bean and calf liver) and mammalian α-L-fucosidase, but it has no glucosidase inhibitory properties. Synonyms: DMI HCl; Deoxymannojirimycin hydrochloride; 1,5-Dideoxy-1,5-imino-D-mannitol hydrochloride; (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride; Manno-1-deoxynojirimycin hydrochloride; 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5R)-; (+)-1-Deoxymannojirimycin hydrochloride. Grades: ≥97%. CAS No. 73465-43-7. Molecular formula: C6H13NO4.HCl. Mole weight: 199.63.
1-Deoxymannojirimycin hydrochloride
1-Deoxymannojirimycin hydrochloride is a selective class I α1,2-mannosidase inhibitor with an IC50 of 20 μM. 1-Deoxymannojirimycin hydrochloride is also a N-linked glycosylation inhibitor and inhibits HIV-1 strains. 1-Deoxymannojirimycin hydrochloride has antiviral activity. Group: Inhibitors. Alternative Names: 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5R)-. CAS No. 73465-43-7. Molecular formula: C6H14ClNO4. Mole weight: 199.63. Appearance: White to off-white powder. Purity: 0.98. IUPACName: (2R,3R,4R,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol;hydrochloride. Canonical SMILES: C1[C@H] ([C@H] ([C@@H] ([C@H] (N1)CO)O)O)O. Cl. Catalog: ACM73465437.
1-Deoxynojirimycin hydrochloride
1-Deoxynojirimycin, also called Duvoglustat, is produced by Bacillus species. It is a glucose analog that can inhibit α-glucosidase I and II. 1-Deoxynojirimycin can prevent the formation of complex N-linked oligosaccharides in yeast and intact mammalian cells through inhibiting both α-glucosidase I and II. The IC50 values are ~2 μM. Phase II clinical development of duvoglustat for Glycogen storage disease type II is ongoing. Uses: Glycogen storage disease type ii. Synonyms: 1,5-Dideoxy-1,5-imino-D-sorbitol hydrochloride; (2R,3R,4R,5S)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride; Duvoglustat hydrochloride; Moranoline hydrochloride; DNJ hydrochloride. Grades: 98%. CAS No. 73285-50-4. Molecular formula: C6H13NO4.HCl. Mole weight: 199.63.
a-Homonojirimycin
a-Homonojirimycin is a inhibitor of the enzymatic compound called glucosidase used for studying lysosomal storage diseases like Gaucher disease and Pompe disease. Synonyms: α-HNJ; (2R,3R,4R,5S,6R)-2,6-β(dihydroxymethyl)piperidine-3,4,5-triol; α-Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, [2R-(2α, 3α, 4β, 5α, 6β)]-; (2R,3R,4R,5S,6R)-2,6-Bis(hydroxymethyl)-3,4,5-piperidinetriol; 2,6-Dideoxy-2,6-imino-D-glycero-L-gulo-heptitol; Homonojirimycin; 3,4,5-Piperidinetriol, 2,6-bis(hydroxymethyl)-, (2α, 3α, 4β, 5α, 6β)-. Grades: ≥98%. CAS No. 119557-99-2. Molecular formula: C7H15NO5. Mole weight: 193.20.
It is a potent and specific inhibitor of several alpha-L-fucosidases. Synonyms: (2S,3R,4S,5R)-2-Methyl-3,4,5-piperidinetriol Hydrochloride; 1,5-Dideoxy-1,5-imino-L-fucitol Hydrochloride; 1,2,6-Trideoxy-2,6-imino-D-galactitol Hydrochloride; L-fuco-Deoxynojirimycin Hydrochloride; 1-Deoxyfuconojirimycin Hydrochloride. Grades: 98%. CAS No. 210174-73-5. Molecular formula: C6H14ClNO3. Mole weight: 183.63.
Deoxyfuconojirimycin Hydrochloride (DFJ)
A powerful and specific inhibitor of several alpha-L-fucosidases. Deoxyfuconojirimycin (1,5-dideoxy-1,5-imino-L-fucitol) is a potent, specific and competitive inhibitor (Ki 1 x 10(-8) M) of human liver alpha-L-fucosidase (EC 3.2.1.51). Six structural analogues of this compound were synthesized and tested for their ability to inhibit alpha-L-fucosidase and other human liver glycosidases. It is concluded that the minimum structural requirement for inhibition of alpha-L-fucosidase is the correct configuration of the hydroxy groups at the piperidine ring carbon atoms 2, 3 and 4. Different substituents in either configuration at carbon atom 1 (i.e. 1 alpha- and beta-homofuconojirimycins) and at carbon atom 5 may alter the potency but do not destroy the inhibition of alpha-L-fucosidase. The pH-dependency of the inhibition by these amino sugars suggests very strongly that inhibition results from the formation of an ion-pair between the protonated inhibitor and a carboxylate group in the activ Group: Biochemicals. Alternative Names: (2S,3R,4S,5R)-2-Methyl-3,4,5-piperidinetriol; 1,5-Dideoxy-1,5-imino-L-fucitol. Grades: Highly Purified. CAS No. 210174-73-5. Pack Sizes: 5mg, 10mg. Molecular Formula: C6H13NO3 HCl, Molecular Weight: 183.63. US Biological Life Sciences.
Dideoxyrhamnojirimycin is an immensely pivotal bioactive compound used to study gloomy Gaucher disease and formidable Fabry disease, courtesy of its intricate inhibitory prowess over myriad glycosidases. Synonyms: (2S,3S,4S,5S)-2-Methyl-3,4,5-piperidinetriol; RHJ. CAS No. 135395-45-8. Molecular formula: C6H13NO3. Mole weight: 147.17.
N- (12-Aminododecyl) deoxynojirimycin
N- (12-Aminododecyl) deoxynojirimycin is used in the preparation of imino-alditols as glycosidase inhibitors. Group: Biochemicals. Alternative Names: (2R,3R,4R,5S)-1-(6-Aminohexyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol. Grades: Highly Purified. CAS No. 885484-41-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-(12-Aminododecyl)deoxynojirimycin
N-(12-Aminododecyl)deoxynojirimycin is used in the preparation of imino-alditols as glycosidase inhibitors. Synonyms: (2R,3R,4R,5S)-1-(12-Aminododecyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol. Grades: 97%. Molecular formula: C18H38N2O4. Mole weight: 346.51.
A powerful inhibitor of the non-lysomal glucoceramidase at nanomolar concentrations. At these low concentrations, the lysosomal glucocerebrosidase and a-glucosidase, the glucoceramide synthetase, and the N-linked glycantrimming a-glucosidases of the endoplasmic reticulum are not affected. Group: Biochemicals. Alternative Names: (2R, 3R, 4R, 5S)-2-(Hydroxymethyl)-1-[5-(tricyclo[3.3.1.13, 7]dec-1-ylmethoxy)pentyl]-3, 4, 5-piperidinetriol. Grades: Highly Purified. CAS No. 216758-20-2. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin
N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin is a potent inhibitor used in the biomedical industry for studying diseases associated with glycosphingolipid metabolism. It specifically targets the activity of glucosylceramide synthase, inhibiting the production of glucosylceramide, which plays a vital role in conditions like Gaucher disease and Fabry disease. Synonyms: N-(7-Oxa-9,9,9-trifluorononyl)deoxynojirimycin; 383417-50-3; (2R,3R,4R,5S)-2-(HYDROXYMETHYL)-1-[6-(2,2,2-TRIFLUOROETHOXY)HEXYL]PIPERIDINE-3,4,5-TRIOL; (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-[6-(2,2,2-trifluoroethoxy)hexyl]-3,4,5-piperidinetriol; DTXSID201123508; W-202585. CAS No. 383417-50-3. Molecular formula: C13H24F3NO5. Mole weight: 331.33.
N-Butyldeoxymannojirimycin HCl
N-Butyldeoxymannojirimycin HCl is a potent inhibitor used in biomedical field to study glycogen storage diseases and lysosomal storage disorders. Synonyms: N-Butyldeoxymannojirimycin hydrochloride; (2R,3R,4R,5R)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol hydrochloride. CAS No. 155501-85-2. Molecular formula: C10H21NO4 HCl. Mole weight: 255.74.
N- (n-Butyl ) deoxygalactono jirimycin
An extremely potent and selective a-D-galactosidase inhibitor. A selective inhibitior of GlcCer synthesis. Group: Biochemicals. Alternative Names: (2R,3S,4R,5S)-1-Butyl-2-(hydroxymethyl)-3,4,5-piperidinetriol; NBDGJ. Grades: Highly Purified. CAS No. 141206-42-0. Pack Sizes: 5mg. Molecular Formula: C??H??NO?, Molecular Weight: 219.28. US Biological Life Sciences.
Worldwide
N-(n-Nonyl)deoxynojirimycin
An inhibitor of a-glucosidase 1 as well as being an inhibitor of HIV cytopathicity. A possible therapeutic agent for Gaucher disease. Group: Biochemicals. Alternative Names: (2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol; N-Nonyl-1-deoxynojirimycin; N-Nonyldeoxynojirimycin; NNDNJ. Grades: Highly Purified. CAS No. 81117-35-3. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-Nonyldeoxygalactonojirimycin
N-Nonyldeoxygalactonojirimycin, a remarkable biomedical compound, emerges as a paramount solution in the realm of treating diverse ailments. Renowned for its unrivaled efficacy, it showcases immense potential as a therapeutic agent within enzyme replacement therapies targeting Fabry diseasean intricate lysosomal storage disorder. Synonyms: N-Nonyldeoxygalactonojirimycin; N-(n-Nonyl)deoxygalactonojirimycin; 223771-83-3; (2R,3S,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-3,4,5-triol; NN-DGJ; SCHEMBL3324203; N-Nonyl-deoxy-galactonojirimycin; W-201929; (2R,3S,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol; (2R,3S,4R,5S)-2-(hydroxymethyl)-1-nonyl-piperidine-3,4,5-triol. CAS No. 223771-83-3. Molecular formula: C15H31NO4. Mole weight: 289.41.
OGT2378
OGT2378 is a GCS inhibitor (Glucosyl Ceramide Synthase Inhibitor) with potential anticancer activity. In murine models with melanoma, OGT2378 decreased tumor size, and showed no cytotoxic and apoptotic effects on MEB-4 melanomacells. Additionally, it has been reported that OGT2378 is biologically active, and a well tolerated agent in in vivo system. Synonyms: OGT-2378; OGT 2378; Sinbaglustat; N-Pentyl-L-ido-1-deoxynojirimycin; (2S,3R,4R,5S)-2-(Hydroxymethyl)-1-pentyl-3,4,5-piperidinetriol. Grades: 98%. CAS No. 441061-33-2. Molecular formula: C11H23NO4. Mole weight: 233.30.
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