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Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. IC50: HepG2=5.8 nM. Synonyms: Zypitamag; (3R,5S,6E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid; (3R,5S)-3,5-Dihydroxy-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-6-heptenoic acid; Itavastatin; Livalo; NK 104; itavastatinn; NK-104; NK104; P 872441; P-872441; P872441. Grades: > 98%. CAS No. 147511-69-1. Molecular formula: C25H24FNO4. Mole weight: 421.46.
Pitavastatin
Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104. CAS No. 147511-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0144A.
Pitavastatin
Pitavastatin. Uses: Designed for use in research and industrial production. CAS No. 147526-32-7. Molecular formula: C25H24FNO4. Mole weight: 421.46. Purity: 0.98. Product ID: ACM147526327. Alfa Chemistry ISO 9001:2015 Certified.
Pitavastatin 1-Phenylethylamide
Pitavastatin 1-Phenylethylamide is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity. Molecular formula: C33H33FN2O3. Mole weight: 524.62.
Pitavastatin 3-Ether Glucuronide
Pitavastatin 3-Ether Glucuronide. Group: Biochemicals. Alternative Names: (1R,3S,4E)-1-(Carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. CAS No. 224320-11-0. Pack Sizes: 1mg. Molecular Formula: C31H32FNO10, Molecular Weight: 597.58. US Biological Life Sciences.
Worldwide
Pitavastatin 3-Ether Glucuronide
Pitavastatin 3-Ether Glucuronide is one of pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: β-D-Glucopyranosiduronic acid, (1R,3S,4E)-1-(carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl; (1R,3S,4E)-1-(Carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl β-D-Glucopyranosiduronic Acid; (2R,4S,5E)-1-Carboxy-6-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-4-hydroxy-5-hexen-2-yl β-D-glucopyranosiduronic acid. Grades: ≥95%. CAS No. 224320-11-0. Molecular formula: C31H32FNO10. Mole weight: 597.58.
Pitavastatin 3-O-Glucuronide
A metabolite of Pitavastatin which is a Hydroxymethylglutaryl-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C31H31FNO10. Mole weight: 596.58.
Pitavastatin 3-Oxo Acid
A metabolite of Pitavastatin which causes atherosclerosis regression in humans with subclinical carotid atherosclerosis. Grades: > 95%. Molecular formula: C25H22FNO4. Mole weight: 419.46.
Pitavastatin 3-Oxo Ethyl Ester
A metabolite of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: (E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Ethyl Ester. Grades: > 95%. CAS No. 148901-69-3. Molecular formula: C27H26FNO4. Mole weight: 447.51.
Pitavastatin 3-Oxo Sodium
A metabolite of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Synonyms: 3-Oxo Pitavastatin Sodium; Sodium (5S, 6E)-7-[2-cyclopropyl-4-(4-flurophenyl)-3- quinolinyl]-5-hydroxy-3-oxo-6-heptenoate. Grades: > 95%. Molecular formula: C25H21FNO4.Na. Mole weight: 441.44.
Pitavastatin 3S, 5R-Isomer Sodium
A metabolite of Pitavastatin which is a potent HMG-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C25H23FNO4.Na. Mole weight: 443.45.
Pitavastatin 3S, 5S-Isomer Sodium
A metabolite of Pitavastatin which is a member of the blood cholesterol lowering medication class of statins. Grades: > 95%. Molecular formula: C25H23FNO4.Na. Mole weight: 443.45.
Pitavastatin 5-Oxo Impurity
An impurity of Pitavastatin which induces plaque regression and elevates HDL-cholesterol levels. Synonyms: (3R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic Acid. Grades: > 95%. CAS No. 222306-15-2. Molecular formula: C25H22FNO4. Mole weight: 419.46.
Pitavastatin 5-Oxo Impurity Calcium Salt
An impurity in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: (3R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic acid calcium salt (2:1). CAS No. 2180095-22-9. Molecular formula: C50H42CaF2N2O8. Mole weight: 876.9.
Pitavastatin (5R)-Oxo Impurity
An impurity of Pitavastatin which inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Grades: > 95%. Molecular formula: C26H24FNO4. Mole weight: 433.48.
Pitavastatin (5S)-Oxo Impurity
A metabolite of Pitavastatin which is a potent HMG-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C26H24FNO4. Mole weight: 433.48.
Pitavastatin 8-Hydroxy Impurity
Pitavastatin Acyl Glucuronide
A metabolite of Pitavastatin which is a Hydroxymethylglutaryl-CoA reductase inhibitor. Synonyms: 1-[(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate] β-D-Glucopyranuronic Acid. Grades: > 95%. CAS No. 574752-66-2. Molecular formula: C31H32FNO10. Mole weight: 597.6.
Pitavastatin Acyl Glucuronide
Pitavastatin Acyl Glucuronide. Group: Biochemicals. Alternative Names: 1-[(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate] β-D-Glucopyranuronic acid. Grades: Highly Purified. CAS No. 574752-66-2. Pack Sizes: 500ug. Molecular Formula: C31H32FNO10, Molecular Weight: 597.58. US Biological Life Sciences.
Worldwide
Pitavastatin calcium
Pitavastatin calcium. Group: Biochemicals. Grades: Purified. CAS No. 147526-32-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104 hemicalcium; Pitavastatin hemicalcium. CAS No. 147526-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0144.
Pitavastatin calcium salt
1g Pack Size. Group: Bioactive Small Molecules, Organics. Formula: C50H46CaF2N2O8. CAS No. 147526-32-7. Prepack ID 58656411-1g. Molecular Weight 881. See USA prepack pricing.
Pitavastatin-d5 Lactone
A labeled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells. Group: Biochemicals. Alternative Names: (4R, 6S) -6- [ (1E) -2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6 β (E) ] ] -6- [2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5 (lactone); Nisvastatin-d5; P 872441-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pitavastatin-d5 Sodium Salt
Labeled Pitavastatin. A HMG CoA reductase inhibitor. An antilipemic. Group: Biochemicals. Alternative Names: (3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; (+)-(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; NK 104-d5 Sodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pitavastatin Defuoro Impurity Calcium Salt
An impurity of Pitavastatin which inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin Calcium Salt; CS-0164801; 1258947-30-6; monocalcium mono((3R,5S,E)-7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate)? (Pitavastatin Impurity pound(c). Grades: > 95%. CAS No. 1258947-30-6. Molecular formula: C50H48N2O8.Ca. Mole weight: 845.03.
Pitavastatin Impurity 10
An impurity of Pitavastatin which has a potent cholesterol-lowering action. Grades: > 95%. Molecular formula: C13H22O5. Mole weight: 258.32.
Pitavastatin Impurity 10
Pitavastatin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one. CAS No. 141750-63-2. Molecular formula: C25H22FNO3. Mole weight: 403.45. Catalog: APB141750632.
Pitavastatin Impurity 11
An impurity of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Grades: > 95%. Molecular formula: C33H33FN2O3. Mole weight: 524.64.
Pitavastatin Impurity 12
An impurity of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Grades: > 95%. Molecular formula: C27H28FNO4.C8H11N. Mole weight: 570.71.
Pitavastatin Impurity 13
Pitavastatin Impurity 13 (Pitavastatin 2,4,6-Triene Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 2,4,6-Triene Impurity. Grades: > 95%. CAS No. 2086271-67-0. Molecular formula: C25H20FNO2. Mole weight: 385.43.
Pitavastatin Impurity 14
Pitavastatin Impurity 14 (Pitavastatin 2-Fluoro Isomer) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 2-Fluoro Isomer. Grades: > 95%. Molecular formula: C25H24FNO4. Mole weight: 421.46.
Pitavastatin Impurity 15
Pitavastatin Impurity 15 (Pitavastatin 4,6-Diene Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3S,4E,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3-hydroxyhepta-4,6-dienoic acid; Pitavastatin 4,6-Diene Impurity. Molecular formula: C25H22FNO3. Mole weight: 403.44.
Pitavastatin Impurity 16
Pitavastatin Impurity 16 (Pitavastatin 4-Desfluoro 4-Hydroxy Impurity) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin 4-Desfluoro 4-Hydroxy Impurity. Grades: > 95%. Molecular formula: C25H25NO5. Mole weight: 419.47.
Pitavastatin Impurity 18
An impurity of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: Pitavastatin N-Oxide. Grades: > 95%. Molecular formula: C25H24FNO5. Mole weight: 437.47.
Pitavastatin Impurity 18 Sodium Salt
Pitavastatin Impurity 18 Sodium Salt (Pitavastatin N-Oxide Sodium Salt) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-1-oxido-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid, sodium salt (1:1); Pitavastatin N-Oxide Sodium Salt. CAS No. 2276678-27-2. Molecular formula: C25H23FNO5Na. Mole weight: 459.44.
Pitavastatin Impurity 19
An impurity of Pitavastatin which causes atherosclerosis regression in humans with subclinical carotid atherosclerosis. Synonyms: Pitavastatin Epoxide Impurity. Grades: > 95%. Molecular formula: C25H24FNO5. Mole weight: 437.47.
Pitavastatin Impurity 19 Sodium Salt (Mixture of Diastereomers)
Pitavastatin Impurity 19 Sodium Salt (Mixture of Diastereomers) is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S)-5-(3-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)oxiran-2-yl)--dihydroxyhept-6-enoic acid. Molecular formula: C25H23FNO5Na. Mole weight: 459.44.
Pitavastatin Impurity 1 Calcium Salt
Pitavastatin Impurity 1 Calcium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.49.
Pitavastatin Impurity 1 (PP-1)
An impurity of Pitavastatin which is a Hydroxymethylglutaryl-CoA reductase inhibitor. Grades: > 95%. Molecular formula: C25H24FNO4. Mole weight: 421.47.
Pitavastatin Impurity 2
(3R,5S)-5-(6-Cyclopropyl-10-fluorobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid; Pitavastatin Impurity 2 (PP-2). Grades: 94%. CAS No. 1187966-93-3. Molecular formula: C25H22FNO4. Mole weight: 419.44.
Pitavastatin Impurity 20
Pitavastatin Impurity 20 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Uses: A hmg-coa reductase inhibitor intermediate. Synonyms: (4R-cis)-6-Chloromethyl-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester; tert-butyl syn-(3R,5S)-6-chloro-3,5-(isopropylidenedioxy)-hexanoate; (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid; t-butyl (4R-cis)-6-(chloromethyl)-2,2-dimethyl-1,3-dioxan-4-ylacetate; (4R,6S)-6-(Chloromethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester. Grades: 96%. CAS No. 154026-94-5. Molecular formula: C13H23ClO4. Mole weight: 278.77.
Pitavastatin Impurity 22
Pitavastatin Impurity 22 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H36FNO4. Mole weight: 517.63.
Pitavastatin Impurity 38
Pitavastatin Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-((Z)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 154170-27-1. Molecular formula: C32H36FNO4. Mole weight: 517.63. Catalog: APB154170271.
Pitavastatin Impurity 5
Pitavastatin Impurity 5 is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: t-Butyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-isopropylidenedioxy-6-heptenoate; (4R,6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic acid tert-butyl ester; Pitavastatin Impurity 21. Grades: 98%. CAS No. 147489-06-3. Molecular formula: C32H36FNO4. Mole weight: 517.63.
Pitavastatin Impurity 59
Pitavastatin Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4S,6R)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 1044518-75-3. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB1044518753.
Pitavastatin Impurity 6
An impurity of Pitavastatin which induces plaque regression and elevates HDL-cholesterol levels. Grades: > 95%. Molecular formula: C32H36FNO4. Mole weight: 517.65.
Pitavastatin Impurity 62
Pitavastatin Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 154026-95-6. Molecular formula: C15H26O6. Mole weight: 302.36. Catalog: APB154026956.
Pitavastatin Impurity 63
Pitavastatin Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 124655-09-0. Molecular formula: C13H24O5. Mole weight: 260.33. Catalog: APB124655090.
Pitavastatin Impurity 65
Pitavastatin Impurity 65. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((bromotriphenylphosphoranyl)methyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline. CAS No. 154057-58-6. Molecular formula: C37H30BrFNP. Mole weight: 618.52. Catalog: APB154057586.
Pitavastatin Impurity 68
Pitavastatin Impurity 68. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline. CAS No. 154057-56-4. Molecular formula: C19H15BrFN. Mole weight: 356.23. Catalog: APB154057564.
Pitavastatin Impurity 7
An impurity of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Grades: > 95%. Molecular formula: C32H36FNO4. Mole weight: 517.65.
Pitavastatin Impurity 74
Pitavastatin Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 167934-30-7. Molecular formula: C29H30FNO4. Mole weight: 475.55. Catalog: APB167934307.
Pitavastatin Impurity 8
An impurity of Pitavastatin which lowers both total cholesterol and low density lipoprotein cholesterol in animals and humans. Synonyms: 3,5-Dideoxy-2,4-O-(1-methylethylidene)-D-erythro-hexuronic Acid 1,1-Dimethylethyl Ester. Grades: > 95%. CAS No. 1044518-75-3. Molecular formula: C13H22O5. Mole weight: 258.32.
Pitavastatin Impurity 9
An impurity of Pitavastatin which causes atherosclerosis regression in humans with subclinical carotid atherosclerosis. Grades: > 95%. Molecular formula: C13H22O5. Mole weight: 258.32.
Pitavastatin Impurity 9
Pitavastatin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 167073-19-0. Molecular formula: C27H28FNO4. Mole weight: 449.52. Catalog: APB167073190.
Pitavastatin lactone
Pitavastatin lactone is a major metabolite of Pitavastatin in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 141750-63-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125643.
Pitavastatin Lactone
A metabolite of Pitavastatin which is a member of the blood cholesterol lowering medication class of statins. Uses: Hydroxymethylglutaryl-coa reductase inhibitors. Synonyms: Itavastatin Lactone; (4R,6S,E)-6-[2-[2-Cyclopropyl-4-(4-fluorophenyl) quinolin-3-yl] vinyl] tetrahydro-4-hydroxypyran-2-one. Grades: > 95%. CAS No. 141750-63-2. Molecular formula: C25H22FNO3. Mole weight: 403.46.
Pitavastatin Methyl Ester
An impurity of Pitavastatin which is a member of the blood cholesterol lowering medication class of statins. Synonyms: Pitavastatin Methyl Ester ; (3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoic acid methyl ester. Grades: > 95%. CAS No. 849811-78-5. Molecular formula: C26H26FNO4. Mole weight: 435.5.
(3R, 5R)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Grades: > 95%. CAS No. 254452-96-5. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01.
(3S,5R)-Pitavastatin Calcium
A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86.
(3S,5R)-tert-Butyl Pitavastatin
A metabolite of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Grades: > 95%. Molecular formula: C29H32FNO4. Mole weight: 477.58.
(3S,5S)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which has a potent cholesterol-lowering action. Synonyms: 3-Epi-NK-104; Pitavastatin 3S,5S-Isomer Calcium Salt; (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-92-1. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.5.
4-Dehydroxy-3-dehydro-pitavastatin-d5 Lactone
A labeled metabolite of Pitavastatin in humans and monkeys. Group: Biochemicals. Alternative Names: (6S) -6- [ (1E) -2- [2-Cyclopropyl-d5-4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-2H-pyran-2-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5-Oxo Pitavastatin
5-Oxo Pitavastatin. Group: Biochemicals. Alternative Names: (3R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic Acid. Grades: Highly Purified. CAS No. 222306-15-2. Pack Sizes: 2.5mg. Molecular Formula: C25H22FNO4, Molecular Weight: 419.44. US Biological Life Sciences.
Worldwide
8-Hydroxy Pitavastatin
8-Hydroxy Pitavastatin is one of Pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-8-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; (3R,5S,6E)-7-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; Pitavastatin 8'-Hydroxy Impurity. Grades: ≥90%. CAS No. 224320-09-6. Molecular formula: C25H24FNO5. Mole weight: 437.46.
Rosuvastatin Impurity 61 (Pitavastatin Impurity 64). Uses: For analytical and research use. Group: Impurity standards. CAS No. 124752-23-4. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB124752234.
tert-Buthyl Pitavastatin
tert-Buthyl Pitavastatin is the metabolite of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 586966-54-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-135384.
tert-Butyl Pitavastatin
An impurity of Pitavastatin which causes atherosclerosis regression in humans with subclinical carotid atherosclerosis. Synonyms: tert-Butyl pitavastatin; 586966-54-3; tert-Buthyl Pitavastatin; 615263-53-1; tert-butyl (E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate. Grades: > 95%. CAS No. 586966-54-3. Molecular formula: C29H32FNO4. Mole weight: 477.58.
(Z)-Pitavastatin Calcium Salt
An impurity of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Synonyms: (Z)-Pitavastatin Calcium Salt; 1159588-21-2; (Z,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate. Grades: > 95%. CAS No. 1159588-21-2. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01.
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