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Pitavastatin (NK-104) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104. CAS No. 147511-69-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-B0144A.
Pitavastatin
Pitavastatin. Uses: Designed for use in research and industrial production. CAS No. 147526-32-7. Molecular formula: C25H24FNO4. Mole weight: 421.46. Purity: 0.98. Product ID: ACM147526327. Alfa Chemistry ISO 9001:2015 Certified.
Pitavastatin 3-Ether Glucuronide
Pitavastatin 3-Ether Glucuronide. Group: Biochemicals. Alternative Names: (1R,3S,4E)-1-(Carboxymethyl)-5-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-4-penten-1-yl β-D-Glucopyranosiduronic Acid. Grades: Highly Purified. CAS No. 224320-11-0. Pack Sizes: 1mg. Molecular Formula: C31H32FNO10, Molecular Weight: 597.58. US Biological Life Sciences.
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Pitavastatin Acyl Glucuronide
Pitavastatin Acyl Glucuronide. Group: Biochemicals. Alternative Names: 1-[(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoate] β-D-Glucopyranuronic acid. Grades: Highly Purified. CAS No. 574752-66-2. Pack Sizes: 500ug. Molecular Formula: C31H32FNO10, Molecular Weight: 597.58. US Biological Life Sciences.
Worldwide
Pitavastatin calcium
Pitavastatin calcium. Group: Biochemicals. Grades: Purified. CAS No. 147526-32-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Pitavastatin calcium
Pitavastatin calcium is a novel member of the medication class of statins. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt; Flovas; Livalo; NK 104; NK 104 (acid); Pitava 1; Pitavastatin Hemicalcium; Pitavastatin Calcium Salt; calcium (E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Nisvastatin; NK-104; P 872441; P-872441; P872441. Grade: 96%. CAS No. 147526-32-7. Molecular formula: C50H46CaF2N2O8. Mole weight: 880.98.
Pitavastatin Calcium
Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104 hemicalcium; Pitavastatin hemicalcium. CAS No. 147526-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0144.
Pitavastatin calcium salt
1g Pack Size. Group: Bioactive Small Molecules, Organics. Formula: C50H46CaF2N2O8. CAS No. 147526-32-7. Prepack ID 58656411-1g. Molecular Weight 881. See USA prepack pricing.
Pitavastatin-[d4] Calcium Salt
Pitavastatin-[d4] Calcium Salt, is the labelled analogue of Pitavastatin. Pitavastatin is a member of the blood cholesterol lowering medication class of statins. It is an inhibitor of HMG-CoA reductase. Synonyms: Pitavastatin D4 Calcium Salt. Grade: > 95%. Molecular formula: C50H38D8F2N2O8Ca. Mole weight: 889.03.
Pitavastatin-d5 Lactone
A labeled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells. Group: Biochemicals. Alternative Names: (4R, 6S) -6- [ (1E) -2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6 β (E) ] ] -6- [2- [2- (Cyclopropyl-d5) -4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5 (lactone); Nisvastatin-d5; P 872441-d5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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Pitavastatin-d5 Sodium Salt
Labeled Pitavastatin. A HMG CoA reductase inhibitor. An antilipemic. Group: Biochemicals. Alternative Names: (3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; (+)-(3R,5S,6E)-7-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolyl]-3,5-dihydroxy-6-heptenoic Acid Sodium Salt; NK 104-d5 Sodium Salt. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Pitavastatin ethyl ester
Pitavastatin Ethyl Ester is used as a reactant in the preparation of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (E)-(3R,5S)-7-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester; (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Ethyl Ester; 3R,5S-DOLE; Pitavastatin Impurity 17; 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, ethyl ester, (3R,5S,6E)-. Grade: ≥95%. CAS No. 167073-19-0. Molecular formula: C27H28FNO4. Mole weight: 449.51.
Pitavastatin Impurity 10
Pitavastatin Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-4-hydroxytetrahydro-2H-pyran-2-one. CAS No. 141750-63-2. Molecular formula: C25H22FNO3. Mole weight: 403.45. Catalog: APB141750632.
Pitavastatin Impurity 38
Pitavastatin Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-((Z)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 154170-27-1. Molecular formula: C32H36FNO4. Mole weight: 517.63. Catalog: APB154170271.
Pitavastatin Impurity 59
Pitavastatin Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4S,6R)-6-formyl-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 1044518-75-3. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB1044518753.
Pitavastatin Impurity 62
Pitavastatin Impurity 62. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(acetoxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 154026-95-6. Molecular formula: C15H26O6. Mole weight: 302.36. Catalog: APB154026956.
Pitavastatin Impurity 63
Pitavastatin Impurity 63. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: tert-butyl 2-((4R,6S)-6-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 124655-09-0. Molecular formula: C13H24O5. Mole weight: 260.33. Catalog: APB124655090.
Pitavastatin Impurity 65
Pitavastatin Impurity 65. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((bromotriphenylphosphoranyl)methyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline. CAS No. 154057-58-6. Molecular formula: C37H30BrFNP. Mole weight: 618.52. Catalog: APB154057586.
Pitavastatin Impurity 68
Pitavastatin Impurity 68. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline. CAS No. 154057-56-4. Molecular formula: C19H15BrFN. Mole weight: 356.23. Catalog: APB154057564.
Pitavastatin Impurity 74
Pitavastatin Impurity 74. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: methyl 2-((4R,6S)-6-((E)-2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate. CAS No. 167934-30-7. Molecular formula: C29H30FNO4. Mole weight: 475.55. Catalog: APB167934307.
Pitavastatin Impurity 9
Pitavastatin Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 167073-19-0. Molecular formula: C27H28FNO4. Mole weight: 449.52. Catalog: APB167073190.
Pitavastatin lactone
Pitavastatin lactone is a major metabolite of Pitavastatin in humans. Pitavastatin is a potent competitive inhibitor of HMG-CoA reductase little metabolized in hepatic microsomes [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 141750-63-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-125643.
Pitavastatin Lactone-[d4]
One of the isotopic labelled metabolites of Pitavastatin, which has a potent cholesterol-lowering action. Synonyms: Pitavastatin Lactone D4. Grade: >98%. Molecular formula: C25H18D4FNO3. Mole weight: 407.48.
(3R, 5R)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Grade: > 95%. CAS No. 254452-96-5. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01.
(3S,5R)-Pitavastatin Calcium
A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86.
(3S,5R)-tert-Butyl Pitavastatin
A metabolite of Pitavastatin which is a chemically synthesized statin used for hypercholesterolaemia (elevated cholesterol) and for the prevention of cardiovascular disease. Grade: > 95%. Molecular formula: C29H32FNO4. Mole weight: 477.58.
(3S,5S)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which has a potent cholesterol-lowering action. Synonyms: 3-Epi-NK-104; Pitavastatin 3S,5S-Isomer Calcium Salt; (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grade: > 95%. CAS No. 254452-92-1. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.5.
4-Dehydroxy-3-dehydro-pitavastatin-d5 Lactone
A labeled metabolite of Pitavastatin in humans and monkeys. Group: Biochemicals. Alternative Names: (6S) -6- [ (1E) -2- [2-Cyclopropyl-d5-4- (4-fluorophenyl) -3-quinolinyl] ethenyl] tetrahydro-2H-pyran-2-one. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
5-Oxo Pitavastatin
5-Oxo Pitavastatin. Group: Biochemicals. Alternative Names: (3R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic Acid. Grades: Highly Purified. CAS No. 222306-15-2. Pack Sizes: 2.5mg. Molecular Formula: C25H22FNO4, Molecular Weight: 419.44. US Biological Life Sciences.
Worldwide
5-Oxo-Pitavastatin Methyl Ester
5-Oxo-Pitavastatin Methyl Ester is an impurity of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-, methyl ester, (3R,6E)-; Pitavastatin (5R)-Oxo Impurity; (3R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic acid methyl ester; Methyl (3R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoate. Grade: 95%. CAS No. 917752-45-5. Molecular formula: C26H24FNO4. Mole weight: 433.47.
8-Hydroxy Pitavastatin
8-Hydroxy Pitavastatin is one of Pitavastatin metabolites. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-8-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; (3R,5S,6E)-7-hydroxy-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid; Pitavastatin 8'-Hydroxy Impurity. Grade: ≥90%. CAS No. 224320-09-6. Molecular formula: C25H24FNO5. Mole weight: 437.46.
Rosuvastatin Impurity 61 (Pitavastatin Impurity 64). Uses: For analytical and research use. Group: Impurity standards. CAS No. 124752-23-4. Molecular formula: C13H22O5. Mole weight: 258.31. Catalog: APB124752234.
tert-Buthyl Pitavastatin
tert-Buthyl Pitavastatin is the metabolite of Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 586966-54-3. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-135384.
(Z)-Pitavastatin Calcium Salt
An impurity of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Synonyms: (Z)-Pitavastatin Calcium Salt; 1159588-21-2; (Z,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate. Grade: > 95%. CAS No. 1159588-21-2. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01.
2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C32H37NO4. US Biological Life Sciences.
2-((4R,6S)-6-((E)-2-(2-Cyclopropyl-4-phenylquinolin-3-yl)vinyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic Acid tert-Butyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C32H37NO4. Mole weight: 499.64.
2-Amino-2'-fluorobenzophenone
2-Amino-2'-fluorobenzophenone is an intermediate in the preparation of the anticholesteremic Pitavastatin. Group: Biochemicals. Grades: Highly Purified. CAS No. 1581-13-1. Pack Sizes: 100mg, 1g. Molecular Formula: C13H10FNO, Molecular Weight: 215.22. US Biological Life Sciences.
Worldwide
2-Amino-2'-fluorobenzophenone
An intermediate in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: 2-Amino-2'-fluoro-benzophenone; (2-Amino-phenyl)-(2-fluoro-phenyl)-methanone. Grade: ≥ 95%. CAS No. 1581-13-1. Molecular formula: C13H10FNO. Mole weight: 215.22.
2-Amino-4'-fluorobenzophenone
2-Amino-4'-fluorobenzophenone is an intermediate in the preparation of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Uses: An intermediate in the preparation of the anticholesteremic pitavastatin. Synonyms: 2-Aminophenyl 4-Fluorophenyl Ketone; o-(p-Fluorobenzoyl)aniline; (2-Amino-4'-fluoro-phenyl)-phenyl-methanone; 2-Amino-4'-fluorobenzophenone. Grade: ≥95%. CAS No. 3800-6-4. Molecular formula: C13H10FNO. Mole weight: 215.22.
2-Amino-4'-fluorobenzophenone
An intermediate in the preparation of the anticholesteremic Pitavastatin. Group: Biochemicals. Alternative Names: (2-Aminophenyl) (4-fluorophenyl) methanone; 2-Aminophenyl 4-Fluorophenyl Ketone; o-(p-Fluorobenzoyl)aniline. Grades: Highly Purified. CAS No. 3800-6-4. Pack Sizes: 2.5g. US Biological Life Sciences.
[ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium-d5 Bromide is the isotope labelled analog of [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide which is used to prepare artificial HMG-CoA reductase inhibitors. It is also used in the synthesis of pitavastatin calcium. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C37H25D5BrFNP, Molecular Weight: 623.549999999999. US Biological Life Sciences.
[[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-phosphonium Bromide is an impurity in the production of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: Pitavastatin Impurity 44 Bromide; Phosphonium, [[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]methyl]triphenyl-, bromide (1:1). Grade: ≥95%. CAS No. 154057-58-6. Molecular formula: C37H30BrFNP. Mole weight: 618.52.
2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinemethanol is one of Pitavastatin intermediates. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Uses: Pitavastatin intermediate. Synonyms: 2-Cyclopropyl-4-(4'-fluorophenyl)Quinolyl-3-methanol; Pitavastatin Impurity 31. Grade: ≥95%. CAS No. 121660-11-5. Molecular formula: C19H16FNO. Mole weight: 293.33.
2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 868536-53-2. Pack Sizes: 50mg, 500mg. Molecular Formula: C20H17NO2. US Biological Life Sciences.
2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Methyl 2-cyclopropyl-4-phenylquinoline-3-carboxylate; 2-Cyclopropyl-4-phenyl-3-quinolinecarboxylic Acid Methyl Ester; DTXSID00857071; AKOS022175172; SB72967; Methyl2-cyclopropyl-4-phenylquinoline-3-carboxylate. CAS No. 868536-53-2. Molecular formula: C20H17NO2. Mole weight: 303.35.
(2-Cyclopropyl-4-phenylquinolin-3-yl)methanol
(2-Cyclopropyl-4-phenylquinolin-3-yl)methanol is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C19H17NO. US Biological Life Sciences.
Worldwide
(2-Cyclopropyl-4-phenylquinolin-3-yl)methanol
(2-Cyclopropyl-4-phenylquinolin-3-yl)methanol is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (2-CYCLOPROPYL-4-PHENYLQUINOLIN-3-YL)METHANOL; MFCD28384714; SY320331; (2-Cyclopropyl-4-phenyl-3-quinolyl)methanol; F86792. Molecular formula: C19H17NO. Mole weight: 275.34.
2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde
2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde is an impurity of Pitavastatin (P531000), a HMG CoA reductase inhibitor and an antilipemic agent. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C19H15NO. US Biological Life Sciences.
Worldwide
2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde
2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 2-Cyclopropyl-4-phenylquinoline-3-carbaldehyde; 2153433-59-9. Grade: 98%. CAS No. 2153433-59-9. Molecular formula: C19H15NO. Mole weight: 273.33.
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-56-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H15BrFN. US Biological Life Sciences.
Worldwide
3-Cyclopropyl-3-oxopropanoic Acid Methyl Ester
A reagent used in the synthesis of Pitavastatin. Group: Biochemicals. Alternative Names: Methyl 3-Cyclopropyl-3-oxopropionate; Methyl 2- (Cyclopropylcarbonyl) acetate; β-Oxo-cyclopropanepropanoic Acid Methyl Ester. Grades: Highly Purified. CAS No. 32249-35-7. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
3-Cyclopropyl-3-oxopropanoic-d5 Acid Methyl Ester
Reagent used in the synthesis of Pitavastatin. Group: Biochemicals. Alternative Names: Methyl 3-Cyclopropyl-3-oxopropionate-d5; Methyl 2- (Cyclopropylcarbonyl) acetate-d5; β-Oxo-cyclopropanepropanoic-d5 Acid Methyl Ester. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt
(3R,5S)-5-(6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridin-8-yl)-3,5-dihydroxypentanoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: (βR,δS)-6-Cyclopropyl-10-fluoro-7,8-dihydro-β,δ-dihydroxybenzo[k]phenanthridine-8-pentanoic Acid Sodium Salt. Molecular formula: C25H23FNNaO4. Mole weight: 443.44.
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt. Group: Biochemicals. Alternative Names: Defluoro Pitavastatin. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C25H24NNaO4 , Molecular Weight: 425.45. US Biological Life Sciences.
Worldwide
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid Sodium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin. Molecular formula: C25H24NNaO4. Mole weight: 425.45.
(3R,5S,6E)-7-(2-Cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoic Acid tert-Butyl Ester is an intermediate in the synthesis of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (3R,5S,E)-Tert-butyl 7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate; Pitavastatin Impurity compound C; 2-Methyl-2-propanyl (3R,5S,6E)-7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-6-heptenoate; 6-Heptenoic acid, 7-(2-cyclopropyl-4-phenyl-3-quinolinyl)-3,5-dihydroxy-, 1,1-dimethylethyl ester, (3R,5S,6E)-. Grade: 97%. Molecular formula: C29H33NO4. Mole weight: 459.58.
An impurity of Pitavastatin, an HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increases HDL cholesterol in the blood. Synonyms: 6-Heptenoic acid, 7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-, (3S,5R,6E)-; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid; (3S,5R,E)-7-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-3,5-dihydroxyhept-6-enoic acid. Grade: 95%. CAS No. 254452-86-3. Molecular formula: C25H24FNO4. Mole weight: 421.46.
(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt
(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Group: Biochemicals. Alternative Names: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt. Grades: Highly Purified. CAS No. 254452-88-5. Pack Sizes: 2.5mg. Molecular Formula: C25H24FNO4 1/2Ca, Molecular Weight: 440.49. US Biological Life Sciences.
Labeled Pitavastatin intermediate. Group: Biochemicals. Alternative Names: 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylic-d5 Acid Methyl Ester; Methyl 2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinecarboxylate-d5. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt. Group: Biochemicals. Alternative Names: Pitavastatin-3-Oxo Sodium Salt. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H21FNNaO4, Molecular Weight: 441.43. US Biological Life Sciences.
Worldwide
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt
(5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-5-hydroxy-3-oxo-6-heptenoic Acid Sodium Salt is one of pitavastatin derivatives. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: sodium (S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)-5-hydroxy-3-oxohept-6-enoate; sodium (E,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl]-5-hydroxy-3-oxo-hept-6-enoate. Molecular formula: C25H21FNNaO4. Mole weight: 441.43.
6-Cyclopropyl-10-fluoro-7,8-dihydrobenzo[k]phenanthridine is one of Pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: 9-cyclopropyl-15-fluoro-8-azatetracyclo; Pitavastatin Impurity 3 (PP-3). Grade: 98%. CAS No. 1187966-94-4. Molecular formula: C20H16FN. Mole weight: 289.35.
6-Cyclopropyl-10-fluorobenzo[k]phenanthridine
6-Cyclopropyl-10-fluorobenzo[k]phenanthridine is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Pitavastatin Impurity 4 (PP-4). Grade: 98%. CAS No. 1187966-95-5. Molecular formula: C20H14FN. Mole weight: 287.33.
(6S)-6-[(1E)-2-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]-5,6-dihydro-2H-pyran-2-one is an impurity in the production of Pitavastatin, which is a potent HMG-CoA reductase inhibitor for hypercholesterolemia (elevated cholesterol) and prevention of cardiovascular disease. Synonyms: (S)-6-{(E)-2-[2-Cyclopropyl-4-(4-fluoro-phenyl)-quinolin-3-yl]-vinyl}-5,6-dihydro-pyran-2-one; Pitavastatin Impurity 29; (S,E)-6-(2-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)vinyl)-5,6-dihydro-2H-pyran-2-one; 2H-Pyran-2-one, 6-((1E)-2-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)ethenyl)-5,6-dihydro-, (6S)-; 2H-Pyran-2-one, 6-(2-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl)ethenyl)-5,6-dihydro-, (S-(E))-. Grade: ≥95%. CAS No. 148516-15-8. Molecular formula: C25H20FNO2. Mole weight: 385.43.
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