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Pitavastatin Calcium (NK-104 hemicalcium) is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin Calcium (NK-104 hemicalcium) inhibits cholesterol synthesis from acetic acid with an IC 50 of 5.8 nM in HepG2 cells. Pitavastatin Calcium is an efficient hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptor inducer. Pitavastatin Calcium also possesses anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective and reno-protective effects [1] [2] [3] [8]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NK-104 hemicalcium; Pitavastatin hemicalcium. CAS No. 147526-32-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0144.
Pitavastatin calcium salt
1g Pack Size. Group: Bioactive Small Molecules, Organics. Formula: C50H46CaF2N2O8. CAS No. 147526-32-7. Prepack ID 58656411-1g. Molecular Weight 881. See USA prepack pricing.
(3R, 5R)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Grades: > 95%. CAS No. 254452-96-5. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01.
(3S,5R)-Pitavastatin Calcium
A metabolite of Pitavastatin which is a potent inhibitor of HMG-CoA reductase (Ki = 1.7 nM). Synonyms: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt; (3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-88-5. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.86.
(3S,5S)-Pitavastatin Calcium Salt
A metabolite of Pitavastatin which has a potent cholesterol-lowering action. Synonyms: 3-Epi-NK-104; Pitavastatin 3S,5S-Isomer Calcium Salt; (3S,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Grades: > 95%. CAS No. 254452-92-1. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.5.
Pitavastatin 5-Oxo Impurity Calcium Salt
An impurity in the synthesis of Pitavastatin, a HMG-CoA reductase inhibitor that lowers LDL cholesterol and triglycerides and increase HDL cholesterol in your blood. Synonyms: (3R,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3-hydroxy-5-oxo-6-heptenoic acid calcium salt (2:1). CAS No. 2180095-22-9. Molecular formula: C50H42CaF2N2O8. Mole weight: 876.9.
Pitavastatin Defuoro Impurity Calcium Salt
An impurity of Pitavastatin which inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Synonyms: Defluoro Pitavastatin Calcium Salt; CS-0164801; 1258947-30-6; monocalcium mono((3R,5S,E)-7-(2-cyclopropyl-4-phenylquinolin-3-yl)-3,5-dihydroxyhept-6-enoate)? (Pitavastatin Impurity pound(c). Grades: > 95%. CAS No. 1258947-30-6. Molecular formula: C50H48N2O8.Ca. Mole weight: 845.03.
Pitavastatin Impurity 1 Calcium Salt
Pitavastatin Impurity 1 Calcium Salt is one of pitavastatin impurities. Pitavastatin, also called as itavastatin, is a potent HMG-CoA reductase inhibitor. And studies showed that pitavastatin inhibited the activity of Rho-kinase depending on the inactivation of Rho by inhibiting the mevalonate pathway. Molecular formula: C25H23FNO4.1/2Ca. Mole weight: 440.49.
(Z)-Pitavastatin Calcium Salt
An impurity of Pitavastatin which is a relatively newly developed cholesterol lowering agent used to lower high cholesterol and triglycerides in certain patients. Synonyms: (Z)-Pitavastatin Calcium Salt; 1159588-21-2; (Z,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate. Grades: > 95%. CAS No. 1159588-21-2. Molecular formula: C50H46F2N2O8.Ca. Mole weight: 881.01.
[ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium-d5 Bromide is the isotope labelled analog of [ [2-Cyclopropyl-4- (4-fluorophenyl) -3-quinolinyl] methyl] triphenyl-phosphonium Bromide which is used to prepare artificial HMG-CoA reductase inhibitors. It is also used in the synthesis of pitavastatin calcium. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500ug, 5mg. Molecular Formula: C37H25D5BrFNP, Molecular Weight: 623.549999999999. US Biological Life Sciences.
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 154057-56-4. Pack Sizes: 100mg, 500mg. Molecular Formula: C19H15BrFN. US Biological Life Sciences.
Worldwide
(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt
(3S,5R,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic Acid Calcium Salt. Group: Biochemicals. Alternative Names: ent-NK-104; Pitavastatin 3S,5R-Isomer Calcium Salt. Grades: Highly Purified. CAS No. 254452-88-5. Pack Sizes: 2.5mg. Molecular Formula: C25H24FNO4 1/2Ca, Molecular Weight: 440.49. US Biological Life Sciences.
Worldwide
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