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| Product | Description | |
|---|---|---|
| Podophyllotoxin | 1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C22H22O8. CAS No. 518-28-5. Prepack ID 52308554-1g. Molecular Weight 414.41. See USA prepack pricing. |  |
| Podophyllotoxin | 5g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C22H22O8. CAS No. 518-28-5. Prepack ID 52308554-5g. Molecular Weight 414.41. See USA prepack pricing. | |
| Podophyllotoxin | Podophyllotoxin. Group: Biochemicals. Alternative Names: Furo[3', 4':6, 7]naphtha[2, 3-d]-1, 3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl). Grades: Highly Purified. CAS No. 518-28-5,4354-76-1. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C22H22O8. US Biological Life Sciences. |  Worldwide |
| Podophyllotoxin | Podophyllotoxin - Product ID: NST-10-33. Category: Polyphenols. Purity: 98%. Test method: HPLC. CAS No. 518-28-5. Pack Sizes: 5g, 10g, 25g, 50g. Appearance: White to beige colored Powder. Molecular formula: C22H22O8. Mole weight: 414.41. Storage: +2 +8 °C. |  |
| Podophyllotoxin-4-O-glucoside | source from rhizoma podophylli emodi. Uses: Antineoplastic. Synonyms: Podophyllotoxin 7'-O-beta-D-glucopyranoside; (5R,5aR,8aR,9R)-9-(beta-D-Glucopyranosyloxy)-5,8,8a,9-tetrahydro-5-(3,4,5-trimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. Grades: >98%. CAS No. 16481-54-2. Molecular formula: C28H32O13. Mole weight: 576.55. |  |
| Podophyllotoxin 4-O-Glucoside | Podophyllotoxin 4-O-Glucoside. Group: Biochemicals. Alternative Names: (5R,5aR,8aR,9R)-9-( β -D-Glucopyranosyloxy) -5, 8, 8a, 9-tetrahydro-5- (3, 4, 5-trimethoxyphenyl) furo[3', 4': 6, 7]naphtho[2, 3-d]-1, 3-dioxol-6 (5aH) -one; Podophyllotoxin, β-D-glucopyranoside; NSC 163024; Podophyllotoxin 1-O- β-D-Glycoside; Podophyllotoxin 3- β-D-Glucopyranoside; Podophyllotoxin 4-O-Glucoside; Podophyllotoxin 7'-O- β-D-Glucopyranoside; Podophyllotoxin β-D-Glucoside; Podophyllotoxin-4-O- β-D-Glucopyranoside. Grades: Highly Purified. CAS No. 16481-54-2. Pack Sizes: 25mg. Molecular Formula: C28H32O13, Molecular Weight: 576.549999999999. US Biological Life Sciences. | Worldwide |
| Podophyllotoxin-7-O-glucoside (Podophyllotoxin-4-O-glucoside) | Podophyllotoxin-7-O-glucoside (Podophyllotoxin-4-O-glucoside). Group: Biochemicals. Grades: Plant Grade. CAS No. 16481-54-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Podophyllotoxin, 98% | A potent inhibitor of microtubule assembly. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences. | Worldwide |
| Podophyllotoxin Impurity 1 | An impurity of Podophyllotoxin which is a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant. Grades: > 95%. Molecular formula: C21H20O8. Mole weight: 400.39. | |
| Podophyllotoxin Impurity 2 | An impurity of Podophyllotoxin which has been shown to inhibit the growth of various carcinoma cells. Grades: > 95%. Molecular formula: C21H20O7. Mole weight: 384.39. | |
| Podophyllotoxin Impurity 3 | An impurity of Podophyllotoxin which is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Grades: > 95%. Molecular formula: C22H18O8. Mole weight: 410.38. | |
| Podophyllotoxin Impurity 4 | An impurity of Podophyllotoxin which inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. Grades: > 95%. Molecular formula: C22H20O8. Mole weight: 412.4. | |
| Podophyllotoxin Impurity 5 | An impurity of Podophyllotoxin which is a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant. Grades: > 95%. Molecular formula: C22H22O7. Mole weight: 398.42. | |
| Podophyllotoxin Impurity 6 | An impurity of Podophyllotoxin which has been shown to inhibit the growth of various carcinoma cells. Grades: > 95%. Molecular formula: C22H22O8. Mole weight: 414.42. | |
| Podophyllotoxin Impurity 7 | An impurity of Podophyllotoxin which is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Grades: > 95%. Molecular formula: C28H34O13. Mole weight: 578.58. | |
| Podophyllotoxin Impurity 8 | An impurity of Podophyllotoxin which inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. Grades: > 95%. Molecular formula: C28H32O13. Mole weight: 576.56. | |
| Podophyllotoxin (Podofilox, NSC 24818, Podophyllinic acid lactone) | Potent microtubule assembly inhibitor. Anticancer compound. Cell death inducer. DNA topoisomerase II inhibitor. Cell cycle inhibitor at the metaphase. Antiviral and antihelminthic. Group: Biochemicals. Alternative Names: Podofilox, NSC 24818, Podophyllinic acid lactone. Grades: Highly Purified. CAS No. 518-28-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 4'-De methyl desoxypodophyllotoxin | 4'-De methyl desoxypodophyllotoxin. Group: Biochemicals. Alternative Names: [5R-(5α,5a β, 8aα)]-5, 8, 8a, 9-Tetrahydro-5-(4-hydroxy-3, 5-dimethoxyphenyl)-furo[3', 4':6, 7]naphtho[2, 3-d]-1, 3-dioxol-6(5aH)-one; Podophyllotoxin, 4'-O-demethyl-4-deoxy-(7CI,8CI); 4-De methyl deoxypodophyllotoxin; 4'-De methyl deoxypodophyllotoxin; A 80198; DDPT. Grades: Highly Purified. CAS No. 3590-93-0. Pack Sizes: 50mg. Molecular Formula: C22H22O7, Molecular Weight: 398.41. US Biological Life Sciences. | Worldwide |
| 4'-Demethylepipodophyllotoxin | 4'-Demethylepipodophyllotoxin (4'-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule assembly.IC50 Value: 0.31uM(EC5 0in HL60 cell, MTT assay, 48h); 0.37uM(EC50 in HepG2 cell, MTT assay, 48h) Target: microtubulein vitro: 4-TMP-DMEP showed strong cytotoxicity activity against the above-mentioned five tumor cell lines. The EC50s of 4-TMP-DMEP against these tumor cell lines ranged from 0.24 to 0.11 μM, which were 0.29 to 3618 times lower than that of DMEP.in vivo: Treatment of animals with DMEP (until the end of the experiment), 30 min before TPA treatment, significantly reduced the tumor incidence, tumor volume and the conversion efficiency of papillomas to squamous cell carcinomas. The tumor formation and growth was also delayed by DMEP pre-treatment. Group: Inhibitors. Alternative Names: 4-Domethylpodophyllotoxin, 4'-demethyl-epi-podophyllotoxin. CAS No. 6559-91-7. Molecular formula: C21H20O8. Mole weight: 400.38. Appearance: Powder. Purity: 0.98. IUPACName: (5S,5aR,8aR,9R)-5-hydroxy-9-(4-hydroxy-3,5-dimethoxyphenyl)-5a,6,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-8-one. Canonical SMILES: COC1=CC (=CC (=C1O)OC)[C@H]2[C@@H]3[C@H] (COC3=O)[C@@H] (C4=CC5=C (C=C24)OCO5)O. Density: 1.446±0.06 g/ml. Catalog: ACM6559917. |  |
| 4'-De methyl podophyllotoxin | 4'-De methyl podophyllotoxin. Group: Biochemicals. Grades: Highly Purified. CAS No. 40505-27-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. US Biological Life Sciences. | Worldwide |
| 4'-(O-Podophyllotoxin-9-oxy) Etoposide | 4'-(O-Podophyllotoxin-9-oxy) Etoposide is an impurity of Etoposide. Etoposide is a DNA topoisomerase II inhibitor, as well as semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an antineoplastic. Molecular formula: C50H50O20. Mole weight: 970.92. | |
| De methyl podophyllotoxin, 4'- | De methyl podophyllotoxin, 4'-. Group: Biochemicals. CAS No. 6559-91-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Deoxypodophyllotoxin | Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule , has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis [1]. Deoxypodophyllotoxin induces cell autophagy and apoptosis [2]. Deoxypodophyllotoxin evokes increase of intracellular Ca 2+ concentrations in DRG neurons [3]. Uses: Scientific research. Group: Natural products. CAS No. 19186-35-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2500. |  |
| Deoxypodophyllotoxin | Deoxypodophyllotoxin (DPT), a derivative of podophyllotoxin, is a lignan with potent antimitotic, anti-inflammatory and antiviral properties isolated from Anthriscus sylvestris. Deoxypodophyllotoxin, targets the microtubule, has a major impact in oncology not only as anti-mitotics but also as potent inhibitors of angiogenesis. Deoxypodophyllotoxin induces cell autophagy and apoptosis. Deoxypodophyllotoxin evokes increase of intracellular Ca2+ concentrations in DRG neurons. Group: Inhibitors. CAS No. 19186-35-7. Molecular formula: C22H22O7. Mole weight: 398.4. Appearance: Powder. Purity: 0.98. IUPACName: (5R,5aR,8aR)-5-(3,4,5-trimethoxyphenyl)-5a,8,8a,9-tetrahydro-5H-[2]benzofuro[5,6-f][1,3]benzodioxol-6-one. Canonical SMILES: COC1=CC (=CC (=C1OC)OC)C2C3C (CC4=CC5=C (C=C24)OCO5)COC3=O. Catalog: ACM19186357. | |
| (-)-deoxypodophyllotoxin synthase | The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. It catalyses the closure of the central six-membered ring in the aryltetralin scaffold. Group: Enzymes. Synonyms: 2-ODD (gene name). Enzyme Commission Number: EC 1.14.11.50. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0669; (-)-deoxypodophyllotoxin synthase; EC 1.14.11.50; 2-ODD (gene name). Cat No: EXWM-0669. |  |
| 2'',3''-Bis-O-(Dichloroacetyl) Etoposide | 2'',3''-Bis-O-(Dichloroacetyl) Etoposide is an impurity of Etoposide (E933750). Etoposide is a DNA topoisomerase II inhibitor. Etoposide is semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an Antineoplastic. Group: Biochemicals. Grades: Highly Purified. CAS No. 260974-95-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C33H32Cl4O15, Molecular Weight: 810.41. US Biological Life Sciences. | Worldwide |
| 2'',3''-Bis-O-(Dichloroacetyl) Etoposide | 2'',3''-Bis-O-(Dichloroacetyl) Etoposide is an impurity of Etoposide. Etoposide is a DNA topoisomerase II inhibitor. Etoposide is a semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide and it is an antineoplastic. Synonyms: 9-[[2,3-Bis-O-(2,2-dichloroacetyl)-4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one 6-Acetate; (5R,5aR,8aR,9S)-9-[[2,3-Bis-O-(dichloroacetyl)-4,6-O-(1R)-ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one. CAS No. 260974-95-6. Molecular formula: C33H32Cl4O15. Mole weight: 810.41. | |
| 2-Methyl-1H-indol-6-amine | 2-Methyl-1H-indol-6-amine is used in the synthesis of aza-podophyllotoxin derivatives, with some compounds exhibiting stronger growth inhibition activity in cancer cell lines (Zr-75-1, MCF7, KB, Gurav, DWD, Colo-205, A-549 and Hop62). Group: Biochemicals. Grades: Highly Purified. CAS No. 102308-53-2. Pack Sizes: 50mg, 100mg. Molecular Formula: C9H10N2, Molecular Weight: 146.19. US Biological Life Sciences. | Worldwide |
| bursehernin 5'-monooxygenase | This cytochrome P450 enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. Group: Enzymes. Synonyms: CYP71CU1 (gene name); bursehernin 5'-hydroxylase. Enzyme Commission Number: EC 1.14.13.213. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0815; bursehernin 5'-monooxygenase; EC 1.14.13.213; CYP71CU1 (gene name); bursehernin 5'-hydroxylase. Cat No: EXWM-0815. | |
| Etoposide | An antitumor agent. A topoisomerase II inhibitor. A derivative of podophyllotoxin that has major activity against a number of tumors, including germ cell neoplasms, small cell lung cancer, and malignant lymphoma. Induces apoptosis in human T cells, mouse thymocytes, and HL-60 human leukemia cells. Group: Biochemicals. Alternative Names: 4?-De methyl epipodophyllotoxin; 9-(4,6-O-ethylidene- β-D-glucopyranoside); (5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene- β -D-glucopyranosyl]oxy]-5, 8, 8a, 9-tetrahydro-5- (4-hydroxy-3, 5-dimethoxyphenyl) furo[3, 4: 6, 7]naphtho[2, 3-d]-1, 3-dioxol-6 (5aH) -one; EPEG; VP 16-213; VePesid; Vepesid J; Zuyeyidal; trans-Etoposide. Grades: Highly Purified. CAS No. 33419-42-0. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??O??, Molecular Weight: 588.56. US Biological Life Sciences. | Worldwide |
| Etoposide-d3 | A labeled DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic. Group: Biochemicals. Alternative Names: (5R,5aR,8aR,9S)-. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Native Rhodotorula glutinis Phenylalanine Ammonia-Lyase | Phenylalanine Ammonia-Lyase from Rhodotorula glutinis can be cleaved and inactivated by the proteases chymotrypsin, subtilisin, and trypsin. Applications: Phenylalanine ammonia-lyase has been used in a study to assess the effect of heat treatment on lignification of postharvest bamboo shoots. it has also been used in a study to investigate the effect of light on gene expression and podophyllotoxin biosynthesis in linum album cell culture. Group: Enzymes. Synonyms: phenylalanine ammonia-lyase; EC 4.3.1.24; phenylalanine deaminase; phenylalanine ammonium-lyase; PAL; L-phenylalanine ammonia-lyase; Phe ammonia-lyase; 9024-28-6. Enzyme Commission Number: EC 4.3.1.24. CAS No. 9024-28-6. PAL. Activity: 0.8-2.0 units/mg protein. Storage: -20°C. Form: buffered aqueous glycerol solution; Solution in 60% glycerol, 3 mM Tris-HCl, pH 7.5, containing up to 0.5 M (NH4)2SO4. Source: Rhodotorula glutinis. phenylalanine ammonia-lyase; EC 4.3.1.24; phenylalanine deaminase; phenylalanine ammonium-lyase; PAL; L-phenylalanine ammonia-lyase; Phe ammonia-lyase; 9024-28-6. Cat No: NATE-0502. | |
| Natural Product Derivatives Library | The library consists of more than 4, 000 members belonging 22 scaffolds (average 180 compounds per scaffold). - The library includes the following sub-libraries:- Cytisine-based sub-library- Matrine-based sub-library- Podophyllotoxin-based sub-library- Sub-library based on naturally occurring privileged BBS such ashydroxy-prolines, triptamine, nor-tropolone etc. - TargetMol "Beyond RO5" filters have been applied for the library population (See Phys-chem parameters for the library members). - NO Med-Chem restrictions (widely accepted and proprietary TargetMol substructure filters on reactive functionalities, toxicophoric, instability suspicions etc. ). - More than 90% purity for each library member confirmed by LC-MS or NMR analysis. Uses: Scientific use. Product Category: NY1000. Categories: Natural Product Derivatives Libraries. |  |
| (-)-pluviatolide 4-O-methyltransferase | The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. Group: Enzymes. Synonyms: OMT3 (gene name). Enzyme Commission Number: EC 2.1.1.323. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1931; (-)-pluviatolide 4-O-methyltransferase; EC 2.1.1.323; OMT3 (gene name). Cat No: EXWM-1931. | |
| (-)-pluviatolide synthase | The enzyme, characterized from the plants Sinopodophyllum hexandrum and Podophyllum peltatum, catalyses the formation of a methylenedioxy-bridge. It is involved in the biosynthesis of podophyllotoxin, a non-alkaloid toxin lignan whose derivatives are important anticancer drugs. Group: Enzymes. Synonyms: CYP719A23 (gene name). Enzyme Commission Number: EC 1.14.21.11. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1022; (-)-pluviatolide synthase; EC 1.14.21.11; CYP719A23 (gene name). Cat No: EXWM-1022. | |
| Podofilox | Podofilox (Podophyllotoxin) is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Uses: Scientific research. Group: Natural products. Alternative Names: Podophyllotoxin. CAS No. 518-28-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-15552. | |
| Teniposide | Teniposide is a chemotherapeutic medication mainly used in the treatment of childhood acute lymphocytic leukemia (ALL).It is in a class of drugs known as podophyllotoxin derivatives and slows the growth of cancer cells in the body. Uses: Antineoplastic agents; enzyme inhibitors; nucleic acid synthesis inhibitors. Synonyms: NSC-122819; NSC 122819; NSC122819; VM26; VM-26; VM 26; HSDB 6546; HSDB6546; HSDB-6546; CCRIS 2058. Brand name: Vumon; Vehem. Abbreviations: EPT; PTG. Grades: >98%. CAS No. 29767-20-2. Molecular formula: C32H32O13S. Mole weight: 656.65. | |
| Teniposide | Teniposide is a podophyllotoxin derivative, acts as a topoisomerase II inhibitor, and used as a chemotherapeutic agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: VM26. CAS No. 29767-20-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13761. | |
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