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Anti-fungal agent; sterol α-demethylase inhibitor. Posaconazole is a highly potent broadspectrum antifungal drug. It blocks the synthesis of ergosterol by inhibiting of the enzyme lanosterol 14α-demethylase resulting in accumulation of methylated sterol precursors. In contrast to other antifungal azoles, posaconazole has been reported not to induce the efflux pump mechanism. Posaconazole was able to produce a parasitological cure in a mouse model of the chronic stage of Chagas disease. Group: Biochemicals. Alternative Names: 2, 5-Anhydro-1, 3, 4-trideoxy-2-C- (2, 4-difluorophenyl) -4- [ [4- [4- [4- [1- [ (1S, 2S) -1-ethyl-2-hydroxypropyl] -1, 5-dihydro-5-oxo-4H-1, 2, 4-triazol-4-yl] phenyl] -1-piperazinyl] phenoxy] methyl] -1- (1H-1, 2, 4-triazol-1-yl) -D-threo-pentitol; Noxafil; Sch 56592. Grades: Highly Purified. CAS No. 171228-49-2. Pack Sizes: 250mg, 500mg, 1g, 5g. Molecular Formula: C??H??F?N?O?, Molecular Weight: 700.78. US Biological Life Sciences.
Worldwide
Posaconazole
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Posaconazole;171228-49-2;Noxafil;Sch 56592;SCH56592;SCH-56592;Posaconazole SP;Schering 56592;UNII-6TK1G07BHZ;4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one;4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-TRIAZOL-1-YL)METHYL)-5-(2,4-DIFLUOROPHENYL)TETRAHYDROFURAN-3-YL)METHOXY)PHENYL)PIP. Product Category: Inhibitors. Appearance: Solid. CAS No. 171228-49-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.8g/mol. Purity: 0.9994. IUPACName: 4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)-5-(1,2,4-triazol-1-ylmethyl)oxolan-3-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-2-[(2S,3S)-2-hydroxypentan-3-yl]-1,2,4-triazol-3-one. Canonical SMILES: CCC(C(C)O)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5CC(OC5)(CN6C=NC=N6)C7=C(C=C(C=C7)F)F. Product ID: ACM171228492. Alfa Chemistry ISO 9001:2015 Certified.
Posaconazole
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SCH 56592. CAS No. 171228-49-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17373.
Posaconazole
Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: For research used only. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol; Noxafil; Sch 56592. Grades: >98%. CAS No. 171228-49-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
A diastereoisomer of Posaconazole which is an inhibitor of 14-alpha-demethylase and prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.8.
Posaconazole Diastereoisomer 1 (R,R,R,R)
Posaconazole Diastereoisomer 1 (R,R,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Impurity 31; all-(R)-Posaconazole; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one; (3R,5R,2R,3R)-posaconazole. Grades: 95%. CAS No. 170985-61-2. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 2 (R,S,R,R)
Posaconazole Diastereoisomer 2 (R,S,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: all-(R)-Posaconazole; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)Methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)Methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2R,3R)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one. Grades: > 95%. CAS No. 213381-05-6. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 3
Posaconazole Diastereoisomer 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1229428-89-0. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. Catalog: APB1229428890.
Posaconazole Diastereoisomer 3 (S,R,R,R)
Posaconazole Diastereoisomer 3 (S,R,R,R) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 1229428-89-0. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 4 (S,S,R,S)
Posaconazole Diastereoisomer 4 (S,S,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 5
Posaconazole Diastereoisomer 5. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1229428-90-3. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. Catalog: APB1229428903.
Posaconazole Diastereoisomer 5 (S,R,R,S)
Posaconazole Diastereoisomer 5 (S,R,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3R,5S)Posaconazole; 1229428-90-3. Grades: > 95%. CAS No. 1229428-90-3. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 6 (R,R,R,S)
Posaconazole Diastereoisomer 6 (R,R,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: D-threo-Pentitol, 2,?5-anhydro-1,?3,?4-trideoxy-2-C-(2,?4-difluorophenyl)?-4-[[4-[4-[4-[1-[(1R,?2S)?-1-ethyl-2-hydroxypropyl]?-1,?5-dihydro-5-oxo-4H-1,?2,?4-triazol-4-yl]?phenyl]?-1-piperazinyl]?phenoxy]?methyl]?-1-(1H-1,?2,?4-triazol-1-yl)?-; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[4-[4-[1-[(1R,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-piperazinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol. Grades: > 95%. CAS No. 171228-50-5. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 7 (R,S,R,S)
Posaconazole Diastereoisomer 7 (R,S,R,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3R,5S,2R,3S)-Posaconazole. Grades: > 95%. CAS No. 213381-04-5. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer 9 (S,S,S,S)
Posaconazole Diastereoisomer 9 (S,S,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: all-(S)-Posaconazole; 4-(4-(4-(4-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. CAS No. 1246391-73-0. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer Intermediate 2
Posaconazole Diastereoisomer Intermediate 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 166583-12-6. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47. Catalog: APB166583126.
Posaconazole Diastereoisomer Related Compound 1
Posaconazole Diastereoisomer Related Compound 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (5R-trans)-Toluene-4-sulfonic Acid 5-(2,4-Difluorophenyl)-5-[1,2,4]triazol-1-ylmethyltetrahydrofuran-3-ylmethyl Ester; 1,4-Anhydro-2,3,5-trideoxy-4-C-(2,4-difluorophenyl)-2-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-5-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol. Grades: > 95%. CAS No. 159811-30-0. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47.
Posaconazole Diastereoisomer Related Compound 2
Posaconazole Diastereoisomer Related Compound 2 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol; D-erythro-Pentitol, 2, ?5-anhydro-1, ?3, ?4-trideoxy-2-C- (2, ?4-difluorophenyl) ?-4-[[[ (4-methylphenyl) ?sulfonyl]?oxy]?methyl]?-1- (1H-1, ?2, ?4-triazol-1-yl) ?-. Grades: > 95%. CAS No. 166583-12-6. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47.
Posaconazole Diastereoisomer Related Compound 3
Posaconazole Diastereoisomer Related Compound 3 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2-((2R,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 2185472-85-7. Molecular formula: C30H35N5O3. Mole weight: 513.63.
Posaconazole Diastereoisomer Related Compound 4
Posaconazole Diastereoisomer Related Compound 4 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2-((2S,3R)-2-(benzyloxy)pentan-3-yl)-4-(4-(4-(4-hydroxyphenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. CAS No. 2125944-53-6. Molecular formula: C30H35N5O3. Mole weight: 513.63.
Posaconazole Diastereoisomer Related Compound 5
Posaconazole Diastereoisomer Related Compound 5 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[(4-methylphenyl)sulfonyl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-L-threo-pentitol. Grades: > 95%. CAS No. 149809-42-7. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47.
Posaconazole Diastereoisomer Related Compound 6
A diastereoisomer of Posaconazole which is a broad-spectrum antifungal. Grades: > 95%. Molecular formula: C30H35N5O3. Mole weight: 513.65.
Posaconazole Diastereoisomer Related Compound 8
Cas No. 149809-43-8.
Posaconazole Diastereoisomer (R,R,S,S)
Posaconazole Diastereoisomer (R,R,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((4H-1,2,4-Triazol-4-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one; (1,2,4-Triazol-4-yl) Posaconazole. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Diastereoisomer (S,R,S,S)
Posaconazole Diastereoisomer (S,R,S,S) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: (3S,5R,2S,3S)-Posaconazole. Grades: 95%. CAS No. 213381-02-3. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Enantiomer
Posaconazole Enantiomer is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ent-Posaconazole. Grades: > 95%. CAS No. 2243785-97-7. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole hydrate
Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity. Posaconazole strongly inhibits 14-alpha demethylase, a cytochrome P450-dependent enzyme. Posaconazole is a sterol C14? demethylase inhibitor with an IC50 of 0.25 nM. Inhibition of 14-alpha-demethylase prevents the conversion of lanosterol to ergosterol, an important component of the fungal cell wall. Inhibition of ergosterol synthesis changes the fungal cell membrane composition and integrity, alters membrane permeability and eventually leads to fungal cell lysis. Compared to other azole antifungals, posaconazole is a significantly more potent inhibitor of sterol 14-alpha demethylase. Posaconazole is the most advanced candidate for the treatment of Chagas disease. Posaconazole has entered in a phase II clinical trial in the treatment of mycoses. Synonyms: SCH56592 hydrate; SCH-56592 hydrate; SCH 56592 hydrate. Grades: >98%. CAS No. 1198769-38-8. Molecular formula: C37H44F2N8O5. Mole weight: 718.79.
Posaconazole Impurity 1
Posaconazole Impurity 1 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Imidazolidine Impurity; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[4-[3-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-1-imidazolidinyl]phenoxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol. Grades: > 95%. CAS No. 1388148-29-5. Molecular formula: C36H40F2N8O4. Mole weight: 686.75.
Posaconazole Impurity 10 (POS-A)
Posaconazole Impurity 10 (POS-A) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((R)-2-oxopentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C37H40F2N8O4. Mole weight: 698.76.
Posaconazole Impurity 11 (POS-B)
Posaconazole Impurity 11 (POS-B) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)-3-(4-(4-(4-(1-((2S,3R)-2-hydroxypentan-3-yl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phenyl)piperazin-1-yl)phenoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C60H69F2N13O7. Mole weight: 1122.27.
Posaconazole Impurity 12 (POS-G)
Posaconazole Impurity 12 (POS-G) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C37H40F2N8O5. Mole weight: 714.76.
Posaconazole Impurity 13 (POS-H)
Posaconazole Impurity 13 (POS-H) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C37H40F2N8O6. Mole weight: 730.76.
Posaconazole Impurity 14 (POS-I)
Posaconazole Impurity 14 (POS-I) is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C36H40F2N8O5. Mole weight: 702.75.
Posaconazole Impurity 15
Posaconazole Impurity 15 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C20H18ClF2N3O4S. Mole weight: 469.89.
Posaconazole Impurity 15
Posaconazole Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1246391-73-0. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. Catalog: APB1246391730.
Posaconazole Impurity 16
Posaconazole Impurity 16 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate; D-erythro-Pentitol, 1,4-anhydro-2-[[[(4-chlorophenyl)sulfonyl]oxy]methyl]-2,3,5-trideoxy-4-C-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)-; 1,4-Anhydro-2-({[(4-chlorophenyl)sulfonyl]oxy}methyl)-2,3,5-trideoxy-4-(2,4-difluorophenyl)-5-(1H-1,2,4-triazol-1-yl)-D-erythro-pentitol; Posaconazole Intermediate (R-trans isomer). Grades: ≥95%. CAS No. 2243786-07-2. Molecular formula: C20H18ClF2N3O4S. Mole weight: 469.89.
Posaconazole Impurity 17
Posaconazole Impurity 17 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol. Grades: > 95%. CAS No. 149882-18-8. Molecular formula: C14H15F2N3O2. Mole weight: 295.28.
Posaconazole Impurity 18
Posaconazole Impurity 18 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol. Grades: > 95%. Molecular formula: C14H15F2N3O2. Mole weight: 295.28.
Posaconazole Impurity 19
Posaconazole Impurity 19 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate. Grades: > 95%. Molecular formula: C20H18ClF2N3O4S. Mole weight: 469.89.
Posaconazole Impurity 2
Posaconazole Impurity 2 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(8-(((3S,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-phenyltetrahydrofuran-3-yl)methoxy)-1,2,3,5-tetrahydro-4H-benzo[e][1,4]diazepin-4-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C36H42N8O4. Mole weight: 650.77.
Posaconazole Impurity 20
Posaconazole Impurity 20 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methanol. Grades: > 95%. Molecular formula: C14H15F2N3O2. Mole weight: 295.28.
Posaconazole Impurity 20
Posaconazole Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1229428-91-4. Molecular formula: C37H42F2N8O4. Mole weight: 700.79. Catalog: APB1229428914.
Posaconazole Impurity 21
Posaconazole Impurity 21 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: ((3S,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-chlorobenzenesulfonate. Grades: > 95%. CAS No. 175712-02-4. Molecular formula: C20H18ClF2N3O4S. Mole weight: 469.89.
Posaconazole Impurity 22
Posaconazole Impurity 22 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Benzodiazepine Impurity; 2,5-Anhydro-1,3,4-trideoxy-2-C-(2,4-difluorophenyl)-4-[[[4-[4-[1-[(1S,2S)-1-ethyl-2-hydroxypropyl]-1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl]phenyl]-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-7-yl]oxy]methyl]-1-(1H-1,2,4-triazol-1-yl)-D-threo-pentitol. Grades: > 95%. CAS No. 1388148-30-8. Molecular formula: C36H40F2N8O4. Mole weight: 686.75.
Posaconazole Impurity 23
Posaconazole Impurity 23 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. CAS No. 687132-01-0. Molecular formula: C23H29N5O3. Mole weight: 423.51.
Posaconazole Impurity 23 Dihydrochloride
Posaconazole Impurity 23 Dihydrochloride is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Molecular formula: C23H29N5O3.2HCl. Mole weight: 496.43.
Posaconazole Impurity 24
Posaconazole Impurity 24 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C21H21F2N3O4S. Mole weight: 449.47.
Posaconazole Impurity 25
Posaconazole Impurity 25 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2S,3R)-2-(benzyloxy)pentan-3-yl)formohydrazide. Grades: > 95%. CAS No. 1428118-40-4. Molecular formula: C13H20N2O2. Mole weight: 236.31.
Posaconazole Impurity 25
Posaconazole Impurity 25. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1042398-26-4. Molecular formula: C16H19F2IO3. Mole weight: 424.23. Catalog: APB1042398264.
Posaconazole Impurity 25 Oxalate
Posaconazole Impurity 25 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Molecular formula: C13H20N2O2.C2H2O4. Mole weight: 326.34.
Posaconazole Impurity 26
Posaconazole Impurity 26 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5S)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Impurity 27
Posaconazole Impurity 27 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,6-difluorophenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3R)-2-hydroxypentan-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.78.
Posaconazole Impurity 28
Posaconazole Impurity 28 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: TAZ POSA; 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2-fluoro-4-(1H-1,2,4-triazol-1-yl)phenyl)tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-1-((2S,3S)-2-hydroxypentan-3-yl)-1H-1,2,4-triazol-5(4H)-one. Grades: > 95%. Molecular formula: C39H44FN11O4. Mole weight: 749.83.
Posaconazole Impurity 29
An impurity of Posaconazole which is the most advanced candidate for the treatment of Chagas disease compared to other azole antifungals. Grades: > 95%. Molecular formula: C21H21F2N3O4S. Mole weight: 449.48.
Posaconazole Impurity 3
Posaconazole Impurity 3 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Grades: > 95%. Molecular formula: C30H35N5O3. Mole weight: 513.63.
Posaconazole Impurity 30
An impurity of Posaconazole which has entered in a phase II clinical trial in the treatment of mycoses. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.8.
Posaconazole Impurity 31
An impurity of Posaconazole which is a broad-spectrum, second generation, triazole compound with a significantly more potent inhibitor of sterol 14-alpha demethylase compared to other azole antifungals. Grades: > 95%. Molecular formula: C37H42F2N8O4. Mole weight: 700.8.
Posaconazole Impurity 32
Posaconazole Impurity 32 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Hydroxy Carbamate Impurity; [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenyl Ester. CAS No. 184177-81-9. Molecular formula: C23H23N3O3. Mole weight: 389.45.
Posaconazole Impurity 32 Oxalate
Posaconazole Impurity 32 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Hydroxy Carbamate Impurity Oxalate; [4-[4-(4-Hydroxyphenyl)-1-piperazinyl]phenyl]carbamic Acid Phenyl Ester Oxalate. Molecular formula: C23H23N3O3.C2H2O4. Mole weight: 479.48.
Posaconazole Impurity 33
Posaconazole Impurity 33 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Uses: Posaconazole intermediate. antifungal agent. Synonyms: [S- (R*, R*) ]-2-[1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde; 2-[ (1S, 2S) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde. Grades: 95%. CAS No. 170985-85-0. Molecular formula: C13H20N2O2. Mole weight: 236.31.
Posaconazole Impurity 33 Oxalate
Posaconazole Impurity 33 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2S,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide oxalate; 2-[ (1S, 2S) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde Oxalate. Grades: >95%. CAS No. 1887197-42-3. Molecular formula: C13H20N2O2.C2H2O4. Mole weight: 326.34.
Posaconazole Impurity 34
Posaconazole Impurity 34 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2R,3R)-2-(Benzyloxy)pentan-3-yl)formohydrazide; 2-[ (1R, 2R) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde. CAS No. 2125943-81-7. Molecular formula: C13H20N2O2. Mole weight: 236.31.
Posaconazole Impurity 34 Oxalate
Posaconazole Impurity 34 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2R,3R)-2-(Benzyloxy)pentan-3-yl)formohydrazide Oxalate; 2-[ (1R, 2R) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde Oxalate. Molecular formula: C13H20N2O2.C2H2O4. Mole weight: 326.34.
Posaconazole Impurity 35
Posaconazole Impurity 35 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2R,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide; 2-[ (1S, 2R) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde. CAS No. 2243785-81-9. Molecular formula: C13H20N2O2. Mole weight: 236.31.
Posaconazole Impurity 35 Oxalate
Posaconazole Impurity 35 Oxalate is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: N'-((2R,3S)-2-(Benzyloxy)pentan-3-yl)formohydrazide Oxalate; 2-[ (1S, 2R) -1-Ethyl-2- (phenylmethoxy) propyl]hydrazinecarboxaldehyde Oxalate. Molecular formula: C13H20N2O2.C2H2O4. Mole weight: 326.34.
Posaconazole Impurity 39
Posaconazole Impurity 39 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,?5-Anhydro-1,?3,?4-trideoxy-2-C-(2,?4-difluorophenyl)?-4-[[4-[4-[4-[1-[(1S,?2S)?-1-ethyl-2-hydroxypropyl]?-1,?5-dihydro-5-oxo-4H-1,?2,?4-triazol-4-yl]?phenyl]?-3-oxo-1-piperazinyl]?phenoxy]?methyl]?-1-(1H-1,?2,?4-triazol-1-yl)?-D-threo-pentitol; 3-Oxo-posaconazole (3-oxo-1-piperazinyl). CAS No. 357189-94-7. Molecular formula: C37H40F2N8O5. Mole weight: 714.76.
Posaconazole Impurity 4
Posaconazole Impurity 4 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: D-Threo-Pentitol; 2,?5-Anhydro-1,?3,?4-trideoxy-2-C-(2,?4-difluorophenyl)?-4-(hydroxymethyl)?-1-(1H-1,?2,?4-triazol-1-yl)?-D-threo-pentitol. Grades: >95%. CAS No. 160709-02-4. Molecular formula: C14H15F2N3O2. Mole weight: 295.28.
Posaconazole Impurity 40
Posaconazole Impurity 40 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: 2,4-Dihydro-2-[(1S,2S)-1-ethyl-2-hydroxypropyl]-4[4-(1-piperazinyl)phenyl]-3H-1,2,4-triazol-3-one. Grades: >95%. Molecular formula: C17H25N5O2. Mole weight: 331.41.
Posaconazole Impurity 42
Posaconazole Impurity 42 is an impurity of Posaconazole. Posaconazole is a broad-spectrum triazole compound that is active against fungi by inhibiting the lanosterol 14α-demethylase enzyme. Synonyms: Posaconazole Mono N-Oxide (Regioisomers Mixtures). CAS No. 1902954-05-5. Molecular formula: C37H42F2N8O5. Mole weight: 716.78.
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