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| Product | Description | |
|---|---|---|
| Pranlukast | 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C27H23N5O4. CAS No. 103177-37-3. Prepack ID 88619956-25mg. Molecular Weight 481.5. See USA prepack pricing. |  |
| Pranlukast | Cysteinyl leukotriene receptor antagonist. The cysteinyl leukotrienes (CysLTs) LTC4 and LTD4 are potent mediators of asthma and hypersensitivity. They induce bronchoconstriction, increase microvascular permeability, and are vasoconstrictors of coronary arteries. Their biological effects are transduced by a pair of G protein-coupled receptors, CysLT1 and CysLT2.1,2,3 Pranlukast (ONO-1078) is a potent, selective and orally active cysteinyl leukotriene1 (CysLT1) receptor antagonist.4 Sold under the trade name Ultair, it was the first cysteinyl (peptidyl) leukotriene receptor antagonist (LTRA) marketed for the treatment of asthma.5 Clinical studies in Japan, Europe, and North America all show that pranlukast significantly attenuates bronchoconstriction in response to a variety of allergen challenges as well as to inhaled LTD4.5 Pranlukast binds to the human CysLT1 and CysLT2 receptors with IC50 values of approximately 4-7nM and 3,600nM, respectively. Group: Biochemicals. Alternative Names: N-{4-Oxo-2- (1H-tetrazol-5-yl) -4H-1-benzopyran-8-yl]-4- (4-phenylbutoxy) benzamide; ONO-1078; ONO-RS-411; Onon; Ultair. Grades: Highly Purified. CAS No. 103177-37-3. Pack Sizes: 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??N?O?, Molecular Weight: 481.5. US Biological Life Sciences. |  Worldwide |
| Pranlukast | Pranlukast is a highly potent, selective and competitive antagonist of peptide leukotriene s. Pranlukast inhibits [ 3 H]LTE 4 , [ 3 H]LTD 4 , and [ 3 H]LTC 4 bindings to lung membranes with K i s of 0.63±0.11, 0.99±0.19, and 5640±680 nM, respectively. Uses: Scientific research. Group: Natural products. Alternative Names: ONO-1078. CAS No. 103177-37-3. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0290. |  |
| Pranlukast | Pranlukast is a selective cysteinyl leukotriene receptor antagonist. Pranlukast has an anti-inflammatory effect on bronchial eosinophilic infiltration. Pranlukast is now widely used in the treatment of asthma. Uses: Leukotriene antagonists. Synonyms: Pranlukast; Ono-1078; ONO 1078; ONO-1078; ONO-RS 411; ONO-RS-411; SB 205312. Grades: >98%. CAS No. 103177-37-3. Molecular formula: C27H23N5O4. Mole weight: 481.5. |  |
| Pranlukast hemihydrate | ?98% (HPLC), white solid. Group: Fluorescence/luminescence spectroscopy. |  |
| Pranlukast Impurity 1 | Pranlukast Impurity 1 is an impurity of Pranlukast. Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It can be used as an antiasthmatic. Synonyms: 4-Oxo-8-[4-(4-phenylbutoxy)benzoylamino]-4H-1-benzopyran-2-carboxylic Acid. Grades: > 95%. CAS No. 211116-98-2. Molecular formula: C27H23NO6. Mole weight: 457.48. | |
| Pranlukast Impurity 2 | Pranlukast Impurity 2 is an impurity of Pranlukast. Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. It can be used as an antiasthmatic. Synonyms: 4-Oxo-8-[4-(4-phenylbutoxy)benzoylamino]-4H-1-benzopyran-2-carboxamide. Grades: > 95%. CAS No. 136450-10-7. Molecular formula: C27H24N2O5. Mole weight: 456.5. | |
| Pranlukast (N-{4-Oxo-2- (1H-tetrazol-5-yl) -4H-1-benzopyran-8-yl]-4- (4-phenylbutoxy) benzamide, ONO-1078, ONO-RS-411, Onon,) | A potent, selective and orally active CysLT receptor antagonist. Leukotriene antagonist. Used as an antiasthmatic. Group: Biochemicals. Alternative Names: N-{4-Oxo-2- (1H-tetrazol-5-yl) -4H-1-benzopyran-8-yl]-4- (4-phenylbutoxy) benzamide, ONO-1078, ONO-RS-411, Onon. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| 8-Amino-4-oxo-2-(tetrazol-5-yl)benzopyran | Pranlukast intermediate. Group: Biochemicals. Alternative Names: 8-Amino-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-4-one; 8-Amino-2-(2H-tetrazol-5-yl)-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 110683-22-2. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
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