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| Product | Description | |
|---|---|---|
| Prazosin hydrochloride | Prazosin hydrochloride is a well-tolerated, CNS-active α1-adrenergic receptor antagonist for the research of high blood pressure and alcohol use disorders [1]. Prazosin hydrochloride potently inhibits Norepinephrine (NE)-stimulated 45Ca efflux with an IC 50 of 0.15 nM [2].Prazosin hydrochloride inhibits organic cation transporters OCT-1 and OCT-3 with IC 50 s of 1.8, and 13 μM, respectively [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 19237-84-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0193A. |  |
| Prazosin Hydrochloride | Prazosin Hydrochloride (Terazosin EP Impurity K) is an antihypertensive. α1-Adrenergic blocker. Prazosin hydrochloride, a quinazole derivative, is a very potent and highly selective antagonist for apha-1-adrenoceptors (affinity for alpha-1 is about 1000-fold greater than for alpha-2 receptors). Mainly used as a clinic vasodilator for blood pressure control without increasing the heart rate or significantly impairing sympathetic functions. Has also been used clinically to treat anxiety, PTSD, and panic disorder. An excellent candidate for research studying brain functions mediated through alpha-1-adrenergic receptors, such as reward, pleasure, aggression, fear, anxiety, and addiction. Group: Biochemicals. Alternative Names: [4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-2-furanylmethanone Hydrochloride; 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4- (2-furanylcarbonxyl) piperazine Hydrochloride; Adversuten; Adverszuten; Alpress LP; Furazosin; Lentopres; NSC 292810; Peripress; Terazosin EP Impurity K. Grades: Highly Purified. CAS No. 19237-84-4. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C??H??ClN?O?, Molecular Weight: 419.86r. US Biological Life Sciences. |  Worldwide |
| Prazosin-d8 hydrochloride | Prazosin-d8 hydrochloride is the deuterium labeled Prazosin hydrochloride. Prazosin hydrochloride is an alpha-adrenergic blocker [1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189508-34-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-B0193AS. | |
| CP 100356 | CP 100356 is a high affinity P-glycoprotein inhibitor.Ki value is 58 nM for mouse Pgp1a and 94nMfor Pgp1b isoforms. It can Inhibit calcein-AM uptake in MDR1-transfected MDCKII cells with IC50 value of 0.5 μM and prazosin transport in BCRP-transfected MDCKII cells with IC50 value of 1.5 μM. Preclinical development for Cancer in USA was discontinued. Uses: Cancer. Synonyms: CP 100356; CP100356; CP-100356; 4-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-(2-(3,4-dimethoxyphenyl)ethyl)-6,7-dimethoxy-2-Quinazolinamine; 142715-48-8(hydrochloride). Grades: >98 %. CAS No. 142716-85-6. Molecular formula: C31H36N4O6. Mole weight: 560.64. |  |
| CP-100356 Hydrochloride | CP-100356 is a specific inhibitor of MDR1 (P-Gp), the protypical ABC transporter. CP-100356 also inhibits prazosin transport in human breast cancer resistance protein (BCRP)-transfected MDCKII cells, suggesting that it acts as a dual inhibitor. CP-100356 does not inhibit multidrug resistance-associated protein 2 (MPR2 IC50 >15 mM). Group: Biochemicals. Alternative Names: 4-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-N-[2-(3,4-dimethoxyphenyl)ethyl]-6,7-dimethoxy-2-quinazolinamine Monohydrochloride. Grades: Highly Purified. CAS No. 142715-48-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Methoxamine hydrochloride | Methoxamine hydrochloride is a selective alpha1-adrenergic receptor agonist. Methoxamine hydrochloride causes vasoconstriction and increased peripheral vascular resistance [1] [2]. Methoxamine hydrochloride significantly increased the overflow of ATP, ADP and AMP, but not adenosine, by a prazosin-sensitive mechanism in the rabbit pulmonary artery [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 61-16-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-B1298. | |
| Prazosin | Prazosin, a selective and orally active antagonist of adrenergic alpha-1, is a synthetic piperazine derivative to treat high blood pressure and anxiety, PTSD, and panic disorder. Uses: Adrenergic alpha-1 receptor antagonists. Synonyms: [4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(furan-2-yl)methanone Douglas Brand of Prazosin Hydrochloride Furazosin HCL, Prazosin Hydrochloride, Prazosin Minipress Pfizer Brand of Prazosin Hydrochloride Pratsiol Prazosin Prazosin HCL Prazosin. Grades: 95%. CAS No. 19216-56-9. Molecular formula: C19H21N5O4. Mole weight: 383.40. | |
| Terazosin, Hydrochloride | An a-1-adrenergicblocker related to prazosin. Group: Biochemicals. Alternative Names: 1- (4-Amino-6, 7-dimethoxy-2-quinazolinyl) -4-[ (tetrahydro-2-furanyl) carbonxyl]piperazine, Hydrochloride. Grades: Highly Purified. CAS No. 63074-08-8. Pack Sizes: 1g, 5g. US Biological Life Sciences. | Worldwide |
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