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| Product | Description | |
|---|---|---|
| Pristinamycin IIA | Pristinamycin IIA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Uses: Anti-bacterial agents. Synonyms: virginiamycin M1; Streptogramin A; Mikamycin A; Ostreogrycin a. Grades: ≥ 95%. CAS No. 21411-53-0. Molecular formula: C28H35N3O7. Mole weight: 525.59. |  |
| Ostreogrycin A (Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M) | Ostreogrycin A also commonly referred to as virginiamycin M1 or streptogramin A is the major component of the "virginamycin complex". In the 1950s this complex was independently discovered so many times the literature became highly confusing. Ostreogrycin A is a macrocyclic lactone antibiotic that acts syngeristically with the structurally unrelated cyclic depsipeptides more commonly known as the virginiamycins B (ostreogrycin B or streptogramin B) and S to inhibit peptide elongation. This is achieved by blocking formation of a peptide bond between the growing peptide chain (peptidyl-tRNA) linked to the 50S ribosome and aminoacyl-tRNA. Ostreogrycin A has proven to be highly active against Gram positive bacteria, particularly methicillin-resistant S. aureus. Group: Biochemicals. Alternative Names: Mikamycin A, Pristinamycin IIA, Stephylomycin M1, Streptogramin A, Syncothrecin A, Synergistin A1, Virginiamycin M1, Vernamycin A, Antibiotic 14752-2, Antibiotic E129A, Antibiotic PA 114A, Antibiotic 1745Z3A, Antibiotic 547C, Factor M. Grades: Highly Purified. CAS No. 21411-53-0. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Dalfopristin | A semi-synthetic analogue of ostreogrycin A (virginiamycin M, pristinamycin IIA, streptogramin A) formed by addition of diethylaminoethylthiol to the 2-pyrroline group of ostreogrycin, followed by oxidation to the sulphone. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Dalfopristin is used commercially in synergistic combination with quinupristin (70:30). There is little published data on the synthesis, biological or antibiotic activity of dalfopristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains. Synonyms: Dalfopristinum. Grades: >98% by HPLC. CAS No. 112362-50-2. Molecular formula: C34H50N4O9S. Mole weight: 690.85. | |
| Pristinamycin | Pristinamycin is a complex of antibiotics produced by streptomyces pristinaespiralis, containing two components Pristinamycin IA and Pristinamycin IIA. Pristinamycin IA is a macrolide, and Pristinamycin IIA (streptogramin A) is a depsipeptide. Pristinamycin has been indicated for the treatment of MRSA. Synonyms: Pyostacine; Stafac; Pristinamycine; Staphylomycin; Virginiamycin. CAS No. 270076-60-3. Molecular formula: C73H89N11O17. Mole weight: 1392.55. | |
| Virginiamycin M1 | Virginiamycin M1 (Pristinamycin IIA; Ostreogrycin A), produced by Streptomyces virginiae , is an polyunsaturated macrocyclic lactone antibiotic and acts as a component of Virginiamycin (HY-112665) [1]. Virginiamycin M1 alone is against Staphylococcus aureus with a MIC of 0.25 μg/mL. Uses: Scientific research. Group: Natural products. Alternative Names: Pristinamycin IIA; Ostreogrycin A. CAS No. 21411-53-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N6686. |  |
| Virginiamycin M1 | Virginiamycin M1. Uses: For analytical and research use. Group: Pharma & vet compounds & metabolites; pharma & vet compounds & metabolites. Alternative Names: NSC 87432, (3R,4R,5E,10E,12E,14S)-8,9,14,15,24,25-Hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, Factor M, RP 12536, [3R-(3R*,4R*,5E,10E,12E,14S*)]-8,9,14,15,24,25-Hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, NSC 244426, Ostreogrycin A (7CI), PA 114A, Virginiamycin M1, Mikamycin A (6CI,8CI), Antibiotic PA 114A1, Pristinamycin IIA,3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 8,9,14,15,24,25-hexahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S)-, Staphylomycin M1, Pristinamycin II, Factor M (antibiotic), Antibiotic PA 114A, Streptogramin A, Vernamycin A. CAS No. 21411-53-0. Molecular formula: C28H35N3O7. Mole weight: 525.59. Catalog: APS21411530A. SMILES: CC(C)[C@H]1OC(=O)C2=CCCN2C(=O)c3coc(CC(=O)C[C@H](O)\C=C(/C)\C=C\CNC(=O)\C=C\[C@H]1C)n3. Format: Neat. |  |
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