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Procyanidin A1 is found in cinnamon and is extracted from the herbs of Daemonorops draco. It is an epicatechin-(2β?7,4β?8)-catechin dimer and is potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone. It inhibits LDL oxidation with the IC50 value of 0.94 uM. It also inhibits degranulation downstream of protein kinase C activation or Ca2? influx from an internal store in RBL-2H3 cells. It shows antiallergic effects. Synonyms: Proanthocyanidin A1; Epicatechin-(2b->7,4b->8)-catechin; (2R,3S,8S,14R,15R)-2,8-Bis(3,4-dihydroxyphenyl)-3,4-dihydro-8,14-methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol. Grades: 97.5%. CAS No. 103883-03-0. Molecular formula: C30H24O12. Mole weight: 576.50.
Procyanidin A2
Botanical Source: Group: Biochemicals. Alternative Names: Proanthocyanidin A2, Procyanidoepicatechin. Grades: Plant Grade. CAS No. 41743-41-3. Pack Sizes: 10mg, 20mg. US Biological Life Sciences.
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Procyanidin A2
Procyanidin A2 is a flavonoid found in grapes, with anti-cancer, antioxidant, antimicrobial and anti-inflammation activity [1] [2]. Uses: Scientific research. Group: Natural products. CAS No. 41743-41-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2343.
Procyanidin B1
Procyanidin B1. Group: Biochemicals. Alternative Names: (2R,2'R,3R,3'S,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-[4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol; (-)-Epicatechin-(4 β-8)-(+)-catechin; Proanthocyanidin B1; Procyanidol B1. Grades: Highly Purified. CAS No. 20315-25-7. Pack Sizes: 500ug. Molecular Formula: C30H26O12, Molecular Weight: 578.52. US Biological Life Sciences.
Worldwide
Procyanidin B1
Procyanidin B1 is a procyanidin dimer found in Cinnamomum verum, in Uncaria guianensis, and in Vitis vinifera or in peach. Procyanidin B1 (PB1) inhibits infection by vesicular stomatitis virus and HCV pseudotype virus in Huh-7 cells, with 50% effective concentrations of 29 and 15 μM, respectively. No inhibitory effects were observed in each component of PB1. PB1 does not interfere with viral entry or receptor expression, but inhibits HCV RNA synthesis in a dose-dependent manner. Uses: Antioxidant;anti-inflammatory. Synonyms: Proanthocyanidin B1; Endotelon; Procyanidin dimer B1. Grades: >98%. CAS No. 20315-25-7. Molecular formula: C30H26O12. Mole weight: 578.52.
Procyanidin B2
Procyanidin B2 is a natural flavonoid, with anti-cancer, antioxidant activities. Uses: Scientific research. Group: Natural products. Alternative Names: Proanthocyanidin B2. CAS No. 29106-49-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N0796.
Procyanidin B2
Procyanidin B2 is a selective protein kinase C inhibitor and was also found to promote hair epithelial cell growth and stimulate anagen induction. Procyanidin B2 extracted from apples have also shown anti-inflammatory activities. Group: Biochemicals. Alternative Names: (2R,2'R,3R,3'R,4R)-2,2'-bis(3,4-dihydroxyphenyl)-3,3',4,4'-tetrahydro-[4,8'-Bi-2H-1-benzopyran]-3,3',5,5',7,7'-hexol. Grades: Highly Purified. CAS No. 29106-49-8. Pack Sizes: 1mg, 2mg, 5mg. Molecular Formula: C30H26O12, Molecular Weight: 578.52. US Biological Life Sciences.
Procyanidin B3 is a natural product, acts as a specific HAT inhibitor, binds to the other site of p300 instead of the active site, selectively inhibits p300-mediated androgen receptor acetylation. Procyanidin B3 has no effect on HDAC or HMT (histone methyltransferase). Group: Inhibitors. Alternative Names: PROCYANIDIN B3; CATECHIN-(4ALPHA->8)-CATECHIN; CATECHIN-(4ALPHA->8)-CATECHIN B3;procyanidin B3 from barley;(2R,2R,3S,3S,4S)-2,2-Bis(3,4-dihydroxyphenyl)-4,8-bichroman-3,3,5,5,7,7-hexol;(2R,2R,3S,3S,4α)-3,3,4,4-Tetrahydro-2α,2α-bis(3,4-dihydroxyphenyl)-4,8-bi[2H-1-benzopyran]-3,3,5,5,7,7-hexol;3,3,4,4-Tetrahydro-2α,2α-bis(3,4-dihydroxyphenyl)-4α,8-bi[2H-1-benzopyran]-3β,3β,5,5,7,7-hexol;(2R,2R,3S,3S,4S)-2,2-Bis(3,4-dihydroxyphenyl)-3,3,4,4-tetrahydro-[4,8-bi-2H-1-benzopyran]-3,3,5,5,7,7-hexol. CAS No. 23567-23-9. Molecular formula: C30H26O12. Mole weight: 578.52. Appearance: Solid. Purity: 0.9963. Canonical SMILES: O[C@@H]1[C@@H] (C2=CC=C (O)C (O)=C2)OC3=CC (O)=CC (O)=C3[C@H]1C4=C5C (C[C@H] (O)[C@@H] (C6=CC=C (O)C (O)=C6)O5)=C (O)C=C4O. Density: 1.705. Catalog: ACM23567239.
Procyanidin B3
Procyanidin B3 is a natural product with antioxidant activity and oral bioavailability, possessing good blood-brain barrier penetration. Procyanidin B3 is a selective inhibitor of histone acetyltransferase ( HAT ). By inhibiting p300 HAT -mediated acetylation of the androgen receptor ( androgen receptor ). Procyanidin B3 alleviates intervertebral disc degeneration (IVDD) by inhibiting the formation of the TLR4/MD-2 complex. Procyanidin B3 can be used in research on prostate cancer and arthritis [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 23567-23-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-N2345.
Procyanidin C1 is extracted from the fruits of Vitis vinifera L. It is a B type proanthocyanidin and found in grape. It belongs to a polyphenol flavonoid epicatechin trimer. It can decrease cytokine production of mast cells and Fc epsilon RI-mediated degranulation in vitro dose-dependently. It inhibits ROS generation in stimulated mast cells and the tyrosine phosphorylation of Syk and linker for activation of T cells. It may be used for the treatment of cardiovascular diseases and may be useful as a lead compound to develop inhibitors of cancer metastasis and other diseases related to EMT. It has HIV-related, antioxidant and anti-inflammatory effects. It also inhibits the activity of 15-lipoxygenase and α-glucosidase. It could scavenge 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radicals. Synonyms: Procyanidol C1; (2R,2'R,2''R,3R,3'R,3''R,4R,4'S)-2,2',2''-tris(3,4-dihydroxyphenyl)-3,3',3'',4,4',4''-hexahydro-[4,8':4',8''-ter-2H-1-benzopyran]-3,3',3'',5,5',5'',7,7',7''-nonol; Proanthocyanidin C1; Cinnamtannin A1; [Epicatechin-(4beta->8)]2-epicatechin. Grades: 97.5%. CAS No. 37064-30-5. Molecular formula: C45H38O18. Mole weight: 866.77.
Procyanidin C1
Procyanidin C1 (PCC1), a natural polyphenol with oral activity, causes DNA damage, cell cycle arrest and induces apoptosis. Procyanidin C1 decreases the level of Bcl-2, but enhances BAX, caspase 3 and 9 expression in cancer cells. Procyanidin C1 shows senotherapeutic activity and increases lifespan in mice [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: PCC1. CAS No. 37064-30-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N2342.
Procyanidin C2
Procyanidin C2 is a proanthocyanidin trimer isolated from grape seeds (Vitis vinifera), in Pinus radiata, in Potentilla viscosa and so on. Grades: > 95%. CAS No. 37064-31-6. Molecular formula: C45H38O18. Mole weight: 866.77.
(2R, 2'R, 3R, 3'R, 4R)-2, 2'-Bis[3, 4-bis (phenylmethoxy)phenyl]-3, 3', 4, 4'-tetrahydro-5, 5', 7, 7'-tetrakis (phenylmethoxy)[4, 8'-bi-2H-1-benzopyran]-3, 3'-diyl Ester 3,4,5-Tris(phenylmethoxy)-benzoic Acid is an intermediate in the synthesis of Procyanidin B2 3,3'-Di-O-gallate (P755825). Procyanidin B2 3,3'-di-O-gallate is an important compound whose activity results in the inhibition of growth pertaining to human prostate carcinoma cell lines. Coming from the group of compounds known as flavonoids, Procyanidin B2 3,3'-di-O-gallate shows interesting biological activities relating to various human cancer diseases. Group: Biochemicals. Grades: Highly Purified. CAS No. 223387-33-5. Pack Sizes: 500ug, 1mg. Molecular Formula: C142H118O20. US Biological Life Sciences.
Worldwide
3- (3-Hydroxyphenyl) propionic Acid
3-Hydroxyphenylpropionic Acid was found as an urinary metabolite of Procyanidins in pigs. 3-Hydroxyphenylpropionic Acid is also an intermediate in the synthesis of various organic synthetic products. Group: Biochemicals. Alternative Names: Dihydro-m-coumaric Acid; NSC 33135; NSC 39468; m-Hydroxyphenylpropionic Acid; β - (3-Hydroxyphenyl) propionic Acid; β - (m-Hydroxyphenyl) propionic Acid; 3- (3-Hydroxyphenyl) propanoic Acid; 3-Hydroxyphenyl) propionic Acid; 3- (m-Hydroxyphenyl) propionic Acid; 3-Hydroxy Benzene propanoic Acid; 3-Hydroxydihydrocinnamic Acid; m-Hydroxyhydrocinnamic Acid; 3-Hydroxy Benzene propanoic Acid. Grades: Highly Purified. CAS No. 621-54-5. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Hawthorn Extract
Hawthorn extract is prepared from the fruit of Crataegus species, a small tree or shrub and a member of the rose family. Hawthorn berry extract powder contains various compounds such as procyanidins, flavonoids and flavonols that exhibit antioxidant properties. Hawthorn berry extract is used to promote the health of the circulatory system, treat angina, high blood pressure, congestive heart failure and cardiac arrhythmia. Group: Others. Mole weight: 578.52. Hawthorn Extract; Crataegus pinnatifida Bge. Cat No: EXTC-015.
Proanthocyanidin A4
Proanthocyanidin A4 is a Procyanidin isolated from the root of E. sinica. It shows anti-inflammatory effects. Synonyms: 8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol, 2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, (2S,3R,8S,14R,15R)-; (2S,3R,8S,14R,15R)-2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-2H,14H-8,14-methanobenzo[7,8][1,3]dioxocino[4,5-h]chromene-3,5,11,13,15-pentol; (+)-Epicatechin-(4β-8,2β-O-7)-(-)-catechin, Proanthocyanidin A4. Grades: ≥95%. CAS No. 111466-29-6. Molecular formula: C30H24O12. Mole weight: 576.51.
Proanthocyanidins
Proanthocyanidin (Procyanidin) are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy. [1]. Uses: Scientific research. Group: Natural products. CAS No. 20347-71-1. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0794.
Procyanidol B4
Procyanidol B4 is a flavonoid with antioxidant and anti-inflammatory properties. Synonyms: Procyanidin B4. Grades: 98%. CAS No. 29106-51-2. Molecular formula: C30H26O12. Mole weight: 578.5.
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