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| Product | Description | |
|---|---|---|
| Prodigiosin | It is an antibiotic produced by Serratia marcescens HY-3 and Ser. marinorubra. It has a broad biological profile with activity against fungi, tumour cell lines and malaria. It also acts as an inducer of p21WAF1/CIP1 expression via transforming growth factor-β receptor pathway, and activates NAG-1 via glycogen synthase kinase-3&beta. Synonyms: (2Z,5Z)-4-methoxy-5-((5-methyl-4-pentyl-1H-pyrrol-2-yl)methylene)-1,5-dihydro-2,2'-bipyrrolylidene. Grades: >95% by HPLC. CAS No. 82-89-3. Molecular formula: C20H25N3O. Mole weight: 323.43. |  |
| Prodigiosin | Prodigiosin is an intensely red pyrrole pigment produced by several bacteria, most notably, Serratia marcescens. Prodigiosin has a broad biological profile with activity against fungi, tumor cell lines and malaria. It was shown to be an immunosuppressant in 2007. The mode of action of prodigiosin has recently received considerable attention as an inducer of apoptosis in human primary cancer cells via caspase activation. Prodigiosin also acts as an inducer of p21WAF1/CIP1 expression via transforming growth factor-B receptor pathway, and of NAG-1activation by acting on glycogen synthase kinase-3B. Group: Biochemicals. Grades: Highly Purified. CAS No. 82-89-3. Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
| Prodigiosin | Prodigiosin (Prodigiosine) is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin is a potent inhibitor of the Wnt/β-catenin pathway. Prodigiosin has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Prodigiosine; NSC47147. CAS No. 82-89-3. Pack Sizes: 10 mM * 1 mL; 100 μg; 250 μg; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-100711. |  |
| Prodigiosin hydrochloride | from Serratia marcescens, ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. |  |
| Prodigiosin hydrochloride | Prodigiosin is an antibiotic from Serratia marcescens and other bacteria. It has a wide range of biological activities, including antimalarial, antifungal, anticancer and immunosuppressant properties. Synonyms: 2,2'-Bi-1H-pyrrole, 4-methoxy-5-[(5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl]?-, hydrochloride (1:1); 4-Methoxy-5-((5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl)-1H,1'H-2,2'-bipyrrole hydrochloride; 2H-Pyrrole, 2-[(4-methoxy[2,2'-bi-1H-pyrrol]-5-yl)methylene]-5-methyl-4-pentyl-, (2Z)-, hydrochloride (1:1). Grades: ≥98%. CAS No. 56144-17-3. Molecular formula: C20H25N3O.HCl. Mole weight: 359.89. | |
| Prodigiosin hydrochloride | Prodigiosin (Prodigiosine) hydrochloride is a red pigment produced by bacteria as a bioactive secondary metabolite. Prodigiosin hydrochloride is a potent proapoptotic agent, and inhibits Wnt/β-catenin pathway. Prodigiosin hydrochloride has antibacterial, antifungal, antiprotozoal, antimalarial, immunosuppressive, and anticancer properties [1] [2]. Uses: Scientific research. Group: Natural products. Alternative Names: Prodigiosine hydrochloride. CAS No. 56144-17-3. Pack Sizes: 100 μg; 250 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-100711A. | |
| Prodigiosin (NSC 47147, BRN 4526727) | Red-pigmented antibiotic. Antimalarial. Immunosuppressive. Apoptosis inducer. Cytotoxic. Induces phosphorylation of p38-MAPK. Antimetastatic. Tumor invasion inhibitor. Induces p21WAF1/CIP1 expression. Anticancer compound. gp91(phox) and iNOS expression inhibitor. mTORC1 and mTORC2 complexe inhibitor. Down-regulates SKP2 to induce p27(KIP1) stabilization. Source:Isolated from γ-proteobacterium strain MS-02-063. Group: Biochemicals. Alternative Names: NSC 47147, BRN 4526727. Grades: Highly Purified. CAS No. 82-89-3. Pack Sizes: 250ug, 1mg. Molecular Formula: C20H25N3O, Molecular Weight: 323.4. US Biological Life Sciences. | Worldwide |
| Prodigiosin Serratia marcescens - CAS 82-89-3 | A cell-permeable tripyrrole alkaloid compound that displays immunosuppressive and anti-tumor properties irrespective of p53 status and multidrug resistance. Group: Fluorescence/luminescence spectroscopy. | |
| Prodigiosin, Serratia marcescens (NSC 47147, Casein Kinase I Inhibitor IV, 2-Methyl-3-pentyl-6-methoxyprodigiosene) | A cell-permeable tripyrrole alkaloid compound that displays immunosuppressive and anti-tumor properties irrespective of p53 status and multidrug resistance. Shown to selectively upregulate p21WAF/CIP1 and NAG-1 (nonsteroidal anti-inflammatory drug-activated gene 1) and downregulate survivin expression levels, induce mitochondria-mediated apoptosis and cell cycle arrest in tumor cells. Prevents FADD phosphorylation (IC50=2.0uM in A549-FKR cells) through inhibition of FADD-kinase CK1a (IC50 ~6.0uM in SW620-BGCR cells) and augments cisplatin -induced apoptosis. Blocks NF-kB activation by decreasing plkBa (by 63% at 3uM) and lkBa levels in A549 cells, and shrinks tumor growth in A549-FKR tumor xenograft mouse model (3mg/kg, i.p., o.d.). Group: Biochemicals. Grades: Highly Purified. CAS No. 82-89-3. Pack Sizes: 200ug. US Biological Life Sciences. | Worldwide |
| Butyl cycloheptyl prodigiosin (Butyl -ortho-cycloheptyl prodiginine) | Tripyrrolic pigment like prodigiosin. Antimalarial agent. Anticancer agent with multiple modes of action. Immunosuppressant in non-toxic concentrations. Bone resorption inhibitor. Antiulcer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 352304-41-7. Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| Undecylprodigiosin | Undecylprodigiosin is a prodigiosin antibiotic. Grades: >98%. CAS No. 52340-48-4. Molecular formula: C25H35N3O. Mole weight: 393.56. | |
| Undecylprodigiosin (Undecylprodiginine, Prodigiosin 25C) | Tripyrrolic pigment like prodigiosin. Antimalarial agent. Apoptosis inducer. Anticancer agent with multiple modes of action. Immunosuppressant in non-toxic concentrations. Bone resorption inhibitor. Antiulcer agent. Group: Biochemicals. Grades: Highly Purified. CAS No. 56247-02-0, 52340-48-4 (parent). Pack Sizes: 250ug, 1mg. US Biological Life Sciences. | Worldwide |
| 3-acetyloctanal synthase | Requires thiamine diphosphate. The enzyme, characterized from the bacterium Serratia marcescens, participates in the biosynthesis of the antibiotic prodigiosin. The enzyme decarboxylates pyruvate, followed by attack of the resulting two-carbon fragment on (E)-oct-2-enal, resulting in a Stetter reaction. In vitro the enzyme can act on a number of α,β-unsaturated carbonyl compounds, including aldehydes and ketones, and can catalyse both 1-2 and 1-4 carboligations depending on the substrate. Group: Enzymes. Synonyms: pigD (gene name). Enzyme Commission Number: EC 2.2.1.12. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2028; 3-acetyloctanal synthase; EC 2.2.1.12; pigD (gene name). Cat No: EXWM-2028. |  |
| Cyclononylprodiginine | Cyclononylprodiginine is a prodigiosin antibiotic. CAS No. 34852-35-2. Molecular formula: C23H29N3O. Mole weight: 363.49. | |
| Methylcyclodecylprodiginine | Methylcyclodecylprodiginine is a prodigiosin antibiotic. CAS No. 34852-33-0. Molecular formula: C25H33N3O. Mole weight: 391.55. | |
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