Protein Kinase Suppliers USA
Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
Product | Description | |
---|---|---|
Protein Kinase C, alpha, primers, amplimer 324bp (AAG6, MGC129900, MGC129901, PKCA, PKC-A, PKC-alpha, PRKACA, Protein kinase C alpha type), Primer A, Upstream Primer Quick inquiry Where to buy Suppliers range | Protein Kinase C, alpha, primers, amplimer 324bp (AAG6, MGC129900, MGC129901, PKCA, PKC-A, PKC-alpha, PRKACA, Protein kinase C alpha type), Primer A, Upstream Primer. Group: Molecular Biology. Pack Sizes: 1x50ul. US Biological Life Sciences. | Worldwide |
Protein Kinase C, alpha, primers, amplimer 324bp (AAG6, MGC129900, MGC129901, PKCA, PKC-A, PKC-alpha, PRKACA, Protein kinase C alpha type), Primer B, Downstream Primer Quick inquiry Where to buy Suppliers range | Protein Kinase C, alpha, primers, amplimer 324bp (AAG6, MGC129900, MGC129901, PKCA, PKC-A, PKC-alpha, PRKACA, Protein kinase C alpha type), Primer B, Downstream Primer. Group: Molecular Biology. Pack Sizes: 1x50ul. US Biological Life Sciences. | Worldwide |
Protein Kinase Activator SC-10 (N- (n-heptyl) -5-chloro-1-naphthalene sulfonamide) Quick inquiry Where to buy Suppliers range | An activator of protein kinase C in a Ca2+-dependent manner, via a mechanism similar to that of phosphatidylserine. Group: Biochemicals. Alternative Names: N- (n-heptyl) -5-chloro-1-naphthalene sulfonamide. Grades: Molecular Biology Grade. CAS No. 102649-79-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Activator SC-9 (N- (6-phenylhexyl) -5-chloro-1-naphthalene sulfonamide) Quick inquiry Where to buy Suppliers range | Activates protein kinase C in a Ca2+-dependent manner, via a mechanism similar to that of phosphatidylserine. Group: Biochemicals. Alternative Names: N- (6-phenylhexyl) -5-chloro-1-naphthalene sulfonamide. Grades: Molecular Biology Grade. CAS No. 102649-78-5. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
Protein Kinase C 19-31 Quick inquiry Where to buy Suppliers range | Protein Kinase C (19-31), a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate peptide for testing the protein kinase C activity. Protein kinase C (PKC) is involved in controlling the function of other proteins through the phosphorylation of hydroxyl groups of serine and threonine amino acid residues on these proteins. Uses: Peptide Inhibitors. CAS No. 121545-65-1. Product ID: R1639. | |
Protein Kinase C 19-31 Quick inquiry Where to buy Suppliers range | Protein Kinase C (19-31) is a peptide inhibitor of protein kinase C (PKC) originating in the pseudo-substrate regulatory domain of PKCA (residues 19-31). Synonyms: PKC (19-31); Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val; Pseudosubstrate; L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine. Grades: 95%. CAS No. 121545-65-1. Molecular formula: C67H118N26O16. Mole weight: 1543.82. | |
Protein Kinase C 19-31 acetate Quick inquiry Where to buy Suppliers range | Protein Kinase C 19-31 acetate is a peptide inhibitor of protein kinase C (PKC) originating in the pseudo-substrate regulatory domain of PKCA (residues 19-31). It is used as a protein kinase C substrate peptide for testing the protein kinase C activity. Synonyms: PKC (19-31) acetate; H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH.CH3CO2H; L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine acetic acid. Grades: ≥95%. Molecular formula: C69H122N26O18. Mole weight: 1603.90. | |
Protein Kinase C Peptide Substrate Quick inquiry Where to buy Suppliers range | Protein Kinase C Peptide Substrate is targeted to a specific cellular compartment in a manner dependent on second messengers and on specific adapter proteins in response to extracellular signals that activate G-protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors. Protein Kinase C Peptide Substrate then regulates various physiological functions including the activation of nervous, endocrine, exocrine, inflammatory, and immune systems. Uses: Peptide Inhibitors. CAS No. 120253-69-2. Product ID: R1641. | |
Protein Kinase C Peptide Substrate Quick inquiry Where to buy Suppliers range | Protein Kinase C Peptide Substrate targets specific cell compartents and activates G protein-coupled receptors, tyrosine kinase receptors or tyrosine kinase-coupled receptors by relying on second messenger and specific adaptor proteins in response to extracellular signals. Protein Kinase C Peptide Substrate regulates a variety of physiological functions, including nervous, endocrine, exocrine, inflammatory and immune system activation. Synonyms: PKCε; PRKCE; Peptide Epsilon; PKC epsilon; H-Glu-Arg-Met-Arg-Pro-Arg-Lys-Arg-Gln-Gly-Ser-Val-Arg-Arg-Arg-Val-OH; L-alpha-glutamyl-L-arginyl-L-methionyl-L-arginyl-L-prolyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminyl-glycyl-L-seryl-L-valyl-L-arginyl-L-arginyl-L-arginyl-L-valine. Grades: 95%. CAS No. 120253-69-2. Molecular formula: C83H155N39O21S. Mole weight: 2067.43. | |
Protein Kinase C Peptide Substrate acetate Quick inquiry Where to buy Suppliers range | Protein Kinase C Peptide Substrate acetate targets specific cell compartments and activates G protein-coupled receptors, tyrosine kinase receptors, or tyrosine kinase-coupled receptors by relying on second messenger and specific adaptor proteins in response to extracellular signals. It regulates a variety of physiological functions, including nervous, endocrine, exocrine, inflammatory, and immune system activation. Synonyms: L-α-Glutamyl-L-arginyl-L-methionyl-L-arginyl-L-prolyl-L-arginyl-L-lysyl-L-arginyl-L-glutaminylglycyl-L-seryl-L-valyl-L-arginyl-L-arginyl-L-arginyl-L-valine acetate; H-Glu-Arg-Met-Arg-Pro-Arg-Lys-Arg-Gln-Gly-Ser-Val-Arg-Arg-Arg-Val-OH acetate. Grades: ≥95%. Molecular formula: C85H159N39O23S. Mole weight: 2127.52. | |
Protein kinase C zeta pseudosubstrate Quick inquiry Where to buy Suppliers range | Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Uses: Peptide Inhibitors. CAS No. 93755-85-2. Product ID: R0948. | |
Protein Kinase Inhibitor CKI-7 (PKI) (N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide) Quick inquiry Where to buy Suppliers range | A potent inhibitor against casein kinase 1 with respect to ATP. Exhibits a much weaker effect on casein kinase 2 and other protein kinases. Group: Biochemicals. Alternative Names: N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide. Grades: Molecular Biology Grade. CAS No. 120615-25-0. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor H-7 (PKI) (1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride) Quick inquiry Where to buy Suppliers range | A selective inhibitor of protein kinase C or cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Alternative Names: 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride. Grades: Molecular Biology Grade. CAS No. 108930-17-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor H-89 (PKI, N- (2-p-bromocinnamyl aminoeth yl ]-5-isoquinolinesulfonamid e ) (N- (2-p-bromocinnamyl aminoeth yl ]-5-isoquinolinesulfonamid e ) Quick inquiry Where to buy Suppliers range | Protein Kinase Inhibitors. Group: Biochemicals. Grades: Molecular Biology Grade. CAS No. 127243-85-0. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor H-8 (PKI) (N- [2-( methyl amino) ethy l ]-5-isoquinolinesulfonamid e dihydrochloride) Quick inquiry Where to buy Suppliers range | Inhibits cyclic-nucleotide-dependent protein kinases. Group: Biochemicals. Alternative Names: N- [2-( methyl amino) ethy l ]-5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 84478-11-5. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor H-9 (PKI) (N- (2-aminoethyl ) -5-isoquinolinesulfonamid e dihydrochloride) Quick inquiry Where to buy Suppliers range | Competitive inhibitor of protein kinase C, cGMP- and cAMP-dependent protein kinases with respect to ATP binding. Group: Biochemicals. Alternative Names: N- (2-aminoethyl ) -5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 84468-17-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor HA1004 (PKI) (N- (2-guanidinoethyl ] -5-isoquinolinesulfonamid e dihydrochloride) Quick inquiry Where to buy Suppliers range | Calcium antagonist and vasodilator. Does not affect on cardiac function. Group: Biochemicals. Alternative Names: N- (2-guanidinoethyl ] -5-isoquinolinesulfonamid e dihydrochloride. Grades: Molecular Biology Grade. CAS No. 92564-34-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor ML-7 (PKI) (1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) Quick inquiry Where to buy Suppliers range | Inhibits myosin light chain kinase. Group: Biochemicals. Alternative Names: 1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride. Grades: Molecular Biology Grade. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitor ML-9 (PKI) (1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) Quick inquiry Where to buy Suppliers range | Competitive inhibitor of several protein kinases wrt ATP. Group: Biochemicals. Alternative Names: 1-(5-Chloronaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride. Grades: Molecular Biology Grade. CAS No. 105637-50-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Protein Kinase Inhibitors 1 Quick inquiry Where to buy Suppliers range | Protein Kinase Inhibitors 1 is a HIPK2 inhibitor with IC50 of 74 nM and Kd of 9.5 nM. Synonyms: 2,4-Thiazolidinedione, 5-[[1,2-dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-; 5-((2-oxo-6'-(piperazin-1-yl)-1,2-dihydro-[3,3'-bipyridin]-5-yl)methylene)thiazolidine-2,4-dione; 5-[[1,2-Dihydro-2-oxo-6'-(1-piperazinyl)[3,3'-bipyridin]-5-yl]methylene]-2,4-thiazolidinedione. Grades: ≥95%. CAS No. 1365986-44-2. Molecular formula: C18H17N5O3S. Mole weight: 383.43. | |
SRPK Inhibitor, SRPIN340 (N- (2-Piperidin-1-yl-5- (trifluoromethyl) phenyl) isonicotinamide, Serine-Arginine-Rich Protein Kinase Inhibitor, SR Protein Kinase Inhibitor, SR Protein Phosphorylation Inhibitor 340, (SRPIN)340) Quick inquiry Where to buy Suppliers range | A cell-permeable isonicotinamide that acts as an ATP-competitive SRPK1-selective inhibitor (IC50 = 0.14 and 1.8uM, respectively, against mSRPK1 and mSRPK2) with much reduced activity against 143 other kinases. Shown to effectively counteract IGF-1-induced anti-angiogenic to pro-angiogenic VEGF isoforms switch both in cultures in vitro (1h 10uM SRPIN340 prior to 12h IGF-1 stimulation of PCIPs) and in a murine hypoxia-induced retinal neovascularization model in vivo (10pmol/uL/eye intraocular SRPIN340 injection) by inhibiting PKC/SRPK signaling-dependent, alternate splicing factor ASF- (SF2; splicing factor 2) mediated VEGF pro-mRNA PSS (proximal splice site) selection. Suppresses RNA virus Sindbis propagation (IC50 = 60uM in Vero cultures) and HCV-JFH1 replication (1 & 10uM SRPIN340 in Huh7.5.1 cultures). Exhibits no toxicity toward rats (2g/kg p.o. for 2 wks), CHO (5mg/ml for 24h), or Huh7 (30uM for 48h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
PKR Inhibitor III, 7DG (Double-stranded RNA-activated Protein Kinase Inhibitor III, EIF2AK2 Inhibitor III, 7-Desacetoxy-6,7-dehydrogedunin, Double-stranded RNA-dependent Protein Kinase Inhibitor III) Quick inquiry Where to buy Suppliers range | A cell-permeable gedunin analog that directly targets PKR via reversible interaction inhibits PKR-mediated cellular events by disrupting PKR signaling complexes assembly, such as IkK complex and inflammasome / pyroptosome, resulting in effective blockage of LPS-induced IkBbeta degradaion (20uM) and protection against anthrax toxin LT-induced caspase-1 activation as well as subsequent pyroptosis (10uM) in murine macrophage J774 cultures. PKR is also known to mediate LT-induced apoptosis via its kinase activity in LPS-primed Macrophages derived from C57BL/6 with a resistent NLRP1 allele, inhibitable by C16, but not by 7DG, while LT-induced pyroptosis in J774 cultures is insensitive to C16 treatment. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??O?. US Biological Life Sciences. | Worldwide |
MAP Kinase p38, Control Cell Extracts (Mitogen Activated Protein Kinase p38, MAPK p38) Quick inquiry Where to buy Suppliers range | P38 MAP kinase (MAPK), also called RK (3) or CSBP (2), is the mammalian homologue of the yeast HOG kinase and participates in a signaling cascade controlling cellular responses to cytokines and stress (1-4). Four isoforms of p38 MAP kinase, alpha, beta, gamma and delta, have been identified so far. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including osmotic shock, inflammatory cytokines, lipopolysaccharides (LPS), UV light and growth factors (1-5). MKK3 and SEK activate p38 MAP kinase by phosphorylation at threonine 180 and tyrosine 182. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase 2 (3) and to phosphorylate the transcription factors ATF-2 (5), Max (6) and MEF2 (5-8). Nonphosphorylated p38 MAP Kinase Control Cell. Group: Biologicals. Alternative Names: EC=2.7.11.24. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences. | Worldwide |
Haspin Kinase Inhibitor, CHR-6494 (3-(1H-Indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine, Haploid Germ Cell-Specific Nuclear Protein Kinase Inhibitor, CHR-6494, Indazolyl-propylimidazopyridazin-amine) Quick inquiry Where to buy Suppliers range | A cell-permeable indazolyl imidazopyridazinamine compound that acts as a potent and reversible inhibitor of histone kinase haspin activity (IC50 = 2nM) with moderate selectivity over TrkA, GSK-3beta, PIM1, Cdk1/B and Cdk2/A (% inhibition at 100nM = 58, 48, 36, 34 and 33, respectively) among a panel of 27-kinases. Shown to block pH3-Thr3, with no effect on pH3-Ser10 and pH3-Ser28, cause mitotic catastrophe, upregulate BUB1 and cyclin B1 levels, and potently induce apoptosis (IC50 = 473, 500 and 752nM in HeLa, HCT-116 and MDA-MB-231 cells, respectively). Further, efficiently blocks bFGF-induced sprouting vessel by 70% at 1uM (chicken embryo aortic arch ring assay) and suppresses tumor growth in HCT-116 xenografted mouse model (50mg/kg, i.p.). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Calmodulin-Dependent Protein Kinase II 281-309 Quick inquiry Where to buy Suppliers range | Calmodulin-Dependent Protein Kinase II (281-309) is a peptide of calcium/calmodulin-dependent protein kinase II (CaM-kinase II). Uses: Peptide Inhibitors. CAS No. 116826-37-0. Product ID: R1267. | |
Calmodulin-Dependent Protein Kinase II 290-309 Quick inquiry Where to buy Suppliers range | Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II. Uses: Peptide Inhibitors. CAS No. 115044-69-4. Product ID: R1268. | |
Calmodulin-Dependent Protein Kinase II 290-309 Quick inquiry Where to buy Suppliers range | Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with IC50 of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. It has been used in the study of CaM binding, autophosphorylatio and dynamics. Synonyms: Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala; L-leucyl-L-lysyl-L-lysyl-L-phenylalanyl-L-asparagyl-L-alanyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-lysyl-glycyl-L-alanyl-L-isoleucyl-L-leucyl-L-threonyl-L-threonyl-L-methionyl-L-leucyl-L-alanine; CaM kinase II (290-309); Calmodulin-dependent Protein Kinase II fragment 290-309. Grades: ≥97% by HPLC. CAS No. 115044-69-4. Molecular formula: C103H185N31O24S. Mole weight: 2273.83. | |
Calmodulin-Dependent Protein Kinase II (290-309) trifluoroacetate salt Quick inquiry Where to buy Suppliers range | Calmodulin-dependent protein kinase II (290-309) is a synthetic peptide derived from the rat brain protein sequence that contains the calmodulin binding domain. It inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) with an IC50 value of 52 nM and CaMKII-dependent phosphodiesterase activity with IC50 of 1.1 nM. Calmodulin-dependent protein kinase II (290-309) has been used in the study of CaM binding, autophosphorylation, and dynamics. Grades: ≥95%. Molecular formula: C103H185N31O24S·xCF3COOH. Mole weight: 2273.83. | |
Calmodulin-dependent Protein Kinase II fragment 290-309 Quick inquiry Where to buy Suppliers range | ≥97% (HPLC). Uses: For analytical and research use. Group: Fluorescence/Luminescence Spectroscopy. CAS No. 115044-69-4. Pack Sizes: 1MG. Mole weight: 2273.83. Catalog: AP115044694-B. Assay: ≥97% (HPLC). | |
CaMKII Inhibitor XII (Ca2+/Calmodulin-Dependent Protein Kinase II Inhibitor XII) Quick inquiry Where to buy Suppliers range | A pyrimidinyl sulfonamide compound that acts as a potent, reversible and CaM non-competitive inhibitor of CaMKII activities (IC50 = 0.063uM) with excellent selectivity over several kinases (IC50 = >60, 36, 11, 30 and 21uM for CaMKIV, MLCK, p38alpha, Akt1 and PKC, respectively). Shown to exhibit ~25-fold greater potency towards CaMKII than the CaM-competitive inhibitor KN-93. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
Casein from milk, suitable for substrate for protein kinase (after dephosphorylation) Quick inquiry Where to buy Suppliers range | In milk, casein exists as a calcium salt, forming micellar particles surrounded by soluble kappa-casein. The casein component of milk is relatively thermally stable and can withstand temperatures of 62-71°C, while the whey protein component denatures at this temperature. Casein is digested slowly in organisms and coagulates in the stomach, resulting in anti-catabolic properties of casein. Casein is a large, firm, dense curd that is extremely difficult to digest. There are four different types of casein, each with a different genetic variation. They are α-s1 casein, α-s2 casein, β-casein and κ-casein, respectively. Uses: ·Nutritional supplements ·Raw material of food ·Paint, wood glue, plastic fiber ·Dentist Materials. Group: Animal Hydrocolloids. CAS No. 9000-71-9. Molecular Weight: 2061.96 g/mol. Boiling Point: 280 °C (dec.) (lit.). Flash Point: ≥70 %. Purity: 1.26 g/cm3. Density: H2O: insoluble, forms a cloudy suspension. | |
CID 2011756 (Pan Protein Kinase D (PKD) Inhibitor, Cell Permeable, 5- (3-Chlorophenyl) -N-[4- (4-morpholinylmethyl) phenyl]-2-furancarboxamide) Quick inquiry Where to buy Suppliers range | Protein kinase D (PKD) inhibitor (IC50 values are 0.6, 0.7 and 3.2um for PKD2, PKD3 and PKD1 respectively). Cell permeable (EC50=10um for PKD1 inhibition). ATP-competitive. Group: Biochemicals. Grades: Highly Purified. CAS No. 638156-11-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
DNA-dependent protein kinase catalytic subunit (2836-2844) Quick inquiry Where to buy Suppliers range | DNA-dependent protein kinase catalytic subunit. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-075. | |
PKC Activator VII, CGK062 (Protein Kinase C Activator VII) Quick inquiry Where to buy Suppliers range | A cell permeable coumarin-containing compound that is shown to activate PKCalpha activity and induce cellular PKCalpha membrane translocation (Effective conc. 12.5 to 50uM) as well as PKCalpha-mediated signaling events. Effectively affects the viability of CRT-dependent cancer cells (IC50 = 1.62 to 18.6uM; 48h) in vitro and suppresses PC3-derived tumor expansion in mice (50 & 100mg/kg/day; i.p) in vivo, while exhibiting little cytotoxicity toward WI38 normal fibroblasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??O?, Primary Target IC50: 12.2uM. US Biological Life Sciences. | Worldwide |
Receptor-type tyrosine-protein kinase FLT3 (591-600) Quick inquiry Where to buy Suppliers range | Receptor-type tyrosine-protein kinase FLT3. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-204. | |
Receptor-type tyrosine-protein kinase FLT3 (591-600) Quick inquiry Where to buy Suppliers range | Receptor-type tyrosine-protein kinase FLT3 (591-600) is a truncated fragment of Receptor-type tyrosine-protein kinase FLT3. Tyrosine-protein kinase acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Synonyms: FL cytokine receptor (591-600); Fetal liver kinase-2 (591-600); Fms-like tyrosine kinase 3 (591-600). | |
Receptor tyrosine-protein kinase erbB-2 (1023-1032) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-339. | |
Receptor tyrosine-protein kinase erbB-2 (369-377) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-331. | |
Receptor tyrosine-protein kinase erbB-2 (391-399) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-340. | |
Receptor tyrosine-protein kinase erbB-2 (402-410) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-341. | |
Receptor tyrosine-protein kinase erbB-2 (435-443) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-334. | |
Receptor tyrosine-protein kinase erbB-2 (466-474) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-342. | |
Receptor tyrosine-protein kinase erbB-2 (48-56) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-338. | |
Receptor tyrosine-protein kinase erbB-2 (5-13) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-333. | |
Receptor tyrosine-protein kinase erbB-2 (63-71) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-345. | |
Receptor tyrosine-protein kinase erbB-2 (650-658) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-343. | |
Receptor tyrosine-protein kinase erbB-2 (654-662) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-332. | |
Receptor tyrosine-protein kinase erbB-2 (665-673) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-336. | |
Receptor tyrosine-protein kinase erbB-2 (689-697) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-335. | |
Receptor tyrosine-protein kinase erbB-2 (754-762) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-344. | |
Receptor tyrosine-protein kinase erbB-2 (952-961) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-337. | |
Receptor tyrosine-protein kinase erbB-2 precursor (369-386) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-089. | |
Receptor tyrosine-protein kinase erbB-2 precursor (369-386) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2, is a protein that in humans is encoded by the ERBB2 gene. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients. Synonyms: CD340 precursor (369-386). | |
SAPK1, JNK (Stress Activated Protein Kinase, Jun Kinase) Control Cell Extracts Quick inquiry Where to buy Suppliers range | The SAPK/JNK pathway is homologous to the MAPK pathway in its overall form but is activated by largely distinct stimuli (1). A variety of extracellular stimuli activate the JNK/SAPK pathway including inflammatory cytokines, UV light, inhibitors of protein synthesis and osmotic stress (1-5). Inflammatory cytokines such as TNFa and IL1 appear to activate this pathway via the Rac/Rho family of small GTP binding proteins, whereas inhibitors of protein synthesis and UV light appear to act independently of Rho and Rac (6). Activated MEKK1 phosphorylates SEK1 (also known as MKK4), which in turn activates SAPK (also known as JNK). SAPK binds tightly to the N-terminal region of c-Jun and ATF-2. It phosphorylates c-Jun at Ser63 and Ser73, and ATF-2 at Thr69 and Thr71 (5). Group: Biologicals. Grades: Lysate. Pack Sizes: 10Blots. US Biological Life Sciences. | Worldwide |
Tyrosine Protein Kinase JAK 2 Phospho-Tyr8, 9 Quick inquiry Where to buy Suppliers range | Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide corresponding to amino acids 475 to 491 of mouse JAK2. CAS No. 247171-44-4. Molecular formula: C88H138N20O34P2. Mole weight: 2082.1. | |
Tyrosine Protein Kinase JAK 2 Phospho-Tyr8, 9 Quick inquiry Where to buy Suppliers range | Tyrosine Protein Kinase JAK 2 (Phospho-Tyr8, 9) is a peptide corresponding to amino acids 475 to 491 of mouse JAK2. Uses: Peptide Inhibitors. CAS No. 247171-44-4. Product ID: R1734. | |
A-kinase anchor protein 9 (1398-1407) Quick inquiry Where to buy Suppliers range | A-kinase anchor protein 9 (1398-1407) is amino acids 1398 to 1407 fragment of A-kinase anchor protein 9. AKAP-9 is a scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. Synonyms: AKAP-9 (1398-1407). | |
A-kinase anchor protein 9 (1398-1407) Quick inquiry Where to buy Suppliers range | A-kinase anchor protein 9. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-086. | |
C-Jun-amino-terminal kinase-interacting protein 2 (683-692) Quick inquiry Where to buy Suppliers range | C-Jun-amino-terminal kinase-interacting protein 2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-068. | |
FAK, Negative Control (non-phospho) Peptide (Focal Adhesion Associated Protein Tyrosine Kinase, BC3) Quick inquiry Where to buy Suppliers range | Synthetic non-phosphopeptide (~10aa) derived from the region of FAK that contains serine 910. See corresponding antibody F0019-58N1. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
FAK [pS910], Positive Control Peptide (Focal Adhesion Associated Protein Tyrosine Kinase, BC3) Quick inquiry Where to buy Suppliers range | Synthetic phosphopeptide (~10aa) derived from the region of FAK that contains serine 910. See corresponding antibody F0019-58N1. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
FAK [pY397], Negative Control Peptide, non-phospho, for F0019-58A (Focal Adhesion Associated Protein Tyrosine Kinase, BC3) Quick inquiry Where to buy Suppliers range | Peptide (linear) Content: 80 ± 4%. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
FAK [pY397], Positive Control Peptide, phospho, for F0019-58A (Focal Adhesion Associated Protein Tyrosine Kinase, BC3) Quick inquiry Where to buy Suppliers range | Peptide (linear) Content: 80 ± 4%. Group: Molecular Biology. Grades: Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Kinase(phosphorylating), protein serine/threonine Quick inquiry Where to buy Suppliers range | Kinase(phosphorylating), protein serine/threonine. Group: Heterocyclic Organic Compound. CAS No. 9026-43-1. Molecular formula: Ca. | |
MNK1/2 Inhibitor II, ETP-45835 (ETP45835?MNK Inhibitor II, Mitogen-Activated Protein Kinase-Interacting Kinase Inhibitor II) (4-(3-(Piperidin-4-yl)-1H-pyrazol-5-yl)pyridine, diHCl) Quick inquiry Where to buy Suppliers range | A cell-permeable 3,5-disubstituted pyrazolo compound that acts as a selective MNK inhibitor (IC50=646 and 575nM, respectively, against MNK1 and MNK2) with much reduced or little activity against 24 other kinases (<15% inhibition at 5uM). Reported to exhibit good aqueous solubility (>100uM at pH 7.4) and inhibit the proliferation (IC50=17uM) and cellular eIF4E Ser209 phosphorylation (IC50=4.7uM) of MV4:11 cells. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N? 2HCl. US Biological Life Sciences. | Worldwide |
FAST kinase domain-containing protein 1 isoform 1 (497-514) Quick inquiry Where to buy Suppliers range | FAST kinase domain-containing protein 1. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-149. | |
MLKL Inhibitor, Necrosulfonamide ((E)-N-(4-(N-(3-Methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide, Mixed Lineage Kinase Domain-like Protein Inhibitor, Necrosome Inhibitor II, Necrosulfonamide) Quick inquiry Where to buy Suppliers range | A cell-permeable acrylamide compound that inhibits human, but not murine, MLKL adaptor function via covalent modification of Cys86 and is more potent than Nec-1 in preventing necrotic/necroptotic death in human HT-29 (IC50 = 124nM and 2uM, respectively), being ineffective against necrosis/necroptosis in murine L929 or apoptosis in human RIP3-null Panc-1 cells. Unlike Nec-1, which prevents necrosome formation by blocking RIP1-RIP3 interaction, MLKL prevents the MLKL-RIP1-RIP3 necrosome complex from interacting with further downstream effectors. Group: Biochemicals. Grades: Highly Purified. CAS No. 432531-71-0. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?S?, Primary Target: human MLKL. US Biological Life Sciences. | Worldwide |
BMP Inhibitor III, LDN-212854 (Abl Inhibitor V, LDN212854, Bone Morphogenetic Protein Inhibitor III, PDGFR Tyrosine Kinase Inhibitor XXIV, RIP2 Inhibitor I, RIPK2 Inhibitor I, 5-(6-(4-(Piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline) Quick inquiry Where to buy Suppliers range | A cell-permeable pyrazolopyrimidinyl quinoline that is superior to Dorsomorphin and DMH1 as an ATP-site-targeting, ALK1/2 inhibitor (IC50 = 2.40 and 1.30nM, respectively; [ATP] = 6uM) with respect to both potency and selectivity over ALK3/4/5 (IC50 = 0.858, 2.133, and 9.276uM, respectively). Also a potent RIPK2 inhibitor (IC50 = 6nM) with reduced potency against ABL1/c-abl, PDGFR-beta, ALK3, and PDGFR-alpha (IC50 = 40, 68, 85.8, and 650nM, respectively) and little inhibitory activity toward a panel of more than 190 kinases. Effectively inhibits ALK2- and ALK3-mediated C2C12 osteogenic differentiation (IC50 = 10 and 40.5nM, respectively) in vitro and prevents constitutively active ALK2 Q207D mutant-induced heterotopic ossification in mice (6mg/kg/12h via i.p.) in vivo. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C??H??N?. US Biological Life Sciences. | Worldwide |
10-DEBC hydrochloride Quick inquiry Where to buy Suppliers range | 10-DEBC hydrochloride is a selective and reversible Akt/PKB inhibitor suppressing the IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μM), and inhibiting downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. 10-DEBC hydrochloride inhibits cell growth (IC50 ~ 2-6 μM) and leads to apoptosis in rhabdomyosarcoma cells. Synonyms: 10H-Phenoxazine-10-butanamine, 2-chloro-N,N-diethyl-, hydrochloride (1:1); Akt Inhibitor X; 2-Chloro-N,N-diethyl-10H-phenoxazine-10-butanamine hydrochloride; 10-[4'-(N,N-Diethylamino)butyl]-2-chlorophenoxazine hydrochloride; 4-(2-chloro-10H-phenoxazin-10-yl)-N,N-diethylbutan-1-amine hydrochloride. Grades: ≥99% by HPLC. CAS No. 925681-41-0. Molecular formula: C20H25N2OCl.HCl. Mole weight: 381.34. | |
10-DEBC hydrochloride Quick inquiry Where to buy Suppliers range | Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5uM), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC50 ~ 2-6uM) and induces apoptosis in rhabdomyosarcoma cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 925681-41-0. Pack Sizes: 10mg, 50mg. Molecular Formula: C20H25N2OCl.HCl, Method for Determining. US Biological Life Sciences. | Worldwide |