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| Product | Description | |
|---|---|---|
| Protopanaxadiol, 20S- | Protopanaxadiol, 20S-. Group: Biochemicals. CAS No. 30636-90-9. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| protopanaxadiol 6-hydroxylase | A heme-thiolate protein (P-450). Involved in the biosynthetic pathway of ginsenosides. Isolated from the rhizomes of ginseng (Panax ginseng). Group: Enzymes. Synonyms: protopanaxatriol synthase; P6H; CYP716A53v2; protopanaxadiol,NADPH:O2 oxidoreductase (6α-hydroxylating). Enzyme Commission Number: EC 1.14.13.184. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0783; protopanaxadiol 6-hydroxylase; EC 1.14.13.184; protopanaxatriol synthase; P6H; CYP716A53v2; protopanaxadiol,NADPH:O2 oxidoreductase (6α-hydroxylating). Cat No: EXWM-0783. |  |
| 20(R)-Protopanaxadiol | 20(R)-Protopanaxadiol. Group: Biochemicals. Alternative Names: Protopanaxadiol. Grades: Plant Grade. CAS No. 7755-1-3. Pack Sizes: 20mg. Molecular Formula: C30H52O3, Molecular Weight: 460.732. US Biological Life Sciences. | Worldwide |
| (20S)-Protopanaxadiol | (20S)-Protopanaxadiol is used in the treatment of cerebral ischemic injury and the reversal of oxidative stress. A novel class of AMP-activated protein kinase (AMPK) inhibitors affecting glucose and lipid metabolism. Group: Biochemicals. Grades: Highly Purified. CAS No. 30636-90-9. Pack Sizes: 5mg, 50 mg. Molecular Formula: C30H52O3. US Biological Life Sciences. | Worldwide |
| 20(S)-Protopanaxadiol | 20(S)-Protopanaxadiol. Group: Biochemicals. Alternative Names: Protopanaxadiol. Grades: Plant Grade. CAS No. 30636-90-9. Pack Sizes: 20mg. Molecular Formula: C30H52O3, Molecular Weight: 460.732. US Biological Life Sciences. | Worldwide |
| 20-O-multi-glycoside ginsenosidase | The 20-O-multi-glycoside ginsenosidase catalyses the hydrolysis of the 20-O-α-(1?6)-glycosidic bond and the 20-O-β-(1?6)-glycosidic bond of protopanaxadiol-type ginsenosides. The enzyme usually leaves a single glucosyl residue attached at position 20, although it can cleave the remaining glucosyl residue with a lower efficiency. Starting with a ginsenoside that is glycosylated at positions 3 and 20, such as ginsenosides Rb1, Rb2, Rb3 and Rc, the most common product is ginsenoside Rd, with a low amount of ginsenoside Rg3 also formed. Group: Enzymes. Synonyms: ginsenosidase type II (erroneous). Enzyme Commission Number: EC 3.2.1.195. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3879; 20-O-multi-glycoside ginsenosidase; EC 3.2.1.195; ginsenosidase type II (erroneous). Cat No: EXWM-3879. | |
| 5,6-dehydrogensenoside Rd | 5,6-dehydrogensenoside Rd, a triterpenoid reference standard, is a protopanaxadiol isolated from ginsenosides. Protopanaxadiol has been studied to have broad physiological activities, especially the antitumor biological activity. Synonyms: (3beta,12beta)-20-(beta-d-glucopyranosyloxy)-12-hydroxydammara-5,24-dien-3-yl 2-o-beta-d-glucopyranosyl-beta-d-glucopyranoside. Grades: > 98%. CAS No. 1268459-68-2. Molecular formula: C48H80O18. Mole weight: 945.15. |  |
| dammarenediol 12-hydroxylase | A heme-thiolate protein (P-450). Involved in the biosynthetic pathway of ginsenosides. Isolated from ginseng (Panax ginseng). Group: Enzymes. Synonyms: protopanaxadiol synthase; CYP716A47; dammarenediol-II,NADPH:O2 oxidoreductase (12β-hydroxylating). Enzyme Commission Number: EC 1.14.13.183. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0782; dammarenediol 12-hydroxylase; EC 1.14.13.183; protopanaxadiol synthase; CYP716A47; dammarenediol-II,NADPH:O2 oxidoreductase (12β-hydroxylating). Cat No: EXWM-0782. | |
| ginsenosidase type I | Ginsenosidase type I is slightly activated by Mg2+ or Ca2+. The enzyme hydrolyses the 3-O-β-D-(1?2)-glucosidic bond, the 3-O-β-D-glucopyranosyl bond and the 20-O-β-D-(1?6)-glycosidic bond of protopanaxadiol-type ginsenosides. It usually leaves a single glucosyl residue attached at position 20 and one or no glucosyl residues at position 3. Starting with a ginsenoside that is glycosylated at both positions (e.g. ginsenoside Rb1, Rb2, Rb3, Rc or Rd), the most common products are ginsenoside F2 and ginsenoside C-K, with low amounts of ginsenoside Rh2. Group: Enzymes. Enzyme Commission Number: EC 3.2.1.193. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3877; ginsenosidase type I; EC 3.2.1.193. Cat No: EXWM-3877. | |
| ginsenosidase type III | Ginsenosidase type III catalyses the sequential hydrolysis of the 3-O-β-D-(1?2)-glucopyranosyl bond followed by hydrolysis of the 3-O-β-D-glucopyranosyl bond of protopanaxadiol ginsenosides. When acting for example on ginsenoside Rb1 the enzyme first generates ginsenoside XVII, and subsequently ginsenoside LXXV. Group: Enzymes. Enzyme Commission Number: EC 3.2.1.191. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3875; ginsenosidase type III; EC 3.2.1.191. Cat No: EXWM-3875. | |
| Ginsenoside CK | Ginsenoside compound K (C-K) is a metabolite of the protopanaxadiol-type saponins of Panax ginseng C.A. Meyer (Araliaceae), has long been used to treat against the development of cancer, inflammation, allergies, and diabetes; C-K acts as a unique HUVEC migration inhibitor by regulating MMP expression, as well as the activity of SPHK1 and its related sphingolipid metabolites. [1]Ginsenoside compound K, the intestinal metabolite of ginseng saponin, has various chemopreventive and chemotherapeutic activities, including anti-tumor activity; C-K suppresses the activation of the NF-κB pathway, may become a potential cytotoxic drug in the prevention and treatment of hepatocellular carcinoma( HCC).[2]Ginsenoside compound K shows significant anti-proliferative effects and pro-apoptotic effects in HCT-116 and SW-480 cells at concentrations of 30-50 uM, suggests that C-K could be potentially effective anti-colorectal cancer agent.[3]Ginsenoside CK has anti-cancer effect on NPC cells, C-K-induced apoptosis of HK-1 cells was mediated by the mitochondrial pathway and could significantly inhibit tumor growth in vivo.[4]. Group: Biochemicals. Alternative Names: (3 β,12 β)-3,12-Dihydroxydammar-24-en-2. Grades: Highly Purified. CAS No. 39262-14-1. Pack Sizes: 10mg, 20mg, 50mg, 100mg. Molecular Formula: C??H??O?, Molecular Weight: 622.87. US Biological Life Sciences. | Worldwide |
| Ginsenoside Ra3 | Ginsenoside Ra3 is isolated from the root of Panax ginseng. Protopanaxadiol- and protopanaxatriol-type ginsenosides are the major biologically active components of P. ginseng that contribute to its diverse pharmacological effects on the central nervous system, cardiovascular system, endocrine secretion, immune-modulation, metabolism, stress, aging, and cancer. Synonyms: β-D-Glucopyranoside, (3β,?12β)?-12-hydroxy-20-[(O-β-D-xylopyranosyl-(1?3)?-O-β-D-glucopyranosyl-(1?6)?-β-D-glucopyranosyl)?oxy]?dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-; (3β,12β)-12-Hydroxy-20-[(O-β-D-xylopyranosyl-(1?3)-O-β-D-glucopyranosyl-(1?6)-β-D-glucopyranosyl)oxy]dammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside; Dammarane, β-D-glucopyranoside deriv. Grades: > 98%. CAS No. 90985-77-6. Molecular formula: C59H100O27. Mole weight: 1241.41. | |
| Pyxinol | Pyxinol is the main metabolite of 20S-protopanaxadiol in the human liver. Synonyms: Pixinol; Dammarane-3β,12β,25-triol, 20,24-epoxy-, (20R,24S)- (8CI); (3β,12β,20R,24S)-20,24-Epoxydammarane-3,12,25-triol. CAS No. 25330-18-1. Molecular formula: C30H52O4. Mole weight: 476.73. | |
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