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Pseudaminic acid is an indispensable compound in the biomedical sector assuming a pivotal involvement in the synthesis of pseudaminic acid capsules, designated for studying bacterial infections resulting from pathogens that express pseudaminic acid-binding proteins. Synonyms: 5,7-Bis(acetylamino)-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-2-nonulopyranosonic acid. Molecular formula: C13H22N2O8. Mole weight: 334.32.
pseudaminic acid cytidylyltransferase
Mg2+ is required for activity. Group: Enzymes. Synonyms: PseF. Enzyme Commission Number: EC 2.7.7.81. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3294; pseudaminic acid cytidylyltransferase; EC 2.7.7.81; PseF. Cat No: EXWM-3294.
pseudaminic acid synthase
The enzyme requires a divalent metal ion, the highest activity values are observed in the presence of Mn2+ and Co2+ (10 mM). Group: Enzymes. Synonyms: PseI; NeuB3. Enzyme Commission Number: EC 2.5.1.97. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2836; pseudaminic acid synthase; EC 2.5.1.97; PseI; NeuB3. Cat No: EXWM-2836.
CMP-Pseudaminic acid
CMP-Pseudaminic acid is a compound of immense value, serving as a fundamental building block for the bioresearch and development of pseudaminic acid, a vital constituent of bacterial glycosylated proteins. By impeding enzymatic development, CMP-Pseudaminic acid reveals promising prospects for research of bacterial infections triggered by notorious pathogens like Campylobacter jejuni and Helicobacter pylori. Synonyms: CMP-Pse. Molecular formula: C22H32N5O15P. Mole weight: 637.49.
The enzyme is involved in biosynthesis of pseudaminic acid. Group: Enzymes. Synonyms: PseG; UDP-6-deoxy-AltdiNAc hydrolase; Cj1312; UDP-2,4-bis(acetamido)-2,4,6-trideoxy-β-L-altropyranose hydrolase. Enzyme Commission Number: EC 3.6.1.57. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4629; UDP-2,4-diacetamido-2,4,6-trideoxy-β-L-altropyranose hydrolase; EC 3.6.1.57; PseG; UDP-6-deoxy-AltdiNAc hydrolase; Cj1312; UDP-2,4-bis(acetamido)-2,4,6-trideoxy-β-L-altropyranose hydrolase. Cat No: EXWM-4629.
Isolated from Helicobacter pylori. The enzyme is involved in the biosynthesis of pseudaminic acid. Group: Enzymes. Synonyms: PseH. Enzyme Commission Number: EC 2.3.1.202. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2147; UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine N-acetyltransferase; EC 2.3.1.202; PseH. Cat No: EXWM-2147.
A pyridoxal-phosphate protein. The enzyme is involved in biosynthesis of pseudaminic acid. Group: Enzymes. Synonyms: PseC. Enzyme Commission Number: EC 2.6.1.92. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2933; UDP-4-amino-4,6-dideoxy-N-acetyl-β-L-altrosamine transaminase; EC 2.6.1.92; PseC. Cat No: EXWM-2933.
Contains NADP+ as a cofactor. This is the first enzyme in the biosynthetic pathway of pseudaminic acid, a sialic-acid-like sugar that is unique to bacteria and is used by Helicobacter pylori to modify its flagellin. This enzyme plays a critical role in H. pylori's pathogenesis, being involved in the synthesis of both functional flagella and lipopolysaccharides. It is completely inhibited by UDP-α-D-galactose. The reaction results in the chirality of the C-5 atom being inverted. It is thought that Lys-133 acts sequentially as a catalytic acid, protonating the C-6 hydroxy group and as a catalytic base, abstracting the C-5 proton, resulting in the elimination of water. This enzyme belongs to the short-chain dehydrogenase/reductase family of enzymes. Group: Enzymes. Synonyms: FlaA1; UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase; PseB; UDP-N-acetylglucos. Enzyme Commission Number: EC 4.2.1.115. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4955; UDP-N-acetylglucosamine 4,6-dehydratase (configuration-inverting); EC 4.2.1.115; FlaA1; UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase; PseB; UDP-N-acetylglucosamine hydro-lyase (inverting; UDP-2-acetamido-2,6-dideoxy-β-L-arabino-hex-4-ulose-forming). Cat No: EXWM-4955.
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