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| Product | Description | |
|---|---|---|
| Pseudouridine | An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called ? synthases, which post-transcriptionally isomerize specific uridine residues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes. Group: Biochemicals. Alternative Names: 5- β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione; 5-( β-D-Ribofuranosyl)uracil; 5-Ribosyluracil; NSC 162405; Pseudouridine C; β-D-Pseudouridine; Pseudouridine; ?-Uridine. Grades: Highly Purified. CAS No. 1445-07-4. Pack Sizes: 25mg, 50mg, 100mg. Molecular Formula: C9H12N2O6, Molecular Weight: 244.2. US Biological Life Sciences. |  Worldwide |
| Pseudouridine | Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 1445-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113061. |  |
| PseudoUridine 5'-monophosphate | A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Synonyms: Pseudouridylic acid; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol; pseudouridine 5'-phosphate; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione; 5-b-D-Ribofuranosyluracil 5'-phosphate; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate. Grades: ≥95%. CAS No. 1157-60-4. Molecular formula: C9H13N2O9P. Mole weight: 324.18. |  |
| PseudoUridine 5'-monophosphate Sodium salt | A metabolic process has been acknowledged for pseudoUridine, and it involves the pseudoUridine phosphorylation to generate pseudoUridine 5?-monophosphate (ΨMP) catalyzed by the enzyme pseudoUridine kinase and thereafter the C-C glycosidic bond cleavage to give uracil and ribose 5-phosphate which mediated by the pseudoUridine 5?-monophosphate glycosidase. Synonyms: Pseudouridylic acid sodium salt; (1S)-1,4-anhydro-1-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-5-O-phosphono-D-ribitol sodium salt; pseudouridine 5'-phosphate sodium salt; 5-(5-O-phosphono-beta-D-ribofuranosyl)pyrimidine-2,4(1H,3H)-dione sodium salt; 5-b-D-Ribofuranosyluracil 5'-phosphate sodium salt; Uracil, 5-b-D-ribofuranosyl-, 5'-phosphate, sodium salt. Molecular formula: C9H13N2O9P.xNa. Mole weight: 324.18 (free acid). | |
| pseudouridine 5'-phosphatase | Requires Mg2+ for activity. Group: Enzymes. Synonyms: pseudouridine 5'-monophosphatase; 5'-PsiMPase; HDHD1. Enzyme Commission Number: EC 3.1.3.96. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3703; pseudouridine 5'-phosphatase; EC 3.1.3.96; pseudouridine 5'-monophosphatase; 5'-PsiMPase; HDHD1. Cat No: EXWM-3703. |  |
| Pseudouridine-5'-Triphosphate | | |
| PseudoUridine 5'-Triphosphate | PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock. Synonyms: Pseudo-UTP; 5-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-2, 4 (1H, 3H) pyrimidinedione; 5-β-D-Ribofuranosyluracil 5'-Triphosphate; Pseudouridine Triphosphate. Grades: ≥95% by HPLC. CAS No. 1175-34-4. Molecular formula: C9H15N2O15P3. Mole weight: 484.14. | |
| PseudoUridine 5'-Triphosphate Lithium | | |
| Pseudouridine 5'-triphosphate lithium salt | PseudoUridine 5'-Triphosphate is a modified nucleoside used for the polymerase-mediated synthesis of RNA molecules. The sodium salt form PseudoUridine 5'-Triphosphate Sodium (B2706-358098) is in stock. Synonyms: ((2R,3S,4R,5S)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl triphosphate tetralithium salt. Grades: ≥95%. Molecular formula: C9H11Li4N2O15P3. Mole weight: 507.87. | |
| PseudoUridine 5'-Triphosphate Sodium | PseudoUridine 5'-Triphosphate Sodium is a compound, finding extensive employment in the exploration of RNA modifications and nucleotide analogs. Synonyms: Sodium ((2R,3S,4R,5S)-5-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate; 5-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-β -D-ribofuranosyl]-2, 4 (1H, 3H) pyrimidinedione Sodium salt; Pseudo UTP Sodium salt; 5-Ribosyl Uraci Sodium salt; 5-β-D-Ribofuranosyluracil 5'-Triphosphate Sodium Salt; Pseudouridine Triphosphate Sodium Salt; PseudoUridine 5'-Triphosphate; Pseudo UTP; Pseudo-UTP. Grades: ≥95%. Molecular formula: C9H15N2O15P3.xNa. Mole weight: 484.14 (free acid). | |
| Pseudouridine-5'-triphosphate trisodium salt | Pseudouridine-5'-triphosphate trisodium salt, an indispensable compound in the biomedical realm, serves as a synthetically modified nucleoside triphosphate integral to RNA studies. Exhibiting remarkable efficacy in combatting diverse human afflictions - anti-tumor, antiviral, and anticancer among many others - this compound has also been shown to mediate transcriptional regulation in bacterial populations and has been investigated in the context of metabolic syndromes like obesity. Synonyms: Pseudo-UTP trisodium salt; 5-Ribosyl Uracil trisodium salt; sodium ((2R,3S,4R,5S)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate; 5'-triphospho-pseudouridine sodium salt; Pseudouridine 5'-triphosphate (trisodium). Grades: ≥97% by AX-HPLC. Molecular formula: C9H12N2Na3O15P3. Mole weight: 550.09. | |
| Pseudouridine-5'-triphosphate Trisodium Salt, 100mM (Liquid) (Pseudo-UTP) | Pseudouridine-5'-triphosphate trisodium salt, 100mM aqueous solution.Uridine analog as ribonucleate nucleotidyltransferase substrate. Group: Biochemicals. Alternative Names: Pseudo-UTP. Grades: Highly Purified. CAS No. 1175-34-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C9H12N2O15P3Na3, Molecular Weight: 550.09. US Biological Life Sciences. | Worldwide |
| PseudoUridine B | Pseudouridine B is an isomer of Pseudouridine from wheat bran. Synonyms: α-pseudouridine; 5-α-D-ribofuranosyl-2,?4(1H,?3H)?-Pyrimidinedione; Alpha-Pseudouridine; Uracil, 5-a-D-ribofuranosyl-. Grades: 99%. CAS No. 10017-66-0. Molecular formula: C9H12N2O6. Mole weight: 244.2. | |
| pseudouridine kinase | This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:pseudouridine 5'-phosphotransferase. This enzyme is also called pseudouridine kinase (phosphorylating). This enzyme participates in pyrimidine metabolism. Group: Enzymes. Synonyms: pseudouridine kinase (phosphorylating). Enzyme Commission Number: EC 2.7.1.83. CAS No. 62213-40-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3113; pseudouridine kinase; EC 2.7.1.83; 62213-40-5; pseudouridine kinase (phosphorylating). Cat No: EXWM-3113. | |
| 16S rRNA pseudouridine516 synthase | The enzyme is specific for uridine516 in 16S rRNA. In vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins. Group: Enzymes. Synonyms: 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Enzyme Commission Number: EC 5.4.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5558; 16S rRNA pseudouridine516 synthase; EC 5.4.99.19; 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Cat No: EXWM-5558. | |
| 1-MethylpseudoUridine | N1-methyl-pseudoUridine (1-Methylpseudouridine), a methylpseudoUridine, outperforms 5 mC and 5 mC/N1-methyl-pseudoUridine in translation. N1-methyl-pseudoUridine in mRNA enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density. Synonyms: N1-Methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 1-methyl-5-b-D-ribofuranosyl-; (-)-1-Methyl-5-(β-D-ribofuranosyl)-2,4(1H,3H)-pyrimidinedione; Antibiotic U-50228; U-50228; 1-N-Me-pseudouridine; (1S)-1,4-anhydro-1-(1-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-D-ribitol; Uracil, 1-methyl-5-b-D-ribofuranosyl-. Grades: ≥95%. CAS No. 13860-38-3. Molecular formula: C10H14N2O6. Mole weight: 258.23. | |
| 21S rRNA pseudouridine2819 synthase | The enzyme specifically acts on uridine2819 in 21S rRNA. Group: Enzymes. Synonyms: Pus5p. Enzyme Commission Number: EC 5.4.99.43. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5585; 21S rRNA pseudouridine2819 synthase; EC 5.4.99.43; Pus5p. Cat No: EXWM-5585. | |
| 23S rRNA pseudouridine1911/1915/1917 synthase | Pseudouridine synthase RluD converts uridines at positions 1911, 1915, and 1917 of 23S rRNA to pseudouridines. These nucleotides are located in the functionally important helix-loop 69 of 23S rRNA. Group: Enzymes. Synonyms: RluD; pseudouridine synthase RluD. Enzyme Commission Number: EC 5.4.99.23. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5563; 23S rRNA pseudouridine1911/1915/1917 synthase; EC 5.4.99.23; RluD; pseudouridine synthase RluD. Cat No: EXWM-5563. | |
| 23S rRNA (pseudouridine1915-N3)-methyltransferase | YbeA does not methylate uridine at position 1915. Group: Enzymes. Synonyms: YbeA; RlmH; pseudouridine methyltransferase; m3ψ methyltransferase; ψ1915-specific methyltransferase; rRNA large subunit methyltransferase H. Enzyme Commission Number: EC 2.1.1.177. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1775; 23S rRNA (pseudouridine1915-N3)-methyltransferase; EC 2.1.1.177; YbeA; RlmH; pseudouridine methyltransferase; m3ψ methyltransferase; ψ1915-specific methyltransferase; rRNA large subunit methyltransferase H. Cat No: EXWM-1775. | |
| 23S rRNA pseudouridine2457 synthase | The enzyme modifies uridine2457 in a stem of 23S RNA in Escherichia coli. Group: Enzymes. Synonyms: RluE; YmfC. Enzyme Commission Number: EC 5.4.99.20. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5560; 23S rRNA pseudouridine2457 synthase; EC 5.4.99.20; RluE; YmfC. Cat No: EXWM-5560. | |
| 23S rRNA pseudouridine2604 synthase | The enzyme is not completely specific for uridine2604 and can, to a small extent, also react with uridine2605. Group: Enzymes. Synonyms: RluF; YjbC. Enzyme Commission Number: EC 5.4.99.21. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5561; 23S rRNA pseudouridine2604 synthase; EC 5.4.99.21; RluF; YjbC. Cat No: EXWM-5561. | |
| 23S rRNA pseudouridine2605 synthase | Pseudouridine synthase RluB converts uridine2605 of 23S rRNA to pseudouridine. Group: Enzymes. Synonyms: RluB; YciL. Enzyme Commission Number: EC 5.4.99.22. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5562; 23S rRNA pseudouridine2605 synthase; EC 5.4.99.22; RluB; YciL. Cat No: EXWM-5562. | |
| 23S rRNA pseudouridine746 synthase | RluA is the sole protein responsible for the in vivo formation of 23S RNA pseudouridine746. The dual-specificity enzyme also catalyses the formation of uridine32 in tRNA. cf. EC 5.4.99.28 (tRNA pseudouridine32 synthase). Group: Enzymes. Synonyms: RluA (ambiguous); 23S RNA PSI746 synthase; 23S rRNA pseudouridine synthase; pseudouridine synthase RluA (ambiguous). Enzyme Commission Number: EC 5.4.99.29. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5569; 23S rRNA pseudouridine746 synthase; EC 5.4.99.29; RluA (ambiguous); 23S RNA PSI746 synthase; 23S rRNA pseudouridine synthase; pseudouridine synthase RluA (ambiguous). Cat No: EXWM-5569. | |
| 23S rRNA pseudouridine955/2504/2580 synthase | The enzyme converts uridines at position 955, 2504 and 2580 of 23S rRNA to pseudouridines. Group: Enzymes. Synonyms: RluC; pseudouridine synthase RluC. Enzyme Commission Number: EC 5.4.99.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5564; 23S rRNA pseudouridine955/2504/2580 synthase; EC 5.4.99.24; RluC; pseudouridine synthase RluC. Cat No: EXWM-5564. | |
| 2'-Deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite | 2'-Deoxy-5'-O-DMT-pseudouridine 3'-CE phosphoramidite. Group: Biochemicals. Grades: Highly Purified. CAS No. 289712-98-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C39H47N4O8P. US Biological Life Sciences. | Worldwide |
| 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-Me-PseudoUridine-CE-Phosphoramidite is a phosphoramidite derivative used in the synthesis of modified oligonucleotides for biomedical research. It enables the incorporation of 2'-O-methyl-pseudouridine modifications into RNA sequences, enhancing stability and specific RNA-protein interactions. Synonyms: 2'-O-Methyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; pseudoUridine (with 5'-DMT, 3'-phosphoramidite, and 2'-OMe); 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-methyl-β-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione. CAS No. 199737-09-2. Molecular formula: C40H49N4O9P. Mole weight: 760.81. | |
| 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine | 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine is an indispensable compound in contemporary biomedical research, exhibiting noteworthy potential in the realm of antiviral drug development. It manifests remarkable inhibitory prowess against viral polymerase enzymes, warranting its extensive utilization in this field. Furthermore, its pivotal involvement in unraveling RNA's intricate structural dynamics and functional attributes establishes its paramount importance. CAS No. 875302-41-3. Molecular formula: C37H46N2O8Si. Mole weight: 674.86. | |
| 5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | It is a modified ribonucleoside analogue suitable for incorporation into small interfering RNA (siRNA) to enhance RNA stability in biological applications such as gene silencing. Synonyms: 5'-Dimethoxytrityl-1-methyl-pseudouridine, 2'-O-TBDMS-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; 5-[5-O-[bis(4-methoxyphenyl)?phenylmethyl]?-3-O-[[bis(1-methylethyl)?amino]?(2-cyanoethoxy)?phosphino]?-2-O-[(1,?1-dimethylethyl)?dimethylsilyl]?-β-D-ribofuranosyl]?-1-methyl-2,?4(1H,?3H)?-pyrimidinedione. Grades: ≥98%. CAS No. 875302-45-7. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-2'-O-TBDMS-PseudoUridine | 5'-DMT-2'-O-TBDMS-PseudoUridine, a modified nucleoside of immense significance, serves as a fundamental constituent in the synthetic construction of altered RNA molecules. Its pseudouridine backbone modification and safeguarded functional groups contribute significantly to its pivotal role as an indispensable instrument in the advancement of RNA-centric therapeutics. This distinctive compound manifests immense potential in the realm of gene therapy and drug delivery systems, exemplifying its ability to target a wide array of ailments such as cancer, viral infections, and genetic anomalies. Synonyms: 5- ( (2S, 3R, 4R, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3- ( (tert-butyldimethylsilyl)oxy)-4-hydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione. CAS No. 144429-56-1. Molecular formula: C36H44N2O8Si. Mole weight: 660.83. | |
| 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-2'-O-TBDMS-PseudoUridine-CE-Phosphoramidite is a valuable compound primarily employed for the research and development of RNA molecules required for diagnostic purposes or therapeutic interventions. This compound plays a crucial role in the development of drugs targeting specific diseases and disorders, such as cancers or viral infections. It facilitates efficient nucleotide incorporation and ensures accurate development of RNA sequences. Synonyms: 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-pseudoUridine 3'-CE phosphoramidite; PseudoUridine-CE Phosphoramidite; Pseudouridine CEP; 5-[5-O-[Bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-O-[(1,1-dimethylethyl)dimethylsilyl]-beta-D-ribofuranosyl]-2,4(1H,3H)-pyrimidinedione. Grades: ≥95%. CAS No. 163496-23-9. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine, an essential compound in the field of biomedical research, holds immense significance for studying RNA modifications. Its role as a powerful tool in unraveling the impact of modified nucleosides on RNA structure and function is undeniable. Furthermore, its potential therapeutic implications in combating RNA dysregulation-associated ailments, such as cancer and neurodegenerative disorders, make it a promising avenue worth exploring. Synonyms: 3'-O-tert-butyldimethylsilyl-5'-O-DMT-N1-methylpseudoUridine; 5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyl-N1-methylpseudouridine; 2,4(1H,3H)-Pyrimidinedione, 5-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[(1,1-dimethylethyl)dimethylsilyl]-β-D-ribofuranosyl]-1-methyl-; 5'-O-(4,4'-dimethoxitrityl)-3'-O-(tert-butyldimethylsilyl)-1-N-methylpseudouridine; 5-[(2S,3S,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[tert-butyl(dimethyl)silyl]oxy-3-hydroxyoxolan-2-yl]-1-methylpyrimidine-2,4-dione. Grades: ≥95%. CAS No. 875302-43-5. Molecular formula: C37H46N2O8Si. Mole weight: 674.86. | |
| 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite, a highly valued compound within the biomedicine sector, plays a pivotal role in the synthetic production of altered nucleic acids. Primarily employed as a fundamental unit during oligonucleotide formation, it showcases tremendous potential in advancing RNA-based therapeutic interventions. Through its exceptional capability, this product empowers precise and effective nucleoside modification, enabling targeted remedies for an array of prevalent ailments including viral afflictions and hereditary anomalies. Synonyms: (2S, 3S, 4R, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-4- ( (tert-butyldimethylsilyl)oxy)-2- (1-methyl-2, 4-dioxo-1, 2, 3, 4-tetrahydropyrimidin-5-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite; 875302-47-9. CAS No. 875302-47-9. Molecular formula: C46H63N4O9PSi. Mole weight: 875.07. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine | 5'-DMT-3'-O-TBDMS-PseudoUridine, an essential ingredient in the advancement of nucleic acid therapeutics, demonstrates a pivotal function in the alteration of RNA molecules. This alteration facilitates precise ailment targeting and therapy for a diverse range of afflictions such as viral infections and genetic disorders. CAS No. 144429-58-3. Molecular formula: C36H44N2O8Si. Mole weight: 660.83. | |
| 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite | 5'-DMT-3'-O-TBDMS-PseudoUridine-CE-Phosphoramidite, an indispensable compound in the thriving biomedical sector, serves as a pivotal component for oligonucleotide synthesis. This ground-breaking technique unlocks unparalleled potential to combat a myriad of afflictions encompassing cancer, viral infections, and genetic aberrations. Molecular formula: C45H61N4O9PSi. Mole weight: 861.05. | |
| 5'-DMT-PseudoUridine | 5'-DMT-PseudoUridine, a pivotal compound within the field of biomedicine, plays a profound and indispensable part in the therapeutic approach towards various diseases, enabling the alteration of RNA molecules. Its unparalleled characteristics not only bolster RNA stability but also foster heightened protein synthesis and regulate cellular mechanisms. Synonyms: SCHEMBL1750218; 144429-55-0; 5- ( (2S, 3R, 4S, 5R)-5- ( (Bis (4-methoxyphenyl) (phenyl)methoxy)methyl)-3, 4-dihydroxytetrahydrofuran-2-yl)pyrimidine-2, 4 (1H, 3H)-dione. CAS No. 144429-55-0. Molecular formula: C30H30N2O8. Mole weight: 546.57. | |
| β-Pseudouridine-13C, 15N2 | β-Pseudouridine-13C, 15N2. Group: Biochemicals. Alternative Names: 5- β-D-Ribofuranosyl-2,4(1H,3H)-Pyrimidinedione-13C, 15N2; 5-( β-D-Ribofuranosyl)uracil-13C, 15N2; 5-Ribosyluracil-13C, 15N2; NSC 162405-13C, 15N2; Pseudouridine C; β-D-Pseudouridine-13C, 15N2; Pseudouridine-13C, 15N2; ?-Uridine-13C, 15N2. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C9H1215N2O6, Molecular Weight: 246.19. US Biological Life Sciences. | Worldwide |
| mitochondrial tRNA pseudouridine27/28 synthase | The mitochondrial enzyme Pus2p is specific for position 27 or 28 in mitochondrial tRNA. Group: Enzymes. Synonyms: Pus2; Pus2p; RNA:pseudouridine synthases 2. Enzyme Commission Number: EC 5.4.99.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5586; mitochondrial tRNA pseudouridine27/28 synthase; EC 5.4.99.44; Pus2; Pus2p; RNA:pseudouridine synthases 2. Cat No: EXWM-5586. | |
| N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)]propylpseudouridine | N1-Methyl-N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)]propylpseudouridine is a modified pseudouridine derivative, undergoing N1 methylation and N3-[(2S)-2-(t-butoxycarbonyl)amino-3-(t-butoxycarbonyl)]propylation, exhibiting immense promise within targeted drug delivery systems. Synonyms: 1(2H)-Pyrimidinebutanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-3,6-dihydro-3-methyl-2,6-dioxo-5-β-D-ribofuranosyl-, 1,1-dimethylethyl ester, (βS)-. Grades: ≥95%. CAS No. 1613530-24-7. Molecular formula: C23H37N3O10. Mole weight: 515.55. | |
| N1-Methyl-Pseudouridine | N1-Methyl-Pseudouridine. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1-methylpyrimidine-2,4(1H,3H)-dione. CAS No. 13860-38-3. Molecular Formula: C10H14N2O6. Mole Weight: 258.23. Catalog: APB13860383. |  |
| N1-(N,N-Dimethylaminocarbonyl)-pseudouridine | N1-(N,N-Dimethylaminocarbonyl)-pseudouridine is a remarkable biomedical compound with exceptional antiviral properties, aiding in studying viral infections. Synonyms: HY-152325. Grades: ≥95%. Molecular formula: C12H17N3O7. Mole weight: 315.28. | |
| N1-Propargylpseudouridine | N1-Propargylpseudouridine, a captivating compound extensively employed in biomedical investigation, showcases immense potential as a remedial entity for an array of ailments encompassing cancer, viral infections, and neurodegenerative disorders. Functioning as an agent that modifies RNA, this compound effectively targets intricate cellular mechanisms implicated in the progression of diseases. By virtue of its extraordinary chemical constitution and pharmacological attributes, N1-Propargylpseudouridine exhibits exceptional promise in propelling the frontiers of biomedical interventions. Synonyms: 1-propargyl-pseudouridine; 5-[(2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1-prop-2-ynylpyrimidine-2,4-dione. Grades: ≥95%. CAS No. 1464021-70-2. Molecular formula: C12H14N2O6. Mole weight: 282.25. | |
| rRNA small subunit pseudouridine methyltransferase Nep1 | This enzyme, which occurs in both prokaryotes and eukaryotes, recognizes specific pseudouridine residues (ψ) in small subunits of ribosomal RNA based on the local RNA structure. It recognizes ψ914 in 16S rRNA from the archaeon Methanocaldococcus jannaschii, ψ1191 in yeast 18S rRNA, and ψ1248 in human 18S rRNA. Group: Enzymes. Synonyms: Nep1; nucleolar essential protein 1. Enzyme Commission Number: EC 2.1.1.260. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1865; rRNA small subunit pseudouridine methyltransferase Nep1; EC 2.1.1.260; Nep1; nucleolar essential protein 1. Cat No: EXWM-1865. | |
| tRNA pseudouridine13 synthase | Pseudouridine synthase TruD from Escherichia coli specifically acts on uridine13 in tRNA. The Pus7 protein from Saccharomyces cerevisiae is a multisite-multisubstrate pseudouridine synthase that is able to modify uridine13 in several yeast tRNAs, uridine35 in the pre-tRNATyr, uridine35 in U2 small nuclear RNA, and uridine50 in 5S rRNA. Group: Enzymes. Synonyms: TruD; YgbO; tRNA PSI13 synthase; RNA:PSI-synthase Pus7p; Pus7p; RNA:pseudouridine-synthase Pus7p; Pus7 protein. Enzyme Commission Number: EC 5.4.99.27. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5567; tRNA pseudouridine13 synthase; EC 5.4.99.27; 430429-15-5; TruD; YgbO; tRNA PSI13 synthase; RNA:PSI-synthase Pus7p; Pus7p; RNA:pseudouridine-synthase Pus7p; Pus7 protein. Cat No: EXWM-5567. | |
| tRNA pseudouridine31 synthase | The enzyme specifically acts on uridine31 in tRNA. Group: Enzymes. Synonyms: Pus6p. Enzyme Commission Number: EC 5.4.99.42. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5584; tRNA pseudouridine31 synthase; EC 5.4.99.42; Pus6p. Cat No: EXWM-5584. | |
| tRNA pseudouridine32 synthase | The dual-specificity enzyme from Escherichia coli also catalyses the formation of pseudouridine746 in 23S rRNA. cf. EC 5.4.99.29 (23S rRNA pseudouridine746 synthase). Group: Enzymes. Synonyms: RluA (ambiguous); pseudouridine synthase RluA (ambiguous); Pus9p; Rib2/Pus8p. Enzyme Commission Number: EC 5.4.99.28. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5568; tRNA pseudouridine32 synthase; EC 5.4.99.28; 430429-15-5; RluA (ambiguous); pseudouridine synthase RluA (ambiguous); Pus9p; Rib2/Pus8p. Cat No: EXWM-5568. | |
| tRNA pseudouridine38/39 synthase | The enzyme from Saccharomyces cerevisiae is active only towards uridine38 and uridine39, and shows no activity with uridine40 (cf. EC 5.4.99.12, tRNA pseudouridine38-40 synthase). In vitro the enzyme from mouse is active on uridine39 and very slightly on uridine38 (human tRNALeu). Group: Enzymes. Synonyms: Deg1; Pus3p; pseudouridine synthase 3. Enzyme Commission Number: EC 5.4.99.45. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5587; tRNA pseudouridine38/39 synthase; EC 5.4.99.45; Deg1; Pus3p; pseudouridine synthase 3. Cat No: EXWM-5587. | |
| tRNA pseudouridine38-40 synthase | The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs are isomerized to pseudouridine. TruA specifically modifies uridines at positions 38, 39, and/or 40 in the anticodon stem loop of tRNAs with highly divergent sequences and structures. Group: Enzymes. Synonyms: TruA; tRNA pseudouridine synthase I; PSUI; hisT (gene name). Enzyme Commission Number: EC 5.4.99.12. CAS No. 61506-89-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5551; tRNA pseudouridine38-40 synthase; EC 5.4.99.12; 61506-89-6; TruA; tRNA pseudouridine synthase I; PSUI; hisT (gene name). Cat No: EXWM-5551. | |
| tRNA (pseudouridine54-N1)-methyltransferase | While this archaeal enzyme is specific for the 54 position and does not methylate pseudouridine at position 55, the presence of pseudouridine at position 55 is necessary for the efficient methylation of pseudouridine at position 54. Group: Enzymes. Synonyms: TrmY; m1ψ methyltransferase. Enzyme Commission Number: EC 2.1.1.257. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1861; tRNA (pseudouridine54-N1)-methyltransferase; EC 2.1.1.257; TrmY; m1ψ methyltransferase. Cat No: EXWM-1861. | |
| tRNA pseudouridine55 synthase | Pseudouridine synthase TruB from Escherichia coli specifically modifies uridine55 in tRNA molecules. The bifunctional archaeal enzyme also catalyses the pseudouridylation of uridine54. It is not known whether the enzyme from Escherichia coli can also act on position 54 in vitro, since this position is occupied in Escherichia coli tRNAs by thymine. Group: Enzymes. Synonyms: TruB; aCbf5; Pus4; YNL292w (gene name); ψ55 tRNA pseudouridine synthase; tRNA:ψ55-synthase; tRNA pseudouridine 55 synthase; tRNA:pseudouridine-55 synthase; ψ55 synthase; tRNA ψ55 synthase; tRNA:ψ55 synthase; tRNA-uridine55 uracil mutase; Pus10; tRNA-uridine54/55 uracil mutase. Enzyme Commission Number: EC 5.4.99.25. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5565; tRNA pseudouridine55 synthase; EC 5.4.99.25; 430429-15-5; TruB; aCbf5; Pus4; YNL292w (gene name); ψ55 tRNA pseudouridine synthase; tRNA:ψ55-synthase; tRNA pseudouridine 55 synthase; tRNA:pseudouridine-55 synthase; ψ55 synthase; tRNA ψ55 synthase; tRNA:ψ55 synthase; tRNA-uridine55 uracil mutase; Pus10; tRNA-uridine54/55 uracil mutase. Cat No: EXWM-5565. | |
| tRNA pseudouridine65 synthase | TruC specifically modifies uridines at positions 65 in tRNA. Group: Enzymes. Synonyms: TruC; YqcB. Enzyme Commission Number: EC 5.4.99.26. CAS No. 430429-15-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5566; tRNA pseudouridine65 synthase; EC 5.4.99.26; 430429-15-5; TruC; YqcB. Cat No: EXWM-5566. | |
| 1-C-[2,4-Bis(1,1-dimethylethoxy)-5-pyrimidinyl]-5-O-(1-methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-α-D-ribofuranose | 1-C-[2,4-Bis(1,1-dimethylethoxy)-5-pyrimidinyl]-5-O-(1-methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-α-D-ribofuranose is an intermediate in the synthesis of β-Pseudouridine, an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. CAS No. 631920-67-7. Molecular formula: C24H40N2O8. Mole weight: 484.58. | |
| 1-C-[2,4-Bis(1,1-dimethylethoxy)-5-pyrimidinyl]-5-O-(1-methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-α-D-ribofuranose | 1-C-[2,4-Bis(1,1-dimethylethoxy)-5-pyrimidinyl]-5-O-(1-methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-α-D-ribofuranose is an intermediate in the synthesis of β-Pseudouridine (O839607), an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. Group: Biochemicals. Grades: Highly Purified. CAS No. 631920-67-7. Pack Sizes: 10mg, 100mg. Molecular Formula: C24H40N2O8. US Biological Life Sciences. | Worldwide |
| 2, 4-Bis (1, 1-dimethylethoxy) pyrimidine-13C, 15N2 | 2, 4-Bis (1, 1-dimethylethoxy) pyrimidine-13C, 15N2 is an isotope labelled intermediate in the synthesis of β-Pseudouridine (O839607), an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg, 100mg. Molecular Formula: C1113CH2015N2O2. US Biological Life Sciences. | Worldwide |
| 5,6-Dihydro-5-azathymidine | 5,6-Dihydro-5-azathymidine is produced by the strain of Streptomyces platensis var. clarensis (NRRL-8035). It has anti-gram-positive bacteria, negative bacteria and DNA virus activities. The strain also produces pseudouridine and 1-methylpseudouridine. Synonyms: 1-(2-Deoxypentofuranosyl)-4-hydroxy-5-methyl-5,6-dihydro-1,3,5-triazin-2(1H)-one. CAS No. 57350-36-4. Molecular formula: C9H15N3O5. Mole weight: 245.23. | |
| 5-O-(1-Methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-D-ribonic Acid γ-Lactone | 5-O-(1-Methoxy-1-methylethyl)-2,3-O-(1-methylethylidene)-D-ribonic Acid γ-Lactone is an intermediate in the synthesis of β-Pseudouridine, an isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. Synonyms: 5-O-(1-Methoxy-1-Methylethyl)-2,3-O-(1-Methylethylidene)-D-ribonic Acid gamma-Lactone. CAS No. 162635-53-2. Molecular formula: C12H20O6. Mole weight: 260.28. | |
| pseudouridylate synthase | The reaction it readily reversible. While the enzymes from Tetrahymena pyriformis and Agrobacterium tumefaciens produce pseudouridine 5'-phosphate the enzyme from Escherichia coli functions as a pseudouridine-5'-phosphate glycosidase in vivo. Group: Enzymes. Synonyms: pseudouridylic acid synthetase; pseudouridine monophosphate synthetase; 5-ribosyluracil 5-phosphate synthetase; pseudouridylate synthetase; upsilonUMP synthetase; uracil hydro-lyase (adding D-ribose 5-phosphate); YeiN; pseudouridine-5'-phosphate glycosidase. Enzyme Commission Number: EC 4.2.1.70. CAS No. 9023-35-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5056; pseudouridylate synthase; EC 4.2.1.70; 9023-35-2; pseudouridylic acid synthetase; pseudouridine monophosphate synthetase; 5-ribosyluracil 5-phosphate synthetase; pseudouridylate synthetase; upsilonUMP synthetase; uracil hydro-lyase (adding D-ribose 5-phosphate); YeiN; pseudouridine-5'-phosphate glycosidase. Cat No: EXWM-5056. | |
| Pyrrolo-C | Pyrrolo-C is an isomer of uridine found in many classes of RNA except mRNA. Studies shows that β-Pseudouridine could reduce radiation-induced chromosome aberrations in human lymphocytes. Synonyms: 6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one; 6-Methyl-3-(beta-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one. Grades: ≥ 97%. CAS No. 644962-84-5. Molecular formula: C12H15N3O5. Mole weight: 281.27. | |
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