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| Product | Description | |
|---|---|---|
| Psora 4 | Psora 4. Group: Biochemicals. Grades: Purified. CAS No. 724709-68-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Psora 4 | Psora 4 is the most potent small-molecule Kv1.3 blocker known. It blocked Kv1.3 in a use-dependent manner, with a Hill coefficient of 2 and an EC50value of 3 nM, by preferentially binding to the C-type inactivated state of the channel. Synonyms: 4-(4-Phenylbutoxy)-7H-furo[3,2-g][1]benzopyran-7-one. Grades: ≥99% by HPLC. CAS No. 724709-68-6. Molecular formula: C21H18O4. Mole weight: 334.37. |  |
| 4',5'-Dihydro-8-Hydroxy Psoralen | 4',5'-Dihydro-8-hydroxypsoralen is a furancouramin with inhibitory activity on CYP3A4 as well as inhibitory effects on prostaglandin E2 production. 4',5'-Dihydro-8-hydroxypsoralen is an impurity of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 2,3-Dihydro-6,7-dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 2,3-Dihydroxanthotoxol. Grades: Highly Purified. CAS No. 68123-30-8. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 4',5'-Dihydro-8-methoxy Psoralen | 4',5'-Dihydro-8-methoxypsoralen is a furocouramin derivative with insect antifeeding activity. 4',5'-Dihydro-8-methoxypsoralen is dihydro impurity as well as a metabolite of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;2,3-Dihydro-6-hydroxy-7-methoxy-5-benzofuranacrylic Acid δ-Lactone; 4',5'-Dihydro-8-methoxypsoralen; 9-Methoxy-2,3-dihydrofuro[3,2-g]coumarin; NSC 401281. Grades: Highly Purified. CAS No. 3779-3-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 5-(4-Phenoxybutoxy)psoralen | 5-(4-Phenoxybutoxy)psoralen is selective inhibitor of Kv1.3, voltage-gated K+ channel. It potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. It has 23-fold selectivity for Kv1.3 over Kv1.5. It is used in treatment of multiple sclerosis. It was developed by Airmid company and is in Cilinic phase 1. Uses: 5-(4-phenoxybutoxy)psoralen is used in treatment of multiple sclerosis. Synonyms: SPS-4251; SPS 4251; SPS4251; AS-77; PAP-1; AS 77; PAP 1; AS77; PAP1; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)-;4-(4-Phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one;2-g][1]benzopyran-7-one;4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one. Grades: 95%. CAS No. 870653-45-5. Molecular formula: C21H18O5. Mole weight: 350.36. | |
| 5-(4-Phenoxybutoxy)psoralen | ?98% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. |  |
| Bergapten (4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 5-Methoxypsoralen, Bergaptan, Bergaptene, Heraclin, Majudin,5-MOP, Psoraderm-5) | Naturally occurring analog of psoralen and isomer of methoxsalen. Found in a wide variety of plants. Antipsoriatic. Group: Biochemicals. Alternative Names: 4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 5-Methoxypsoralen; Bergaptan; Bergaptene; Heraclin; Majudin;5-MOP, Psoraderm-5. Grades: Highly Purified. CAS No. 484-20-8. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| (+)-Biotin-(PEO)4-psoralen | (+)-Biotin-(PEO)4-psoralen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| (+)-Biotin-(PEO)4-psoralen 99+% (NMR) | (+)-Biotin-(PEO)4-psoralen 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Succinimidyl-[4-(psoralen-8-yloxy)]butyrate | Succinimidyl-[4-(psoralen-8-yloxy)]butyrate. Group: Biochemicals. Alternative Names: Spb. Grades: Highly Purified. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR) | Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| 4'-O-Methylbavachalcone | 4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 20784-60-5. Molecular formula: C21H22O4. Mole weight: 338.4. Purity: 0.9985. Canonical SMILES: O=C(C1=CC(C/C=C(C)\C)=C(OC)C=C1O)/C=C/C2=CC=C(O)C=C2. Product ID: ACM20784605. Alfa Chemistry ISO 9001:2015 Certified. Categories: CHEBI:85123. |  |
| AMT-NHS | AMT-NHS is an RNA-protein crosslinker that can be used to capture different RNA-protein interactions in cells. AMT-NHS consists of a psoralen derivative and an N-hydroxysuccinimide ester group that reacts with the RNA bases and primary amines of proteins, respectively. AMT-NHS can penetrate living yeast cells and cross-link Cbf5 to H/ACA snoRNAs with high specificity. AMT-NHS induces different cross-linking patterns and targets both single-stranded and double-stranded regions of RNA. Synonyms: 2,5-dioxopyrrolidin-1-yl 3-(((2,5,9-trimethyl-7-oxo-7H-furo[3,2-g]chromen-3-yl)methyl)thio)propanoate. Molecular formula: C22H21NO7S. Mole weight: 443.47. | |
| Angelicin | Angelicin, a furocoumarin naturally occurring tricyclic aromatic compound, structurally related to psoralens, is reported to have anti-cancer, antiviral, anti-inflammatory activity.IC50 value: 49.56 μM (cellular cytotoxicity); 5.39 μg/ml (28.95 μM) (against MHV-68)Target:In vitro: In human SH-SY5Y neuroblastoma cells, angelicin increased cellular cytotoxicity in a dose- and time-dependent manner with IC50 of 49.56 μM at 48 h of incubation. Angelicin dose-dependently downregulated the expression of anti-apoptotic proteins including Bcl-2, Bcl-xL, and Mcl-1; Angelicin-induced apoptosis is mediated primarily through the intrinsic caspase-mediated pathway. Angelicin efficiently inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced lytic replication of human gammaherpresviruses in both EBV- and KSHV-infected cells. Angelicin was potentially advantageous to prevent inflammatory diseases by inhibiting NF-κB and MAPK pathways.In vivo: Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 523-50-2. Molecular formula: C11H6O3. Mole weight: 186.16. Purity: 0.9986. Canonical SMILES: O=C1C=CC2=CC=C(OC=C3)C3=C2O1. Product ID: ACM523502. Alfa Chemistry ISO 9001:2015 Certified. | |
| Bakuchiol | Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 ( UGT2B7 ) [2] and human carboxylesterase 2 ( hCE2 ) [3] , with IC 50 s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory [5] , antibacterial [4] , antitumor [1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0235. |  |
| Bergaptol | A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 4-Hydroxybergapten; 5-Hydroxy-6,7-furanocoumarin; 5-Hydroxypsoralen; NSC 341958. Grades: Highly Purified. CAS No. 486-60-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Corylin | Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound.IC50 value:Target:in vitro: Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 53947-92-5. Molecular formula: C20H16O4. Mole weight: 320.34. Purity: 0.98. IUPACName: 3-(2,2-Dimethylchromen-6-yl)-7-hydroxychromen-4-one. Canonical SMILES: CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C. Density: 1.295±0.06 g/ml. Product ID: ACM53947925. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cory in the House. | |
| Neobavaisoflavone | Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 41060-15-5. Molecular formula: C20H18O4. Mole weight: 322.35. Purity: 0.9991. Canonical SMILES: O=C1C(C2=CC=C(O)C(C/C=C(C)\C)=C2)=COC3=CC(O)=CC=C13. Product ID: ACM41060155. Alfa Chemistry ISO 9001:2015 Certified. | |
| Psoralen Azide | Psoralen Azide is a chemical compound used in biomedical research to study DNA damage and repair pathways. It is commonly used to crosslink DNA and proteins, as well as to label proteins with azide groups for subsequent click chemistry reactions. Synonyms: 4'-Azidomethyl-4,5',8-trimethylpsoralen. Molecular formula: C15H13N3O3. Mole weight: 283.28. | |
| Psoralen-C2 CEP | Psoralen-C2 CEP is an innovative biomedical compound, used for studying a myriad of skin afflictions, particularly psoriasand vitiligo. It is derived from psoralen, an organic constituent inherent to select flora. Synonyms: 2-[4'-(hydroxymethyl)-4,5',8-trimethylpsoralen]-ethyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Psoralen C2 Phosphoramidite. Grades: 95%. CAS No. 126221-83-8. Molecular formula: C26H35N2O6P. Mole weight: 502.55. | |
| Psoralen C6 Phosphoramidite | Psoralen C6 Phosphoramidite is an indispensable compound, finding extensive employment in DNA synthesis and modification. This remarkable product effectively facilitates the incorporation of psoralen derivatives into oligonucleotides, thereby enabling the research of an extensive array of afflictions encompassing cancer and dermatological conditions. Synonyms: 6-[4'-(Hydroxymethyl)-4,5',8-trimethylpsoralen]-hexyl-1-O-(2-cyanoethyl)-(N,N-diisopropyl)-phosphoramidite; Phosphoramidous acid, N,N-bis(1-methylethyl)-, 2-cyanoethyl6-[(2,5,9-trimethyl-7-oxo-7H-furo[3,2-g][1]benzopyran-3-yl)methoxy]hexyl ester. CAS No. 518046-08-7. Molecular formula: C30H43N2O6P. Mole weight: 558.65. | |
| Trioxsalen | A derivative of psoralen, which intercalates into DNA and forms DNA single-strand adducts and interstrand crosslinks. Uses: Photoactive probe. Synonyms: 4,5',8-Trimethylpsoralen;2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one;NSC71047; NSC-71047; NSC 71047; Trioxsalen, trimethylpsoralen, Trioxysalen; Trisoralen. Grades: >98.0%(LC). CAS No. 3902-71-4. Molecular formula: C14H12O3. Mole weight: 228.247. | |
| Xanthotoxol | A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities. Group: Biochemicals. Alternative Names: 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 6,7-Dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 3-(6,7-Dihydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone; 8-Hydroxypsoralen; NSC 401269. Grades: Highly Purified. CAS No. 2009-24-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
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