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Psora 4. Group: Biochemicals. Grades: Purified. CAS No. 724709-68-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
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4',5'-Dihydro-8-Hydroxy Psoralen
4',5'-Dihydro-8-hydroxypsoralen is a furancouramin with inhibitory activity on CYP3A4 as well as inhibitory effects on prostaglandin E2 production. 4',5'-Dihydro-8-hydroxypsoralen is an impurity of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 2,3-Dihydro-6,7-dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 2,3-Dihydroxanthotoxol. Grades: Highly Purified. CAS No. 68123-30-8. Pack Sizes: 25mg. US Biological Life Sciences.
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4',5'-Dihydro-8-methoxy Psoralen
4',5'-Dihydro-8-methoxypsoralen is a furocouramin derivative with insect antifeeding activity. 4',5'-Dihydro-8-methoxypsoralen is dihydro impurity as well as a metabolite of 8-Methoxypsoralen , also known as Methoxsalen. Group: Biochemicals. Alternative Names: 2,3-Dihydro-9-methoxy-7H-furo[3,2-g][1]benzopyran-7-one;2,3-Dihydro-6-hydroxy-7-methoxy-5-benzofuranacrylic Acid δ-Lactone; 4',5'-Dihydro-8-methoxypsoralen; 9-Methoxy-2,3-dihydrofuro[3,2-g]coumarin; NSC 401281. Grades: Highly Purified. CAS No. 3779-3-1. Pack Sizes: 25mg. US Biological Life Sciences.
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5-(4-Phenoxybutoxy)psoralen
5-(4-Phenoxybutoxy)psoralen is selective inhibitor of Kv1.3, voltage-gated K+ channel. It potently inhibits human T effector memory cell proliferation and delayed hypersensitivity. It has 23-fold selectivity for Kv1.3 over Kv1.5. It is used in treatment of multiple sclerosis. It was developed by Airmid company and is in Cilinic phase 1. Uses: 5-(4-phenoxybutoxy)psoralen is used in treatment of multiple sclerosis. Synonyms: SPS-4251; SPS 4251; SPS4251; AS-77; PAP-1; AS 77; PAP 1; AS77; PAP1; 7H-Furo[3,2-g][1]benzopyran-7-one, 4-(4-phenoxybutoxy)-; 4-(4-Phenoxybutoxy)-7H-furo[3,2-g][1]benzopyran-7-one; 2-g][1]benzopyran-7-one; 4-(4-phenoxybutoxy)-7H-furo[3,2-g]chromen-7-one. Grade: 95%. CAS No. 870653-45-5. Molecular formula: C21H18O5. Mole weight: 350.36.
Naturally occurring analog of psoralen and isomer of methoxsalen. Found in a wide variety of plants. Antipsoriatic. Group: Biochemicals. Alternative Names: 4-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; 5-Methoxypsoralen; Bergaptan; Bergaptene; Heraclin; Majudin;5-MOP, Psoraderm-5. Grades: Highly Purified. CAS No. 484-20-8. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
(+)-Biotin-(PEO)4-psoralen
(+)-Biotin-(PEO)4-psoralen. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg, 5mg. US Biological Life Sciences.
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(+)-Biotin-(PEO)4-psoralen 99+% (NMR)
(+)-Biotin-(PEO)4-psoralen 99+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 5mg. US Biological Life Sciences.
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Succinimidyl-[4-(psoralen-8-yloxy)]butyrate
Succinimidyl-[4-(psoralen-8-yloxy)]butyrate. Group: Biochemicals. Alternative Names: Spb. Grades: Highly Purified. Pack Sizes: 10mg, 25mg, 50mg. US Biological Life Sciences.
Succinimidyl-[4-(psoralen-8-yloxy)]butyrate 99.5+% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 50mg. US Biological Life Sciences.
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4'-O-Methylbavachalcone
4'-O-Methylbavachalcone is a chalcone isolated from Psoralea corylifolia, inhibits severe acute respiratory syndrome coronavirus (SARS-CoV) papain-like protease (PLpro) activity, with an IC50 of 10.1 μM. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 20784-60-5. Molecular formula: C21H22O4. Mole weight: 338.4. Purity: 0.9985. Canonical SMILES: O=C(C1=CC(C/C=C(C)\C)=C(OC)C=C1O)/C=C/C2=CC=C(O)C=C2. Product ID: ACM20784605. Alfa Chemistry ISO 9001:2015 Certified. Categories: CHEBI:85123.
4'-O-Methylbroussochalcone B
4'-O-Methylbroussochalcone B is a natural chalcone found in the seeds of Psoralea corylifolia Linn. Synonyms: (2E)-1-[2-Hydroxy-4-methoxy-5-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one; 2-Propen-1-one, 1-[2-hydroxy-4-methoxy-5-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (E)-; 2',4-Dihydroxy-4'-methoxy-5'-(3-methyl-2-butenyl)chalcone; 4'-O-Methylbavachalcone; O-Methylbroussochalcone B. Grade: >97%. CAS No. 20784-60-5. Molecular formula: C21H22O4. Mole weight: 338.40.
8-Prenyldaidzein
8-Prenyldaidzein is a natural flavonoid found in the seeds of Psoralea corylifolia L. 8-Prenyldaidzein has cytotoxic properties against P-388 cells and antioxidant activity against DPPH radical scavenging. Uses: Cytotoxic, antioxidant. Synonyms: 3-(4-Hydroxyphenyl)-7-hydroxy-8-(3-methyl-2-butenyl)-4H-1-benzopyran-4-o ne. Grade: >98%. CAS No. 135384-00-8. Molecular formula: C20H18O4. Mole weight: 322.36.
Angelicin
Angelicin, a furocoumarin naturally occurring tricyclic aromatic compound, structurally related to psoralens, is reported to have anti-cancer, antiviral, anti-inflammatory activity.IC50 value: 49.56 μM (cellular cytotoxicity); 5.39 μg/ml (28.95 μM) (against MHV-68)Target:In vitro: In human SH-SY5Y neuroblastoma cells, angelicin increased cellular cytotoxicity in a dose- and time-dependent manner with IC50 of 49.56 μM at 48 h of incubation. Angelicin dose-dependently downregulated the expression of anti-apoptotic proteins including Bcl-2, Bcl-xL, and Mcl-1; Angelicin-induced apoptosis is mediated primarily through the intrinsic caspase-mediated pathway. Angelicin efficiently inhibited 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced lytic replication of human gammaherpresviruses in both EBV- and KSHV-infected cells. Angelicin was potentially advantageous to prevent inflammatory diseases by inhibiting NF-κB and MAPK pathways.In vivo: Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 523-50-2. Molecular formula: C11H6O3. Mole weight: 186.16. Purity: 0.9986. Canonical SMILES: O=C1C=CC2=CC=C(OC=C3)C3=C2O1. Product ID: ACM523502. Alfa Chemistry ISO 9001:2015 Certified.
Bakuchiol
Bakuchiol is a phytoestrogen isolated from the seeds of Psoralea corylifolia L with anti-tumor, antioxidant, and antibacterial effects. Bakuchiol has a retinol-like effect on skin gene expression and properties. Bakuchiol inhibits DNA polymerase and UDP-glucuronosyltransferase 2B7 (IC50 = 41 μM). Bakuchiol has hypoglycemic, hypolipidemic, anti-inflammatory, anti-wrinkle, soothing and liver protective, anticancer, antidepressant, and estrogen-like effects. Uses: Antioxidant. Synonyms: Drupanol; Chiba; NSC-671195; NSC671195; NSC 671195; UP-256; UP256; UP 256; W1975; W 1975; W-1975; 4-[(1E,3S)-3-Ethenyl-3,7-dimethyl-1,6-octadien-1-yl]phenol; Phenol, 4-(3-ethenyl-3,7-dimethyl-1,6-octadienyl)-, [S-(E)]-; Phenol, 4-[(1E,3S)-3-ethenyl-3,7-dimethyl-1,6-octadienyl]-; (+)-Bakuchiol; (S)-(+)-Bakuchiol; (S)-Bakuchiol; Bakutrol; Neuvachiol; Sytenol A. Grade: 98%. CAS No. 10309-37-2. Molecular formula: C18H24O. Mole weight: 256.38.
Bakuchiol
Bakuchiol is a phytoestrogen that can be obtained from psoralen seeds. Bakuchiol has been proven to be a non-competitive inhibitor of multiple enzymes, including UDP-glucuronosyltransferase 2B7 ( UGT2B7 ) [2] and human carboxylesterase 2 ( hCE2 ) [3] , with IC 50 s values of 40.9 μM and 7.28 μM, respectively. Bakuchiol exhibits significant research and application potential in areas such as anti-inflammatory [5] , antibacterial [4] , antitumor [1] therapies, as well as drug metabolism regulation. Uses: Scientific research. Group: Natural products. Alternative Names: (S)-(+)-Bakuchiol. CAS No. 10309-37-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0235.
Bavachin
Bavachin, a natural phytoestrogen found in the fruits of Psoralea corylifolia L, potentially protects cartilage from inflammation-mediated damage in joints of osteoarthritis patients through decreasing IL-1β-induced activation of IKK-IκBα-NF-κB signaling pathway. Bavachin also exhibits the activities of antioxidant, antimutagenic and weak phytoestrogen by binding and activating the estrogen receptor. Synonyms: 4H-1-benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-6-(3-methyl-2-buten -1-yl)-; 7-Hydroxy-2-(4-hydroxyphenyl)-6-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen -4-one. Grade: >98%. CAS No. 19879-32-4. Molecular formula: C20H20O4. Mole weight: 324.4.
Bergaptol
A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties. Group: Biochemicals. Alternative Names: 4-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 4-Hydroxybergapten; 5-Hydroxy-6,7-furanocoumarin; 5-Hydroxypsoralen; NSC 341958. Grades: Highly Purified. CAS No. 486-60-2. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
Byakangelicin
Byakangelicin is an effective inhibitor of sex hormones and affects the catabolism of endogenous hormones. It directly affects the cytochrome P450 isoform (CY) P3A4 in human hepatocytes. It is an inhibitor of aldose reductase used in the treatment of diabetic cataracts. Byakangelicin is a natural coumarin compound found in Murraya koenigii, Triphasia trifoliata, and other organisms. Synonyms: 7H-Furo[3,2-g][1]benzopyran-7-one, 9-[(2R)-2,3-dihydroxy-3-methylbutoxy]-4-methoxy-; 7H-Furo[3,2-g][1]benzopyran-7-one, 9-(2,3-dihydroxy-3-methylbutoxy)-4-methoxy-, (R)-; 9-[(2R)-2,3-Dihydroxy-3-methylbutoxy]-4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Biacangelicin; (+)-Byakangelicin; 5-Methoxy-8-(2,3-dihydroxy-3-methylbutoxy)psoralene; Bjacangelicin; Bjakangelicin; Byankagelicine. Grade: >98%. CAS No. 482-25-7. Molecular formula: C17H18O7. Mole weight: 334.32.
Corylifol C
Corylifol C isolated from the seeds of Psoralea corylifolia L. Synonyms: 2-(3,4-Dihydroxyphenyl)-7-hydroxy-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one. Grade: 0.95. CAS No. 775351-91-2. Molecular formula: C20H18O5. Mole weight: 338.4.
Corylin
Corylin is a major bioactive compound isolated from Psoralea corylifolia L; antibiotic or anticancer compound.IC50 value:Target:in vitro: Corylin showed an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 value of 1.37 uM. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 53947-92-5. Molecular formula: C20H16O4. Mole weight: 320.34. Purity: 0.98. IUPACName: 3-(2,2-Dimethylchromen-6-yl)-7-hydroxychromen-4-one. Canonical SMILES: CC1(C=CC2=C(O1)C=CC(=C2)C3=COC4=C(C3=O)C=CC(=C4)O)C. Density: 1.295±0.06 g/ml. Product ID: ACM53947925. Alfa Chemistry ISO 9001:2015 Certified. Categories: Cory in the House.
Corylin
Corylin is a major bioactive compound isolated from Psoralea corylifolia L. It is antibiotic or anticancer compound. Uses: Anti-biotic; anti-cancer. Synonyms: 7-Hydroxy-2',2'-dimethyl-2'H,4H-3,6'-bichromen-4-one. Grade: >98%. CAS No. 53947-92-5. Molecular formula: C20H16O4. Mole weight: 320.34.
Erythrinin C
Erythrinin C is a natural plant flavonoid isolated from the seeds of Psoralea corylifolia Linn. Synonyms: 2-(1-Methyl-1-hydroxyethyl)-4-hydroxy-6-(4-hydroxyphenyl)-2,3-dihydro-5H-furo[3,2-g][1]benzopyran-5-one; 2,3-Dihydro-2-(1-hydroxy-1-methylethyl)-4-hydroxy-6-(4-hydroxyphenyl)-5H-furo[3,2-g][1]benzopyran-5-one. Grade: >98%. CAS No. 63807-85-2. Molecular formula: C20H18O6. Mole weight: 354.4.
Isobavachin
Isobavachin is a flavonoid isolated from Psoralea morisiana. It was shown to promote neurogenesis of mouse embryonic stem cells. Synonyms: (2S)-7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one. Grade: >98%. CAS No. 31524-62-6. Molecular formula: C20H20O4. Mole weight: 324.4.
Neobavaisoflavone
Neobavaisoflavone, a flavonoid, is isolated from the seeds of Psoralea corylifolia. Neobavaisoflavone exhibits anti-inflammatory, anti-cancer and anti-oxidation activities. Neobavaisoflavone inhibits DNA polymerase at moderate to high concentrations. Neobavaisoflavone also inhibits platelet aggregation. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. Appearance: Solid. CAS No. 41060-15-5. Molecular formula: C20H18O4. Mole weight: 322.35. Purity: 0.9991. Canonical SMILES: O=C1C(C2=CC=C(O)C(C/C=C(C)\C)=C2)=COC3=CC(O)=CC=C13. Product ID: ACM41060155. Alfa Chemistry ISO 9001:2015 Certified.
PAP-1
PAP-1 (5-(4-Phenoxybutoxy)psoralen) is a potent, selective, and orally active Kv1.3 blocker (EC50=2 nM). PAP-1 blocks Kv1.3 in a use-dependent manner and acts by preferentially binding to the C-type inactivated state of the channel. PAP-1 exhibits 23-fold selectivity over Kv1.5 (EC50=45 nM), and further displays 33- to 125-fold selectivity over all other Kv1-family channels. PAP-1 does not exhibit cytotoxic or phototoxic effects[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: 5-(4-Phenoxybutoxy)psoralen. CAS No. 870653-45-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10015.
Xanthotoxol
A hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been shown to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent studies show that it may also have antioxidant and anticancer activities. Group: Biochemicals. Alternative Names: 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one; 6,7-Dihydroxy-5-benzofuranacrylic Acid δ-Lactone; 3-(6,7-Dihydroxy-5-benzofuranyl)-2-propenoic Acid δ-Lactone; 8-Hydroxypsoralen; NSC 401269. Grades: Highly Purified. CAS No. 2009-24-7. Pack Sizes: 25mg. US Biological Life Sciences.
Worldwide
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