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| Product | Description | |
|---|---|---|
| Pyrazinecarbonitrile,3-amino-6-(1-methylethyl)-,4-oxide(9ci) | Pyrazinecarbonitrile,3-amino-6-(1-methylethyl)-,4-oxide(9ci). Uses: Designed for use in research and industrial production. Additional or Alternative Names: CTK4J2909, AG-F-70333, 3-AMINO-6-(ISOPROPYL)PYRAZINE-2-CARBONITRILE 4-OXIDE, 50627-15-1. Product Category: Heterocyclic Organic Compound. CAS No. 50627-15-1. Molecular formula: C8H10N4O. Mole weight: 178.1912. Purity: 0.96. IUPACName: 4-hydroxy-3-imino-6-propan-2-ylpyrazine-2-carbonitrile. Product ID: ACM50627151. Alfa Chemistry ISO 9001:2015 Certified. |  |
| 2-Pyrazinecarbonitrile,3-amino-6-methyl-,4-oxide | 2-Pyrazinecarbonitrile,3-amino-6-methyl-,4-oxide. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 19994-56-0, 2-AMINO-3-CYANO-5-METHYLPYRAZINE 1-OXIDE, SureCN312864, AGN-PC-00PZ47, CTK4E2986, AR2267, AKOS006282151, AG-E-46291, KB-167021, BB 0260950, 2-AMINO-3-CYANO-5-METHYLPYRAZINE-1-OXIDE, 4-hydroxy-3-imino-6-methylpyrazine-2-carbonitrile, 2-Pyrazinecarbonitrile,3-amino-6-methyl-, 4-oxide, I14-40175, Pyrazinecarbonitrile,3-amino-6-methyl-, 4-oxide (8CI,9CI). Product Category: Heterocyclic Organic Compound. CAS No. 19994-56-0. Molecular formula: C6H6N4O. Mole weight: 150.13. Purity: 0.96. IUPACName: 4-hydroxy-3-imino-6-methylpyrazine-2-carbonitrile. Canonical SMILES: CC1=CN(C(=N)C(=N1)C#N)O. Product ID: ACM19994560. Alfa Chemistry ISO 9001:2015 Certified. | |
| 2-Amino-3-cyano-5-methylpyrazine-1-oxide | 2-Amino-3-cyano-5-methylpyrazine-1-oxide. Group: Biochemicals. Alternative Names: 3-Amino-6-methyl-pyrazinecarbonitrile-4-oxide. Grades: Highly Purified. CAS No. 19994-56-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences. |  Worldwide |
| 2-Chloro-5-cyanopyrazine | 2-Chloro-5-cyanopyrazine. Group: Biochemicals. Alternative Names: 5-Chloro-2-pyrazinecarbonitrile. Grades: Highly Purified. CAS No. 36070-75-4. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| CCT244747 | CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inhibitor with potential anticancer activity. CCT244747 inhibited cellular CHK1 activity (IC(50) 29-170 nmol/L), significantly enhanced the cytotoxicity of several anticancer drugs, and abrogated drug-induced S and G(2) arrest in multiple tumor cell lines. CCT244747 represents the first structural disclosure of a highly selective, orally active CHK1 inhibitor and warrants further evaluation alone or combined with genotoxic anticancer therapies. Synonyms: CCT-244747; CCT 244747; 3-{[(2R)-1-(Dimethylamino)-2-propanyl]oxy}-5-{[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino}-2-pyrazinecarbonitrile; 3-[(1R)-2-(Dimethylamino)-1-methylethoxy]-5-[[4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-2-pyridinyl]amino]-2-pyrazinecarbonitrile; (R)-3-((1-(dimethylamino)propan-2-yl)oxy)-5-((4-methoxy-5-(1-methyl-1H-pyrazol-4-yl)pyridin-2-yl)amino)pyrazine-2-carbonitrile. Grades: ≥98%. CAS No. 1404095-34-6. Molecular formula: C20H24N8O2. Mole weight: 408.46. |  |
| Prexasertib mesylate | Prexasertib, also known as LY2606368, is an ATP-competitive CHK1 inhibitor (Ki= 0.9 nmol/L), with minor activity against CHK2 and RSK with IC50= 8 nM and 9 nM respectively in cell-free assay. Treatment of cells with LY2606368 results in the rapid appearance of TUNEL and pH2AX-positive double-stranded DNA breaks in the S-phase cell population. Synonyms: 2-Pyrazinecarbonitrile, 5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)-, methanesulfonate; Prexasertib mesylate; LY2606368; LY-2606368; LY 2606368. CAS No. 1234015-55-4. Molecular formula: C19H23N7O5S. Mole weight: 461.49. | |
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