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Pyridone 6. Group: Biochemicals. Alternative Names: 2-(1,1-Dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5-f]isoquinolin-7-one;CMP 6. Grades: Highly Purified. CAS No. 457081-03-7. Pack Sizes: 1mg. Molecular Formula: C18H16FN3O, Molecular Weight: 309.339999999999. US Biological Life Sciences.
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Pyridone 6
Pyridone 6 is a pan-JAK inhibitor, which potently inhibits the JAK kinase family, with IC 50 s of 1 nM for JAK2 and TYK2 , 5 nM for JAK3 , and 15 nM for JAK1 , while displaying significantly weaker affinities (130 nM to >10 mM) for other protein tyrosine kinases. Uses: Scientific research. Group: Signaling pathways. CAS No. 457081-03-7. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14435.
Pyridone 6
Pyridone 6 is a potent and selective inhibitor of JAK1, JAK2, JAK3, and Tyk2, displaying significantly weaker affinities for other protein tyrosine kinases. It was shown to block IL-2 and IL-4-dependent proliferation of mouse T-cell lymphoma cells. Synonyms: Pyridone 6; Pyridone-6; Pyridone6; CMP 6; JAK Inhibitor I; Janus-Associated Kinase Inhibitor I. Grades: >98%. CAS No. 457081-03-7. Molecular formula: C18H16FN3O. Mole weight: 309.34.
1,1-Thiocarbonyldi-2(1H)-pyridone
1,1-Thiocarbonyldi-2(1H)-pyridone is a reagent used in the synthesis of sulfur heterocycles via domino metal-mediated reactions. Also used as a reagent in the synthesis of Neomycin-?Neomycin dimer which displays high affinity for AT-Rich DNA Duplexes. Group: Biochemicals. Grades: Highly Purified. CAS No. 102368-13-8. Pack Sizes: 500mg, 1g. Molecular Formula: C11H8N2O2S, Molecular Weight: 232.26. US Biological Life Sciences.
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1,1'-Thiocarbonyldi-2(1H)-pyridone
1,1'-Thiocarbonyldi-2(1H)-pyridone. Group: Biochemicals. Grades: Highly Purified. CAS No. 102368-13-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C11H8N2O2S. US Biological Life Sciences.
1-(4-Benzyloxyphenyl)-5-methyl-2(1H)-pyridone. Group: Biochemicals. Alternative Names: 5-Methyl-1-[4-(phenylmethoxy)phenyl]-2(1H)-pyridinone. Grades: Highly Purified. CAS No. 1076199-02-4. Pack Sizes: 10mg. US Biological Life Sciences.
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1-(4-Benzyloxyphenyl)-5-methyl-2(1H)-pyridone
Heterocyclic Organic Compound. Alternative Names: 1-(4-Benzyloxyphenyl)-5-methyl-2(1H)-pyridone. CAS No. 1076199-02-4. Molecular formula: C19H17NO2. Mole weight: 291.34378. Appearance: Off-White to White Solid. Catalog: ACM1076199024.
1-Methyl-2-pyridone
1-Methyl-2-pyridone. Group: Biochemicals. Grades: Highly Purified. CAS No. 694-89-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. US Biological Life Sciences.
1-O-(5-Carboxy-N-phenyl-2-(1H)-pyridone)-D-glucuronide is a metabolite of glucuronide that has proven useful for the identification and diagnosis of drug-induced liver injury, specifically that caused by Acetaminophen. Additionally, it has been employed in the investigational study of liver metabolism and the determination of hepatic impairment induced by a range of other drugs. The potential applications of this compound are broad and could significantly enhance the clinical management of such complications. Molecular formula: C18H17NO9. Mole weight: 391.33.
1-Phenethyl-2-pyridone
1-Phenethyl-2-pyridone is used in the degradation, identification and in analysis of impurities of fentanyl. Also acts as a reagent for the synthesis and antitumor activities of lactams and pyridones related compounds. Group: Biochemicals. Grades: Highly Purified. CAS No. 18065-78-6. Pack Sizes: 10mg, 25mg. Molecular Formula: C13H13NO, Molecular Weight: 199.25. US Biological Life Sciences.
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1-Phenethyl-2-pyridone-d5
1-Phenethyl-2-pyridone-d5 is an isotope labelled compound of 1-Phenethyl-2-pyridone (P321315). 1-Phenethyl-2-pyridone is used in the degradation, identification and in analysis of impurities of fentanyl. Also acts as a reagent for the synthesis and antitumor activities of lactams and pyridones related compounds. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C13H8D5NO, Molecular Weight: 204.28. US Biological Life Sciences.
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1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone
1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone is an intermediate in the synthesis of Perampanel (P285522), an antiepileptic drug. Group: Biochemicals. Grades: Highly Purified. CAS No. 381725-50-4. Pack Sizes: 500mg, 1g. Molecular Formula: C16H12N2O. US Biological Life Sciences.
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1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone-d5
1-Phenyl-5-(pyridin-2-yl)-2(1H)-pyridone-d5 is an intermediate in the synthesis of Perampanel-d5, which is the labeled analogue of Perampanel (P285520), an antiepileptic drug. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C16H7D5N2O. US Biological Life Sciences.
3,5-Dinitro-2-pyridone. Group: Biochemicals. Grades: Reagent Grade. CAS No. 2980-33-8. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
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3-Acetyl-2(1H)-pyridone
3-Acetyl-2(1H)-pyridone is a general chemical reagent used in the synthesis of 2,3-disubstituted pyridines. Also used in the synthesis of quinolones. Group: Biochemicals. Grades: Highly Purified. CAS No. 62838-65-7. Pack Sizes: 100mg, 250mg. Molecular Formula: C7H7NO2, Molecular Weight: 137.139999999999. US Biological Life Sciences.
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3-Chloro-2-pyridone
3-Chloro-2-pyridone. Group: Biochemicals. Grades: Highly Purified. CAS No. 13466-35-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H4ClNO. US Biological Life Sciences.
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3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
A chelator that could replace disferrioxamine. It is orally and parenterally effective in the removal of iron in vivo from rabbits and mice and also from transferrin and ferritin in vitro. Synonyms: 3-hydroxy-1,2-dimethylpyridin-4-one. Grades: 99 %. CAS No. 30652-11-0. Molecular formula: C7H9NO2. Mole weight: 139.15.
3-Hydroxy-5-Methyl-N-Hydroxyphenyl-2-1H-Pyridone
3-Hydroxy-5-Methyl-N-Hydroxyphenyl-2-1H-Pyridone is a deuterated labelled of Pirfenidone which is an inhibitor of TGF-β production and TGF-&beta. stimulated collagen production. Grades: > 95%. Molecular formula: C12H11NO3. Mole weight: 217.23.
3-Hydroxy-5-methyl-N-phenyl-2-1H-pyridone
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
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3-Hydroxy-5-Methyl-N-Phenyl-2-1H-Pyridone
3-Hydroxy-5-Methyl-N-Phenyl-2-1H-Pyridone is a deuterated metabolite of Pirfenidone which reduces production of TNF-α and IL-1&beta. Grades: > 95%. CAS No. 887406-53-3. Molecular formula: C12H11NO2. Mole weight: 201.23.
3-Hydroxy-5-methyl-N-phenyl-2-1H-pyridone-d5
A deuterated metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Alternative Names: 3-Hydroxy-5-methyl-1-(phenyl-2,3,4,5,6-d5)-2(1H)-pyridinone. Grades: Highly Purified. CAS No. 1020719-53-2. Pack Sizes: 1mg. Molecular Formula: C??H?D?NO?, Molecular Weight: 206.25. US Biological Life Sciences.
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3-Hydroxy-5-methyl-N-phenyl-2-1H-pyridone-d5
Heterocyclic Organic Compound. Alternative Names: 3-HYDROXY-5-METHYL-N-PHENYL-2-1H-PYRIDONE-D5. CAS No. 1020719-53-2. Molecular formula: C12H6D5NO2. Mole weight: 206.25. Appearance: White Crystalline Solid. Catalog: ACM1020719532.
3-Methoxy-2(1H)-pyridone
3-Methoxy-2(1H)-pyridone. CAS No: 20928-63-6
Sarchem Laboratories New Jersey NJ
3-Methyl-2-pyridone
3-Methyl-2-pyridone. Group: Biochemicals. Alternative Names: 2-Hydroxy-3-methylpyridine; 3-Methyl-2-pyridinone. Grades: Highly Purified. CAS No. 1003-56-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C6H7NO. US Biological Life Sciences.
Heterocyclic Organic Compound. CAS No. 113411-97-5. Catalog: ACM113411975.
5-Carboxy-N-phenyl-2-1H-pyridone
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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5-Carboxy-N-Phenyl-2-1H-Pyridone
5-Carboxy-N-Phenyl-2-1H-Pyridone is a deuterated metabolite of Pirfenidone which has anti-fibrotic and anti-inflammatory properties. Synonyms: 1,6-Dihydro-6-oxo-1-phenyl-3-pyridinecarboxylic Acid; 6-Oxo-1-phenyl-1,6-dihydropyridine-3-carboxylic Acid; 5-Carboxy Pirfenidone. Grades: > 95%. CAS No. 77837-08-2. Molecular formula: C12H9NO3. Mole weight: 215.21.
5-Carboxy-N-phenyl-2-1H-pyridone-d5
A deuterated metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
5-Hydroxy-2-pyridone
5-Hydroxy-2-pyridone is a metabolite of Pyriproxyfen (P998850); a pyridine-based pesticide used against a variety of arthropoda, in particular to protect cotton crops against whitefly. Group: Biochemicals. Grades: Highly Purified. CAS No. 5154-1-8. Pack Sizes: 100mg, 250mg. Molecular Formula: C5H5NO2, Molecular Weight: 111.1. US Biological Life Sciences.
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5-Hydroxymethyl-N-phenyl-2-1H-pyridone
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
5-Hydroxymethyl-N-Phenyl-2-1H-Pyridone
5-Hydroxymethyl-N-Phenyl-2-1H-Pyridone is an inhibitor for TGF-β production and TGF-β stimulated collagen production with anti-fibrotic and anti-inflammatory properties. Synonyms: 5-(Hydroxymethyl)-1-phenyl-2(1H)-pyridinone 5-Hydroxymethyl Pirfenidone. Grades: > 95%. CAS No. 887406-49-7. Molecular formula: C12H11NO2. Mole weight: 201.23.
5-Hydroxymethyl-N-phenyl-2-1H-pyridone-d5
A deuterated metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
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5-Hydroxymethyl-N-phenyl-2-1H-pyridone-d5
Heterocyclic Organic Compound. Alternative Names: 5-HYDROXYMETHYL-N-PHENYL-2-1H-PYRIDONE-D5. CAS No. 1020719-52-1. Molecular formula: C12H6D5NO2. Mole weight: 206.25. Appearance: Off-White to Pale Yellow Solid. Purity: 0.96. IUPACName: 5-(hydroxymethyl)-1-(2,3,4,5,6-pentadeuteriophenyl)pyridin-2-one. Canonical SMILES: C1=CC=C(C=C1)N2C=C(C=CC2=O)CO. Catalog: ACM1020719521.
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
5-Methyl-N-phenyl-2-1H-pyridone
5-Methyl-N-phenyl-2-1H-pyridone. Group: Biochemicals. Alternative Names: 5-Methyl-1-phenyl-2(1H)pyridinone; Pirfenidone. Grades: Highly Purified. CAS No. 53179-13-8. Pack Sizes: 2g, 5g, 10g, 25g, 50g. US Biological Life Sciences.
Worldwide
5-Methyl-N-phenyl-2-1H-pyridone-d5
A deuterated metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Heterocyclic Organic Compound. Alternative Names: Pirfenidone-d5. CAS No. 1020719-62-3. Molecular formula: C12H6D5NO. Mole weight: 190.25. Appearance: Off-White Solid. Catalog: ACM1020719623.
5-Methyl-N-phenyl-2-1H-pyridone (Pirfenidone)
Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. Group: Biochemicals. Alternative Names: Pirfenidone. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
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5-Trifluoromethyl-2-thio-pyridone
5-Trifluoromethyl-2-thio-pyridone. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
6-Amino-5-nitro-3-(2'-deoxy-b-D-ribofuranosyl)-2(1H)-pyridone, commonly employed in the biomedical sector, is a formidable antiviral agent. Renowned for its effectiveness against an assortment of viral infections, such as hepatitis B and C, this compound exerts its influence by impeding viral replication. By inhibiting the viral RNA-dependent DNA polymerase, it effectively curtails viral proliferation. Grades: 90%. CAS No. 642460-95-5. Molecular formula: C10H13N3O6. Mole weight: 271.23.
JAK Inhibitor I (P6, DBI, (2-(1,1-Dimethylethyl)-9-fluoro-3,6-dihydro-7H-benz[h]-imidaz[4,5-f]isoquinolin-7-one, Pyridone 6, JAK1 Inhibitor I, JAK3 Inhibitor VII, JAK2 Inhibitor I)
A potent, reversible, cell-permeable, and ATP-competitive inhibitor of Janus protein tyrosine kinases (JAKs). Displays potent inhibitory activity against JAK1 (IC50=15nM for murine JAK1), JAK2 (IC50=1nM), JAK3 (Ki=5nM), and Tyk2 (IC50=1nM). Inhibits other kinases at much higher concentrations. Shown to inhibit IL2- and IL4-dependent proliferation of CTLL cells and block the phosphorylation of STAT5; and further induce growth inhibition of multiple myeloma cells expressing activated JAKs and STAT3, unlike AG 490. A 10mM solution of JAK Inhibitor I in DMSO is also available. Group: Biochemicals. Grades: Highly Purified. CAS No. 457081-03-7. Pack Sizes: 500ug, 1mg. US Biological Life Sciences.
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Methyl 5-Carboxy-N-phenyl-2-1H-pyridone
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone
A metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
N-(4-Hydroxyphenyl)-5-Methyl-2-1H-Pyridone
N-(4-Hydroxyphenyl)-5-Methyl-2-1H-Pyridone is a deuterated metabolite of Pirfenidone which has anti-fibrotic and anti-inflammatory properties. Synonyms: 1-(4-Hydroxyphenyl)-5-methyl-2(1H)-pyridinone; F 351. Grades: > 95%. CAS No. 851518-71-3. Molecular formula: C12H11NO2. Mole weight: 201.23.
N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone-d4
A deuterated metabolite of Pirfenidone, a new drug to treat patients with kidney disease who have diabetes. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone-d4
Heterocyclic Organic Compound. Alternative Names: N-(4-HYDROXYPHENYL)-5-METHYL-2-1H-PYRIDONE-D4. CAS No. 1188263-50-4. Molecular formula: C12H7D4NO2. Mole weight: 205.25. Appearance: White Solid. Catalog: ACM1188263504.
N-Methyl-2-Pyridone 5-Carboxylic Acid
A metabolite of Nicotine,which is a potent parasympathomimetic stimulant. Synonyms: N-Methyl-2-Pyridone 5-Carboxylic Acid. Grades: > 95%. Molecular formula: C7H7NO3. Mole weight: 153.14.
N-Methyl-4-pyridone-3-carboxamide
Cas No. 769-49-3.
N-Methyl-4-pyridone-3-carboxamide
N-Methyl-4-pyridone-3-carboxamide. Group: Biochemicals. Alternative Names: 4-Py. Grades: Highly Purified. CAS No. 769-49-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C7H8N2O2. US Biological Life Sciences.
Omeprazole Pyridone Acid Sodium Salt is an impurity of Omeprazole. Omeprazole is a proton pump inhibitor used in the treatment of dyspepsia. It binds to the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase) and inhibits its activity and the parietal cell secretion of H+ ions into the gastric lumen. Synonyms: Sodium 1-(6-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylate; Sodium 1-(5-methoxy-1H-benzo[d]imidazol-2-yl)-3,5-dimethyl-4-oxo-1,4-dihydropyridine-2-carboxylate; Omeprazole Hydrolysis Impurity. Grades: >95%. Molecular formula: C16H14N3NaO4. Mole weight: 335.29.
1-(2,3,5-Tri-O-benzoyl-b-D-ribofuranosyl)-5-Nitropyridine-2(1H)-One, a cyclin-dependent kinase 9 (CDK9) inhibitor, has exhibited a compelling potential against malignancies such as breast cancer, prostate cancer and multiple myeloma. It interferes with the propagation and fission of cancer-bearing cells, ultimately restraining the pathogenesis of the malady. This product has shown noteworthy efficacy in the discovery and evolution of progressive anti-tumor therapies whilst facilitating CDK9 inhibition`s related research undertakings. Synonyms: 5-nitro-1-(2',3',5'-tri-O-benzoyl-beta-ribofuranosyl)-2-pyridone; 5-nitro-1-(2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)-2-pyridone; (2R,3R,4R,5R)-2-((Benzoyloxy)methyl)-5-(5-nitro-2-oxopyridin-1(2H)-yl)tetrahydrofuran-3,4-diyl dibenzoate; 2(1H)-Pyridinone, 5-nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-. Grades: ≥95%. CAS No. 59892-37-4. Molecular formula: C31H24N2O10. Mole weight: 584.53.
1,6-Dihydro-2-(hydroxymethyl)-6-oxo-[3,4'-bipyridine]-5-carbonitrile. Group: Biochemicals. Alternative Names: 3-Cyano-6-hydroxymethyl-5-(4-pyridyl)-2-pyridone. Grades: Highly Purified. CAS No. 99462-32-5. Pack Sizes: 10mg. Molecular Formula: C12H9N3O2, Molecular Weight: 227.22. US Biological Life Sciences.
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1-Ethyl-3-hydroxy-2-methyl-4-pyridinone
1-Ethyl-3-hydroxy-2-methyl-4-pyridinone. Group: Biochemicals. Alternative Names: 1-Ethyl-3-hydroxy-2-methyl-4(1H)-pyridinone; 1-Ethyl-2-methyl-3-hydroxy-4-pyridone; CP 21. Grades: Highly Purified. CAS No. 30652-12-1. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C8H11NO2. US Biological Life Sciences.
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1-Hydroxycyclopentane carboxylic Acid
1-Hydroxycyclopentane carboxylic Acid is a reagent used in the preparation of pyridone-conjugated monobactam antibiotics showing gram-negative activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 16841-19-3. Pack Sizes: 1g, 2.5g. Molecular Formula: C6H10O3, Molecular Weight: 130.139999999999. US Biological Life Sciences.
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2-Acetylamino-4-methylpyridine
2-Acetylamino-4-methylpyridine is a chemical reagent used in the synthesis of potent inhibitors of Eimeria tenalla cGMP-dependant protein kinase as antiparasitic agents. Also used in the 1-pot synthesis of difluoromethyl-2-pyridone derivatives. Group: Biochemicals. Grades: Highly Purified. CAS No. 5327-32-2. Pack Sizes: 5g, 25g. Molecular Formula: C8H10N2O, Molecular Weight: 150.18. US Biological Life Sciences.
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2-Cyano-N-methylacetamide
2-Cyano-N-methylacetamide is used in the synthesis of pyridone compounds and benzimidazoles, for various pharmaceutical application. Group: Biochemicals. Alternative Names: 2-Cyano-N-methylacetamide; Cyanoacetic Acid Methylamide; Cyanoacetic Acid Monomethylamide; N-Methyl-2-cyanoacetamide; N-Methylcyanoacetamide; NSC 47005. Grades: Highly Purified. CAS No. 6330-25-2. Pack Sizes: 1g. US Biological Life Sciences.
2-Methoxy-6- (4- (trifluoromethyl) phenyl) pyridine is a synthetic reagent used in the preparation of substituted pyrazinone, pyrimidinone and pyridone compounds. Group: Biochemicals. Grades: Highly Purified. CAS No. 1202026-99-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H10F3NO, Molecular Weight: 253.22. US Biological Life Sciences.
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