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Pyrimidine is a heterocyclic organic molecule present in many pharmaceutical and naturally derived compounds. Used in the synthesis and discovery of antiviral medication, such as in the case of HIV and HSV. Also used in the synthesis of potent inhibitors of 15-lipoxygenase in the reduction of the release of leukotrienes. Group: Biochemicals. Alternative Names: 1,3-Diazabenzene; 1,3-Diazine; Metadiazine; Miazine; NSC 89305; m-Diazine. Grades: Highly Purified. CAS No. 289-95-2. Pack Sizes: 5g. US Biological Life Sciences.
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Pyrimidine
Pyrimidine is an endogenous metabolite. Uses: Scientific research. Group: Natural products. CAS No. 289-95-2. Pack Sizes: 10 mM * 1 mL; 1 g. Product ID: HY-Y0519.
Pyrimidine,2-(1H-pyrrol-1-yl)-(9ci)
Heterocyclic Organic Compound. CAS No. 114646-17-2. Catalog: ACM114646172.
Pyrimidine-2-carboxylic acid 98+% (HPLC)
Pyrimidine-2-carboxylic acid 98+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Pyrimidine,2-(chloromethyl)-5-methyl
Heterocyclic Organic Compound. Alternative Names: Pyrimidine, 2-(chloromethyl)-5-methyl;Pyrimidine, 2-(chloromethyl)-5-methyl- (9CI);2-Chloromethyl-5-Methylpyrimidine. CAS No. 126504-85-6. Molecular formula: C6H7ClN2. Mole weight: 142.58618. Catalog: ACM126504856.
Pyrimidine-4-carboxylic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 31462-59-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C5H4N2O2. US Biological Life Sciences.
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Pyrimidine-4-carboxylic acid
Pyrimidine-4-carboxylic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 31462-59-6. Pack Sizes: 5 g; 10 g. Product ID: HY-W002404.
Pyrimidine-4-carboxylic acid ≥95% (NMR)
Pyrimidine-4-carboxylic acid ≥95% (NMR). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
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Pyrimidine-4-carboxylic acid hydrazide
Pyrimidine-4-carboxylic acid hydrazide. Group: Biochemicals. Alternative Names: 4-Pyrimidinecarboxylic acid hydrazide. Grades: Highly Purified. CAS No. 39513-54-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Pyrimidine-5-boronic acid pinacol ester is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 321724-19-0. Pack Sizes: 5 g; 10 g. Product ID: HY-42045.
Pyrimidine-5-carbothioic acid amide
Pyrimidine-5-carbothioic acid amide. Group: Biochemicals. Grades: Highly Purified. CAS No. 88891-75-2. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. US Biological Life Sciences.
Worldwide
Pyrimidine-5-carbothioic acid amide 99+%
Pyrimidine-5-carbothioic acid amide 99+%. Group: Biochemicals. Grades: Reagent Grade. CAS No. 88891-75-2. Pack Sizes: 100mg, 250mg, 1g. US Biological Life Sciences.
Heterocyclic Organic Compound. CAS No. 114969-98-1. Catalog: ACM114969981.
pyrimidine-5'-nucleotide nucleosidase
Also acts on dUMP, dTMP and dCMP. Group: Enzymes. Synonyms: pyrimidine nucleotide N-ribosidase; Pyr5N. Enzyme Commission Number: EC 3.2.2.10. CAS No. 9023-31-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3964; pyrimidine-5'-nucleotide nucleosidase; EC 3.2.2.10; 9023-31-8; pyrimidine nucleotide N-ribosidase; Pyr5N. Cat No: EXWM-3964.
Pyrimidinecarboxaldehyde
Pyrimidinecarboxaldehyde. CAS No: 90905-62-7
Sarchem Laboratories New Jersey NJ
pyrimidine-deoxynucleoside 1'-dioxygenase
Requires Fe(II) and ascorbate. cf. EC 1.14.11.3, pyrimidine-deoxynucleoside 2'-dioxygenase. Group: Enzymes. Synonyms: deoxyuridine-uridine 1'-dioxygenase. Enzyme Commission Number: EC 1.14.11.10. CAS No. 98865-52-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0626; pyrimidine-deoxynucleoside 1'-dioxygenase; EC 1.14.11.10; 98865-52-2; deoxyuridine-uridine 1'-dioxygenase. Cat No: EXWM-0626.
pyrimidine-deoxynucleoside 2'-dioxygenase
Requires Fe(II) and ascorbate. Also acts on thymidine. cf. EC 1.14.11.10, pyrimidine-deoxynucleoside 1'-dioxygenase. Group: Enzymes. Synonyms: deoxyuridine 2'-dioxygenase; deoxyuridine 2'-hydroxylase; pyrimidine deoxyribonucleoside 2'-hydroxylase; thymidine 2'-dioxygenase; thymidine 2'-hydroxylase; thymidine 2-oxoglutarate dioxygenase; thymidine dioxygenase. Enzyme Commission Number: EC 1.14.11.3. CAS No. 9076-89-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0647; pyrimidine-deoxynucleoside 2'-dioxygenase; EC 1.14.11.3; 9076-89-5; deoxyuridine 2'-dioxygenase; deoxyuridine 2'-hydroxylase; pyrimidine deoxyribonucleoside 2'-hydroxylase; thymidine 2'-dioxygenase; thymidine 2'-hydroxylase; thymidine 2-oxoglutarate dioxygenase; thymidine dioxygenase. Cat No: EXWM-0647.
pyrimidine-nucleoside phosphorylase
Unlike EC 2.4.2.3, uridine phosphorylase, and EC 2.4.2.4, thymidine phosphorylase, this enzyme can accept both the ribonucleoside uridine and the 2'-deoxyribonucleosides 2'-deoxyuridine and thymidine. The reaction is reversible, and the enzyme does not distinguish between α-D-ribose 1-phosphate and 2-deoxy-α-D-ribose 1-phosphate in the synthetic direction. Group: Enzymes. Synonyms: Py-NPase; pdp (gene name). Enzyme Commission Number: EC 2.4.2.2. CAS No. 9055-35-0. PyNPase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2647; pyrimidine-nucleoside phosphorylase; EC 2.4.2.2; 9055-35-0; Py-NPase; pdp (gene name). Cat No: EXWM-2647.
Pyrimidine nucleoside phosphorylase, Recombinant
Pyrimidine nucleoside phosphorylase (PyNPase) is a glycosyltransferase that catalyzes the conversion of pyrimidine nucleoside and phosphate to a pyrimidine base and α-D-ribose 1-phosphate. PyNPase plays a significant role in breast cancer angiogenesis. Applications: Pyrimidine nucleoside phosphorylase (pynpase) may be used as a marker to predict the malignant potential of breast cancer, especially lymph node metastasis. pynpase is used to study breast cancer, specifically its role in angiogenesis. Group: Enzymes. Synonyms: Pyrimidine nucleoside phosphorylase; EC 2.4.2.2; Py-NPase; 9055-35-0; pdp (gene name); PyNPase. Enzyme Commission Number: EC 2.4.2.2. CAS No. 9055-35-0. PyNPase. Activity: > 1300 U/mL. Storage: -20°C. Source: E. coli. Pyrimidine nucleoside phosphorylase; EC 2.4.2.2; Py-NPase; 9055-35-0; pdp (gene name); PyNPase. Cat No: NATE-0646.
pyrimidine oxygenase
In vitro the product (Z)-3-ureidoacrylate peracid is spontaneously reduced to ureidoacrylate. Part of the Rut pyrimidine catabolic pathway. Group: Enzymes. Synonyms: RutA. Enzyme Commission Number: EC 1.14.99.46. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1056; pyrimidine oxygenase; EC 1.14.99.46; RutA. Cat No: EXWM-1056.
Pyrimidine Related Compound 1
An impuritiy of Pyrimethamine.Pyrimethamine can be used with leucovorin to treat toxoplasmosis and cystoisosporiasis. It is also used with dapsone as a second line option to prevent Pneumocystis jiroveci pneumonia in people with HIV/AIDS. Synonyms: 2-Chloro-N, N-diethyl-5-[[4-[2-[4-[[ (methylamino)carbonyl]amino]phenyl]-4-pyridinyl]-2-pyrimidinyl]amino]benzenesulfonamide. Grades: > 95%. CAS No. 1402452-15-6. Molecular formula: C27H28ClN7O3S. Mole weight: 566.09.
1,2,3,4,5,6,7,8-Octahydro-2,4-dioxo-[1]benzothieno[2,3-d]pyrimidine-5-carboxylic Acid is used in the synthesis of imidazo[1,2-a]thienopyrimidin-2-one derivatives as blood platelet aggregation inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 1417635-86-9. Pack Sizes: 10mg, 100mg. Molecular Formula: C11H10N2O4S, Molecular Weight: 266.27. US Biological Life Sciences.
An impurity of Nifedipine, which is a dihydropyridine calcium channel blocker that primarily blocks L-type calcium channels. Synonyms: Methyl 1,2,3,4-tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylate. CAS No. 108139-78-2. Molecular formula: C19H18N4O6. Mole weight: 398.37.
1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester-d3. (Mixture of Diastereomers)
1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester-d3 is the isotope labelled analog of 1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester (T295600); an impurity of Nifedipine (N457000) which is a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 50mg. Molecular Formula: C19H15D3N4O6, Molecular Weight: 401.39. US Biological Life Sciences.
1-(2,6-Difluorobenzyl)-5-[(dimethylamino)methyl]-3-(6-methoxypyridazine-3-yl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione is an impurity of Relugolix, which is an orally administered gonadotropin-releasing hormone (GnRH) receptor antagonist used in the treatment of several hormone-responsive conditions, including uterine fibroids, advanced prostate cancer, and endometriosis. Synonyms: Thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione, 1-[(2,6-difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-nitrophenyl)-; 1-[(2,6-Difluorophenyl)methyl]-5-[(dimethylamino)methyl]-3-(6-methoxy-3-pyridazinyl)-6-(4-nitrophenyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione; Relugolix Impurity 9. Grades: ≥95%. CAS No. 1589503-96-7. Molecular formula: C27H22F2N6O5S. Mole weight: 580.56.
1-((2R,3R,4R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a chemical compound of potential interest in biomedical research, has been studied for its therapeutic benefits against various diseases. Research shows promising antiviral properties against viral infections such as HIV and the capacity to inhibit cancer cell proliferation enzymes, making it a potential candidate for cancer treatment. However, further investigation is necessary to comprehend its full range of therapeutic uses. Synonyms: 1-((2R,3R,4R)-4-((tert-butyldimethylsilyl)oxy)-3-fluoro-5,5-bis(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-[(2R,3R,4R)-4-[tert-butyl(dimethyl)silyl]oxy-3-fluoro-5,5-bis(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione; C16H27FN2O6Si; DTXSID101126509; CS-M3506; VHC37961; AKOS037650615; CS-15069; C13027; 2'-Deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-2'-fluoro-4'-C-(hydroxymethyl)uridine. Grades: 98%. CAS No. 1445379-61-2. Molecular formula: C16H27FN2O6Si. Mole weight: 390.48.
1-((2R,3R,4R,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione, a powerful antimicrobial agent, is renowned for its efficacy in treating a range of bacterial and fungal infections, including those caused by Candida, Aspergillus, and Cryptococcus species. This pharmaceutical marvel works by clobbering the synthesis of crucial nucleic acids in microbes to sabotage their survival. Notably, its phenomenal antibacterial and antifungal activity renders it an essential tool in the battle against streptococcal and staphylococcal infections. Synonyms: Sofosbuvir impurity SA15432. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-((2R,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is an efficacious pharmaceutical compound that has been extensively studied to treat viral infections caused by herpes simplex virus (HSV), varicella-zoster virus (VZV), and cytomegalovirus (CMV). The remarkable feature of this drug is its ability to effectively inhibit viral DNA polymerase, thereby halting viral replication and preventing spread. As nucleoside analogue, it is a preferred choice for combination therapy to achieve superior antiviral potency. The exquisite chemical structure of this compound enables it to bind to the viral polymerase in a unique manner, conferring its remarkable therapeutic benefit. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1-((2R,4aR,7R,8S,8aS)-8-Hydroxy-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-7-yl)pyrimidine-2,4(1H,3H)-dione is a promising therapeutic agent that is yet to gain approval from the FDA. This potential drug candidate has been reported to have beneficial effects in mitigating neurodegenerative disorders like Alzheimer's and Parkinson's disease through efficient amyloid beta and alpha-synuclein proteins aggregation inhibition. Synonyms: 2-(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)-1,5-anhydro-2-deoxy-4,6-O-[(R)-phenylmethylene]-D-altritol. CAS No. 401906-98-7. Molecular formula: C17H18N2O6. Mole weight: 346.33.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione, a small molecule inhibitor, possesses remarkable potency against various cancer types. Its mechanism of action involves targeting proteins essential for cancer cell growth and replication, promoting tumor shrinkage and cell death. As demonstrated in lung, breast, colon, and ovarian cancer, it exhibits impressive antitumor activity, embodying a promising candidate for cancer therapy. Synonyms: Morpholino thymidine; 1-((2R,6S)-6-(hydroxymethyl)morpholin-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-5-methyl-2,4(1H,3H)-pyrimidinedione; YML1Y6H5HD; 1-[(2R,6S)-6-(hydroxymethyl)morpholin-2-yl]-5-methylpyrimidine-2,4-dione; 1-((2R,6S)-6-(Hydroxymethyl)-2-morpholinyl)-5-methyl-2,4(1H,3H)-pyrimidinedione; 1-(6-Hydroxymethyl-morpholin-2-yl)-5-methyl-1H-pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrimidinedione, 1-((2R,6S)-6-(hydroxymethyl)-2-morpholinyl)-5-methyl-; UNII-YML1Y6H5HD; SCHEMBL24420143; CS-0100784; A897935. CAS No. 179073-10-0. Molecular formula: C10H15N3O4. Mole weight: 241.24.
1-((2R,6S)-6-(Hydroxymethyl)morpholin-2-yl)pyrimidine-2,4(1H,3H)-dione, a critically important pharmaceutical component, serves as a fundamental precursor in synthesizing a spectrum of lifesaving medications, crucially employed in combating ailments like cancer, inflammation, and viral infections across varied biological settings and therapeutic contexts. Synonyms: 1-[(2R,6S)-6-(Hydroxymethyl)-2-morpholinyl]-2,4(1H,3H)-pyrimidinedione. Grades: 97%. CAS No. 109205-43-8. Molecular formula: C9H13N3O4. Mole weight: 227.22.
1-((2S,3S,4S,5R)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione is a powerful tool in the biomedical industry, indicated for cancer, HIV and hepatitis B treatment. Its multifunctional activity includes antiviral, antitumor, and anti-inflammatory effects, with early evidence supporting a potentially revolutionary capacity as a cancer stem cell targeting therapeutic agent. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
1,4-Dihydro-1-[2-(2-methoxyphenyl)-2-[(tetrahydro-2H-pyran-4-yl)oxy]ethyl]-α,α-dimethyl-6-(2-oxazolyl)-2,4-dioxothieno[3,2-d]pyrimidine-3(2H)-acetic Acid is a compound that can be synthesized from 3-Amino-2-methoxycarbonyl thiophene (A612075), a useful synthetic intermediate. Group: Biochemicals. Grades: Highly Purified. CAS No. 1644743-68-9. Pack Sizes: 500ug, 2.5mg. Molecular Formula: C27H29N3O8S, Molecular Weight: 555.6. US Biological Life Sciences.
1,5,6,7-Tetrahydro-5-(phosphonomethyl)-imidazo[1,2-a]pyrimidine-2-carboxylic Acid was reported as a potential treatment of neurotoxic injury. Group: Biochemicals. Grades: Highly Purified. CAS No. 156610-89-8. Pack Sizes: 2.5mg, 5mg. Molecular Formula: C8H12N3O5P, Molecular Weight: 261.17. US Biological Life Sciences.
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