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Queuine is a hypermodified nucleobase , which is modified to queuosine. Queuine, as an important micronutrient, can be used for the research of diseases associated with human gut microbiome [1]. Uses: Scientific research. Group: Natural products. CAS No. 72496-59-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-N10574.
Queuine dihydrochloride
Queuine dihydrochloride is a super-modified nucleobase, modified to queuosine dihydrochloride. Queuine dihydrochloride is an important micronutrient that can be used in the study of human intestinal microbial-related diseases [1]. Uses: Scientific research. Group: Natural products. CAS No. 86496-18-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N10574A.
Queuine Hydrochloride
Cas No. 69565-92-0.
Queuine Hydrochloride
It is one of the modified base which is found at first anticodon position of specific tRNAs. Group: Biochemicals. Alternative Names: 2-Amino-5-[[[(1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl]amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Dihydrochloride; [1S-(1α,4 β,5 β)]-2-Amino-5-[[(4,5-dihydroxy-2-cyclopenten-1-yl)amino]methyl]-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one Hydrochloride. Grades: Highly Purified. CAS No. 69565-92-0. Pack Sizes: 500ug. Molecular Formula: C??H??N?O?.(ClH)?, Molecular Weight: 277.28. US Biological Life Sciences.
(3aS,6R,6aR)-Dihydro-6-methoxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4(3aH)-one is an intermediate in the synthesis of Queuine, the modified base which is found at first anticodon position of specific tRNAs. Synonyms: 2,3-Isopropyl-ribose-1-O-Methy-4-lactone; [3aS-(3aα,6α,6aα)]-Dihydro-6-methoxy-2,2-dimethylfuro[3,4-d]-1,3-dioxol-4(3aH)-one; Furo[3,4-d]-1,3-dioxol-4(3aH)-one, dihydro-6-methoxy-2,2-dimethyl-, (3aS,6R,6aR)-. Grades: ≥95% by HPLC. CAS No. 125851-01-6. Molecular formula: C8H12O5. Mole weight: 188.18.
preQ1 dihydrochloride
preQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine (HY-N10574) biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 86694-45-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115642.
preQ1 synthase
The reaction occurs in the reverse direction. This enzyme catalyses one of the early steps in the synthesis of queuosine (Q-tRNA), and is followed by the action of EC 2.4.2.29, queuine tRNA-ribosyltransferase. Queuosine is found in the wobble position of tRNAGUN in Eukarya and Bacteria and is thought to be involved in translational modulation. The enzyme is not a GTP cyclohydrolase, as was thought previously based on sequence-homology studies. Group: Enzymes. Synonyms: YkvM; QueF; preQ0 reductase; preQ0 oxidoreductase; 7-cyano-7-deazaguanine reductase; queuine synthase (incorrect as queuine is not the product); queuine:NADP+ oxidoreductase (incorrect as queuine is not the product). Enzyme Commission Number: EC 1.7.1.13. CAS No. 1256460-80-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1606; preQ1 synthase; EC 1.7.1.13; 1256460-80-6; YkvM; QueF; preQ0 reductase; preQ0 oxidoreductase; 7-cyano-7-deazaguanine reductase; queuine synthase (incorrect as queuine is not the product); queuine:NADP+ oxidoreductase (incorrect as queuine is not the product). Cat No: EXWM-1606.
tRNA-guanosine34 transglycosylase
Certain prokaryotic and eukaryotic tRNAs contain the modified base queuine at position 34. In eukaryotes queuine is salvaged from food and incorporated into tRNA directly via a base-exchange reaction, replacing guanine. In eubacteria, which produce queuine de novo, the enzyme catalyses the exchange of guanine with the queuine precursor preQ1, which is ultimately modified to queuosine. The eubacterial enzyme can also use an earlier intermediate, preQ0, to replace guanine in unmodified tRNATyr and tRNAAsn. This enzyme acts after EC 1.7.1.13, preQ1 synthase, in the queuine-biosynthesis pathway. Group: Enzymes. Synonyms: guanine insertion enzyme (ambiguous); tRNA transglycosylase (ambiguou. Enzyme Commission Number: EC 2.4.2.29. CAS No. 72162-89-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2656; tRNA-guanosine34 transglycosylase; EC 2.4.2.29; 72162-89-1; guanine insertion enzyme (ambiguous); tRNA transglycosylase (ambiguous); Q-insertase (ambiguous); queuine34 transfer ribonucleate ribosyltransferase; transfer ribonucleate glycosyltransferase (ambiguous); tRNA guanine34 transglycosidase; queuine tRNA-ribosyltransferase (ambiguous); TGT; [tRNA]-guanine34:queuine tRNA-D-ribosyltransferase; transfer ribonucleic acid guanine34 transglycosylase. Cat No: EXWM-2656.
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