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Quinacrine hydrochloride Quinacrine dihydrochloride is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities. Quinacrine may inhibit the transcription and activity of both basal and inducible nuclear factor-kappaB (NF-kappaB), which may result in the induction of tumor suppressor p53 transcription, the restoration of p53-dependent apoptotic pathways, and tumor cell apoptosis. Continuous NF-kappaB signaling, present in many tumors and in chronic inflammatory processes, promotes the expression of antiapoptotic proteins and cytokines while downregulating the expression of proapoptotic proteins, such as p53. Synonyms: atabrine dihydrochloride; mepacrine dihydrochoride; SN 390. CAS No. 69-05-6. Molecular formula: C23H30ClN3O.2HCl. Mole weight: 472.88. BOC Sciences
Quinacrine hydrochloride hydrate Quinacrine hydrochloride hydrate (Mepacrine hydrochloride hydrate) is an antimalarial agent, which possess anticancer effect both in vitro and vivo. Quinacrine hydrochloride hydrate suppresses NF-κB and activates p53 signaling, which results in the induction of the apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mepacrine hydrochloride hydrate; SN-390 hydrochloride hydrate. CAS No. 6151-30-0. Pack Sizes: 100 mg. Product ID: HY-13735B. MedChemExpress MCE
Mepenzolate Bromide analytical standard. Group: Additional drugsapi standardspharmaceutical toxicology. Alternative Names: Chemiochin, 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, dihydrochloride (9CI), 2-Chloro-5-(?-diethylamino-?-methylbutylamino)-7-methoxyacridine dihydrochloride, Atebrine, Crinodora, Mecryl, Pentilen, Methoquine, Acrichin dihydrochloride, Atabrine hydrochloride, 6-Chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxyacridine dihydrochloride, Quinacrine hydrochloride, 866RP, Metochin, 3-Chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine dihydrochloride, Erion, 3-Chloro-9-(4'-diethylamino-1'-methylbutylamino)-7-methoxyacridine dihydrochloride, Mepacrine hydrochloride, Quinacrine dihydrochloride,Mepacrine Hydrochloride, Atebrine hydrochloride, Metoquin, Palusan, Palacrin, 1,4-Pentanediamine, N4-(6-chloro-2-methoxy-9-acridinyl)-N1,N1-diethyl-, hydrochloride (1:2), 2-Methoxy-6-chloro-9-(4-diethylamino-1-methylbutylamino)acridine dihydrochloride, Chinacrin hydrochloride, Malaricida, NSC 14229, Mepacrine dihydrochloride, Metoquine, Atebrin, SN 390, Acridine, 6-chloro-9-[[4-(diethylamino)-1-methylbutyl]amino]-2-methoxy-, dihydrochloride (8CI). Alfa Chemistry Analytical Products 4

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