Receptor Suppliers USA
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Product | Description | |
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Receptor-type tyrosine-protein kinase FLT3 (591-600) Quick inquiry Where to buy Suppliers range | Receptor-type tyrosine-protein kinase FLT3. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-204. | |
Receptor-type tyrosine-protein kinase FLT3 (591-600) Quick inquiry Where to buy Suppliers range | Receptor-type tyrosine-protein kinase FLT3 (591-600) is a truncated fragment of Receptor-type tyrosine-protein kinase FLT3. Tyrosine-protein kinase acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Synonyms: FL cytokine receptor (591-600); Fetal liver kinase-2 (591-600); Fms-like tyrosine kinase 3 (591-600). | |
Receptor-type tyrosine-protein phosphatase kappa (667-682) Quick inquiry Where to buy Suppliers range | A peptide fragment of Receptor-type tyrosine-protein phosphatase kappa. Receptor-type tyrosine-protein phosphatase kappa is in the regulation of processes involving cell contact and adhesion such as growth control, tumor invasion, and metastasis. Synonyms: Protein-tyrosine phosphatase kappa (667-682). | |
Receptor-type tyrosine-protein phosphatase kappa (667-682) Quick inquiry Where to buy Suppliers range | Receptor-type tyrosine-protein phosphatase kappa. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-231. | |
Receptor tyrosine-protein kinase erbB-2 (1023-1032) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-339. | |
Receptor tyrosine-protein kinase erbB-2 (369-377) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-331. | |
Receptor tyrosine-protein kinase erbB-2 (391-399) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-340. | |
Receptor tyrosine-protein kinase erbB-2 (402-410) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-341. | |
Receptor tyrosine-protein kinase erbB-2 (435-443) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-334. | |
Receptor tyrosine-protein kinase erbB-2 (466-474) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-342. | |
Receptor tyrosine-protein kinase erbB-2 (48-56) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-338. | |
Receptor tyrosine-protein kinase erbB-2 (5-13) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-333. | |
Receptor tyrosine-protein kinase erbB-2 (63-71) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-345. | |
Receptor tyrosine-protein kinase erbB-2 (650-658) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-343. | |
Receptor tyrosine-protein kinase erbB-2 (654-662) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-332. | |
Receptor tyrosine-protein kinase erbB-2 (665-673) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-336. | |
Receptor tyrosine-protein kinase erbB-2 (689-697) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-335. | |
Receptor tyrosine-protein kinase erbB-2 (754-762) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-344. | |
Receptor tyrosine-protein kinase erbB-2 (952-961) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-337. | |
Receptor tyrosine-protein kinase erbB-2 precursor (369-386) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2, is a protein that in humans is encoded by the ERBB2 gene. Amplification or over-expression of this oncogene has been shown to play an important role in the development and progression of certain aggressive types of breast cancer. In recent years the protein has become an important biomarker and target of therapy for approximately 30% of breast cancer patients. Synonyms: CD340 precursor (369-386). | |
Receptor tyrosine-protein kinase erbB-2 precursor (369-386) Quick inquiry Where to buy Suppliers range | Receptor tyrosine-protein kinase erbB-2. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-089. | |
TGR5 Receptor Agonist, Cpd23g ( (4-cyclopropyl-3, 4-dihydroquinoxalin-1 (2H) -yl) (4- (2, 5-dimethylphenoxy) pyridin-3-yl) methanone, Bile Acid Receptor GPBAR-1 Agonist, Bile Acid Receptor Agonist, G Protein-coupled Bile Acid Receptor 1 Agonist) Quick inquiry Where to buy Suppliers range | A cell-permeable, orally available, phenoxypyrimidine carboxamide derivative that acts as a highly potent and selective agonist of Protein coupled receptor TGR5 (EC50 = 720 pM and 6.2nM for human and mouse TGR5, respectively). Does not exhibit any significant affinity towards other related targets such as GPR40, GPR119, and GPR120. Shown to increase glucagon-like peptide-1 (GLP-1) secretion in a dose-dependent manner and significantly reduce blood glucose levels in db/db mice following a single oral dose (50mg/kg). Exhibits desirable pharmacokinetic properties in rodent models (t½ = 1.5h, Cmax = 56ng/ml; and AUC = 147ng.h/ml following an oral dose of 5mg/kg). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Opioid Receptor, delta Control Peptide (OPRD1, Opioid Receptor delta, Delta-type Opioid Receptor, DOR-1, OPRD) Quick inquiry Where to buy Suppliers range | Opioid Receptor, delta Control Peptide (OPRD1, Opioid Receptor delta, Delta-type Opioid Receptor, DOR-1, OPRD). Group: Molecular Biology. Grades: Purified. Pack Sizes: 150nmole. US Biological Life Sciences. | Worldwide |
Oxidized ATP (oATP, Purinergic Receptor Antagonist, Oxidized ATP, Purinergic Receptor P2X7 Antagonist, Oxidized ATP, Purinergic Receptor Inhibitor, Oxidized ATP, O-ATP) Quick inquiry Where to buy Suppliers range | A 2,3-dialdehyde derivative of ATP that is commonly used to affinity label nucleotide sites in enzymes. Acts as a specific, irreversible antagonist of P2Z/P2X7 purinergic receptors in J774 mouse macrophages. Does not affect P2g receptors. Inhibits inflammatory pain in arthritic rat model by blocking ATP action on P2X7 receptor in nerve terminals. Also shown to irreversibly block ATP-induced Ca2+ influx in lymphocytes (100uM). O-ATP-treated mice display better preservation and lower rate of rejection of pancreatic islet grafts with reduced Th1 transcripts. Group: Biochemicals. Grades: Highly Purified. CAS No. 71997-40-5. Pack Sizes: 25mg. Molecular Formula: C??H??N?O??P?. US Biological Life Sciences. | Worldwide |
A317491 ((S)-5-((3-phenoxybenzyl)(1,2,3,4-tetrahydronaphthalen-1-yl)carbamoyl)benzene-1,2,4-tricarboxylic Acid, P2X3 Purinergic Receptors Antagonist, A317491, P2X2/3 Purinergic Receptors Antagonist, A317491, A 317491) Quick inquiry Where to buy Suppliers range | A potent, selective, and competitive non-nucleotide antagonist of P2X3 and P2X2/3 receptors that blocks receptor-mediated Ca2+ flux (Ki = 22 and 92nM for rat P2X3 and P2X2/3 receptor and 22 and 9nM for human P2X3 and P2X2/3 receptor, respectively). Its R-enantiomer has significantly reduced activity at these receptors. Exhibits high selectivity over other purinergic receptors. Shown to reduce thermal and mechanical hyperalgesia in rat models (ED50 = 10-15uM/kg, s.c). Its anti-nociceptive effects have a rapid on-set and persist for up to 5 hours after sub-cutaneous administration. Also shown to block dorsal root ganglion currents in a dose-dependent manner (IC50 = 15nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 475205-49-3. Pack Sizes: 5mg. Molecular Formula: C??H??NO? xH2O xNa. US Biological Life Sciences. | Worldwide |
AF353 (P2X3 Purinergic Receptor Antagonist, AF353, P2X2/3 Purinergic Receptor Antagonist, AF353) Quick inquiry Where to buy Suppliers range | A novel, potent, orally bioavailable antagonist of P2X3/P2X2/3 receptors (pIC50 = 8 in human and rat; pIC50 = 7.3 for human P2X2/3 receptor). Shown to be highly brain penetrant with a brain to plasma ratio of 6. Blocks agonist-evoked intracellular Ca2+ flux and inward currents in nanomolar range (10nM to 1uM) in cell lines recombinantly expressing human P2X3 and P2X2/3 receptors. Exhibits desirable pharmacokinetic properties (t1/2 = 1.63 h and Tmax = 30 min). Group: Biochemicals. Grades: Highly Purified. CAS No. 927887-18-1. Pack Sizes: 5mg. Molecular Formula: C??H??ClIN?O?. US Biological Life Sciences. | Worldwide |
(+/-)-Atenolol ( (±) -4- {2-Hydroxy-3- [ (1-methylethyl) amino] propoxy} benzeneacetamide, Beta1-Adrenergic Receptor Blocker, (±)-Atenolol, Beta1-Adrenergic Receptor Antagonist, (±)-Atenolol) Quick inquiry Where to buy Suppliers range | Selective beta-1 adrenergic blocking agent. An anti-hypertensive and anti-arrhythmic agent. Reported to diminish cerebrospinal fluid production. Group: Biochemicals. Grades: Highly Purified. CAS No. 29122-68-7. Pack Sizes: 1g. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
BzATP Triethylammonium Salt (2 (3) -O- (4-Benzoylbenzoyl) adenosine-5-triphosphate tri(triethylammonium) Salt, P2X7 Purinergic Receptor Agonist, BZATP, 2 ,3 -O-(4-benzoylbenzoyl)ATP, P2X Purinergic Receptor Agonist, BZATP) Quick inquiry Where to buy Suppliers range | A prototypic P2X7 purinergic receptor agonist that exhibits about 3-fold higher agonistic potency for induction of nucleotide channels than ATP (EC50 = 15uM vs 50uM). Serves as a photo-affinity analog of ATP. Its agonistic activity is significantly reduced in the presence of serum albumin. Can serve as a substrate analog for submitochondrial particle ATPase activity (Km = 940uM). Induces a dose-dependent decrease in wild-type murine neural progenitor cell viability and an increase in caspase-3 activity. These effects are not observed in P2X7-/- mice. Group: Biochemicals. Grades: Highly Purified. CAS No. 112898-15-4. Pack Sizes: 1mg. Molecular Formula: C??H??N?O??P? 3C?H??N. US Biological Life Sciences. | Worldwide |
c-Met, Phosphotyrosine1003, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR) Quick inquiry Where to buy Suppliers range | c-Met, Phosphotyrosine1003, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
c-Met, Phosphotyrosine1003, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR) Quick inquiry Where to buy Suppliers range | c-Met, Phosphotyrosine1003, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFRR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
c-Met pYpYpY1230/1234/1235, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) Quick inquiry Where to buy Suppliers range | c-Met pYpYpY1230/1234/1235, Negative Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR) Quick inquiry Where to buy Suppliers range | c-Met pYpYpY1230/1234/1235, Positive Control Peptide (Hepatocyte Growth Factor Receptor, Scatter Factor Receptor, HGFR, SFR). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
DNQX Disodium Salt (AMPA Glutamate Receptor Antagonist, DNQX, Kainate Glutamate Receptor Antagonist, DNQX) Quick inquiry Where to buy Suppliers range | A potent competitive antagonist selective for AMPA/kainate glutamate receptors (IC50 = 0.19-1.66uM and 0.35uM for AMPA and GluK2 receptors, respectively). Routinely used as a tool to distinguish the role of neurotransmissions mediated by AMPA/kainate andnMDA receptors in studying brain functions and disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 2379-57-9. Pack Sizes: 10mg. Molecular Formula: C?H?N?O?Na?, Primary Target: AMPA. US Biological Life Sciences. | Worldwide |
Glucagon-Like Peptide 1 Receptor Agonist II (4- (3- (benzyloxy) phenyl) -2- (ethylsulfinyl) -6- (trifluoromethyl) pyrimidine, Glucagon-Like Peptide 1 Receptor Agonist II, Compound B) Quick inquiry Where to buy Suppliers range | A pyrimidine small molecule that acts as a GLP-1 allosteric agonist that induces cAMP signaling in HEK293 cells expressing the GLP-1 receptor with EC50 = 0.66uM and 99% efficacy (similar data with rat GLP-1 receptor), does not compete with radiolabelled GLP-1 in receptor binding assays, and is not active in cells expressing the GLP-2, GIP, PTH, or glucagon receptors. In rodent islets, insulin secretion increases in a dose-dependent and glucose-dependent manner, either alone or in an additive fashion when combined with the endogenous GLP-1 peptide. In vivo, this molecule exhibits insulinotropic effects when dosed at 10mg/kg in SD rats undergoing an IVGTT and a hyperglycemic clamp. It is also shown to increase insulin secretion in perifusion assays involving normal and diabetic human islets ex vivo, at concentrations between 1 and 10uM. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Muscarinic Receptor M4 Control Peptide (Cholinergic Muscarinic Receptor M4, Chrm4) Quick inquiry Where to buy Suppliers range | Muscarinic Receptor M4 Control Peptide (Cholinergic Muscarinic Receptor M4, Chrm4). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 150nmole. US Biological Life Sciences. | Worldwide |
Muscarinic Receptor M5, Control Peptide (Cholinergic Muscarinic Receptor M5, Chrm5) Quick inquiry Where to buy Suppliers range | Muscarinic Receptor M5, Control Peptide (Cholinergic Muscarinic Receptor M5, Chrm5). Group: Molecular Biology. Grades: Highly Purified. Pack Sizes: 150nm. US Biological Life Sciences. | Worldwide |
Pramipexole Dihydrochloride (Pramipexole, Dopamine D2-like Receptor Agonist, Pramipexole, Dopamine D3 Receptor Agonist, Pramipexole, (S) -N-propyl -4, 5, 6, 7-tetra hydrobenzothiazole-2, 6-diamine Dihydrochloride) Quick inquiry Where to buy Suppliers range | Non-ergot Dopamine receptor agonist with selectivity for the D3 receptor (Ki values are 0.5, 3.3, 3.9 and 3.9nM for D3, D2S, D2L and D4 receptors respectively). Exhibits very low affinity for serotoninergic 5-HT2A and 5-HT2B receptors, as well as D1-type receptors. Shows good solubility in aqueous media (100mM water and 100mM DMSO). Immediate-release (IR) pramipexole dihydrochloride is indicated for the treatment of signs and symptoms of idiopathic Parkinsons disease (PD). It is administered alone (without levodopa) or in combination with levodopa, during the entire progress of the disease, up to an advanced stage. Currently, it is also indicated for the treatment of moderate-to-severe primary restless legs syndrome (RLS). Group: Biochemicals. Grades: Highly Purified. CAS No. 104632-25-9. Pack Sizes: 10mg. Molecular Formula: C??H??N?S 2HCl. US Biological Life Sciences. | Worldwide |
SB 206553 Hydrochloride (5-HT2C Serotonin Receptor Antagonist, SB 206553, 5-HT2B Serotonin Receptor Antagonist, SB 206553, SB206553, SB-206553) Quick inquiry Where to buy Suppliers range | A selective 5-HT2C serotonin receptor inhibitor with lesser affinity for 5-HT2BR. Often used in conjunction with ketanserin to distinguish 5-HT2AR and 5-HT2CR activity. SB206553 has highest affinity for 5-HT2CR (Ki = 3.2nM) and less for 5-HT2BR (Ki = 5.5nM) and 5-HT2AR (Ki = 2,300nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 158942-04-2. Pack Sizes: 10mg. Molecular Formula: C??H??N?O·HCl. US Biological Life Sciences. | Worldwide |
2,3 cis-Piperidine Dicarboxylic Acid (Ionotropic Glutamate Receptor Antagonist, PDA, cis PDA, cis-Piperidine-2,3-dicarboxylic Acid) Quick inquiry Where to buy Suppliers range | A non-specific antagonist of NMDA, AMPA and kainate ionotropic receptors and a partial agonist for NMDA receptors. Used in blocking general excitatory synaptic transmissions. Group: Biochemicals. Grades: Highly Purified. CAS No. 46026-75-9. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
(2S,4R)-4-methylglutamate (Kainate Receptor Agonsit, (2S,4R)-4-methylglutamate, SYM 2081) Quick inquiry Where to buy Suppliers range | A potent agonist highly selective for kainate receptors over AMPA receptors (EC50 = 0.06-0.38uM and 132-453uM for kainate and AMPA receptors, respectively). Useful for distinguishing the functional roles played by kainate and AMPA receptors in neurotransmissions. Group: Biochemicals. Grades: Highly Purified. CAS No. 31137-74-3. Pack Sizes: 1mg. Molecular Formula: C?H??NO?. US Biological Life Sciences. | Worldwide |
5-Iodo-A-85380 Dihydrochloride Hydrate (3-((2S)-2-Azetidinylmethoxy)-5-iodo-pyridine Dihydrochloride Hydrate, a4b2 and a6b2 Nicotinic Acetylcholine Receptors (nAChR) Agonist, 5-Iodo-A-85380) Quick inquiry Where to buy Suppliers range | A very potent agonist highly selective for alpha4beta2 and alpha6beta2 nicotinic acetylcholine receptors (nAChR) (Ki= 12 and 10 pM for human and rat alpha4beta2 nAChRs, respectively). An important nAChR ligand for the treatment of pain, smoking addition and other mental disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 213550-82-4. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
A2B receptor antagonist 1 Quick inquiry Where to buy Suppliers range | A potent antagonist of A2B adenosine receptor. Synonyms: 1H-Purine-2,6-dione, 3,9-dihydro-8-[1-(phenylmethyl)-1H-pyrazol-4-yl]-1,3-dipropyl-. CAS No. 531506-36-2. Molecular formula: C21H24N6O2. Mole weight: 392.45. | |
A740003 (N-(1-{[(cyanoimino)(5-quinolinylamino) methyl] amino}-2, 2-dimethylpropyl) -2- (3, 4-dimethoxyphenyl) acetamide, A 740003, P2X7 Purinegic Receptor, A740003, A740003) Quick inquiry Where to buy Suppliers range | A highly potent, selective, competitive antagonist of P2X7 purinegic receptor (IC50 = 18nM and 40nM, respectively as measured by Bz-ATP-stimulated Ca2+ flux). Does not affect other P2 receptors even at 10uM concentrations. Blocks agonist-evoked IL-1b release (IC50 = 156nM) and pore formation (IC50 = 92nM) in differentiated human THP-1 cells. Also shown to reduce carrageenan and Freund's adjuvant -induced thermal hyperalgesia (ED50 = 38-54mg/kg, i.p) and neuropathic pain induced by chronic constriction injury (CIC) of the sciatic nerve. Group: Biochemicals. Grades: Highly Purified. CAS No. 861393-28-4. Pack Sizes: 5mg. Molecular Formula: C??H??N?O?, Primary Target: P2X7. US Biological Life Sciences. | Worldwide |
Adenosine A1 Receptor Agonist I, CPA ( (2R, 3R, 4S, 5R) -2- (6- (cyclopentylamino) -9H-purin-9-yl) -5- (hydroxymethyl) tetrahydrofuran-3, 4-diol, N6-Cyclopentyl-adenosine) Quick inquiry Where to buy Suppliers range | A potent and selective agonist of adenosine A1 receptor (A1R) (Ki = 2.3nM, 790nM, 18.6uM, 43nM for human A1, A2A, A2B, and A3, respectively). Group: Biochemicals. Grades: Highly Purified. CAS No. 41552-82-3. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
Adenosine A1 Receptor Agonist II, CCPA ( (2R, 3R, 4S, 5R) -2- (2-chloro-6- (cyclopentylamino) -9H-purin-9-yl) -5- (hydroxymethyl) tetrahydrofuran-3, 4-diol, 2-Chloro-N6-cyclopentyladenosine) Quick inquiry Where to buy Suppliers range | An adenosine analog that acts as a selective, high affinity agonist for Adenosine A1 receptor (A1R) (Ki = 800 pM; 2.3uM, 18.8uM, and 42nM for human A1, A2A, A2B, A3 respectively). Shown to be centrally active following systemic administration and exhibits anti-convulsive effects. Also reported to inhibit adenylate cyclase activity in rat fat cell membrane (IC50 = 33nM). Diminishes respiratory rhythm, reduces heart rate, and enhances the activity of KATP channels. Reduces norepinephrine release by about 50% in untreated and pertussis toxin treated hearts.CAS Number:37739-05-2. Group: Biochemicals. Grades: Highly Purified. CAS No. 37739-05-2. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O?. US Biological Life Sciences. | Worldwide |
Adenosine A1 Receptor Antagonist I, DPCPX (8-Cyclopentyl-1,3-dipropylxanthine, CPX, PD-116,948) Quick inquiry Where to buy Suppliers range | A blood-brain barrier permeable xanthine derivative that acts as a highly selective antagonist of Adenosine A1 receptor (A1R; Ki = 3.9nM, 130nM, 1.0uM, 4.0uM for human A1, A2A, A2B, and A3 respectively). Exhibits about 1,000-fold higher affinity and a 30-fold greater selectivity for A1R when compared to theophylline. Shown to competitively antagonize the inhibition of adenylate cyclase activity via A1 adenosine receptors in rat fat cells and the stimulation of adenylate cyclase via A2 adenosine receptors in human platelets. Exhibits hypertensive properties. Group: Biochemicals. Grades: Highly Purified. CAS No. 102146-07-6. Pack Sizes: 25mg. Molecular Formula: C??H??N?O?, Primary Target: A1. US Biological Life Sciences. | Worldwide |
Adenosine A2A/A1 Receptor Antagonist (2-Amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]-pyrimidin-5-one, diHCl) Quick inquiry Where to buy Suppliers range | A blood-brain barrier-permeant indenopyrimidinone that acts as a dual A1/A2A antagonist (Ki = 48.2 and 6.5nM, respectively, against agonist-induced cAMP response in A1- or A2A-expressing CHO-K1 cells) and effectively reverses D2 antagonist haloperidol- (1mg/kg; s.c.) induced catalepsy in both rats and mice (ED50 = 0.3 and <0.1mg/kg, respectively) in vivo by simultaneously reversing A1-mediated inhibition of DA (Dopamine) release and A2A-dependent inhibition of D2 receptor response to DA. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Adenosine A2A Receptor Agonist I, Hydrochloride (CGS 21680) Quick inquiry Where to buy Suppliers range | A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki = 27nM). Exhibits reduced affinity for A2B receptors (Ki = 67nM), but offers greater selectivity over A1R (Ki = 290nM) and A3R (88.8uM). Exerts an anti-inflammatory effect during chronic inflammation and ameliorates the tissue damage associated with collagen-induced arthritis. Also shown to reduce CCR7 Protein Expression in THP1 macrophages. Shown to delay the progressive deterioration of motor performance and prevent a reduction in brain weight in murine model of Huntington's disease. Group: Biochemicals. Alternative Names: CGS-21680; 3- (4- (2- ( (6-amino-9- ( (2R, 3R, 4S, 5S) -5- (ethylcarbamoyl) -3, 4-di hydroxytetra hydrofuran-2-yl) -9H-purin-2-yl) amino) ethyl) phenyl) propanoic acid). Grades: Highly Purified. CAS No. 124182-57-6. Pack Sizes: 5mg. Molecular Formula: C23H29N7O6 HCl, Molecular Weight: 536. US Biological Life Sciences. | Worldwide |
Adenosine A2A Receptor Antagonist II, SCH-58261 (2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261) Quick inquiry Where to buy Suppliers range | A highly potent and selective antagonist of adenosine A2A receptor (Ki = 600pM). Does not affect the activity of other adenosine receptors in any significant manner (Ki = 287nM; 5uM, and > 10uM for A1, A2B, and A3 receptors, respectively). Displays neuroprotective effects in cerebral ischaemia in rats, and shown to counteract Parkinsonian-like muscle rigidity in rats. CAS Number:160098-96-4. Group: Biochemicals. Grades: Highly Purified. CAS No. 160098-96-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O, Primary Target: A2A Receptor. US Biological Life Sciences. | Worldwide |
Adenosine A3 Receptor Antagonist, MRS 1523 (3-propyl-6-ethyl-5[(ethylthio)carbonyl]-2-phenyl-4-propyl-3-pyridine-carboxylate, MRS 1523, MRS-1523) Quick inquiry Where to buy Suppliers range | A pyridine derivative that acts as a highly selective antagonist of A3 receptor with excellent potency in both humans and rodents (Ki = 18.9nM for human A3R, and 113nM for rat A3R). Exhibits only a trivial antagonistic activity towards A1 and A2A receptors (Ki = 15.6uM and 2.05uM for rat A1R and A2AR, respectively). Abolishes the agonistic effects of Cl-IB-MECA on A3R-mediated proliferation of primary human coronary smooth muscle cells. Also, reported to block NECA-induced bronchoconstriction in an allergic murine model. Group: Biochemicals. Grades: Highly Purified. CAS No. 212329-37-8. Pack Sizes: 5mg. Molecular Formula: C??H??NO?S. US Biological Life Sciences. | Worldwide |
Adenosine Receptor Agonist, NECA ( (2S, 3S, 4R, 5R) -5- (6-amino-9H-purin-9-yl) -N-ethyl-3, 4-di hydroxytetra hydrofuran-2-carboxamide ) Quick inquiry Where to buy Suppliers range | A cell-permeable adenosine analog that acts a potent non-selective agonist of adenosine receptors (Ki = 14nM, 20nM, 2.4uM and 6.2nM for A1, A2A, A2B, A3, respectively). Increases intracellular cAMP production (EC50 = 3.1uM in A2B expressing CHO cells). Shown to increase glucagon release in a dose-dependent manner and inhibit insulin release at low concentrations. Although at higher concentration some insulin release is observed. Also, displays a wide range adenosine-dependent effects, such as blocking platelet aggregation and inhibiting DNA synthesis. When administered at reperfusion, it is shown reduce infarction and block the formation of the mitochondrial permeability transition pore by activating p70S6 kinase. Group: Biochemicals. Grades: Highly Purified. CAS No. 35920-39-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
Adrenergic Receptor-Targeted Compound Library Quick inquiry Where to buy Suppliers range | A unique collection of 219 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L2700. Categories: Adrenergic Receptor-Targeted Compounds Libraries. | |
AF-DX 116 (Muscarinic Receptor (mAChR) M2 Antagonist, AF-DX 116, Otenzepad, AF-DX116, AF-DX-116, AFDX116) Quick inquiry Where to buy Suppliers range | Selective presynaptic muscarinic receptor M2 antagonist with cardioselectivity. Exhibits antiarrhythmic effects in vivo, also shown to reverse the memory impairment effect of insulin in a mouse model. Group: Biochemicals. Grades: Highly Purified. CAS No. 102394-31-0. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
alpha-2-macroglobulin receptor-associated protein precursor (252-260) Quick inquiry Where to buy Suppliers range | Alpha-2-macroglobulin receptor-associated protein. Uses: Tumor Antigen Derived Peptides. CAS No. Product ID: ta-126. | |
alpha-2-macroglobulin receptor-associated protein precursor (252-260) Quick inquiry Where to buy Suppliers range | Alpha-2-macroglobulin receptor-associated protein precursor (252-260) is a peptide corresponding to residues 252-260 of alpha-2-macroglobulin receptor-associated protein precursor. Alpha-2-MRAP is a molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway. Synonyms: Alpha-2-MRAP precursor (252-260). | |
alpha,beta-methylene ATP (ab-MeATP, ab-methylene ATP, P2X Purinergic Receptor Agonist, a,b-methylene ATP, a,b-Methyleneadenosine 5?-triphosphate Lithium Salt) Quick inquiry Where to buy Suppliers range | A metabolically stable and selective P2X purinergic receptor agonist (pEC50 = 5.81) that is shown to be more potent than ATP. Elicits contractions in ileum through the release of endogenous acetylcholine, which can be blocked by tetrodotoxin (~1mM). Shown to depolarize cells of the longitudinal muscle strips (~ 200nM to 4uM) that reaches a peak within 2-3 min after application and then decays to a steady level. CAS No:104809-20-3. Group: Biochemicals. Grades: Highly Purified. CAS No. 104809-20-3. Pack Sizes: 5mg. Molecular Formula: C??H??N?O??P?; xLi+. US Biological Life Sciences. | Worldwide |
Androgen receptor antagonist 1 Quick inquiry Where to buy Suppliers range | Androgen receptor antagonist 1 is an orally available full androgen receptor antagonist (IC50 = 59 nM). It can be used in the synthesis of PROTAC AR degraders, which results in 24% and 47% AR protein degradation in LNCaP cells at 1 μM and 10 μM, respectively. Synonyms: Androgen receptor antagonist 1; 1338812-36-4; CHEMBL1916251; SCHEMBL17941138; SCHEMBL17947423; BDBM50356995; AKOS040732433; MS-27273; HY-130992; CS-0120091; N-[3-(3-chloro-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl]-1-(2-hydroxyethyl)pyrazole-4-carboxamide. Grades: 99%. CAS No. 1338812-36-4. Molecular formula: C21H25ClN4O3. Mole weight: 416.90. | |
Androgen receptor modulators 1 Quick inquiry Where to buy Suppliers range | Androgen receptor modulators 1. Group: Pheromone Ingredients. CAS No. 1114546-03-0. Molecular formula: C14H13F3N2O2. Mole weight: 298.26. | |
ATPA (2-Amino-3-(3-hydroxy-5-tert-bu-tylisoxazol-4-yl)propanoic Acid, (RS)-2-Amino-3-(3-hydroxy-5-tert-bu-tylisoxazol-4-yl)propanoic Acid, Kainate Receptor Agonist, ATPA, (R,S)-ATPA) Quick inquiry Where to buy Suppliers range | A potent agonist highly selective for GluK1-containing subtype kainate receptors (EC50 = 0.33, 0.80, and 0.38uM for GluK1, GluK1/K2, and GluK1/K5, respectively) over GluK2-containing subtypes (EC50 = 106 and ?uM for GluK2/K5 and GluK2 respectively). Weakly interacts with AMPA receptors (EC50 = 7.6, 7.9 and 22uM for GluA4, GluA3, and GluA1 respectively). Has been used in assessing the functional roles of GluK1-containing subtype kainate receptors in synaptic transmission and plasticity. Group: Biochemicals. Grades: Highly Purified. CAS No. 140158-50-5. Pack Sizes: 1mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
Bethanechol Chloride (Carbamyl-beta-methylcholine chloride, Muscarinic Acetylcholine Receptors (mAChR) Agonist, Bethanechol Chloride) Quick inquiry Where to buy Suppliers range | An agonist selective for Muscarinic Acetylcholine Receptors (mAChRs, EC50 = 7, 14.5, 35 and 32uM for M4, M3, M1 and M5 respectively) with no effect on nicotinic receptors. It is not a substrate for acetylcholinesterase therefore has longer duration of action than acetylcholine. Clinically used to treat certain bladder related conditions. Group: Biochemicals. Grades: Highly Purified. CAS No. 590-63-6. Pack Sizes: 5g. Molecular Formula: C?H??ClN?O?. US Biological Life Sciences. | Worldwide |
Bicuculline, 98+% (GABAA Receptor Antagonist, (+)-Bicuculline) Quick inquiry Where to buy Suppliers range | A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. Group: Biochemicals. Alternative Names: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; (+)-Bicuculline; d-Bicuculline; NSC 32192. Grades: Highly Purified. CAS No. 485-49-4. Pack Sizes: 100mg, 250mg. Molecular Formula: C??H??NO?, Molecular Weight: 367.35. US Biological Life Sciences. | Worldwide |
Bicuculline, 99+% (GABAA Receptor Antagonist, (+)-Bicuculline) Quick inquiry Where to buy Suppliers range | A potent allosteric antagonist of vertebrate GABAA receptors. Blocks GABAA-induced chloride currents in cultured neurons (IC50 = 740nM). Shown to increase blood pressure in spontaneously hypertensive rats and cause convulsion in experimental animals. Also, increases the amplitude of spontaneous colonic contractions. Group: Biochemicals. Alternative Names: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; (+)-Bicuculline; d-Bicuculline; NSC 32192. Grades: Highly Purified. CAS No. 485-49-4. Pack Sizes: 50mg. Molecular Formula: C??H??NO?, Molecular Weight: 367.35. US Biological Life Sciences. | Worldwide |
Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline) Quick inquiry Where to buy Suppliers range | Bicuculline (GABAA Receptor Antagonist, (+)-Bicuculline). Group: Biochemicals. Alternative Names: (6R)-6-[(5S)-5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]lisoquinolin-5-yl]furo[3,4-e]-1,3-benzodioxol-8(6H)-one; (+)-Bicuculline; d-Bicuculline; NSC 32192. Grades: Plant Grade. CAS No. 485-49-4. Pack Sizes: 20mg. Molecular Formula: C20H17NO6, Molecular Weight: 367.351999999999. US Biological Life Sciences. | Worldwide |
C3a Receptor Agonist Quick inquiry Where to buy Suppliers range | Complement 3a (C3a) Receptor Agonist is a G protein-coupled receptor protein involved in the complement system complement pathway. C3aRs are expressed on neural progenitor cells and immature neurons in adult mice. It stimulates differentiation of neural progenitor cells in vitro. Synonyms: C3A Receptor Agonist; 944997-60-8; C3a receptor agonist 1; 2-cyclohexyl-2-phenyl-N-[1-(3-pyridin-3-ylpropanoyl)piperidin-4-yl]acetamide; CHEMBL390036; CHEMBL535625; 2-cyclohexyl-2-phenyl-N-(1-(3-(pyridin-3-yl)propanoyl)piperidin-4-yl)acetamide; 2-Cyclohexyl-2-phenyl-N-{1-[3-(pyridin-3-yl)propanoyl]piperidin-4-yl}acetamide; Complement 3a Receptor Agonist; SCHEMBL14335900; GTPL11252; DTXSID90659061; BDBM50423085; AKOS028114559; compound 7 [PMID: 17459702]; MS-27755; HY-128132; CS-0095343; C3A Receptor Agonist, >=98% (HPLC), solid; F87576. Grades: ≥98%. CAS No. 944997-60-8. Molecular formula: C27H35N3O2. Mole weight: 433.6. | |
Calcium-Sensing Receptor Antagonists I Quick inquiry Where to buy Suppliers range | Calcium-Sensing Receptor Antagonists I is an antagonist of calcium-sensing parathyroid hormone receptors. Synonyms: 2(1H)-Quinazolinone, 1-(1-methylethyl)-4-[4-(1-methylethyl)phenyl]-6-(2-propyn-1-yloxy)-. Grades: >98%. CAS No. 478963-79-0. Molecular formula: C23H24N2O2. Mole weight: 360.45. | |
CGP 35348 (GABAB Receptor Antagonist, CGP 35348, CGP35348, CGP-35348) Quick inquiry Where to buy Suppliers range | A selective antagonist of post-synaptic GABAB receptors (IC50 = 34uM) that can permeate the blood brain barrier. Exhibits about 10-fold lower affinity for pre-synaptic receptors. Blocks K+-evoked glycine exocytosis in mouse spinal cord and hippocampal nerve endings. Shown to antagonize the potentiating effect of L-baclofen on noradrenaline-induced stimulation of adenylate cyclase in rat cortex slices. Group: Biochemicals. Grades: Highly Purified. CAS No. 123690-79-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CGP 7930 (GABA B Receptor Antagonist, CGP7930, CGP 7930, CGP-7930) Quick inquiry Where to buy Suppliers range | A blood brain barrier permeable, positive allosteric modulator of the metabotropic GABAB receptor. Shown to modulate GABAB receptor in the high affinity state and thereby increases agonist affinity for the receptor. Also enhances agonist potency and efficacy even on recombinant GABAB receptors. Exhibits anxiolytic effects in rodents. Group: Biochemicals. Grades: Highly Purified. CAS No. 57717-80-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
CTAP (Mu Opioid Receptor Antagonist, CTAP) Quick inquiry Where to buy Suppliers range | A highly potent octapeptide that acts as a selective and brain penetrating bioavailable u opioid receptor antagonist (IC50 = 3.5nM). Used in studies of reward systems and additions. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-32-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
CTOP (Mu Opioid Receptor Antagonist, CTOP) Quick inquiry Where to buy Suppliers range | A potent antagonist highly selective for Mu opioid receptor (Ki = 0.96nM for u receptor and > 10,000nM for delta receptors). Often used for studying the functional roles of Mu opioid receptors in both central and peripheral nervous systems. Group: Biochemicals. Grades: Highly Purified. CAS No. 103429-31-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
Dopamine Receptor D2 Control Peptide (DRD2) Quick inquiry Where to buy Suppliers range | Dopamine Receptor D2 Control Peptide (DRD2). Group: Molecular Biology. Grades: Purified. Pack Sizes: 150nmole. US Biological Life Sciences. | Worldwide |