Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. Group: Biochemicals. Alternative Names: 4- [4- [ [ [ [4-Chloro-3- (trifluoromethyl) phenyl] amino] carbonyl] amino] -3-fluorophenoxy] -N-methyl-2-pyridinecarboxamide; 4-[4-[N- (4-Chloro-3-trifluoromethylphenyl) ureido]-3-fluorophenoxy]pyridine-2-carboxylic Acid Methylamide; BAY 73-4506; Fluoro-Sorafenib; Stivarga. Grades: Highly Purified. CAS No. 755037-03-7. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C??H??ClF?N?O?, Molecular Weight: 482.82. US Biological Life Sciences.
Worldwide
Regorafenib
Regorafenib (BAY 73-4506) is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 , respectively. Regorafenib shows very robust antitumor and antiangiogenic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 73-4506. CAS No. 755037-03-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10331.
Regorafenib EP Impurity A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 757251-39-1. Molecular Formula: C13H12FN3O2. Mole Weight: 261.26. Catalog: APB757251391.
Regorafenib EP Impurity B
Regorafenib EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2141961-84-2. Molecular Formula: C15H14FN3O3. Mole Weight: 303.29. Catalog: APB2141961842.
Regorafenib EP Impurity D
An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4,4'-(((carbonylbis(azanediyl))bis(3-fluoro-4,1-phenylene))bis(oxy))bis(N-methylpicolinamide). CAS No. 2438857-80-6. Molecular formula: C27H22F2N6O5. Mole weight: 548.50.
Regorafenib EP Impurity D
Regorafenib EP Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2438857-80-6. Molecular Formula: C27H22F2N6O5. Mole Weight: 548.51. Catalog: APB2438857806.
Regorafenib Hydrochloride
Regorafenib Hydrochloride (BAY 73-4506 hydrochloride) is a multi-target inhibitor for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 with IC 50 s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 73-4506 hydrochloride. CAS No. 835621-07-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13308.
Regorafenib Hydrochloride
Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1. Synonyms: BAY73-4506 hydrochloride. Grades: >98%. CAS No. 835621-07-3. Molecular formula: C21H16Cl2F4N4O3. Mole weight: 519.28.
Regorafenib Impurity 1
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C25H19F2N5O4. Mole weight: 491.46.
Regorafenib Impurity 10
Regorafenib Impurity 10. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2098799-12-1. Molecular Formula: C19H17FN4O3. Mole Weight: 368.37. Catalog: APB2098799121.
Regorafenib Impurity 13
Regorafenib Impurity 13. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2909-32-2. Molecular Formula: C14H14N2O. Mole Weight: 226.28. Catalog: APB2909322.
Regorafenib Impurity 14
Regorafenib Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 835621-12-0. Molecular Formula: C20H13ClF4N4O4. Mole Weight: 484.79. Catalog: APB835621120.
Regorafenib Impurity 15
Regorafenib Impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1343498-72-5. Molecular Formula: C20H13ClF4N4O3. Mole Weight: 468.79. Catalog: APB1343498725.
Regorafenib Impurity 16
Regorafenib Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1343498-71-4. Molecular Formula: C21H15ClF4N4O4. Mole Weight: 498.82. Catalog: APB1343498714.
Regorafenib Impurity 17
Regorafenib Impurity 17. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2545933-24-0. Molecular Formula: C25H22FN5O4. Mole Weight: 475.48. Catalog: APB2545933240.
Regorafenib Impurity 18 (Sorafenib Impurity 8)
Regorafenib Impurity 18 (Sorafenib Impurity 8). Uses: For analytical and research use. Group: Impurity standards. CAS No. 1379324-09-0. Molecular Formula: C7H6Cl2N2O. Mole Weight: 205.04. Catalog: APB1379324090.
Regorafenib Impurity 2
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C21H16F4N4O3. Mole weight: 448.38.
Regorafenib Impurity 20
Regorafenib Impurity 20. Uses: For analytical and research use. Group: Impurity standards. CAS No. 370-50-3. Molecular Formula: C15H8Cl2F6N2O. Mole Weight: 417.13. Catalog: APB370503.
Regorafenib Impurity 21
Regorafenib Impurity 21. Uses: For analytical and research use. Group: Impurity standards. CAS No. 9448-54-5. Molecular Formula: C9H7ClF3NO2. Mole Weight: 253.61. Catalog: APB9448545.
Regorafenib Impurity 27
Regorafenib Impurity 27. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1333390-56-9. Molecular Formula: C14H9ClF4N2O2. Mole Weight: 348.68. Catalog: APB1333390569.
Regorafenib Impurity 29
Regorafenib Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 352277-93-1. Molecular Formula: C12H13ClF3NO2. Mole Weight: 295.69. Catalog: APB352277931.
Regorafenib Impurity 3
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C21H15ClF4N4O3. Mole weight: 482.83.
Regorafenib Impurity 4
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C20H18FN5O3. Mole weight: 395.4.
Regorafenib Impurity 5
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C27H22F2N6O5. Mole weight: 548.51.
Regorafenib Impurity 50
Regorafenib Impurity 50. Uses: For analytical and research use. Group: Impurity standards. CAS No. 6636-55-1. Molecular Formula: C7H6ClNO2. Mole Weight: 171.58. Catalog: APB6636551.
Regorafenib Impurity 51
Regorafenib Impurity 51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 98273-19-9. Molecular Formula: C7H5Cl2NO2. Mole Weight: 206.02. Catalog: APB98273199.
Regorafenib Impurity 58
Regorafenib Impurity 58. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2126178-55-8. Molecular Formula: C2013CH12D3ClF4N4O3. Mole Weight: 486.83. Catalog: APB2126178558.
Regorafenib Impurity 6
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Impurity 6; Regorafenib metabolite M6; 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinic acid; ZU2HG2Y956; UNII-ZU2HG2Y956; 2-Pyridinecarboxylic acid, 4- (4- ( ( ( (4-chloro-3- (trifluoromethyl) phenyl) amino) carbonyl) amino) -3-fluorophenoxy) -; 4- (4- ( (4-Chloro-3- (trifluoromethyl) phenyl) carbamoylamino) -3-fluoro-phenoxy) pyridine-2-carboxylic acid; 4-[4-[[4-chloro-3- (trifluoromethyl) phenyl]carbamoylamino]-3-fluorophenoxy]pyridine-2-carboxylic acid; SCHEMBL4609009; 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy) picolinic acid. Grades: > 95%. CAS No. 1187945-05-6. Molecular formula: C20H12ClF4N3O4. Mole weight: 469.78.
Regorafenib Impurity 60
Regorafenib Impurity 60. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2232228-54-3. Molecular Formula: C27H23ClF4N4O9. Mole Weight: 658.94. Catalog: APB2232228543.
Regorafenib Impurity 62
Regorafenib Impurity 62. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1855006-12-0. Molecular Formula: C20H18FN5O3. Mole Weight: 395.39. Catalog: APB1855006120.
Regorafenib Impurity 63
Regorafenib Impurity 63. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2098799-13-2. Molecular Formula: C35H23Cl2F7N6O5. Mole Weight: 811.49. Catalog: APB2098799132.
Regorafenib Impurity 67
Regorafenib Impurity 67. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1446410-29-2. Molecular Formula: C8H10ClN3O. Mole Weight: 199.64. Catalog: APB1446410292.
Regorafenib Impurity 7
An impurity of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C36H24Cl2F7N5O5. Mole weight: 810.52.
Regorafenib Impurity 7
Regorafenib Impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 835621-11-9. Molecular Formula: C21H15ClF4N4O4. Mole Weight: 498.82. Catalog: APB835621119.
Regorafenib Impurity 74
Regorafenib Impurity 74. Uses: For analytical and research use. Group: Impurity standards. CAS No. 50528-86-4. Molecular Formula: C8H3ClF3NO. Mole Weight: 221.56. Catalog: APB50528864.
Regorafenib Impurity 9
Regorafenib Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2188236-16-8. Molecular Formula: C21H16F4N4O3. Mole Weight: 448.38. Catalog: APB2188236168.
Regorafenib monohydrate
Regorafenib (BAY 73-4506) monohydrate is an orally active and potent multi-targeted receptor tyrosine kinase inhibitor, with IC 50 values of 13/4.2/46, 22, 7, 1.5 and 2.5 nM for VEGFR1/2/3 , PDGFRβ , Kit , RET and Raf-1 , respectively. Regorafenib monohydrate shows very robust antitumor and antiangiogenic activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 73-4506 monohydrate. CAS No. 1019206-88-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10331A.
Regorafenib monohydrate
Regorafenib monohydrate is a multitargetedinhibitor of tyrosine kinase with IC50 values of 13nM, 4.2nM, 46nM, 2.5nM, 28nM, 19nM, 202nM, 22nM, 7nM, 1.5nM and 311nM, respectively for VEGFR-1, mVEGFR-2, mVEGFR-3, Raf-1, BRAF WT, BRAFV600E, FGFR-1, PDGFR-β, c-KIT, RET and TIE2. Synonyms: BAY 73-4506. Grades: >98%. CAS No. 1019206-88-2. Molecular formula: C21H17ClF4N4O4. Mole weight: 500.83.
Regorafenib monohydrate impurity B [EP]
An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Impurity 02; 4-(4-acetamido-3-fluorophenoxy)-N-methylpicolinamide. CAS No. 2141961-84-2. Molecular formula: C15H14FN3O3. Mole weight: 303.29.
Regorafenib monohydrate impurity C [EP]
An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpyridine-2-carboxamide; 4-(3-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide. CAS No. 1855006-12-0. Molecular formula: C20H18FN5O3. Mole weight: 395.39.
Regorafenib N-β-D-Glucuronide Methyl Ester
Regorafenib N-β-D-Glucuronide Methyl Ester, an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, is a derivative of Regorafenib. It is a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. as well as useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2S,3S,4S,5R,6R)-Methyl 6-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate. Molecular formula: C28H25ClF4N4O9. Mole weight: 672.97.
Regorafenib N-β-D-Glucuronide (Pyridine)-N-oxide
A derivative of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C27H23ClF4N4O10. Mole weight: 647.95.
Regorafenib N-β-D-Glucuronide Sodium Salt
A derivative of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: (2S,3S,4S,5R,6R)-6-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic Acid Sodium Salt. Grades: > 95%. Molecular formula: C27H22ClF4N4NaO9. Mole weight: 680.92.
A metabolite of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-2-pyridinecarboxamide 1-Oxide. Grades: > 95%. CAS No. 835621-11-9. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82.
Hydroxyregorafenib
A derivative of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Grades: > 95%. Molecular formula: C21H15ClF4N4O4. Mole weight: 498.82.
N-Desmethyl Regorafenib
N-Desmethyl Regorafenib is a metabolite of Regorafenib. Regorafenib is useful for the treatment of inflammation and as an anti-proliferative agent. Uses: A metabolite of regorafenib. Synonyms: BAY-751098; BAY 751098; BAY751098; Regorafenib metabolite M4;UNII-58I22S7HYD;4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)picolinamide. Grades: 98%. CAS No. 1343498-72-5. Molecular formula: C20H13ClF4N4O3. Mole weight: 468.79.
N-Desmethyl Regorafenib N-Oxide (M5 Metabolite)
A metabolite of Regorafenib.Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: 4-[4-[[[[4-Chloro-3- (trifluoromethyl) phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-2-pyridinecarboxamide 1-Oxide. Grades: > 95%. CAS No. 835621-12-0. Molecular formula: C20H13ClF4N4O4. Mole weight: 484.79.
Sorafenib Impurity 5 (Regorafenib Impurity 5)
Sorafenib Impurity 5 (Regorafenib Impurity 5). Uses: For analytical and research use. Group: Impurity standards. CAS No. 320-51-4. Molecular Formula: C7H5ClF3N. Mole Weight: 195.57. Catalog: APB320514.
An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Urea Impurity; Urea, N-[4-chloro-3-(trifluoromethyl)phenyl]-N'-(2-fluoro-4-hydroxyphenyl)-. CAS No. 1333390-56-9. Molecular formula: C14H9ClF4N2O2. Mole weight: 348.68.
5-Amino-2-chlorobenzotrifluoride N-Chloroacetyl N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, which is a derivative of Regorafenib and a compound that inhibits PDGFR tyrosine kinase with IC50 = 83 nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2R, 3R, 4S, 5S, 6S)-2- ( (4-Chloro-3- (trifluoromethyl)phenyl) (chlorocarbonyl)amino)-6- (methoxycarbonyl)tetrahydro-2H-pyran-3, 4, 5-triyl Triacetate. Molecular formula: C21H20Cl2F3NO10. Mole weight: 574.29.
5-Amino-2-chlorobenzotrifluoride N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt, which is a derivative of Regorafenib and a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent. Synonyms: (2R,3R,4S,5S,6S)-2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate. Molecular formula: C20H21ClF3NO9. Mole weight: 511.83.
An impurity of Regorafenib. Regorafenib is a multi-kinase inhibitor which targets angiogenic, stromal and oncogenic receptor tyrosine kinase. It shows anti-angiogenic activity due to its dual targeted VEGFR2-TIE2 tyrosine kinase inhibition. Synonyms: Regorafenib Impurity 06. CAS No. 2514957-39-0. Molecular formula: C16H16FN3O4. Mole weight: 333.31.
Would you like to list your products on USA Chemical Suppliers?
Our database is helping our users find suppliers everyday.