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| Product | Description | |
|---|---|---|
| Remdesivir | Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC 50 s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-5734. CAS No. 1809249-37-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-104077. |  |
| Remdesivir | Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC50s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro. Uses: Designed for use in research and industrial production. Additional or Alternative Names: GS-5734; 2-Ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate. Product Category: Inhibitors. Appearance: White solid. CAS No. 1809249-37-3. Molecular formula: C27H35N6O8P. Mole weight: 602.58. Purity: 0.98. IUPACName: 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate. Canonical SMILES: CCC(CC)COC(=O)[C@H](C)N[P@](=O)(OC[C@@H]1[C@H]([C@H]([C@](O1)(C#N)C2=CC=C3N2N=CN=C3N)O)O)OC4=CC=CC=C4. Product ID: ACM1809249373. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Remdesivir | Remdesivir Inhibitor. Uses: Scientific use. Product Category: T7766. CAS No. 1809249-37-3. |  |
| Remdesivir p-NitroPhenoxy L-Alanine Impurity | Remdesivir p-NitroPhenoxy L-Alanine Impurity. Synonyms: (S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate; (2S)-2-ethylbutyl 2-(((4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate. CAS No. 1354823-36-1. Molecular formula: C21H27N2O7P. Mole weight: 450.4. |  |
| Remdesivir (Standard) | Remdesivir (Standard) is the analytical standard of Remdesivir. This product is intended for research and analytical applications. Remdesivir (GS-5734), a nucleoside analogue with effective antiviral activity, has EC 50 s of 3.3 μM, 4.7 μM, 32 μM, 3.7 μM and 9.2 μM for SARS-CoV-2 and its variants alpha, beta, gamma and delta, respectively. Remdesivir is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1809249-37-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104077R. | |
| 4-amino-7-iodopyrrolo(2,1-f)(1,2,4)triazine | 4-amino-7-iodopyrrolo(2,1-f)(1,2,4)triazine (CAS# 1770840-43-1 ) is a useful research chemical. Synonyms: Remdesivir-004; 7-Iodopyrrolo[2,?1-f]?[1,?2,?4]?triazin-4-amine; Pyrrolo[2,1-f][1,2,4]triazin-4-amine, 7-iodo-; Remdesivir Related Compound 2. CAS No. 1770840-43-1. Molecular formula: C6H5IN4. Mole weight: 260.04. | |
| Anti-COVID-19 Compound Library | A unique collection of 1160 compounds with confirmed anti-SARS-CoV-2 activity or potential activity and part of them are broad-spectrum antiviral agents?- Compounds contain Remdesivir, Lopinavir/Ritonavir, Chloroquine diphosphate (combination use with Remdesivir), Polydatin (bind with Mpro), etc. ?- Detailed compound information with structure, target, and biological activity description?- NMR and HPLC/LCMS validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1710. Categories: Anti-COVID-19 Compounds Libraries. | |
| Anti-virus agent 1 | Anti-virus agent 1 (compound 4i), a phosphoramidate proagent of GS-5734 (HY-104077; Remdesivir), has potent antiviral activity. Anti-virus agent 1 is used for the research of coronavirus and Ebola virus (EBOV) [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Remdesivir isopropyl ester analog. CAS No. 1911578-83-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131233. | |
| GS-441524 | GS-441524 is an analog nucleotide inhibitor against feline infectious peritonitis virus (FIPV). EC50 is 0.78?uM. GS-441524 is also a metabolite and intermediate of Remdesivir. Synonyms: 2-C-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-2,5-anhydro-D-altrononitrile; Remdesivir metabolite GS-441524; GS 441524; GS441524; (2R,3R,4S,5R)-2-(4-Aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile. Grade: 97%. CAS No. 1191237-69-0. Molecular formula: C12H13N5O4. Mole weight: 291.26. | |
| GS-441524 | GS-441524, predominant metabolite of Remdesivir and superior to Remdesivir against Covid-19 , shows comparable efficacy in cell-based models of primary human lung and cat cells infected with coronavirus. GS-441524 could strongly inhibits feline infectious peritonitis virus (FIPV), with an EC 50 of 0.78 μM [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1191237-69-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-103586. | |
| GS-443902 | GS-443902 is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. Uses: Antiviral agents. Synonyms: GS-441524 triphosphate; Remdesivir metabolite; RDV-TP. Grade: 99.87%. CAS No. 1355149-45-9. Molecular formula: C12H16N5O13P3. Mole weight: 531.20. | |
| GS-443902 trisodium | GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 ?M, 5 ?M for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734)[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium. CAS No. 1355050-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126303C. | |
| GS-443902 trisodium | GS-443902 trisodium is a potent inhibitor of viral RNA-dependent RNA-polymerases (RdRp), with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. Synonyms: GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium. Grade: 99%. CAS No. 1355050-21-3. Molecular formula: C12H12N5Na4O13P3. Mole weight: 619.13. | |
| GS-621763 | GS-621763 is an orally bioavailable prodrug of GS-441524. The nucleoside metabolite of remdesivir, GS-441524 displays potent anti-SARS-CoV-2 efficacy, and is being evaluated in clinical as an oral antiviral therapeutic for COVID-19. Synonyms: GS-441524 prodrug. Grade: 98%. CAS No. 2647442-13-3. Molecular formula: C24H31N5O7. Mole weight: 501.53. | |
| (S)-2-Ethylbutyl 2-Aminopropanoate Hydrochloride | An intermediate of Remdesivir, a broad-spectrum antiviral medication against several RNA viruses. Synonyms: L-Alanine 2-ethylbutyl ester hydrochloride; 2-ethylbutyl (2S)-2-aminopropanoate; hydrochloride. CAS No. 946511-97-3. Molecular formula: C9H20ClNO2. Mole weight: 209.71. | |
| Simeprevir | Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a K i of 0.36 nM. Simeprevir inhibits HCV replication with an EC 50 of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (M pro ) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses [1] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TMC435; TMC435350. CAS No. 923604-59-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10241. | |
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