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Resiquimod is an imidazoquinolinamine and TLR7 agonist with antitumor and antiviral activity. Uses: Resiquimod may be used in immunological and cancer-related cell signaling studies. Synonyms: R-848; R 848; R848; S 28463; S-28463; S28463; 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-α,α-dimethyl-; 4-Amino-2-(ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline; Resimiquimod. Grades: ≥95%. CAS No. 144875-48-9. Molecular formula: C17H22N4O2. Mole weight: 314.38.
Resiquimod
Resiquimod is a Toll-like receptor 7 and 8 (TLR7/TLR8) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-α. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RESIQUIMOD;1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-C]quinolin-1-yl]-2-methylpropan-2-ol;Chebi:36706;4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol;4-Amino-2-(ethoxymethyl)-alpha;alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol;resquimod;R848,Resiquimod. Product Category: Inhibitors. CAS No. 144875-48-9. Molecular formula: C17H22N4O2. Mole weight: 314.387. Purity: 0.9996. Density: 1.28. Product ID: ACM144875489. Alfa Chemistry ISO 9001:2015 Certified.
Resiquimod
Resiquimod is a Toll-like receptor 7 and 8 ( TLR7/TLR8 ) agonist that induces the upregulation of cytokines such as TNF-α, IL-6 and IFN-&alpha. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R848; S28463. CAS No. 144875-48-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-13740.
Resiquimod (R-848, S 28463)
Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus. Group: Biochemicals. Alternative Names: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; 4-Amino-2- (ethoxymethyl) -1- (2-hydroxyisobutyl) imidazo[4, 5-c]quinoline; 4-Amino-2-ethoxymethyl-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; R 848; Resiquimod; S 28463. Grades: Highly Purified. CAS No. 144875-48-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N?O?, Molecular Weight: 314.4. US Biological Life Sciences.
1-[(3-Amino-4-quinolinyl)amino]-2-methyl-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 129655-59-0. Pack Sizes: 100mg, 250mg. Molecular Formula: C13H17N3O, Molecular Weight: 231.29. US Biological Life Sciences.
2-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5 is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg, 10mg. Molecular Formula: C17H16D5N3O2, Molecular Weight: 304.399999999999. US Biological Life Sciences.
2-Methyl-1-[(3-nitro-4-quinolinyl)amino]-2-propanol is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist. Group: Biochemicals. Grades: Highly Purified. CAS No. 129655-57-8. Pack Sizes: 250mg, 500mg. Molecular Formula: C13H15N3O3, Molecular Weight: 261.279999999999. US Biological Life Sciences.
Worldwide
Gardiquimod TFA
Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. The core structure is 1H-imidazo[4,5-c]quinoline, as found in related drugs such as imiquimod and resiquimod. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Gardiquimod TFA salt; Gardiquimod. Product Category: Others. Appearance: Solid powder. CAS No. 1159840-61-5. Molecular formula: C19H24F3N5O3. Mole weight: 427.43. Purity: >98%. IUPACName: 1-(4-amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol 2,2,2-trifluoroacetate. Canonical SMILES: CC(O)(C)CN1C(CNCC)=NC2=C1C3=CC=CC=C3N=C2N.O=C(O)C(F)(F)F. Product ID: ACM1159840615. Alfa Chemistry ISO 9001:2015 Certified. Categories: Gardiquimod trifluoroacetate.
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