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Reticulol An isocoumarin metabolite produced by selected species of streptomyces. It is a potent inhibitor of cyclic nucleotide phosphodiesterase. It also causes dose-dependent inhibition of lung metastasis in the B16F10 melanoma model. Synonyms: 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin; 6,8-Dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one; K 251-1; NSC 294978. Grades: >95% by HPLC. CAS No. 26246-41-3. Molecular formula: C11H10O5. Mole weight: 222.19. BOC Sciences 5
Reticulol Antibiotic. Cyclic adenosine 3',5'-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor. Antitumor compound. Group: Biochemicals. Alternative Names: 6,8-Dihydroxy-7-methoxy-3-methyl-1H-2-benzopyran-1-one; 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin; K 251-1; NSC 294978; Reticulol; 6,8-Dihydroxy-7-methoxy-3-methyl-isocoumarin. Grades: Highly Purified. CAS No. 26246-41-3. Pack Sizes: 250ug, 1mg. Molecular Formula: C??H??O?. US Biological Life Sciences. USBiological 4
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Reticulol (6,8-Dihydroxy-7-methoxy-3-methylisocoumarin) Reticulol is an isocoumarin metabolite produced by selected species of Streptomyces. Reticulol was first described as a potent inhibitor of cyclic nucleotide phosphodiesterase but more recent research has demonstrated a topoisomerase I inactivation mechanism. Reticulol has also been demonstrated to cause a dose dependent inhibition of lung metastasis in the B16F10 melanoma model. Group: Biochemicals. Alternative Names: 6,8-Dihydroxy-7-methoxy-3-methylisocoumarin. Grades: Highly Purified. CAS No. 26246-41-3. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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