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25g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C8H12N4O5. CAS No. 36791-04-5. Prepack ID 18793733-25g. Molecular Weight 244.2. See USA prepack pricing.
Ribavirin
Ribavirin (ICN-1229) is an antiviral agent against a broad spectrum of viruses including HCV , HIVl , and RSV. Ribavirin also has anti- orthopoxvirus and anti-variola activities. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ribasphere. CAS No. 36791-04-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0434.
Ribavirin
Ribavirin is a guanosine (ribonucleic) analog used to stop viral RNA synthesis and viral mRNA capping, thus, it is a nucleoside inhibitor. Synonyms: 1-b-D-ribafuranosyl-1H-1,2,4-triazole-3-carboxamide; MegaRibavirin; NSC 163039; Ravanex; Rebetol; Ribamide; Ribamidil; Ribasphere; Ribavarin; Tribavirin; Vilona; Viramid; Virazole; Virizadole; 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide. Grades: ≥95%. CAS No. 36791-04-5. Molecular formula: C8H12N4O5. Mole weight: 244.20.
Ribavirin
Ribavirin is a nucleoside analog that inhibits the replication of both DNA and RNA viruses, including influenza type A and type B. Ribavirin, as ribavirin 5-phosphate, affects virus-infected cells primarily by inhibiting the enzyme inosine 5-monophosphate (IMP) dehydrogenase. It potently suppresses eIF4E-mediated oncogenic transformation of murine cells in vitro, of tumor growth of a mouse model of eIF4E-dependent human squamous cell carcinoma in vivo, and of colony formation of eIF4E-dependent acute myelogenous leukemia cells derived from human patients. Group: Biochemicals. Alternative Names: 1-ß-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide, ICN-1229, Rebetol, Viramid, Virazid, Virazole. Grades: Highly Purified. CAS No. 36791-04-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C8H12N4O5, Molecular Weight: 244.2. US Biological Life Sciences.
Labeled Rivavirin, which is used as an antiviral agent. Group: Biochemicals. Alternative Names: 1-ß-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide-13C5. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Ribavirin 2,3,5-Tri-O-acetyl
As a purine nucleoside analog, protected Ribavirin inhibits inosine monophosphate dehydrogenase. It could be used as an antiviral agent. This compound is suitable for pyruvate dehydrogenase (PDH) related research. Synonyms: 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1,2,4-triazole-3-carboxamide; Tri-O-acetylribavirin; 1-(2,3,5-Tri-O-acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide. CAS No. 40372-03-0. Molecular formula: C14H18N4O8. Mole weight: 370.31.
Ribavirin 5'-diphosphate lithium salt
Ribavirin 5'-diphosphate lithium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 63142-70-1. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C8H12N4O11P2Li2. US Biological Life Sciences.
Worldwide
Ribavirin 5'-Diphosphate Lithium Salt
A derivative of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Grades: > 95%. CAS No. 63142-70-1. Molecular formula: C8H12N4O11P2.2 Li. Mole weight: 416.03.
Ribavirin 5'-monophosphate diammonium salt
Ribavirin 5'-monophosphate diammonium salt is a pivotal biomedical compound, exhibiting profound applications in studying viral infections, including hepatitis C and respiratory syncytial virus (RSV). Its antiviral mechanism impairs viral RNA replication and dissemination. By assuming a salt configuration, Ribavirin 5'-monophosphate ameliorates its stability and solubility. Synonyms: Virazole 5'-monophosphate. Molecular formula: C8H19N6O8P. Mole weight: 358.25.
Ribavirin 5-Monophosphate, Dilithium Salt
A metabolite of Ribavirin. Used as an antiviral agent. Group: Biochemicals. Alternative Names: 1-(5-O-Phosphono- β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide Dilithium Salt. Grades: Highly Purified. CAS No. 66983-94-6. Pack Sizes: 5mg. Molecular Formula: C?H??Li?N?O?P, Molecular Weight: 336.05. US Biological Life Sciences.
Worldwide
Ribavirin 5'-monophosphate lithium salt
Ribavirin 5'-monophosphate is a metabolite of ribavirin, displaying broad-spectrum antiviral activity. It inhibits viral DNA and RNA replication in vitro via suppression of inosine monophosphate dehydrogenase (IMPDH), resulting in inhibition of guanosine triphosphate synthesis. Synonyms: Dilithium [5-(3-carbamoyl-1,2,4-triazol-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate. Grades: ≥95%. CAS No. 66983-94-6. Molecular formula: C8H11N4O8P·2Li. Mole weight: 336.1.
Ribavirin 5'-monophosphate sodium salt
Ribavirin 5'-monophosphate sodium salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 40925-28-8. Pack Sizes: 2mg. Molecular Formula: C8H13N4O8P·xNa. US Biological Life Sciences.
Worldwide
Ribavirin 5'-triphosphate
A derivative of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Grades: > 95%. CAS No. 63142-71-. Molecular formula: C8H14N4O14P3. Mole weight: 484.14.
Ribavirin 5'-triphosphate sodium salt
Ribavirin 5'-triphosphate sodium salt juxtaposes as a formidable compound used in studying relentless chronic hepatitis C virus infection. Its exceptional prowess resides in its robust hindrance of viral RNA synthesis, thus forestalling the perils of replication. Synonyms: 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate; 1-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-b-D-ribofuranosyl]-1H-1, 2, 4-triazole-3-carboxamide trisodium; Virazole 5'-triphosphate trisodium. Grades: ≥ 95%. Molecular formula: C8H15N4O14P3·xNa. Mole weight: 484.14 (free acid).
Ribavirin 5'-triphosphate tetrasodium salt
Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA. Uses: Antiviral agents. Synonyms: 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate; 1-[5-O-[Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-b-D-ribofuranosyl]-1H-1, 2, 4-triazole-3-carboxamide tetrasodium; Hydroxy[[hydroxy (phosphonooxy) phosphinyl]oxy]phosphinyl]-b-D-ribofuranosyl]-1H-1, 2, 4-triazole-3-carboxamide tetrasodium. Grades: ≥ 95% (HPLC). CAS No. 63142-71-2. Molecular formula: C8H15N4O14P3·Na4. Mole weight: 576.10.
Ribavirin 5'-triphosphate triethylammonium salt
Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA. Synonyms: 1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide-5'-triphosphate. Grades: ≥ 95% (HPLC). Molecular formula: C8H14N4O14P3·3C6H16N. Mole weight: 789.73.
Ribavirin Impurity A
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: Ribavirin carboxylic acid; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxylic Acid; USP Ribavirin Impurity A; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxylic acid. Grades: ≥95%. CAS No. 39925-19-4. Molecular formula: C8H11N3O6. Mole weight: 245.19.
Ribavirin Impurity B
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: 1-α-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; Ribavirin Impurity B; α-Ribavirin. Grades: > 95%. CAS No. 57198-02-4. Molecular formula: C8H12N4O5. Mole weight: 244.21.
Ribavirin Impurity D
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: USP Ribavirin Related Compound D: 1H-1,2,4-Triazole-3-carboxamide; s-Triazole-3-carboxamide; 1,2,4-Triazole-3-carboxamide; NSC 80860; Ribavirin EP Impurity D;N-Des-1-β-D-ribofuranosyl Ribavirin. Grades: > 95%. CAS No. 3641-8-5. Molecular formula: C3H4N4O. Mole weight: 112.09.
Ribavirin Impurity E
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: 1-(5-O-benzoyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide; Ribavirin Impurity E;5'-O-Benzoyl Ribavirin. Grades: > 95%. CAS No. 58151-90-9. Molecular formula: C15H16N4O6. Mole weight: 348.32.
Ribavirin Impurity F
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: 5'-O-Acetyl Ribavirin; 1-(5-O-Acetyl-β-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide; Ribavirin Impurity F. Grades: > 95%. CAS No. 58151-87-4. Molecular formula: C10H14N4O6. Mole weight: 286.25.
Ribavirin Impurity G
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: 1-β-D-Ribofuranosyl-1H-1,2,4-triazole-5-carboxamide; Ribavirin Impurity G; Iso Ribavirin (Ribavirin Impurity G). Grades: > 95%. CAS No. 39030-43-8. Molecular formula: C8H12N4O5. Mole weight: 244.21.
Ribavirin Monophosphate
Ribavirin-5'-monophosphate is a potent competitive inhibitor of inosine 5'-phosphate dehydrogenase. In addition, Ribavirin 5'-monophosphate inhibits viral DNA and RNA replication in vitro via the strong competitive inhibition of inosine monophosphate dehydrogenase (IMPDH) (Ki= 270 nM). Uses: Antiviral agents. Synonyms: Sodium salt. Grades: ≥ 95 % by HPLC. CAS No. 40925-28-8. Molecular formula: C8H13N4O8P (free acid). Mole weight: 324.18 (free acid).
Ribavirin-(ribofuranosyl-13C5)
?98 atom % 13C, ?95% (CP). Group: Fluorescence/luminescence spectroscopy.
Protected Ribavirin impurity B. Uses: Protected ribavirin impurity b. Synonyms: 1-(2',3'-Isopropylidene-α-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide. CAS No. 69313-80-0. Molecular formula: C11H16N4O5. Mole weight: 285.27.
2,3-Isopropylidene ribavirin
2,3-Isopropylidene ribavirin, an exceedingly potent antiviral agent, serves as a crucial therapeutic solution for the management of hepatitis C virus (HCV) infection. With its robust inhibitory prowess exhibited against HCV RNA-dependent RNA polymerase, it remarkably curtails viral replication. Synonyms: 1-[2,3-O-(1-Methylethylidene)-b-D-ribofuranosyl]-1H-1,2,4-triazole-3-carboxamide. CAS No. 52663-90-8. Molecular formula: C11H16N4O5. Mole weight: 284.27.
a-Ribavirin (impurity B)
a-Ribavirin (impurity B). Group: Biochemicals. Grades: Highly Purified. CAS No. 57198-02-4. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C8H12N4O5. US Biological Life Sciences.
Worldwide
Taribavirin
Taribavirin is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin, is a ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 119567-79-2. Molecular formula: C8H13N5O4. Mole weight: 243.2217. Canonical SMILES: N=C(C1=NN([C@H]2[C@@H]([C@@H]([C@@H](CO)O2)O)O)C=N1)N. Product ID: ACM119567792. Alfa Chemistry ISO 9001:2015 Certified.
Taribavirin hydrochloride
Taribavirin hydrochloride is an orally active inosine monophosphate dehydrogenase inhibitor, has activity against a wide range of viruses, especially the hepatitis C virus and influenza virus. Taribavirin hydrochloride is a Ribavirin proagent, is designed to concentrate within the liver to target HCV-infected hepatocytes while minimizing distribution within red blood cells (RBCs) and the development of hemolytic anemia [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 40372-00-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10545A.
An impurity of Ribavirin. Ribavirin is an anti-viral medication used to treat RSV infection, hepatitis C, and viral hemorrhagic fever. Synonyms: 1H-1,2,4-Triazole-3-carboxylic acid; s-Triazole-3-carboxylic acid; 4H-1,2,4-Triazole-3-carboxylic acid; NSC 165527; NSC 202574; Ribavirin EP Impurity C; Ribavirin Impurity C. Grades: ≥95%. CAS No. 4928-87-4. Molecular formula: C3H3N3O2. Mole weight: 113.07.
1,2-Di-O-acetyl-3-azido-3-deoxy-5-O-toluoyl-D-ribofuranose is an intermediate used for synthesizing broad-spectrum antiviral drugs, such as Ribavirin. Synonyms: 1,2-DI-O-ACETYL-3-AZIDO-3-DEOXY-5-O-TOLUOYL-D-RIBOFURANOSE; D-Ribofuranose, 3-azido-3-deoxy-, 1,2-diacetate 5-(4-methylbenzoate); [(2S,3R,4R)-4,5-diacetyloxy-3-azidooxolan-2-yl]methyl 2-methylbenzoate; W-200936. CAS No. 120143-22-8. Molecular formula: C17H19N3O7. Mole weight: 377.35.
1, 3-Dichloro-1, 1, 3, 3-tetraisopropyl disiloxane is used in the analysis of Watson-Crick and Hoogstein base pairing in nucleotides. Also used in the formation of ribavirin chemical delivery systems. Group: Biochemicals. Alternative Names: 1,1,3,3-Tetraisopropyl-1,3-dichlorodisiloxane; 1, 3-Dichloro-1, 1, 3, 3-tetraisopropyl disiloxane; 1, 3-Dichlorotetraisopropyl disiloxane; TIPDS-Cl2; Tetraisopropyl disiloxane-1, 3-diyl Dichloride. Grades: Highly Purified. CAS No. 69304-37-6. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
1,3-O-Benzylidene-L-arabitol
1,3-O-Benzylidene-L-Arabitol, a chemical substance widely employed in the biomedical sector, serves as a fundamental precursor for manufacturing antiviral drugs including Ribavirin. Additionally, its potential as an effective treatment for fungal infections has evinced substantial promise. Its multifarious pharmacological effects and relevance in bioactive therapeutic agents make it an ideal candidate for biomedical research. Synonyms: (1S)-1-[(4S,5S)-5-hydroxy-2-phenyl-1,3-dioxan-4-yl]ethane-1,2-diol; 1,3-O-benzylidene-L-arabitol; (1S)-1-((4S,5S)-5-Hydroxy-2-phenyl-1,3-dioxan-4-yl)ethane-1,2-diol; 53131-06-9. Molecular formula: C12H16O5. Mole weight: 240.26.
1-b-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide methyl ester is an analogue nucleoside operative in antiviral medicaments. It can serve to obstruct the progression of viral ribonucleic acid synthesis, debilitating the replication capacity of particular viruses. Synonyms: Impurity H Ribavirin. CAS No. 38934-69-9. Molecular formula: C9H13N3O6. Mole weight: 259.22.
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone is a key intermediate used in the synthesis of antiviral drugs such as Ribavirin. Synonyms: AK-77581; (3R,4R,5R)-3,4-Bis(benzyloxy)-5-((benzyloxy)methyl)dihydrofuran-2(3H)-one; 2-O,3-O,5-O-Tribenzyl-D-ribonic acid gamma-lactone; 2,3,5-Tri-O-benzyl-D-ribonolactone. Grades: ≥95% by HPLC. CAS No. 55094-52-5. Molecular formula: C26H26O5. Mole weight: 418.48.
Byproduct in the preparation of Ribavirin. Synonyms: 2',3'-O-Isopropylidene-1-β-D-ribofuranosyl-1H-1,2,4-triazole-5-carboxylic Acid Methyl Ester 5'-O-Acetate; Methyl 1-(2',3'-O-Isopropylidene-β-D-ribofuranosyl)-1,2,4-triazole-5-carboxylate 5'-O-Acetate. Molecular formula: C14H19N3O7. Mole weight: 341.32.
2'-Deoxy-2'-fluoroguanosine
It is an influenza viral polymerase inhibitor like Ribavirin, used as an antiviral drug against avian (H5N1) influenza virus. Uses: Antiviral agents. Synonyms: 9-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)guanine; 2'-Fluoro-2'-deoxyguanosine; 2-Amino-9-((2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one; Guanosine, 2'-deoxy-2'-fluoro-; 2'-Fluoro-Riboguanosine. Grades: ≥95%. CAS No. 78842-13-4. Molecular formula: C10H12FN5O4. Mole weight: 285.23.
2'-(O-Allyl)-uridine
2'-(O-Allyl)-uridine is a modified nucleoside often used in research of various viral diseases like Hepatitis C. Acting as a critical component in Ribavirin, it exhibits antiviral activities targeting a broad spectrum of RNA and DNA viruses. Grades: ≥ 98% by HPLC. Molecular formula: C12H16N2O6. Mole weight: 284.27.
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: benzoic acid [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxo-2-oxolanyl]methyl ester; [(2R,3R,4R)-3-benzoyloxy-4-fluoro-4-methyl-5-oxooxolan-2-yl]methyl benzoate. Grades: 99 %. CAS No. 874638-80-9. Molecular formula: C20H17FO6. Mole weight: 372.34.
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: ((2R,3R,4R,5R)-3-(benzoyloxy)-4-chloro-5-(2,4-dioxo-3,4-dihydropyrimidine-1(2H)-yl )-4-methyltetrahydrofuran-2-pyridin-3-yl)methyl benzoate. Grades: 98%. CAS No. 1496551-71-3. Molecular formula: C24H21ClN2O7. Mole weight: 484.89.
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2R,3R,4R,5R)-5-(4-benzoylamino-2-oxopyrimidine-1(2H)-yl)-2-((benzoyloxy)methyl)-4-Chloro-4-methyltetrahydrofuran-3-ylbenzoate. Grades: 95%. CAS No. 1496551-70-2. Molecular formula: C31H26ClN3O7. Mole weight: 588.01.
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: 95%. CAS No. 863329-64-0. Molecular formula: C31H27N3O8. Mole weight: 569.56.
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Propan-2-yl (2S) -2-{[pentafluorophenoxy (phenoxy) phosphoryl]amino}propanoate; N-[ (S) - (2, 3, 4, 5, 6-Pentafluorophenoxy) Phenoxyphosphinyl]-L-Alanine 1-Methylethyl Ester; N-[ (S) - (2, 3, 4, 5, 6-Pentafluorophenoxy) phenoxyphosphinyl]-L-alanine1-methylethyl ester. CAS No. 1256490-52-4. Molecular formula: C18H17F5NO5P. Mole weight: 453.302.
3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose
3-deoxy-1,2-O-isopropylidene-α-D-ribofuranose - a paramount precursor for the synthesis of antiviral agents like Ribavirin and Lamivudine. Its importance spans beyond mere structural composition, its versatility allows for the synthesis of various nucleoside analogues that specifically target viral replication - chiefly in treatment of hepatitis C and HIV. Prevalent in the biomedical industry, its key role is noted for drug development success and biomedical triumphs. Synonyms: 3-deoxy-1,2-O-isopropylidene-α-D-erythro-pentofuranose; ((3aR,5S,6aR)-2,2-dimethyl-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methanol; O1,O2-isopropylidene-α-D-erythro-3-deoxy-pentofuranose; 3-deoxy-1,2-isopropylidene-α-D-ribofuranose; 3-deoxy-1,2-0-isopropylidene-α-D-xylofuranose 3-deoxy-1,2-O-isopropylidee-α-D-ribofuranose. Grades: 98%. CAS No. 3396-71-2. Molecular formula: C8H14O4. Mole weight: 174.194.
Used in the synthesis of enantioselective synthesis of carbocyclic ribavirin, its analogs and other antiviral agents. Group: Biochemicals. Alternative Names: (4R)-3-[((1S,2S)-2-Hydroxy-3-cyclopenten-1-yl)carbonyl]-4-(phenylmethyl)-1,3-oxazolidin-2-one. Grades: Highly Purified. CAS No. 324741-99-3. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
5-Cyano-2'-deoxycytidine
5-Cyano-2'-deoxycytidine, a crucial compound in nucleoside chemistry, holds immense significance within the biomedical industry. Its diverse applications encompass the synthesis of essential antiviral medications like ribavirin and sorivudine. By impeding viral replication, this multifaceted product proves instrumental in combating a range of viral infections including hepatitis C and herpes. CAS No. 1044575-52-1. Molecular formula: C10H12N4O4. Mole weight: 252.23.
Chlorcyclizine hydrochloride
Chlorcyclizine is a phenylpiperazine that acts as a histamine H1 receptor antagonist (Ki = 9 nM). It is believed to be effective against hepatitis C virus (HCV; EC50 = 44 nM in vitro), targeting viral entry into host cells. Chlorcyclizine showed a synergistic effect with other hepatitis C drugs such as ribavirin, interferon, telaprevir, boceprevir, sofosbuvir, daclatasvir, and cyclosporin A. Synonyms: NSC 169496; Chlorcyclizine HCl; 1-[(4-chlorophenyl)phenylmethyl]-4-methyl-piperazine monohydrochloride. Grades: ≥98%. CAS No. 14362-31-3. Molecular formula: C18H21ClN2·HCl. Mole weight: 337.3.
Deleobuvir
Deleobuvir, also known as BI207127, a non-nucleoside hepatitis C virus NS5B polymerase inhibitor for the treatment of hepatitis C. Deleobuvir was tested in combination regimens with pegylated interferon and ribavirin, and in interferon-free regimens with other direct-acting antiviral agents including faldaprevir. Deleobuvir showed that a triple combination of deleobuvir, faldaprevir, and ribavirin performed well in HCV genotype 1b patients. Efficacy fell below 50%, however, for dual regimens without ribavirin and for genotype 1a patients. In December 2013, deleobuvir was discontinued since recent findings from phase III trials did not suggest sufficient efficacy. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BI207127; BI-207127; BI 207127; Deleobuvir; BI-207127NA; BI-207127Na. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 863884-77-9. Molecular formula: C34H33BrN6O3. Mole weight: 653.58. Purity: >98%. IUPACName: (E)-3-(2-(1-(2-(5-bromopyrimidin-2-yl)-3-cyclopentyl-1-methyl-1H-indole-6-carboxamido)cyclobutyl)-1-methyl-1H-benzo[d]imidazol-6-yl)acrylic acid. Canonical SMILES: O=C(O)/C=C/C1=CC=C2N=C(C3(NC(C4=CC5=C(C=C4)C(C6CCCC6)=C(C7=NC=C(Br)C=N7)N5C)=O)CCC3)N(C)C2=C1. Product ID: ACM863884779. Alfa Chemistry ISO 9001:2015 Certified.
Levovirin
Levovirin is a monocyclic L-nucleosides with type 1 cytokine-inducing activity. Levovirin is the L-enantiomer of Ribavirin with similar immunomodulatory activity but does not have direct antiviral activity or hemolytic anemia. Synonyms: 1-β-L-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; ICN 17261; L-Ribavirin. CAS No. 206269-27-4. Molecular formula: C8H12N4O5. Mole weight: 244.2.
MK-5172
Grazoprevir is a hepatitis C virus protease inhibitor developed for the treatment of hepatitis C. It suppresses NS3 and NS4A, which play a role in the virus splitting its polyprotein into the functional virus proteins. Grazoprevir is often used in combination with elbasvir or ribavirin. Uses: Antiviral agents. Synonyms: Cyclopropanecarboxamide, N-[[[ (1R, 2R) -2-[5- (3-hydroxy-6-methoxy-2-quinoxalinyl) pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl- (4R) -4-hydroxy-L-prolyl-1-amino-N- (cyclopropylsulfonyl) -2-ethenyl-, cyclic (1?2)-ether, (1R,2S)-; Grazoprevir; (1R, 2S) -N-[[[ (1R, 2R) -2-[5- (3-Hydroxy-6-methoxy-2-quinoxalinyl) pentyl]cyclopropyl]oxy]carbonyl]-3-methyl-L-valyl- (4R) -4-hydroxy-L-prolyl-1-amino-N- (cyclopropylsulfonyl) -2-ethenylcyclopropanecarboxamide Cyclic (1?2)-Ether. Grades: >98%. CAS No. 1350514-68-9. Molecular formula: C38H50N6O9S. Mole weight: 766.91.
Simeprevir sodium salt
Simeprevir is an orally bioavailable inhibitor of the hepatitis C virus (HCV) NS3/4A protease. It has been approved in combination with peginterferon-alfa and ribavirin for the treatment of HCV and HBV infections. Uses: Antiviral agents. Synonyms: TMC 435 sodium salt; TMC 435 sodium. Grades: ≥98%. CAS No. 1241946-89-3. Molecular formula: C38H47N5O7S2·xNa. Mole weight: 749.94.
Sofosbuvir Impurity 1
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2R,3R,4S,5R)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl Benzoate; N4,3',5'-Tribenzoyl,2'-deoxy-2'β-fluoro-2'C-α-methyl Cytidine. Grades: > 95%. Molecular formula: C31H26FN3O7. Mole weight: 571.55.
Sofosbuvir Impurity 10
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Uridine, 2'-deoxy-2'-methylene-, 3',?5'-dibenzoate. Grades: > 95%. CAS No. 1910099-17-0. Molecular formula: C24H20N2O7. Mole weight: 448.42.
Sofosbuvir Impurity 11
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-epi-Sofosbuvir Desphosphate. Grades: > 95%. Molecular formula: C10H13FN2O5. Mole weight: 260.22.
Sofosbuvir Impurity 12
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-c-methyl arabino-uridine; 1-(2-C-Methyl-β-D-arabinofuranosyl)-2,4(1H,3H)-pyrimidinedione; 1-((2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: > 95%. CAS No. 114262-49-6. Molecular formula: C10H14N2O6. Mole weight: 258.23.
Sofosbuvir Impurity 13
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Methylene-2'-deoxyuridine; 2'-Methylidene-2'-deoxyuridine; 2'-Deoxy-2'-methyleneuridine. Grades: > 95%. CAS No. 119410-95-6. Molecular formula: C10H12N2O5. Mole weight: 240.22.
Sofosbuvir Impurity 14
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 15
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Defluro-2'-hydroxy 2'-epi-Sofosbuvir. Grades: > 95%. Molecular formula: C22H30N3O10P. Mole weight: 527.46.
Sofosbuvir Impurity 16
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: 2'-Defluro-2'-methylene Sofosbuvir. Grades: > 95%. Molecular formula: C22H28N3O9P. Mole weight: 509.45.
Sofosbuvir Impurity 17
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Grades: > 95%. Molecular formula: C34H45FN4O13P2. Mole weight: 798.7.
Sofosbuvir Impurity 2
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Benzamide, N-[1-(3,5-di-O-benzoyl-2-C-methyl-beta-D-arabinofuranosyl)-1,2-dihydro-2-oxo-4-pyrimidinyl]-. Grades: > 95%. CAS No. 863329-62-8. Molecular formula: C31H27N3O8. Mole weight: 569.56.
Sofosbuvir Impurity 20
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: (2S)-Isopropyl 2- ( ( ( ( (2R, 3R, 4R, 5R) -5- (2, 4-Dioxo-3, 4-dihydropyrimidin-1 (2H) -yl) -4-fluoro-2- (hydroxymethyl) -4-methyltetrahydrofuran-3-yl) oxy) (phenoxy) phosphoryl) amino) propanoate; Sofosbuvir 5'-Desphosphate 3'-O-[(S)-Phosphate]. Grades: > 95%. CAS No. 1337482-15-1. Molecular formula: C22H29FN3O9P. Mole weight: 529.46.
Sofosbuvir Impurity 21
An impurity of Sofosbuvir. Sofosbuvir is a NS5B inhibtor used for the treatment of hepatitis C. It is only recommended with some combination of ribavirin, peginterferon-alfa, simeprevir, ledipasvir or daclatasvir. Synonyms: Chloro (R)-Phosphoryl Sofosbuvir. Grades: > 95%. CAS No. 1496552-50-1. Molecular formula: C22H29ClN3O9P. Mole weight: 545.92.
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