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| Product | Description | |
|---|---|---|
| 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase | KsgA introduces the most highly conserved ribosomal RNA modification, the dimethylation of adenine1518 and adenine1519 in 16S rRNA. Strains lacking the methylase are resistant to kasugamycin. Group: Enzymes. Synonyms: S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Enzyme Commission Number: EC 2.1.1.182. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1781; 16S rRNA (adenine1518-N6/adenine1519-N6)-dimethyltransferase; EC 2.1.1.182; S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; KsgA; ksgA methyltransferase. Cat No: EXWM-1781. |  |
| 16S rRNA (guanine527-N7)-methyltransferase | The enzyme specifically methylates guanine527 at N7 in 16S rRNA. Group: Enzymes. Synonyms: ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Enzyme Commission Number: EC 2.1.1.170. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1768; 16S rRNA (guanine527-N7)-methyltransferase; EC 2.1.1.170; ribosomal RNA small subunit methyltransferase G; 16S rRNA methyltransferase RsmG; GidB; rsmG (gene name). Cat No: EXWM-1768. | |
| 16S rRNA pseudouridine516 synthase | The enzyme is specific for uridine516 in 16S rRNA. In vitro, the enzyme does not modify free 16S rRNA. The preferred substrate is a 5'-terminal fragment of 16S rRNA complexed with 30S ribosomal proteins. Group: Enzymes. Synonyms: 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Enzyme Commission Number: EC 5.4.99.19. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5558; 16S rRNA pseudouridine516 synthase; EC 5.4.99.19; 16S RNA pseudouridine516 synthase; 16S PsiI516 synthase; 16S RNA ψ516 synthase; RNA pseudouridine synthase RsuA; RsuA; 16S RNA pseudouridine 516 synthase. Cat No: EXWM-5558. | |
| 23S rRNA (guanine1835-N2)-methyltransferase | The enzyme methylates 23S rRNA in vitro, assembled 50S subunits are not a substrate. The enzyme specifically methylates guanine1835 at N2 in 23S rRNA. Group: Enzymes. Synonyms: ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Enzyme Commission Number: EC 2.1.1.174. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1772; 23S rRNA (guanine1835-N2)-methyltransferase; EC 2.1.1.174; ygjO (gene name); rlmG (gene name); ribosomal RNA large subunit methyltransferase G. Cat No: EXWM-1772. | |
| 23S rRNA (guanine2535-N1)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (guanine2535-N1)-methyltransferase and EC 2.1.1.208 [23S rRNA (uridine2479-2-O)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRa. Enzyme Commission Number: EC 2.1.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1810; 23S rRNA (guanine2535-N1)-methyltransferase; EC 2.1.1.209; AviRa. Cat No: EXWM-1810. | |
| 23S rRNA (guanine745-N1)-methyltransferase | The enzyme specifically methylates guanine745 at N1 in 23S rRNA. Group: Enzymes. Synonyms: Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Enzyme Commission Number: EC 2.1.1.187. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1786; 23S rRNA (guanine745-N1)-methyltransferase; EC 2.1.1.187; Rlma(I); Rlma1; 23S rRNA m1G745 methyltransferase; YebH; RlmAI methyltransferase; ribosomal RNA(m1G)-methylase (ambiguous); rRNA(m1G)methylase (ambiguous); RrmA (ambiguous); 23S rRNA:m1G745 methyltransferase. Cat No: EXWM-1786. | |
| 23S rRNA (uridine2479-2'-O)-methyltransferase | Streptomyces viridochromogenes produces the antibiotic avilamycin A which binds to the 50S ribosomal subunit to inhibit protein synthesis. To protect itself from the antibiotic, Streptomyces viridochromogenes utilizes two methyltransferases, 23S rRNA (uridine2479-2'-O)-methyltransferase and EC 2.1.1.209 [23S rRNA (guanine2535-N1)-methyltransferase], whose actions confer avilamycin resistance to the RNA. Group: Enzymes. Synonyms: AviRb. Enzyme Commission Number: EC 2.1.1.208. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1809; 23S rRNA (uridine2479-2'-O)-methyltransferase; EC 2.1.1.208; AviRb. Cat No: EXWM-1809. | |
| 23S rRNA (uridine2552-2'-O)-methyltransferase | The enzyme catalyses the 2'-O-methylation of the universally conserved U2552 in the A loop of 23S rRNA. Group: Enzymes. Synonyms: Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Enzyme Commission Number: EC 2.1.1.166. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1763; 23S rRNA (uridine2552-2'-O)-methyltransferase; EC 2.1.1.166; Um(2552) 23S ribosomal RNA methyltransferase; heat shock protein RrmJ; RrmJ; FTSJ; Um2552 methyltransferase. Cat No: EXWM-1763. | |
| 2',5-Difluoro-2'-deoxycytidine | 2',5-Difluoro-2'-deoxycytidine has potent activity against HCV and toxicity to ribosomal RNA (rRNA). Synonyms: 2'-deoxy-2',5-difluorocytidine; Cytidine, 2'-deoxy-2',5-difluoro-; 4-amino-5-fluoro-1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one. Grade: ≥95%. CAS No. 581772-30-7. Molecular formula: C9H11F2N3O4. Mole weight: 263.20. |  |
| 25S rRNA (cytosine2870-C5)-methyltransferase | The enzyme, found in eukaryotes, is specific for cytosine2870 of the 25S ribosomal RNA. The numbering corresponds to the enzyme from the yeast Saccharomyces cerevisiae. Group: Enzymes. Synonyms: NOP2 (gene name). Enzyme Commission Number: EC 2.1.1.310. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1918; 25S rRNA (cytosine2870-C5)-methyltransferase; EC 2.1.1.310; NOP2 (gene name). Cat No: EXWM-1918. | |
| 2'-O-MethylpseudoUridine-5'-Triphosphate Lithium | 2'-O-MethylpseudoUridine-5'-Triphosphate Lithium is a nucleotide analog commonly used in molecular biology research to investigate RNA modification and translation. It has been shown to enhance ribosomal reading efficiency and suppress frameshifting during translation. It may also play a role in regulating immune function and has potential therapeutic applications in autoimmunity and inflammatory diseases. Synonyms: 2'-O-Methylpseudo-UTP tetralithium salt. Grade: ≥90% by AX-HPLC. Molecular formula: C10H13Li4N2O15P3. Mole weight: 521.89. | |
| 5-Fluorocytidine | 5-Fluorocytidine is a member of cytidines, inhibits maturation of the 45S ribosomal RNA precursor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2341-22-2. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg; 1 g. Product ID: HY-W039722. |  |
| 7-Propargylamino-7-deaza-ddATP - ATTO-425 | 7-Propargylamino-7-deaza-ddATP - ATTO-425 is a fluorescent nucleotide analog extensively used in biomedical research for labeling and detecting DNA fibers dynamics. It has been employed to study the molecular basis of DNA replications, identifying remotely induced mutations, and studying ribosomal RNA transcription, amongst other applications. Synonyms: 7-Deaza-7-propargylamino-2',3'-dideoxyadenosine-5'-triphosphate, labeled with ATTO 425, Triethylammonium salt. Grade: ≥ 95% by HPLC. Molecular formula: C36H45N6O16P3 (free acid). Mole weight: 910.70 (free acid). | |
| BMH-21 | BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. Uses: Enzyme inhibitors. Synonyms: BMH-21; BMH 21; BMH21. Grade: >98%. CAS No. 896705-16-1. Molecular formula: C21H22N4O2. Mole weight: 362.43. | |
| Erythromycin | Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research [3][4]. Uses: Scientific research. Group: Natural products. CAS No. 114-07-8. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0220. | |
| Erythromycin | Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research. Uses: Designed for use in research and industrial production. Additional or Alternative Names: abboticin;abomacetin;dotycin;em;emu;e-mycin;erycin;erycinum. Product Category: Inhibitors. Appearance: powder. CAS No. 114-07-8. Molecular formula: C37H67NO13. Mole weight: 733.93. Purity: 0.9986. Product ID: ACM114078. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Erythromycin a dihydrate | Erythromycin A dihydrate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin A dihydrate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin A dihydrate also exhibits antitumor and neuroprotective effect in different fields of research. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 59319-72-1. Molecular formula: C37H67NO13.H2O. Mole weight: 751.945. Product ID: ACM59319721. Alfa Chemistry ISO 9001:2015 Certified. Categories: Erythromycin dihydrate. | |
| Erythromycin-d3 | Erythromycin-d3 is the deuterium labeled Erythromycin[1]. Erythromycin is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin also exhibits antitumor and neuroprotective effect in different fields of research[2][3][4][5]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 959119-26-7. Pack Sizes: 1 mg. Product ID: HY-B0220S2. | |
| Erythromycin lactobionate | Erythromycin lactobionate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin lactobionate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid. Erythromycin lactobionate also exhibits antitumor and neuroprotective effect in different fields of research. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Erythromycin lactobionate;Erythromycin lactobionate (200 mg). Product Category: Inhibitors. Appearance: White to off-white powder. CAS No. 3847-29-8. Molecular formula: C37H67NO13.C12H22O12. Mole weight: 1092.22. Purity: 0.98. Density: g/cm³. Product ID: ACM3847298. Alfa Chemistry ISO 9001:2015 Certified. | |
| Erythromycin thiocyanate | Erythromycin thiocyanate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin thiocyanate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid [1][2]. Erythromycin thiocyanate also exhibits antitumor and neuroprotective effect in different fields of research [3][4]. Uses: Scientific research. Group: Natural products. CAS No. 7704-67-8. Pack Sizes: 10 mM * 1 mL; 1 g; 5 g. Product ID: HY-B0220D. | |
| (Gly14)-Humanin (human) | (Gly14)-Humanin (human) is an analog of Humanin. Humanin is a micropeptide encoded by the 16S ribosomal RNA gene MT-RNR2 in the mitochondrial genome. Synonyms: H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH. CAS No. 330936-70-4. Molecular formula: C118H202N34O31S2. Mole weight: 2657.21. | |
| Humanin (human) (trifluoroacetate salt) | Humanin is a micropeptide encoded by the 16S ribosomal RNA gene MT-RNR2 in the mitochondrial genome. Synonyms: H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH.TFA; L-methionyl-L-alanyl-L-prolyl-L-arginyl-glycyl-L-phenylalanyl-L-seryl-L-cysteinyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-alpha-aspartyl-L-leucyl-L-prolyl-L-valyl-L-lysyl-L-arginyl-L-arginyl-L-alanine trifluoroacetic acid. Grade: 95%. Molecular formula: C121H205F3N34O34S2. Mole weight: 2801.3. | |
| Linezolid | Linezolid is an organofluorine compound that consists of 1,3-oxazolidin-2-one bearing an N-3-fluoro-4-(morpholin-4-yl)phenyl group as well as an acetamidomethyl group at position 5. A synthetic antibacterial agent that inhibits bacterial protein synthesis by binding to a site on 23S ribosomal RNA of the 50S subunit and prevents further formation of a functional 70S initiation complex. It has a role as an antibacterial drug and a protein synthesis inhibitor. It is an oxazolidinone, a member of morpholines, an organofluorine compound and a member of acetamides. CAS No. 165800-03-3. Product ID: PAP-0042. Molecular formula: C16H20FN3O4. Category: Antibacterial, anti-inflammatory and antiviral. Product Keywords: Antibacterial, Anti-inflammatory and Antiviral Series; Linezolid; PAP-0042; Antibacterial, anti-inflammatory and antiviral; C16H20FN3O4; 165800-03-3. Standard: Internal Control/USP. Color: white to off-white. EC Number: 605-416-1. Physical State: powder. Solubility: DMSO: >20mg/mL. Storage: room temp. Applications: Linezolid is an antibiotic used for the treatment of infections caused by Gram-positive bacteria that are resistant to other antibiotics. Linezolid is active against most Gram-positive bacteria that cause disease, including streptococci, vancomycin-resistant enterococci (VRE), and methicillin-resistant Staphylococcus aureus (MRSA). Boiling Point: 585.5±50.0 °C(Predicted). Melting Point: 176-178°C. Density: 1 |  |
| Metalaxyl-M | Metalaxyl-M ((R)-Metalaxyl) is the active (R)-enantiomer of Metalaxyl. Metalaxyl-M is a broad-spectrum fungicide that inhibits protein and ribosomal RNA synthesis in fungi. Metalaxyl is used for research of plant diseases caused by pathogens of the Oomycota division [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: (R)-Metalaxyl. CAS No. 70630-17-0. Pack Sizes: 10 mM * 1 mL; 10 mg; 50 mg; 100 mg. Product ID: HY-B0843A. | |
| Oxytetracycline | Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti- HSV-1 activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 79-57-2. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0275. | |
| Oxytetracycline calcium | Oxytetracycline calcium is an antibiotic belonging to the tetracycline class. Oxytetracycline calcium potently inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline calcium is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline calcium also possesses anti-HSV-1 activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, calcium salt (1:1), (4S-(4-alpha,4a-alpha,5-alpha,5a-alpha,6-beta,12a-alpha))-. Product Category: Inhibitors. CAS No. 7179-50-2. Molecular formula: C22H22CaN2O9. Mole weight: 498.5. Product ID: ACM7179502-1. Alfa Chemistry ISO 9001:2015 Certified. | |
| Oxytetracycline dihydrate | Oxytetracycline dihydrate is an antibiotic belonging to the tetracycline class. Oxytetracycline dihydrate potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline dihydrate is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline dihydrate also possesses anti-HSV-1 activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-, (4S-(4alpha,4aalpha,5alpha,5aalpha,6beta,12aalpha))-, dihydrate;Terramycin dihydrate. Product Category: Inhibitors. CAS No. 6153-64-6. Molecular formula: C22H28N2O11. Mole weight: 496.46. Product ID: ACM6153646. Alfa Chemistry ISO 9001:2015 Certified. | |
| Oxytetracycline hydrochloride | Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti- HSV-1 activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2058-46-0. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0275A. | |
| Oxytetracycline hydrochloride | Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity. Uses: Designed for use in research and industrial production. Additional or Alternative Names: terramycin hydrochloride; GEOMYCIN; Oxycline; engemycin; mepatar; TOXINAL; oxytetracycline HCl; (4S,4aR,5S,5aR,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide hydrochloride; (4S,4aR,5S,5aR,6S,12aS)-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hydrochloride (1:1); oxlopar; oxytetracyclin hydrochloride; OTC; Oxytetracycline Hydrochloride; otetryn; Oxytetracycline Hydrochloride,Can be Used as Secondary Standard; Oxytetracycline hydrochloride; tm5. Product Category: Inhibitors. Appearance: yellow crystalline powder. CAS No. 2058-46-0. Molecular formula: C22H24N2O9·HCl. Mole weight: 496.89. Purity: 95%+. IUPACName: oxytetracycline hydrochloride. Density: 1.71 g/cm³. Product ID: ACM2058460. Alfa Chemistry ISO 9001:2015 Certified. | |
| Oxytetracycline (hydrochloride) (Standard) | Oxytetracycline (hydrochloride) (Standard) is the analytical standard of Oxytetracycline (hydrochloride). This product is intended for research and analytical applications. Oxytetracycline hydrochloride is an antibiotic belonging to the tetracycline class. Oxytetracycline hydrochloride potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline hydrochloride is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline hydrochloride also possesses anti-HSV-1 activity [1] [2] [3]. Uses: Scientific research. Group: Natural products. CAS No. 2058-46-0. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0275AR. | |
| Poly(A) polymerase gamma (724-734) | Poly(A) polymerase gamma (724-734) is a peptide corresponding to residues 724-734 of Poly(A) polymerase gamma. Poly(A) polymerase gamma is responsible for the post-transcriptional adenylation of the 3'-terminal of mRNA precursors and several small RNAs including signal recognition particle (SRP) RNA, nuclear 7SK RNA, U2 small nuclear RNA, and ribosomal 5S RNA. Synonyms: PAP-gamma (724-734); Polynucleotide adenylyltransferase gamma (724-734); Signal recognition particle RNA-adenylating enzyme (724-734). | |
| Quarfloxin | Quarfloxin (CX-3543), a fluoroquinolone derivative with antineoplastic activity, targets and inhibits RNA pol I activity, with IC 50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA (rDNA) template [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CX-3543. CAS No. 865311-47-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14776. | |
| ribonuclease E | RNase E is a bacterial ribonuclease that plays a role in the processing of ribosomal RNA (9S to 5S rRNA), the chemical degradation of bulk cellular RNA, the decay of specific regulatory, messenger and structural RNAs and the control of plasmid DNA replication. The enzyme binds to monophosphorylated 5' ends of substrates but exhibits sequential cleavages in the 3' to 5' direction. 2'-O-Methyl nucleotide substitutions at RNase E binding sites do not prevent binding but do prevent cleavage of non-modified target sequences 5' to that locus. In Escherichia coli, the enzyme is found in the RNA degradosome. The C-terminal half of the protein contains binding sites for the three other major degradosomal components, the DEAD-box RNA helicase Rh1B, enolase (EC 4.1.1.11) and polynucleotide phosphorylase (EC 2.7.7.8). Group: Enzymes. Synonyms: endoribonuclease E; RNase E; Rne protein. Enzyme Commission Number: EC 3.1.26.12. CAS No. 76106-82-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3588; ribonuclease E; EC 3.1.26.12; 76106-82-6; endoribonuclease E; RNase E; Rne protein. Cat No: EXWM-3588. | |
| ribonuclease M5 | Converts the 5S-rRNA precursor from Bacillus subtilis into 5S-rRNA, with 5'-phosphate and 3'-hydroxy groups. Group: Enzymes. Synonyms: RNase M5; 5S ribosomal maturation nuclease; 5S ribosomal RNA maturation endonuclease. Enzyme Commission Number: EC 3.1.26.8. CAS No. 62253-00-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3596; ribonuclease M5; EC 3.1.26.8; 62253-00-3; RNase M5; 5S ribosomal maturation nuclease; 5S ribosomal RNA maturation endonuclease. Cat No: EXWM-3596. | |
| rRNA N-glycosylase | Ricin A-chain and related toxins show this activity. Naked rRNA is attacked more slowly than rRNA in intact ribosomes. Naked rRNA from Escherichia coli is cleaved at a corresponding position. Group: Enzymes. Synonyms: ribosomal ribonucleate N-glycosidase; nigrin b; RNA N-glycosidase; rRNA N-glycosidase; ricin; momorcochin-S; Mirabilis antiviral protein; momorcochin-S; gelonin; saporins. Enzyme Commission Number: EC 3.2.2.22. CAS No. 113756-12-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3976; rRNA N-glycosylase; EC 3.2.2.22; 113756-12-0; ribosomal ribonucleate N-glycosidase; nigrin b; RNA N-glycosidase; rRNA N-glycosidase; ricin; momorcochin-S; Mirabilis antiviral protein; momorcochin-S; gelonin; saporins. Cat No: EXWM-3976. | |
| rRNA small subunit pseudouridine methyltransferase Nep1 | This enzyme, which occurs in both prokaryotes and eukaryotes, recognizes specific pseudouridine residues (ψ) in small subunits of ribosomal RNA based on the local RNA structure. It recognizes ψ914 in 16S rRNA from the archaeon Methanocaldococcus jannaschii, ψ1191 in yeast 18S rRNA, and ψ1248 in human 18S rRNA. Group: Enzymes. Synonyms: Nep1; nucleolar essential protein 1. Enzyme Commission Number: EC 2.1.1.260. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1865; rRNA small subunit pseudouridine methyltransferase Nep1; EC 2.1.1.260; Nep1; nucleolar essential protein 1. Cat No: EXWM-1865. | |
| Tedizolid | Tedizolid (TR 700; Torezolid; DA-7157) is a novel oxazolidinone, acting through inhibition of bacterial protein synthesis by binding to 23S ribosomal RNA (rRNA) of the 50S subunit of the ribosome. Uses: Scientific research. Group: Signaling pathways. Alternative Names: TR 700; Torezolid; DA-7157. CAS No. 856866-72-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14855. | |
| 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) | 1,2-dioleoyl-3-trimethylammonium-propane (methyl sulfate salt) is a liposome formulation for cationic lipid DOTAP. DOTAP can be used for the efficiency of DNA transfection, including yeast artificial chromosomes (YAC) transfection to eukaryotic cells used in transient or stable gene expression, and also suitable for efficient will other negatively charged molecules, such as RNA, oligonucleotides, and glutamic acid, the ribosome protein (RNP) complex, and protein, transferred to the study sample of mammalian cells. Synonyms: DOTAP Transfection Reagent; DOTAP-MS; N,N,N-Trimethyl-2,3-bis(oleoyloxy)propan-1-aminium methyl sulfate; DOTAP methosulfate; 18:1 TAP (DOTAP, MS Salt); n-(2,3-dioleoyloxy-1-propyl) trimethylammonium methyl sulfate. Grade: 98%. CAS No. 144189-73-1. Molecular formula: C43H83NO8S. Mole weight: 774.19. | |
| 2,2'-Anhydrouridine | 2,2'-Anhydrouridine is a modified nucleoside that lacks a hydroxyl group at the 2' position of the ribose ring. It is commonly found in transfer RNA (tRNA) and plays a role in stabilizing the tRNA structure. This modification is important for proper tRNA function as it helps maintain the overall stability and folding of the molecule. 2,2'-Anhydrouridine is also known to be involved in the recognition and binding of tRNA to the ribosome during protein synthesis. Synonyms: 2,2'-Anhydro-b-D-arabinofuranosyl uracil; O-2,2'-Cyclouridine; 2,2'-Anhydro-D-uridine; 2,2'-Anhydro Uridine; (2R,3R,3aS,9aR)-2,3,3a,9a-Tetrahydro-3-hydroxy-2-(hydroxymethyl)-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-on; 6H-Furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one, 2,3,3a,9a-tetrahydro-3-hydroxy-2-(hydroxymethyl)-, [2R-(2α,3β,3aβ,9aβ)]-; 2,2'-Anhydro(1-β-D-arabinofuranosyl)uracil; 2,2'-Anhydro-N1-(β-D-arabinofuranosyl)uracil; 2,2'-Anhydrouridine; 2,2'-O-Cyclouridine; NSC 157148; O2,2'-Anhydrouridine; O2,2'-Cyclouridine; β-D-2',2-O-Cycloarabinouridine. Grade: ≥95%. CAS No. 3736-77-4. Molecular formula: C9H10N2O5. Mole weight: 226.19. | |
| 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase | Spb1p is a site-specific 2'-O-ribose RNA methyltransferase that catalyses the formation of 2'-O-methylguanosine2922, a universally conserved position of the catalytic center of the ribosome that is essential for translation. 2'-O-Methylguanosine2922 is formed at a later stage of the processing, during the maturation of of the 27S pre-rRNA. In absence of snR52, Spb1p can also catalyse the formation of uridine2921. Group: Enzymes. Synonyms: Spb1p (gene name); YCL054W (gene name). Enzyme Commission Number: EC 2.1.1.167. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1764; 27S pre-rRNA (guanosine2922-2'-O)-methyltransferase; EC 2.1.1.167; Spb1p (gene name); YCL054W (gene name). Cat No: EXWM-1764. | |
| MYC-RIBOTAC | MYC-RIBOTAC is a nucleic acid-targeting degrader (ribonuclease-targeting chimera, RIBOTAC) that targets the MYC internal ribosome entry site (IRES). MYC-RIBOTAC contains a MYC mRNA binding component and a small molecule that recruits and locally activates RNAse L1. MYC-RIBOTAC reduces MYC mRNA and protein expression levels, induces cell apoptosis, and can be used for antitumor research[1]. MYC-RIBOTAC consists of pre-miR-155 binder Anticancer agent 167 (HY-156839), RNA binder NCI-B16 (HY-156215), and Linker Amino-PEG4-alcohol (HY-W008005). Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-153713. | |
| Paromomycin sulfate | Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: Aminosidine sulfate. CAS No. 1263-89-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g. Product ID: HY-B0956. | |
| Paromomycin Sulfate | Paromomycin (Aminosidine) sulfate, a neomycin (HY-B0470) derivative, is a broad spectrum aminoglycoside antibiotic with amebicidal and bactericidal effects. Paromomycin sulfate prematures termination of translation of mRNA and inhibits protein synthesis by specifically binds to the RNA oligonucleotide at the A site of bacterial 30S ribosomes. Paromomycin sulfate can be used for the research of bacterial and parasitic infections. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Paromomycin sulfate salt. Product Category: Inhibitors. CAS No. 1263-89-4. Molecular formula: C23H47N5O18S. Mole weight: 713.7. Purity: ≥98.0%. Product ID: ACM1263894. Alfa Chemistry ISO 9001:2015 Certified. | |
| Pseudouridine | Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Natural products. CAS No. 1445-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113061. | |
| Spectinomycin dihydrochloride | Spectinomycin dihydrochloride is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride is also a noncompetitive inhibitor of td intron RNA with an K i value of 7.2 mM [1] - [5]. Uses: Scientific research. Group: Natural products. CAS No. 21736-83-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g; 25 g. Product ID: HY-B0438. | |
| Spectinomycin dihydrochloride pentahydrate | Spectinomycin dihydrochloride pentahydrate is a broad-spectrum antibiotic and inhibits the growth of a variety of gram-positive and gram-negative organisms. Spectinomycin dihydrochloride pentahydrate acts by selectively targeting to the bacterial ribosome and interrupting protein synthesis. Spectinomycin dihydrochloride pentahydrate is also a noncompetitive inhibitor of td intron RNA with an K i value of 7.2 mM [1] - [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Spectinomycin hydrochloride hydrate. CAS No. 22189-32-8. Pack Sizes: 10 mM * 1 mL; 500 mg. Product ID: HY-B1828A. | |
| Toyocamycin | Toyocamycin (Vengicide) is an adenosine analog produced by Streptomyces diastatochromogenes, acts as an XBP1 inhibitor. Toyocamycin blocks RNA synthesis and ribosome function, and induces apoptosis. Toyocamycin affects IRE1?-XBP1 pathway, and inhibits XBP1 mRNA cleavage with an IC50 value of 80 nM with affecting IRE1? auto-phosphorylation. Toyocamycin specifically inhibits CDK9 with an IC50 value of 79 nM[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Vengicide. CAS No. 606-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103248. | |
| UAU | UAU (UpApU) is a trinucleotide that is identified as the RNA codon for tyrosine, which is involved in protein synthesis. UAU can be used in research about the interaction between RNA codons, tRNAs, and ribosomes [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UpApU. CAS No. 752-71-6. Pack Sizes: 1 mg. Product ID: HY-159807. | |
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