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Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Synonyms: SR141716; SR 141716; SR-141716. Grades: >98%. CAS No. 168273-06-1. Molecular formula: C22H21Cl3N4O. Mole weight: 463.79.
Rimonabant
Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a K i of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR141716. CAS No. 168273-06-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14136.
Rimonabant-d10
A labeled anorectic antiobesity drug. The drug has been pulled from the marked due to potentially serious side effects. An inverse agonist for the cannabinoid receptor CB1. Reduces appetite. May help assist smoker to quit smoking and possibly other addictions. Blocks the psychoactive and cardiovascular effects of THC. Group: 2h labeled compounds. Alternative Names: Acomplia-d10; SR 141716A-d10; SR 151716A-d10. CAS No. 929221-88-5. Molecular formula: C22H11D10Cl3N4O. Mole weight: 473.95. Catalog: ACM929221885.
Rimonabant Hydrochloride
Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an K i of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SR 141716A Hydrochloride. CAS No. 158681-13-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-14137.
Rimonabant Hydrochloride
Rimonabant Hydrochloride, used as a tool to investigate CB receptor properties, it is a selective antagonist of cannabinoid CB1 receptor (Ki = 1.98 nM) and inverses adenylyl cyclase inhibition (IC50 = 48 nM). Uses: A brain cannabinoid receptor (cb1) antagonist. antiobesity agent. Synonyms: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; Rimonabant free base, SR141716; SR 141716; SR-141716; A 281; A-281; A281; Rimonabant, Acomplia, Zimulti. Grades: 98%. CAS No. 158681-13-1. Molecular formula: C22H21Cl3N4O.HCl. Mole weight: 500.25.
Rimonabant Hydrochloride
The first of a new class of selective (Cannabinoid-1 (CB-1) receptor antagonists. Group: Biochemicals. Alternative Names: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide hydrochloride. Grades: Highly Purified. CAS No. 158681-13-1. Pack Sizes: 10mg. US Biological Life Sciences.
5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methylpyrazole-3-carboxylic Acid is used in the preparation of biarylpyrazole based derivatives as cannabinoid CB1 receptor antagonists. It is metabolite M9 of Rimonabant , an antiobesity agent. Group: Biochemicals. Alternative Names: 1-(2,4-Dichlorophenyl)-5-(4-chlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid; 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxylic Acid. Grades: Highly Purified. CAS No. 162758-35-2. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Otenabant (CP-945,598)
Otenabant, also known as CP-945,598, is a drug which acts as a potent and highly selective CB1 antagonist. It was developed by Pfizer for the treatment of obesity, but development for this application has been discontinued following the problems seen during clinical use of the similar drug rimonabant. Synonyms: Otenabant; CP-945,598; CP-945598; CP 945598; CP945598. Grades: 0.99. CAS No. 686344-29-6. Molecular formula: C25H25Cl2N7O. Mole weight: 510.423.
Otenabant HCl
Otenabant, also known as CP-945,598, is a drug which acts as a potent and highly selective CB1 antagonist. It was developed by Pfizer for the treatment of obesity, but development for this application has been discontinued following the problems seen during clinical use of the similar drug rimonabant. (source: http://en. wikipedia. org/wiki/Otenabant). Group: Antagonists. Alternative Names: CP945598; CP-945598; CP 945598; CP945,598; CP-945,598; CP 945,598; Otenabant HCl. CAS No. 686347-12-6. Molecular formula: C25H26Cl3N7O. Mole weight: 546.88. Appearance: White solid powder. Purity: >98%. IUPACName: 1-(8-(2-chlorophenyl)-9-(4-chlorophenyl)-9H-purin-6-yl)-4-(ethylamino)piperidine-4-carboxamide hydrochloride. Canonical SMILES: O=C (C1 (NCC)CCN (C2=C3N=C (C4=CC=CC=C4Cl)N (C5=CC=C (Cl)C=C5)C3=NC=N2)CC1)N. [H]Cl. Catalog: ACM686347126.
Rosonabant
Rosonabant is a CB1 receptor antagonist/inverse agonist originated by Esteve. It is an appetite suppressant for the treatment of obesity. But development of the drug for clinical use was apparently halted shortly after the related CB1 antagonist rimonabant was discontinued. Uses: Obesity. Synonyms: E-6776; E 6776; E6776; Rosonabant; (R)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-N-(piperidin-1-yl)-4,5-dihydro-1H-pyrazole-3-carboxamide. Grades: 98%. CAS No. 861151-12-4. Molecular formula: C21H21Cl3N4O. Mole weight: 451.78.
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