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| Product | Description | |
|---|---|---|
| Rk-682 | Rk-682. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RK-682;RK-682, STREPTOMYCES SPECIES;3-HEXADECANOYL-5-HYDROXYMETHYL-TETRONIC ACID;ANTIBIOTIC RK-682;ANTIBIOTIC TAN 1364B. Product Category: Heterocyclic Organic Compound. Appearance: Pale yellow solid. CAS No. 154639-24-4. Molecular formula: C21H36O5. Mole weight: 368.51. Purity: ≥98%. IUPACName: RK-682. Product ID: ACM154639244. Alfa Chemistry ISO 9001:2015 Certified. Categories: RK 62. |  |
| RK-682 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| RK-682 | RK-682 is the inhibitor for protein tyrosine phosphatase ( PTPase ), heparanase , phospholipase A2 and HIV-1 protease. RK-682 inhibits the dephosphorylation of CD45 ( IC 50 is 54 μM) and VHR ( IC 50 is 2.0 μM), and thereby inhibits the ERK signaling pathway. RK-682 inhibits the cell viability of cancer cell MGH-U3, T24 and UROtsa with IC 50 s of 78.2, 43.2 and 145 nM, respectively, arrests the cell cycle at G1/S phase, inhibits the cell migration and autophagy in MGH-U3 and T24 [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 150627-37-5. Pack Sizes: 200 μg. Product ID: HY-135564A. |  |
| RK-682 calcium salt | It is a dimeric calcium complex of the major analogue of tetronic acid complex isolated from streptomyces. It inhibits protein tyrosine phosphatases, phospoholipase A2, heparinase and HIV-1 protease. Synonyms: TAN 1364B; CI 010; Calcium bis[(R)-2-oxo-3-hexadecanoyl-5-(hydroxymethyl)-2,5-dihydrofuran-4-olate]; (5R)-4-hydroxy-5-(hydroxymethyl)-3-(1-oxohexadecyl)-2(5H)-furanone, calcium salt (2:1); RK-682 calcium salt (2:1). Grades: >95% by HPLC. CAS No. 332131-32-5. Molecular formula: C42H70CaO10. Mole weight: 775.09. |  |
| Antibiotic RK-682 (Antibiotic TAN 1364B, Antibiotic CI 010) | Antibiotic RK-682 is the calcium salt of one of a complex family of tetronic acids isolated from Streptomyces species. The formation of the salt is almost certainly an artefact of silica chromatography. RK-682 is the most extensively studied of the analogues, having been shown to inhibit protein tyrosine phosphatases and heparanase. Pharmacological studies with RK-682 demonstrated enhanced ATP-induced long-term potentiation using guinea-pig hippocampal slices. Investigation of the complex has also shown potent activity against HIV-1 protease. Group: Biochemicals. Alternative Names: Antibiotic TAN 1364B, Antibiotic CI 010. Grades: Highly Purified. CAS No. 154639-24-4(TAN1364B). Pack Sizes: 500ug. US Biological Life Sciences. |  Worldwide |
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