Find where to buy products from suppliers in the USA, including: distributors, industrial manufacturers in America, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the American suppliers website for prices, SDS or more information. You can also view suppliers in Australia, NZ or the UK.
| Product | Description | |
|---|---|---|
| RN 1747 | RN 1747, a selective TRPV4 agonist (EC50= 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively), represents the first drug-like TRPV4 antagonist with selectivity over closely related TRP channels. The activities of these compounds were characterized using two different systems: Ca2+ influx assay with human, mouse and rat TRPV4-expressing HEK293 cells and electrophysiology in hTRPV4-transfected Xenopus oocytes. Importantly, RN-1734 antagonized both ligand-gated activation and hypotonicity-induced opening of TRPV4 in both types of assay. Synonyms: Piperazine, 1-[(4-chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)-; 1-[(4-Chloro-2-nitrophenyl)sulfonyl]-4-(phenylmethyl)piperazine; RN1747; RN-1747; 1-(4-Chloro-2-nitrophenyl)sulfonyl-4-benzylpiperazine. Grades: ≥95%. CAS No. 1024448-59-6. Molecular formula: C17H18ClN3O4S. Mole weight: 395.87. |  |
| RN 1747 | RN 1747. Group: Biochemicals. Grades: Purified. CAS No. 1024448-59-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| Kanglemycin A | Kanglemycin A (KglA) is related to rifampicin, an antibiotic that functions by binding to bacterial RNA polymerase. KglA binds bacterial RNA polymerase at the rifampicin-binding pocket but maintains potency against RNA polymerases containing rifampicin-resistant mutations. KglA has antibiotic activity against rifampicin-resistant Gram-positive bacteria and multidrug-resistant Mycobacterium tuberculosis. Synonyms: Antibiotic 1747; Rifamycin, 20-(1-(3-carboxy-2,2-dimethyl-1-oxopropoxy)ethyl)-20-demethyl-27-O-demethyl-1,4-dideoxy-27-O-(2,6-dideoxy-3,4-O-methylene-beta-D-ribo-hexopyranosyl)-1,4-dihydro-1,4-dioxo-; Kanglemeisu A; KglA. CAS No. 114153-91-2. Molecular formula: C50H63NO19. Mole weight: 982.03. | |
Our database is helping our users find suppliers everyday.
