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RO-3 RO-3. Group: Biochemicals. Grades: Purified. CAS No. 1026582-88-6. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 5
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RO-3 RO-3 is a potent, CNS-penetrant, and orally active P2X 3 and P2X 2/3 antagonist with pIC 50 s of 5.9 and 7.0 for human homomultimeric P2X 3 and heteromultimeric P2X 2/3 receptors, respectively. RO-3 shows selectivity for P2X 3 and P2X 2/3 over all other functional homomultimeric P2X receptors (IC 50 >10 μM at P2X 1,2,4,5,7 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1026582-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19978. MedChemExpress MCE
RO-3 RO-3 is a selective homomeric P2X3 and heteromeric P2X2/3 receptor antagonist (pIC50 values are 7.0 and 5.9 respectively). RO-3 is used in a combination of compounds to develop a substance used for alleviating pain and skin disorders. Synonyms: 5-[[4,5-Dimethoxy-2-(methylethyl)phenyl]methyl]-2,4-pyrimidinediamine; RO-3; RO 3; RO3. Grades: ≥98% by HPLC. CAS No. 1026582-88-6. Molecular formula: C16H22N4O2. Mole weight: 302.37. BOC Sciences 10
Ro-31-7549, Monohydrate - CAS 125313-65-7 A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC?? = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Ro-31-8220 - CAS 138489-18-6 A cell-permeable, reversible, competitive, and selective inhibitor of protein kinase C (PKC; IC?? = 10 nM) over CaM kinase II (IC?? = 17 μM) and protein kinase A (IC?? = 900 nM). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
Ro-31-8425 - CAS 131848-97-0 A potent, cell-permeable, reversible, ATP-competitive, and selective protein kinase C inhibitor (IC?? = 15 nM for rat brain PKC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
Ro-32-0432 - CAS 145333-02-4 A selective cell-permeable protein kinase C inhibitor. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
RO-3306 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
RO-3306 RO-3306 is a CDK1 inhibitor with potential anticancer activity. Treatment of growing AML cells with RO-3306 induced G2/M-phase cell cycle arrest and apoptosis in a dose- and time-dependent manner. RO-3306 downregulated expression of the antiapoptotic proteins Bcl-2 and survivin and blocked p53-mediated induction of p21 and MDM2. RO-3306 actively enhances downstream p53 signaling to promote apoptosis. Synonyms: RO-3306; RO 3306; RO3306. Grades: 0.98. CAS No. 872573-93-8. Molecular formula: C18H13N3OS2. Mole weight: 351.44. BOC Sciences 10
RO-3306 Selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Potential anti-cancer compound. Cell cycle arrest inducer at G1, S and G2/M. Apoptosis inducer in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines. Suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Enhances Fas-mediated activation and processing of procaspase-8 in mitotic cells towards. Group: Biochemicals. Alternative Names: (5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one. Grades: Highly Purified. CAS No. 872573-93-8. Pack Sizes: 1mg, 5mg. Molecular Formula: C??H??N?OS?. US Biological Life Sciences. USBiological 3
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RO-3306, CDK 1 Inhibitor ((5Z)-2-((Thiophen-2-yl)methylamino)-5-((quinolin-6-yl)methylene)thiazol-4(5H)-one) Cell-permeable. A selective CDK 1 inhibitor (Cdk1/B1 and Cdk1/A). Arrests cell cycle at G1, S, and G2/M and induces apoptosis in embryonic stem cells. Actively enhances downstream p53 signaling to promote apoptosis in AML cell lines, and suppresses phosphorylation of p53 at Ser315 and procaspase-8 at Ser387. Group: Biochemicals. Grades: Highly Purified. CAS No. 872573-93-8. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 3
Worldwide
Bufuralol-d9 Hydrochloride (a-[[(1,1-Dimethylethyl)-amino]methyl]-7-ethyl-2-benzofuranmethanol-d9, Ro-3-4787-d9, Angium-d9) A ß-Adrenergic blocker with peripheral vasodilating activity. Group: Biochemicals. Alternative Names: a-[[(1,1-Dimethylethyl)-amino]methyl]-7-ethyl-2-benzofuranmethanol-d9; Ro-3-4787-d9; Angium-d9. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
Worldwide
Bufuralol, Hydrochloride (a-[[(1,1-Dimethylethyl)-amino]methyl]-7-ethyl-2-benzofuranmethanol, Ro-3-4787, Angium) A ß-Adrenergic blocker with peripheral vasodilating activity. Group: Biochemicals. Alternative Names: a-[[(1,1-Dimethylethyl)-amino]methyl]-7-ethyl-2-benzofuranmethanol; Ro-3-4787; Angium. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 1
Worldwide
Cdk1 Inhibitor IV, RO-3306 RO-3306 is a cell-permeable, potent and ATP-competitive inhibitor of Cdk1 (Ki = 35 nM and 110 nM for Cdk1/B1 and Cdk1/A, respectively). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
InSolution Cdk1 Inhibitor IV, RO-3306 The Cdk1 Inhibitor IV, RO-3306 controls the biological activity of Cdk1. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione 3,4-Di(1H-indol-3-yl)-1H-pyrrole-2,5-dione. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2,3-bis(1H-Indol-3-yl)maleimide; J-004072; DTXSID30152324; BRD-K49448285-001-01-3; DS-0027; AC1L1DL8; CCG-206739; AX8117363; Ro-31-6233; Bisindolyl deriv. 3. Product Category: Heterocyclic Organic Compound. CAS No. 119139-23-0. Molecular formula: C20H13N3O2. Mole weight: 327.343g/mol. IUPACName: 3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione. Canonical SMILES: C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54. Product ID: ACM119139230. Alfa Chemistry — ISO 9001:2015 Certified. Categories: bisindolylmaleimide iv. Alfa Chemistry. 3
8-OH-DPAT 8-OH-DPAT (8-Hydroxy-DPAT) is an agonist that has selectivity for 5-HT1A receptor (pIC50 = 8.19). It was subsequently found to be a serotonin reuptake inhibitor and a 5-HT7 receptor agonist as well. Studies showed that it exhibited antidepressant, anxiolytic and other properties. Uses: Serotonin receptor agonists. Synonyms: 8-HYDROXY-2-(DI-n-PROPYLAMINO)TETRALIN; 7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-ol; CHEMBL56; Ro-31-8220 in solution; 8-Hydroxy-DPAT. Grades: 99.03 %. CAS No. 78950-78-4. Molecular formula: C16H25NO. Mole weight: 247.38. BOC Sciences 10
Bufuralol hydrochloride Bufuralol (Ro-34787) is a β-adrenoceptor blocker with partial peripheral vasodilating activity and is potentially useful for the treatment of hypertension. It is primarily metabolized by cytochrome P450 (CYP) isoform CYP2D6, with CYP1A2 and CYP2C19 also contributing to 1'-hydroxylation. Most beta blockers are aryloxypropanolamine-based, in this rare exception, the benzofuran oxygen is part of a ring instead of derived from the epichlorohydrin precursor. Synonyms: Ro 3-4787. Grades: ≥95%. CAS No. 60398-91-6. Molecular formula: C16H23NO2·HCl. Mole weight: 297.8. BOC Sciences 10
Cilazapril Cilazapril is a very potent and highly effective angiotensin-converting enzyme inhibitor (ACE inhibitor). It is used for the treatment of hypertension and congestive heart failure. lt is a monoethyl ester. It is a prodrug that is hydrolyzed after absorption to its main metabolite cilazaprilat by non-specific esterases. It is known that the diacid form is more potent. It has been listed. Uses: Cilazapri is used for the treatment of hypertension and congestive heart failure. Synonyms: Cilazapril; Ro 34-2848; Ro-34-2848; Ro34-2848. 7-[ (2-amino-2-carboxylatoethyl) thio]-2-[[ (2, 2-dimethylcyclopropyl) carbonyl]amino]hept-2-enoate; 6H-Pyridazino[1, 2-a][1, 2]diazepine-1-carboxylic acid, 9-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, (1S,9S)-;6H-Pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid, 9-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]octahydro-10-oxo-, [1S-[1α,9α(R*)]]-;Ro 31-2848;(1S,9S)-9-[(S)-1-Ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid; Inhibace; Vascace; Cilazaprilum; (4S, 7S)-7-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-6-oxo-1, 2, 3, 4, 7, 8, 9, 10-octahydropyridazino[1, 2-a]diazepine-4-carboxylic acid. Grades: >98%. CAS No. 88768-40-5. Molecular formula: C22H31N3O5. Mole weight: 417.50. BOC Sciences 7
MKC-1 MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in cell cycle arrest at the G2/M phase and apoptosis. In addition, this agent has been shown to inhibit the activities of the oncogenic kinase Akt, the mTOR pathway, and importin-beta, a protein essential to the transport of other proteins from the cytosol into the nucleus. Synonyms: MKC1; MKC 1; R 440; Ro 317453; Ro-317453; Ro317453; 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)-1H-pyrrole-2,5-dione. CAS No. 125313-92-0. Molecular formula: C22H16N4O4. Mole weight: 400.39. BOC Sciences 11
MKC-1 MKC-1 is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the formation of the mitotic spindle, which may result in cell cycle arrest at the G2/M phase and apoptosis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MKC1; MKC 1; MKC-1; R 440; R-440; R440; Ro 317453; Ro-317453; Ro317453. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 125313-92-0. Molecular formula: C22H16N4O4. Mole weight: 400.39. Purity: >98%. IUPACName: 3-(1-methyl-1H-indol-3-yl)-4-(1-methyl-6-nitro-1H-indol-3-yl)-1H-pyrrole-2,5-dione. Canonical SMILES: O=C(C(C1=CN(C)C2=C1C=CC=C2)=C3C4=CN(C)C5=C4C=CC([N+]([O-])=O)=C5)NC3=O. Product ID: ACM125313920. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Mk 153 Shoulder-Launched Multipurpose Assault Weapon. Alfa Chemistry.
MKC-1 MKC-1 (Ro-31-7453) is an orally active and potent cell cycle inhibitor with broad antitumor activity. MKC-1 inhibits the Akt/mTOR pathway. MKC-1 arrests cellular mitosis and induces cell apoptosis by binding to a number of different cellular proteins including tubulin and members of the importin β family [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro-31-7453. CAS No. 125313-92-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13691. MedChemExpress MCE
RO314724 RO314724 is a MMP and HDAC inhibitor. Synonyms: RO 314724; RO-314724; (R)-N-(N-(2-(2-(Hydroxyamino)-2-oxoethyl)-4-methyl-1-oxopentyl)-L-leucyl)-L-alanine ethyl ester. CAS No. 112105-54-1. Molecular formula: C19H35N3O6. Mole weight: 401.50. BOC Sciences 11
RO31-8220 Ro 31-8220 is a PKC-inhibitor, which inhibits stimulated fluid pinocytosis of human PMNs induced by the PKC-activators phorbol myristate acetate or diacylglycerols by 95%. Ro-31-8220 showed the apoptotic effect on HL-60 cells, which was mediated by a well-characterized transduction process of apoptotic signals. Moreover, the ability of Ro-31-8220 to induce apoptotic activation was completely inhibited by the over-expression of the apoptotic suppressor gene, Bcl-2, in the cells. Uses: Enzyme inhibitors. Synonyms: RO31-8220; RO 31-8220; RO-31-8220; RO318220. Grades: 0.98. CAS No. 125314-64-9. Molecular formula: C25H23N5O2S. Mole weight: 457.552. BOC Sciences 10
Ro 31-8220 Mesylate Ro 31-8220 inhibits rat brain PKC activity with IC50 of 23 nM, and does not show any high degree of selectivity between PKC-α, PKC-β, PKC-γ, and PKC-&epsilon. Synonyms: RO31-8220; RO 31-8220; RO31-8220; RO318220; RO-318220; RO 318220; RO31-8220 mesylate; Bisindolylmaleimide IX; BIM IX.Bisindolylmaleimide IX Mesylate. Grades: >98%. CAS No. 138489-18-6. Molecular formula: C25H23N5O2S.CH4O3S. Mole weight: 553.65. BOC Sciences 10
RO3201195 RO3201195 is an orally bioavailable and highly selective inhibitor of p38 MAPK which was selected for advancement into Phase I clinical trials. Synonyms: RO-3201195; RO 3201195; (5-Amino-1-(4-fluoro-phenyl)-1H-pyrazol-4-yl)-(3-(2,3-dihydroxy-propoxy)-phenyl)-methanone. CAS No. 249937-52-8. Molecular formula: C19H18FN3O4. Mole weight: 371.36. BOC Sciences 11
Ro 32-0432 hydrochloride Ro 32-0432 hydrochloride is a selective and orally active inhibitor of PKC displaying a 10-fold greater selectivity for PKC-&alpha (IC50 = 9.3 nM); and a 4-fold greater selectivity for PKC-βI over PKC- &epsilon (IC50 = 108 nM). Synonyms: Ro 32-0432; Ro 320432; Ro-32-0432. 3-[(8S)-8-[(Dimethylamino)methyl]-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione hydrochloride; RO 32-0432 HCL; RO 32-0432 HYDROCHLORIDE; BISINDOLYLMALEIMIDE XI, HCL; BISINDOLYLMALEIMIDE XI HYDROCHLORIDE; BISINDOLYLMALEIMIDE XL, HCL; BISINDOYLMALEIMIDE XI HYDROCHLORIDE. Grades: ≥99% by HPLC. CAS No. 151342-35-7. Molecular formula: C28H28N4O2.HCl. Mole weight: 489.01. BOC Sciences 10
Ro 32-3555 Ro 32-3555 is a selective inhibitor of collagenases over the related human matrix metalloproteinases stromelysin 1, and gelatinases A and B (Ki values of 527, 154 and 59 nM, respectively). It inhibits both the cartilage and bone changes in this mouse model of OA, and thus shows great potential as a treatment of OA in humans. Synonyms: Ro-32-3555; Ro 32 3555; Ro323555; (αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidinebutanamide; Cipemastat; Ro32-3555; 190648-49-8; GFUITADOEPNRML-SJORKVTESA-N; UNII-02HQ4TYQ60; Trocade. Grades: ≥97% by HPLC. CAS No. 190648-49-8. Molecular formula: C22H36N4O5. Mole weight: 436.55. BOC Sciences 10
Ro5203280 Ro5203280 is a small-molecular PLK1 inhibitor. Ro5203280 shows a high efficacy for suppressing nasopharyngeal carcinoma growth with low toxicity in mouse studies. It suppresses nasopharyngeal carcinoma growth by inducing G2-M arrest and mitotic arrest and finally induces apoptosis through inhibiting PLK1 phosphorylation. Ro5203280 may be a potential chemotherapeutic agent for nasopharyngeal carcinoma treatment. Synonyms: RO3280; RO-3280; RO 3280; Ro5203280; Ro-5203280; Ro 5203280. Grades: 0.98. CAS No. 1062243-51-9. Molecular formula: C27H35F2N7O3. Mole weight: 543.62. BOC Sciences 10
1-Methoxy-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol 1-Methoxy-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1-methoxy-3-(2-methyl-5-nitro-imidazol-1-yl)-propan-2-ol; Roll-3696; 1-methoxy-3-(2-methyl-5-nitroimidazol-1-yl)propan-2-ol. Product Category: Heterocyclic Organic Compound. CAS No. 60174-20-1. Molecular formula: C8H13N3O4. Mole weight: 215.207 g/mol. Purity: 0.96. IUPACName: 1-(2-hydroxy-3-methoxypropyl)-2-methyl-5-nitroimidazole. Product ID: ACM60174201. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
Ablukast Ablukast is a leuktriene receptor antagonist that acts as an anti-asthmatic. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ablukast; Ro 23-3544; Ro-23-3544; Ro23-3544; Ro 233544; Ro-233544; Ro233544; Ro 23-3544/000. Product Category: Antagonists. Appearance: Solid powder. CAS No. 96566-25-5. Molecular formula: C28H34O8. Mole weight: 498.57. Purity: >98%. IUPACName: 2H-1-Benzopyran-2-carboxylic acid, 6-acetyl-7-((5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentyl)oxy)-3,4-dihydro-, (+-)-. Canonical SMILES: O=C(C1CCC2=CC(C(C)=O)=C(OCCCCCOC3=CC=C(C(C)=O)C(O)=C3CCC)C=C2O1)O. Product ID: ACM96566255-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
CBF beta-Runx1 Inhibitor II, Ro5-3335 ([7-chloro-5-(2-pyrryl)-3H-1,4 benzodiazapin-2-(H)-one], Ro53335, CBFalpha-CBFbeta Inhibitor II) A cell-permeable benzodiazepine that suppresses CBFalpha/Runx1-CBFbeta transactivation activity (25uM; 293-0 cells) via direct bindings to both subunits of the heterodimeric transcription factor complex. Shown to inhibit oncogenic fusion CBFB-MYH11-, TEL-RUNX1-, and RUNX1-ETO-, dependent leukemia cells proliferation (IC50 = 1.1 to 21.7uM) in vitro and more effectively reduce peripheral blood c-kit+ population (300mg/kg/d via animal feed) than Cytarabine in a murine Cbfb-MYH11 leukemia model in vivo. Comparing to CBFbeta-Runx1 Inhibitor I, Ro5-3335 modulates the Runx1-CBFbeta heterodimer formation without completely disrupting the subunits interaction. Group: Biochemicals. Grades: Highly Purified. CAS No. 30195-30-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
Netupitant Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). SP is found in neurons of vagal afferent fibers innervating the brain-stem nucleus tractus solitarii and the area postrema, which contains the chemoreceptor trigger zone (CTZ), and may be elevated in response to chemotherapy. The NK-receptor is a G-protein receptor coupled to the inositol phosphate signal-transduction pathway and is found in both the nucleus tractus solitarii and the area postrema. On 10/10 2014 FDA approved netupitant for the treatment of nausea and vomiting in patients undergoing cancer chemotherapy. Synonyms: AGE94200; AGE-94200; AGE 94200;Ro 67-3189; Ro-67-3189; Ro67-3189; CHEBI441603; CID6451149; D05152; UNII-7732P08TIR, CHEMBL206253, AG-E-94200, Netupitant. Grades: >98%. CAS No. 290297-26-6. Molecular formula: C30H32F6N4O. Mole weight: 578.603. BOC Sciences 8
PFI-3 PFI-3, a potent and selective SMARCA2/4 bromodomain inhibitor, is a cell-permeable probe that binds avidly to the structurally-similar SMARCA4 bromodomain (Kd= 89 nM) and PB1(bromodomain 5) (Kd= 48 nM). Synonyms: PFI-3; PFI 3; PFI3. (E)-1-(2-hyd roxyphenyl)-3-[(1R,4R)-2-pyridin-2-yl-2,5-diazabicyclo[2.2.1]heptan-5-yl]prop-2-en-1-one; PF-06687252; PFI-3 compound; PF 06687252; PF06687252. Grades: >98%. CAS No. 1819363-80-8. Molecular formula: C19H19N3O2. Mole weight: 321.38. BOC Sciences 8
Ro5-3335 Ro5-3335 Inhibitor. Uses: Scientific use. Product Category: T4687. CAS No. 30195-30-3. TARGETMOL CHEMICALS
ROC-325 ROC-325 is a lysosomal-mediated autophagy inhibitor. It exhibits superior preclinical anticancer activity compared with hydroxychloroquine (HCQ). Uses: Antineoplastic agents. Synonyms: ROC 325; ROC325; 1-[2-[2-[(7-chloroquinolin-4-yl)amino]ethyl-methylamino]ethylamino]-4-methylthioxanthen-9-one. CAS No. 1859141-26-6. Molecular formula: C28H27ClN4OS. Mole weight: 503.06. BOC Sciences 11
ROC-325 ROC-325 is a potent and orally active autophagy inhibitor with a strong anticancer activity. ROC-325 induces the deacidification of lysosomes, accumulation of autophagosomes, and disrupted autophagic flux. ROC-325 also induces renal cell carcinoma apoptosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1859141-26-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103706. MedChemExpress MCE
WUN40378 WUN40378 is compound first reported in PCT Int. Appl. (2019), WO 201909959, in which it was described as CBFβ-RUNX1 inhibitor. WUN40378 is very similar to Ro 5-3335 but with an F instead of Cl. WUN40378 is also analog of Ro 24-7429. Uses: Designed for use in research and industrial production. Additional or Alternative Names: WUN40378; WUN 40378; WUN-40378; Ro5-3335 analog; Ro 5-3335 analog; Ro 5-3335 analog; Ro 24-7429 analog; Ro 24-7429 analog; Ro24-7429 analog. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 2328140-37-8. Molecular formula: C13H10FN3O. Mole weight: 243.24. Purity: >98%. IUPACName: 7-fluro-1,3-dihydro-5-(1H-pyrrol-2yl)-2H-1,4-benzodiazepin-2-one. Canonical SMILES: O=C1NC2=CC=C(F)C=C2C(C3=CC=CN3)=NC1. Product ID: ACM2328140378. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.

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