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| Product | Description | |
|---|---|---|
| Rocaglamide | ?96% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Rocaglamide | Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-?B activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia[1][2][3]. Uses: Scientific research. Group: Natural products. Alternative Names: Roc-A. CAS No. 84573-16-0. Pack Sizes: 10 mM * 1 mL; 500 ?g; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19356. |  |
| Rocaglamide | Rocaglamide (Roc-A) is isolated from the genus Aglaia and can be used for coughs, injuries, asthma and inflammatory skin diseases. Rocaglamide is a potent inhibitor of NF-κB activation in T-cells. Rocaglamide is a potent and selective heat shock factor 1 (HSF1) activation inhibitor with an IC50 of ~50 nM. Rocaglamide inhibits the function of the translation initiation factor eIF4A. Rocaglamide also has anticancer properties in leukemia. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (1R)-2,3,3a,8b-Tetrahydro-1α,8bβ-dihydroxy-6,8-dimethoxy-3aβ-(4-methoxyphenyl)-N,N-dimethyl-3β-phenyl-1H-cyclopenta[b]benzofuran-2α-carboxamide. Product Category: Inhibitors. CAS No. 84573-16-0. Molecular formula: C29H31NO7. Mole weight: 505.6. Purity: 95%+. Product ID: ACM84573160. Alfa Chemistry ISO 9001:2015 Certified. |  |
| ROCAGLAMIDE | Rocaglamide is the first cyclopenta[b]benzofuran derivative extracted from Aglaia elliptifolia in 1982 by King and colleagues. Its IC50 value is ~50 nM for the heat shock reporter. It has antileukemic activity and displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. It is an immunosuppressant that inhibits activation of NF-kB and NF-AT. It markedly inhibited tumor growth from Huh-7 cells propagated in severe combined immunodeficient mice. It induces apoptosis in various human leukemia cell lines and in acute lymphoblastic leukemia, chronic myeloid leukemia and acute myeloid leukemia cells. It inhibit protein synthesis without affecting DNA or RNA synthesis. Uses: Rocaglamide has antileukemic activity and displays potent insecticidal, antifungal, anti-inflammatory and anticancer activities. it is an immunosuppressant that inhibits activation of nf-kb and nf-at. it inhibit protein synthesis without affecting dna or rna synthesis. Synonyms: Rocaglamide; Rocaglamide A; RocA; NSC 326408. (1R,2R,3S,3aR,8bS)-2,3,3a,8b-Tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-1H-cyclopenta[b]benzofuran-2-carboxamide; NSC 326408; Roc-A; Rocaglamide A; 1H-Cyclopenta(b)benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-6,8-dimethoxy-3a-(4-methoxyphenyl)-N,N-dimethyl-3-phenyl-, (1R,2R,3S,3aR,8bS)-; [1R-(1α. Grade: 95%. CAS No. 84573-16-0. Molecular formula: C29H3 |  |
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