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| Product | Description | |
|---|---|---|
| Roflumilast | Roflumilast (APTA-2217) is a selective PDE4 inhibitor with IC 50 s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1 , PDEA4 , PDEB1 , and PDEB2 , respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Uses: Scientific research. Group: Signaling pathways. Alternative Names: APTA-2217; BYK 20869; B9302-107. CAS No. 162401-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15455. |  |
| Roflumilast | Roflumilast is a selective, long-acting inhibitor of the enzyme PDE-4 as anti-inflammatory effects for the treatment of inflammatory conditions of the lungs such as asthma, and chronic obstructive pulmonary disease (COPD). Group: Fluorinated apis. Alternative Names: Daliresp. CAS No. 162401-32-3. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.2. Appearance: White to off-white solid powder. Purity: 0.98. IUPACName: 3-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide. Catalog: OFC162401323. |  |
| Roflumilast | Selective phosphodiesterase 4 (PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107; BY 217; BYK 20869. Grades: Highly Purified. CAS No. 162401-32-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14Cl2F2N2O3, Form: Supplied as a white to off-white. US Biological Life Sciences. |  Worldwide |
| Roflumilast-d3 | Roflumilast-d3 is deuterium labeled Roflumilast. Roflumilast is a selective PDE4 inhibitor with IC50s of 0.7, 0.9, 0.7, and 0.2 nM for PDE4A1, PDEA4, PDEB1, and PDEB2, respectively, without affecting PDE1, PDE2, PDE3 or PDE5 isoenzymes from various cells. Group: Inhibitors. Alternative Names: 3-(Cyclopropylmethoxy-d3)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide; B 9302-107-d3; BY 217-d3; BYK 20869-d3. CAS No. 1189992-00-4. Molecular formula: C17H11D3Cl2F2N2O3. Mole weight: 406.23. Appearance: Crystallin Solid. Canonical SMILES: [2H]C1 (CC1)C ([2H]) ([2H])OC2=C (C=CC (C (NC3=C (Cl)C=NC=C3Cl)=O)=C2)OC (F)F. Catalog: ACM1189992004. | |
| Roflumilast-d4 | Labeled selective phosphodiesterase 4(PDE4) inhibitor. Antiasthmatic; in treatment of chronic obstructive pulmonary disease. Group: Biochemicals. Alternative Names: 3- (Cyclopropyl-d4) methoxy-N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide; B 9302-107-d4; BY 217-d4; BYK 20869-d4. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| Roflumilast-D4 | Roflumilast-D4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1398065-69-4. Molecular Formula: C17H10D4Cl2F2N2O3. Mole Weight: 407.23. Catalog: APB1398065694. |  |
| Roflumilast-d5 | Roflumilast-d5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H9D5Cl2F2N2O3. Mole Weight: 408.24. Catalog: APB12078. | |
| Roflumilast-d5 N-oxide | Roflumilast-d5 N-oxide. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H9D5Cl2F2N2O4. Mole Weight: 424.24. Catalog: APB12077. | |
| Roflumilast Dimer | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. CAS No. 1352122-37-2. Molecular formula: C29H24Cl2F4N2O6. Mole weight: 643.42. |  |
| Roflumilast Impurity 1 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast; Roflumilast Impurity A. Grades: > 95%. CAS No. 162401-43-6. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22. | |
| Roflumilast Impurity 1 | Roflumilast Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 292135-78-5. Molecular Formula: C17H14Cl2F2N2O4. Mole Weight: 419.21. Catalog: APB292135785. | |
| Roflumilast Impurity 10 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H16F2N2O3. Mole weight: 334.33. | |
| Roflumilast Impurity 11 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.21. | |
| Roflumilast Impurity 2 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.12. | |
| Roflumilast Impurity 2 | Roflumilast Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1352122-37-2. Molecular Formula: C29H24Cl2F4N2O6. Mole Weight: 643.41. Catalog: APB1352122372. | |
| Roflumilast Impurity 3 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)benzamide; 1391052-24-6; 3,4-Di(cyclopropylmethoxy) Roflumilast; BenzaMide, 3,4-bis(cyclopropylMethoxy)-N-(3,5-dichloro-4-pyridinyl)-; C20H20Cl2N2O3; 3,4-bis(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-benzamide; Roflumilast Impurity 3; DTXSID70747612; MFCD23703092; AKOS016012227; DS-6755; AC-28929; CS-0155388; C72553; A886144; A1-04290; 3,4-Bis(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)benzamide. Grades: > 95%. Molecular formula: C20H20Cl2N2O3. Mole weight: 407.29. | |
| Roflumilast Impurity 3 | Roflumilast Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1391053-75-0. Molecular Formula: C17H15ClF2N2O3. Mole Weight: 368.76. Catalog: APB1391053750. | |
| Roflumilast Impurity 4 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C14H8Cl2F4N2O3. Mole weight: 399.13. | |
| Roflumilast Impurity 4 | Roflumilast Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C16H10F2O8. Mole Weight: 368.24. Catalog: APB12076. | |
| Roflumilast Impurity 5 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.21. | |
| Roflumilast Impurity 6 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C16H10F2O8. Mole weight: 368.25. | |
| Roflumilast Impurity 7 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14BrClF2N2O3. Mole weight: 447.67. | |
| Roflumilast Impurity 8 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22. | |
| Roflumilast Impurity 9 | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Grades: > 95%. Molecular formula: C17H14Cl2F2N2O3. Mole weight: 403.22. | |
| Roflumilast Impurity B | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: 4-O-Des(difluoromethyl) Roflumilast; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. Grades: > 95%. CAS No. 475271-62-6. Molecular formula: C16H14Cl2N2O3. Mole weight: 353.20. | |
| Roflumilast Impurity D | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Benzoic acid, 3-(cyclopropylmethoxy)-4-hydroxy-. CAS No. 1243391-44-7. Molecular formula: C11H12O4. Mole weight: 208.21. | |
| Roflumilast Impurity E | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3-O-Decyclopropyl Roflumilast; Roflumilast metabolite M05; 3-(Hydroxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide. CAS No. 1391052-76-8. Molecular formula: C13H8Cl2F2N2O3. Mole weight: 349.11. | |
| Roflumilast Impurity H | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: 3,4-Bis(difluoromethoxy) Roflumilast; Bis-difluoromethoxy Roflumilast impurity. CAS No. 162401-30-1. Molecular formula: C14H8Cl2F4N2O3. Mole weight: 399.12. | |
| Roflumilast N-Oxide | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl- methoxybenzamide; 3,5-Dichloro-4-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamido)pyridine 1-oxide. Grades: > 95%. CAS No. 292135-78-5. Molecular formula: C17H14Cl2F2N2O4. Mole weight: 419.21. | |
| Roflumilast N-Oxide | Roflumilast-N-oxide is the active metabolite of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Cyclopropylmethoxy) -N- (3, 5-dichloro-1-oxido-4-pyridinyl) -4- (difluoromethoxy) benzamide; N-(3,5-Dichloro-1-oxopyridin-4-yl)-4-difluoromethoxy-3-cyclopropyl-methoxybenzamide. Grades: Highly Purified. CAS No. 292135-78-5. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 3,4-Bis(difluoromethoxy) Roflumilast | 3,4-Bis(difluoromethoxy) Roflumilast is an impurity of the antiasthmatic drug Roflumilast. Group: Biochemicals. Alternative Names: N- (3, 5-Dichloro-4-pyridinyl) -3, 4-bis (difluoromethoxy) benzamide. Grades: Highly Purified. CAS No. 162401-30-1. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3,4-Di(cyclopropylmethoxy) Roflumilast | 3,4-Di(cyclopropylmethoxy) Roflumilast is an impurity of Roflumilast. Group: Biochemicals. Alternative Names: 3,4-Di(cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)benzamide. Grades: Highly Purified. CAS No. 1391052-24-6. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| 3-(CyclopropylMethoxy)-4-(difluoroMethoxy)benzaldehyde; RofluMilast interMediate | Cas No. 151103-09-2. | |
| 3-O-Decyclopropyl Roflumilast | O-Decyclopropyl Roflumilast is an impurity of Roflumilast. Group: Biochemicals. Alternative Names: 3- (Hydroxy) -N- (3, 5-dichloro-4-pyridinyl) -4- (difluoromethoxy) benzamide. Grades: Highly Purified. CAS No. 1391052-76-8. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast | 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast is a positional isomeric impurity of Roflumilast. Group: Biochemicals. Alternative Names: 4- (Cyclopropylmethoxy) -N- (3, 5-dichloro-4-pyridinyl) -3- (difluoromethoxy) benzamide. Grades: Highly Purified. CAS No. 162401-43-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 4-O-Des(difluoromethyl) Roflumilast | 4-O-Des(difluoromethyl) Roflumilast is an impurity in the preparation of Roflumilast. Group: Biochemicals. Alternative Names: 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-hydroxybenzamide. Grades: Highly Purified. CAS No. 475271-62-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| 5-Dechloro Roflumilast | 5-Dechloro Roflumilast is an impurity of Roflumilast. Group: Biochemicals. Alternative Names: N- (3-Chloropyridin-4-yl) -3- (cyclopropylmethoxy) -4- (difluoromethoxy) benzamide. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| 5-Dechloro Roflumilast | An impurity of Roflumilast. Roflumilast is a selective, long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4). Synonyms: Benzamide, N-(3-chloro-4-pyridinyl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)-. Grades: > 95%. CAS No. 1391053-75-0. Molecular formula: C17H15ClF2N2O3. Mole weight: 368.77. | |
| 3, 4-Bis (difluoromethoxy) benzaldehyde | 3, 4-Bis (difluoromethoxy) benzaldehyde is an impurity of the antiasthmatic drug Roflumilast. 3, 4-Bis (difluoromethoxy) benzaldehyde is used in the preparation of diphenylethylene compounds as PDE4 (phosphodiesterase-4) inhibitors for treatment of cancer, CNS disorders, and inflammatory disorders. Group: Biochemicals. Grades: Highly Purified. CAS No. 127842-54-0. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| 3-(Cyclopropylmethoxy)-3-hydroxybenzoic Acid Methyl Ester | 3-(Cyclopropylmethoxy)-3-hydroxybenzoic Acid Methyl Ester is an intermediate in the synthesis of Roflumilast (R639700), an selective phosphodiesterase 4(PDE4) inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 848574-60-7. Pack Sizes: 100mg, 1g. Molecular Formula: C12H14O4. US Biological Life Sciences. | Worldwide |
| 3- (Cyclopropylmethoxy) -4- (methoxymethoxy) benzoic Acid | 3- (Cyclopropylmethoxy) -4- (methoxymethoxy) benzoic Acid is an impurity formed in the synthesis of Roflumilast (R639700), an selective phosphodiesterase 4(PDE4) inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 250mg. Molecular Formula: C13H16O5. US Biological Life Sciences. | Worldwide |
| Temsirolimus Impurity 1 | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: 7-O-Desmethyl Temsirolimus; (7ξ)-7-O-Demethyl-rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]. Grades: > 95%. CAS No. 408321-08-4. Molecular formula: C55H85NO16. Mole weight: 1016.29. | |
| Temsirolimus Impurity 2 | One impurity of Roflumilast, which is a PDE4 inhibitor and has been found to be effective as antiasthmatic agent. Synonyms: Temsirolimus Isomer C. Grades: > 95%. CAS No. 1027067-40-8. Molecular formula: C56H87NO16. Mole weight: 1030.31. | |
| Veratrole | Veratrole is common reagent in organic synthesis such as the synthesis of arizonins B1 and C1. Also used in the synthesis of pharmacophores of salmeterol and roflumilast as dual β2-adrenoreceptor agonists-PDE4 inhibitors. Group: Biochemicals. Grades: Highly Purified. CAS No. 91-16-7. Pack Sizes: 10g, 25 g. Molecular Formula: C8H10O2. US Biological Life Sciences. | Worldwide |
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